trimethoprim--sulfamethoxazole-drug-combination and mebhydroline

One hundred and fifty-one children aged 2-6 years old suffering from chronic rhinitis were followed and treated for periods of 3-6 months. Seventy-five children were treated with antihistamines (AH) and 76 with antibiotics (AB). Significant statistic difference was found between pre-school children and school children. The differences were both with the nature of the symptoms, and reaction to treatment. While 49% of the school children recovered with AH treatment, only 14% of the pre-school children did. On the other hand, 58% of the pre-school children recovered with AB treatment while only 35% of the older children did. From our results it is clear that in many children bacterial infection is the cause for chronic rhinitis. In pre-school children it is the main cause, while in older children it is the cause in about a third of the cases. It is also important to remember that although allergy might be the basic reason for rhinitis, in certain age groups a secondary bacterial infection might interfere with the efficiency of antiallergic treatment.

Topics: Age Factors; Astemizole; Bacterial Infections; Carbolines; Child; Child, Preschool; Chronic Disease; Follow-Up Studies; Health Status; Histamine H1 Antagonists; Humans; Linear Models; Prognosis; Recurrence; Rhinitis; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Suppuration; Trimethoprim, Sulfamethoxazole Drug Combination