trimethadione has been researched along with caffeine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jolivette, LJ; Ward, KW | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ishikawa, A; Misawa, S; Tanaka, E | 1 |
| Ishikawa, A; Kobayashi, S; Misawa, S; Tanaka, E; Uchida, E; Yamamoto, Y; Yasuhara, H | 1 |
| Izquierdo, I | 1 |
| Burba, JV | 1 |
| Cordero, JF; Oakley, GP | 1 |
| Fukao, K; Ishikawa, A; Iwasaki, Y; Osada, A; Tanaka, E; Tsuji, K; Yamamoto, Y | 1 |
| Breimer, DD; Tanaka, E | 1 |
| Etoh, H; Horie, T; Misawa, S; Nakamura, H; Narisawa, C; Ohkawa, H; Sawa, Y; Tadano, K; Tanaka, E | 1 |
3 review(s) available for trimethadione and caffeine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug exposure during pregnancy: some epidemiologic considerations.
Topics: Abnormalities, Drug-Induced; Benzodiazepines; Caffeine; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Female; Humans; Hydantoins; Immunosuppressive Agents; Lithium; Lithium Carbonate; Phenothiazines; Pregnancy; Pyridoxine; Registries; Risk; Rubella Vaccine; Solvents; Spermatocidal Agents; Trimethadione; Valproic Acid | 1983 |
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Erythromycin; Humans; Liver Diseases; Liver Function Tests; Trimethadione | 1997 |
12 other study(ies) available for trimethadione and caffeine
| Article | Year |
|---|---|
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Simplified test for determination of drug-oxidizing capacity in rats with chemical-induced liver injury using caffeine and trimethadione as model drugs.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Caffeine; Carbon Tetrachloride Poisoning; Galactosamine; Half-Life; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Trimethadione | 1992 |
A simplified approach for evaluation of hepatic drug-oxidizing activity with a simultaneous determination of caffeine and trimethadione and their demethylated metabolites in rats with a selective cytochrome P-450 inducer.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Humans; Liver; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione | 1992 |
Effect on pseudoconditioning of drugs with known central nervous activity.
Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione | 1974 |
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione | 1968 |
Comparison of hepatic drug-oxidizing activity after simultaneous administration of two probe drugs, caffeine and trimethadione, to human subjects.
Topics: Adult; Caffeine; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Half-Life; Humans; Liver; Male; Middle Aged; Oxidation-Reduction; Oxygenases; Theobromine; Theophylline; Trimethadione | 1993 |
Changes in the enzymatic activities of beagle liver during maturation as assessed both in vitro and in vivo.
Topics: Alanine Transaminase; Animals; Caffeine; Cytochrome P-450 Enzyme System; Dogs; Isoenzymes; Liver; Male; Oxidation-Reduction; Trimethadione | 1998 |