Page last updated: 2024-08-22

trimethaphan and phenylephrine

trimethaphan has been researched along with phenylephrine in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (38.24)	18.7374
1990's	5 (14.71)	18.2507
2000's	15 (44.12)	29.6817
2010's	1 (2.94)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
dold, GM; Gamache, FW; Myers, RE	1
Bishop, VS; Cox, BF	1
DeRiso, J; Ouyang, A; Rothstein, RD	1
Fukui, T; Nishida, M; Okada, Y; Shima, T; Yamada, T; Yamane, K; Yoshida, A	1
Baertschi, AJ; Guyenet, PG; Hashemzadeh-Gargari, H	1
Matsukawa, T; Miyajima, E; Shionoiri, H; Tochikubo, O; Uneda, S; Yamada, Y	1
Bacher, JD; Goldstein, DS; Keiser, HR; Kelly, GD; Stull, R; Zimlichman, R	1
Deacock, AR	1
Gersh, BJ; Prys-Roberts, C; Reuben, SR; Schultz, DL	1
Carey, JP; Chin, SC; Connolly, JE; Heber, R; List, JW; Stemmer, EA	1
Harioka, T; Hatano, Y; Mori, K; Toda, N	1
Shiff, S; Snape, WJ	1
Leenen, FH; White, M	1
Black, BK; Costa, F; Jordan, J; Robertson, D; Shannon, JR	1
Biaggioni, I; Black, B; Costa, F; Diedrich, A; Jordan, J; Robertson, D; Shannon, JR	1
Jones, PP; Jordan, J; Keisling, GA; Quaife, RA; Seals, DR; Shannon, JR; Shapiro, LF	1
Black, BK; Diedrich, A; Jordan, J; Robertson, D; Shannon, JR	1
Hohenbleicher, H; Jordan, J; Luft, FC; Schröder, C; Sharma, AM; Tank, J; Toka, H	1
Arnold, G; Diedrich, A; Franke, G; Goldstein, DS; Jordan, J; Lipp, A; Luft, FC; Schröder, C; Sharma, AM; Stoffels, M; Tank, J	1
Crandall, CG; Iwasaki, K; Levine, BD; Wilson, TE; Zhang, R; Zuckerman, JH	1
Bangash, MF; Dempsey, JA; Morgan, BJ; Przybyłowski, T; Reichmuth, K; Skatrud, JB	1
Christou, DD; Jones, PP; Jordan, J; Seals, DR	1
Christou, DD; Jones, PP; Seals, DR	1
BOLTAX, AJ; GREENE, MA; NIV, M; SCHERR, ES	1
BOLTAX, AJ; GREENE, MA; NIV, M; ROGOW, E	1
ADAMS, JE; ELLIOTT, HW; KARLSBERG, P	1
CRANDELL, DL; GREISS, FC	1
Christou, DD; Jones, PP; Pimentel, AE; Seals, DR	1
Christou, DD; Diedrich, A; Jones, PP; Jordan, J; Robertson, D; Seals, DR	1
Biaggioni, I; Choi, L; Diedrich, A; Farley, G; Gamboa, A; Jordan, J; Paranjape, S; Pohar, B; Shibao, C	1
Eisenach, JH; Hesse, C; Joyner, MJ; Moyer, TP; Nicholson, WT; Sviggum, HP; Wilkins, BW	1
Levine, BD; Zhang, R	1
Charkoudian, N; Eisenach, JH; Hesse, C; Joyner, MJ; Moyer, TP; Nicholson, WT; Sviggum, HP; Wilkins, BW	1
Curry, TB; Eisenach, JH; Hart, EC; Hesse, C; Joyner, MJ; Nicholson, WT; Penheiter, AR; Schroeder, DR; Turner, ST	1

