trimethoprim--sulfamethoxazole-drug-combination and thienamycin

The authors have tested the sensibility to three new quinolones of forty one strains of mycobacteria belonging to seven different species. They have observed, in particular, susceptibility for the species M. tuberculosis, M. fortuitum, M. kansasii, M. marinum and M. xenopi to ciprofloxacin and ofloxacin and a limited sensibility for these same species to pefloxacin. In association with others antibiotics, amikacin, erythromycin, thienamycin, trimethoprim-sulfamethoxazole, the three have shown some additive effects and in a few cases synergistic effects.

Topics: Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Drug Synergism; Erythromycin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Sulfamethoxazole; Thienamycins; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination