Page last updated: 2024-08-16

trimethoprim and 2,4-diamino-5,6-dihydro-6,6-dimethyl-5-(4'-methoxyphenyl)-s-triazine

trimethoprim has been researched along with 2,4-diamino-5,6-dihydro-6,6-dimethyl-5-(4'-methoxyphenyl)-s-triazine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD1
Crippen, GM; Ghose, AK2
Crippen, GM1
Cichero, E; Costi, MP; Gazzarrini, S; Loddo, R; Moroni, A; Naesens, L; Santucci, M; Tasso, B; Tonelli, M1

Other Studies

5 other study(ies) available for trimethoprim and 2,4-diamino-5,6-dihydro-6,6-dimethyl-5-(4'-methoxyphenyl)-s-triazine

ArticleYear
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines

1984
General distance geometry three-dimensional receptor model for diverse dihydrofolate reductase inhibitors.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:7

    Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography; Folic Acid Antagonists; Liver; Models, Chemical; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Rats; Structure-Activity Relationship; Triazines

1984
Combined distance geometry analysis of dihydrofolate reductase inhibition by quinazolines and triazines.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:7

    Topics: Chemical Phenomena; Chemistry; Folic Acid Antagonists; Molecular Conformation; Quinazolines; Streptococcus; Structure-Activity Relationship; Triazines

1983
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.
    Journal of medicinal chemistry, 1997, Sep-26, Volume: 40, Issue:20

    Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin

1997
Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Antiviral Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Proguanil; Respiratory Syncytial Viruses; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines

2017