Trials

9 trial(s) available for trimethaphan and phenylephrine

Article	Year
Aging and cardiovascular responsiveness to beta-agonist in humans: role of changes in beta-receptor responses versus baroreflex activity. Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:5 Topics: Adult; Aged; Aging; Atropine; Baroreflex; Female; Forearm; Heart Rate; Hemodynamics; Humans; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Phenylephrine; Receptors, Adrenergic, beta; Regional Blood Flow; Sex Characteristics; Trimethaphan; Vascular Resistance	1994
Catechol-o-methyltransferase and blood pressure in humans. Circulation, 2002, Jul-23, Volume: 106, Issue:4 Topics: Baroreflex; Blood Pressure; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ganglionic Blockers; Humans; Kinetics; Male; Middle Aged; Nitriles; Nitroprusside; Phenylephrine; Shy-Drager Syndrome; Sympathomimetics; Trimethaphan; Yohimbine	2002
Autonomic neural control of dynamic cerebral autoregulation in humans. Circulation, 2002, Oct-01, Volume: 106, Issue:14 Topics: Adult; Autonomic Nervous System; Blood Flow Velocity; Blood Pressure; Brain; Cerebrovascular Circulation; Female; Ganglionic Blockers; Heart Rate; Humans; Lower Body Negative Pressure; Male; Middle Cerebral Artery; Phenylephrine; Reference Values; Trimethaphan; Ultrasonography, Doppler, Transcranial; Vasoconstrictor Agents	2002
Mechanisms of the cerebrovascular response to apnoea in humans. The Journal of physiology, 2003, Apr-01, Volume: 548, Issue:Pt 1 Topics: Adrenergic alpha-Agonists; Adult; Apnea; Cerebrovascular Circulation; Female; Ganglionic Blockers; Hemodynamics; Humans; Hypercapnia; Hyperoxia; Hypocapnia; Male; Middle Cerebral Artery; Phenylephrine; Respiratory Mechanics; Trimethaphan; Ultrasonography, Doppler	2003
Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:4 Topics: Abdomen; Adipose Tissue; Adult; Aged; Aging; Autonomic Nervous System; Baroreflex; Blood Pressure; Body Composition; Body Mass Index; Ganglionic Blockers; Heart; Heart Rate; Humans; Male; Middle Aged; Phenylephrine; Trimethaphan; Vagus Nerve; Vasoconstrictor Agents	2004
Contribution of endothelial nitric oxide to blood pressure in humans. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:1 Topics: Adult; Autonomic Nervous System; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Diastole; Enzyme Inhibitors; Female; Ganglionic Blockers; Humans; Male; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phenylephrine; Rest; Smoking; Systole; Trimethaphan	2007
Alternative to ganglionic blockade with anticholinergic and alpha-2 receptor agents. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2007, Volume: 17, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Blood Pressure; Cholinergic Antagonists; Dexmedetomidine; Drug Therapy, Combination; Female; Ganglion Cysts; Glycopyrrolate; Health; Humans; Male; Phenylephrine; Receptors, Adrenergic, alpha-2; Trimethaphan; Valsalva Maneuver	2007
Autonomic ganglionic blockade does not prevent reduction in cerebral blood flow velocity during orthostasis in humans. Stroke, 2007, Volume: 38, Issue:4 Topics: Adult; Autonomic Nerve Block; Baroreflex; Blood Flow Velocity; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Female; Ganglia, Sympathetic; Ganglionic Blockers; Humans; Lower Body Negative Pressure; Male; Phenylephrine; Posture; Stress, Mechanical; Sympathetic Fibers, Postganglionic; Tidal Volume; Trimethaphan; Vasoconstriction; Vasoconstrictor Agents	2007
Autonomic cardiovascular control during a novel pharmacologic alternative to ganglionic blockade. Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:5 Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nerve Block; Baroreflex; Cardiac Output; Cardiovascular System; Catecholamines; Dexmedetomidine; Female; Ganglionic Blockers; Glycopyrrolate; Heart Rate; Humans; Male; Muscarinic Antagonists; Phenylephrine; Sympathetic Nervous System; Trimethaphan	2008

Other Studies

25 other study(ies) available for trimethaphan and phenylephrine

Article	Year
Changes in cortical impedance and EEG activity induced by profound hypotension. The American journal of physiology, 1975, Volume: 228, Issue:6 Topics: Animals; Blood Pressure; Brain; Electric Conductivity; Electroencephalography; Hypotension; Macaca; Phenylephrine; Time Factors; Trimethaphan	1975
Neural and humoral mechanisms of angiotensin-dependent hypertension. The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 2 Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Dose-Response Relationship, Drug; Ganglionic Blockers; Heart Rate; Hypertension; Kidney; Nervous System Physiological Phenomena; Norepinephrine; Phenylephrine; Rabbits; Saralasin; Sympathetic Nervous System; Trimethaphan	1991
Ileocecal sphincter contraction to colonic distension: a tachykinin-mediated spinal reflex. The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1 Topics: Animals; Atropine; Blood Pressure; Cats; Cecum; Colon; Ileum; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Phenylephrine; Pressure; Reflex; Substance P; Tetrodotoxin; Trimethaphan; Vagotomy; Vasodilator Agents	1990
[Hemodynamic studies on the vertebral artery system during the vertebral arterial surgery]. No to shinkei = Brain and nerve, 1990, Volume: 42, Issue:6 Topics: Blood Pressure; Female; Homeostasis; Humans; Male; Middle Aged; Monitoring, Intraoperative; Phenylephrine; Regional Blood Flow; Sympathetic Nervous System; Trimethaphan; Vertebral Artery; Vertebrobasilar Insufficiency	1990
Baroreceptor-independent medullary mechanism for release of vasopressin during hypotension in rats. The Journal of endocrinology, 1988, Volume: 118, Issue:1 Topics: Animals; Arginine Vasopressin; Chemoreceptor Cells; Hypotension; Kynurenic Acid; Male; Medulla Oblongata; Muscimol; Nephrectomy; Pancuronium; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Trimethaphan	1988
Reduced reflex sympathoinhibition in adolescents with hypertensive parents. Japanese circulation journal, 1988, Volume: 52, Issue:11 Topics: Adolescent; Blood Pressure; Electrocardiography; Heart Rate; Humans; Hypertension; Male; Neural Inhibition; Phenylephrine; Pressoreceptors; Trimethaphan	1988
Effect of ganglion blockade on cerebrospinal fluid norepinephrine. Journal of neurochemistry, 1987, Volume: 49, Issue:5 Topics: Animals; Blood Pressure; Clonidine; Dogs; Male; Nitroprusside; Norepinephrine; Phenylephrine; Sympathetic Nervous System; Trimethaphan; Yohimbine	1987
Aspects of anaesthesia for middle ear surgery an blood loss during stapedectomy. Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:12 Topics: Adrenergic beta-Antagonists; Anesthesia, General; Ear, Middle; Epinephrine; Hemorrhage; Humans; Hypotension, Controlled; Meperidine; Microsurgery; Myringoplasty; Neuroleptanalgesia; Nitrous Oxide; Phenylephrine; Positive-Pressure Respiration; Propranolol; Stapes Surgery; Trimethaphan; Tympanoplasty	1971
The effects of halothane on the interactions between myocardial contractility, aortic impedance and left ventricular performance. II. Aortic input impedance, and the distribution of energy during ventricular ejection. British journal of anaesthesia, 1972, Volume: 44, Issue:8 Topics: Animals; Aorta; Blood Pressure; Cardiac Volume; Dogs; Halothane; Heart; Pacemaker, Artificial; Phenylephrine; Trimethaphan; Vascular Resistance	1972
The hazards of using vasoactive drugs to augment peripheral and cerebral blood flow. The American surgeon, 1969, Volume: 35, Issue:1 Topics: Anesthesia, General; Animals; Arteries; Blood Gas Analysis; Blood Pressure; Blood Volume Determination; Carbon Dioxide; Cardiac Output; Carotid Arteries; Cerebrovascular Circulation; Chlorpromazine; Dogs; Ephedrine; Femoral Artery; Hypercapnia; Infusions, Parenteral; Isoproterenol; Kidney; Metaraminol; Norepinephrine; Partial Pressure; Phenylephrine; Regional Blood Flow; Renal Artery; Surgical Procedures, Operative; Trimethaphan; Urination; Veins	1969
Trimethaphan is a direct arterial vasodilator and an alpha-adrenoceptor antagonist. Anesthesia and analgesia, 1984, Volume: 63, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Arteries; Dinoprost; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Femoral Artery; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Phenylephrine; Prostaglandins F; Trimethaphan; Vasodilator Agents	1984
Neurohumoral control of colonic motility in the rabbit. The American journal of physiology, 1983, Volume: 245, Issue:4 Topics: Animals; Atropine; Blood Pressure; Colon; Electric Conductivity; Gastrointestinal Motility; Isoproterenol; Male; Muscle Contraction; Phentolamine; Phenylephrine; Rabbits; Trimethaphan; Vasodilator Agents	1983
Uncoupling of the baroreflex by N(N)-cholinergic blockade in dissecting the components of cardiovascular regulation. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:1 Topics: Adrenergic beta-Agonists; Adult; Antihypertensive Agents; Baroreflex; Blood Pressure; Female; Heart Rate; Humans; Isoproterenol; Linear Models; Male; Nicotinic Antagonists; Nitroprusside; Phenylephrine; Receptors, Adrenergic, beta; Receptors, Nicotinic; Sympathomimetics; Trimethaphan; Vasodilator Agents	1998
Interaction of carbon dioxide and sympathetic nervous system activity in the regulation of cerebral perfusion in humans. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3 Topics: Adult; Analysis of Variance; Baroreflex; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Ganglionic Blockers; Humans; Hyperventilation; Hypocapnia; Phenylephrine; Supine Position; Sympathetic Nervous System; Tilt-Table Test; Trimethaphan; Ultrasonography, Doppler, Transcranial; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents	2000
Altered autonomic support of arterial blood pressure with age in healthy men. Circulation, 2001, Nov-13, Volume: 104, Issue:20 Topics: Adrenergic alpha-Agonists; Adult; Aged; Aging; Autonomic Nervous System; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Ganglia, Autonomic; Ganglionic Blockers; Heart; Heart Rate; Humans; Men; Phenylephrine; Trimethaphan	2001
Increased sympathetic activation in idiopathic orthostatic intolerance: role of systemic adrenoreceptor sensitivity. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Antihypertensive Agents; Baroreflex; Blood Pressure; Female; Ganglionic Blockers; Humans; Hypotension, Orthostatic; Isoproterenol; Male; Middle Aged; Nitroprusside; Norepinephrine; Phenylephrine; Posture; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathetic Nervous System; Tachycardia; Trimethaphan	2002
Heterogeneity of autonomic regulation in hypertension and neurovascular contact. Journal of hypertension, 2002, Volume: 20, Issue:4 Topics: Antihypertensive Agents; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain Stem; Cerebellum; Drug Resistance; Female; Ganglionic Blockers; Humans; Hypertension; Male; Medulla Oblongata; Middle Aged; Models, Cardiovascular; Models, Neurological; Phenylephrine; Trimethaphan	2002
Baroreflex buffering is reduced with age in healthy men. Circulation, 2003, Apr-08, Volume: 107, Issue:13 Topics: Adult; Aged; Aging; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardiovascular Physiological Phenomena; Ganglionic Blockers; Heart Rate; Humans; Male; Phenylephrine; Sympathetic Nervous System; Trimethaphan	2003
Baroreflex buffering in sedentary and endurance exercise-trained healthy men. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:6 Topics: Adrenergic alpha-Agonists; Baroreflex; Blood Pressure; Exercise; Ganglionic Blockers; Heart Rate; Humans; Male; Phenylephrine; Physical Endurance; Trimethaphan	2003
Effects of vasoactive drugs on serum electrolytes in hypertensive and normotensive humans. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 111 Topics: Blood Pressure; Blood Pressure Determination; Chlorides; Humans; Hypertension; Ions; Phenylephrine; Potassium; Sodium; Sodium, Dietary; Trimethaphan	1962
EFFECTS OF VASOACTIVE DRUGS ON PERIPHERAL VENOUS VOLUME IN HYPERTENSIVE AND NORMOTENSIVE HUMANS. The American journal of the medical sciences, 1963, Volume: 246 Topics: Blood Pressure; Blood Pressure Determination; Blood Volume; Blood Volume Determination; Heart Function Tests; Humans; Hypertension; Pharmacology; Phenylephrine; Trimethaphan; Veins	1963
EFFECT OF VARIOUS PHARMACOLOGIC AGENTS ON CEREBRAL ARTERIES. Neurology, 1963, Volume: 13 Topics: Acetylcholine; Animals; Blood Pressure; Blood Pressure Determination; Carbon Dioxide; Cerebral Arteries; Ergot Alkaloids; Haplorhini; Histamine; Isoproterenol; Lidocaine; Methysergide; Niacin; Nicotinic Acids; Papaverine; Pharmacology; Phentolamine; Phenylephrine; Research; Selective Serotonin Reuptake Inhibitors; Serotonin; Trimethaphan	1963
THERAPY FOR HYPOTENSION INDUCED BY SPINAL ANESTHESIA DURING PREGNANCY: OBSERVATIONS ON GRAVID EWES. JAMA, 1965, Mar-08, Volume: 191 Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Angiotensins; Animals; Blood Pressure; Blood Pressure Determination; Blood Volume; Dextrans; Female; Humans; Hypotension; Norepinephrine; Pharmacology; Phenylephrine; Pregnancy; Pregnancy, Animal; Research; Sheep; Trimethaphan; Uterus	1965
Women have lower tonic autonomic support of arterial blood pressure and less effective baroreflex buffering than men. Circulation, 2005, Feb-01, Volume: 111, Issue:4 Topics: Adaptation, Physiological; Adrenergic alpha-Agonists; Adult; Autonomic Nervous System; Baroreflex; Blood Pressure; Epinephrine; Female; Ganglionic Blockers; Humans; Male; Norepinephrine; Phenylephrine; Premenopause; Reference Values; Sex Characteristics; Sympathetic Nervous System; Trimethaphan; Vasopressins	2005
beta2-Adrenoceptor gene variation and systemic vasodilatation during ganglionic blockade. The Journal of physiology, 2010, Jul-15, Volume: 588, Issue:Pt 14 Topics: Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Autonomic Nerve Block; Baroreflex; Blood Pressure; Brachial Artery; Cardiac Output; Female; Ganglionic Blockers; Heart Rate; Humans; Male; Phenylephrine; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-2; Terbutaline; Trimethaphan; Vascular Resistance; Vasodilation; Young Adult	2010