trimethadione has been researched along with antipyrine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (56.25) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jolivette, LJ; Ward, KW | 1 |
| Ebihara, A; Fujimura, A; Harada, K; Ohashi, K; Sakamoto, K; Sudo, T; Tanaka, E; Tateishi, T | 1 |
| Akita, H; Hamada, K; Iida, S; Kobayashi, S; Sakai, H; Tanaka, E; Uchida, E; Yasuhara, H | 1 |
| Kobayashi, S; Misawa, S; Tanaka, E; Yasuhara, H | 1 |
| Carlson, GP; Chadwick, RW | 1 |
| Nakamura, K; Tanaka, E | 2 |
| Ishikawa, A; Kuroiwa, Y; Misawa, S; Tanaka, E | 1 |
| Kohno, M; Kurata, N; Kuroiwa, Y; Tanaka, E; Yoshida, T | 1 |
| Kobayashi, S; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H | 1 |
| Aramphongphan, A; Kobayashi, S; Kurata, N; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H | 1 |
| Kobayashi, S; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H; Yoshida, T | 1 |
| Kinoshita, H; Kuroiwa, Y; Tanaka, E; Yoshida, T | 1 |
| Abe, K; Daling, Z; Horie, T; Nakamura, T; Tanaka, E | 1 |
| Tanaka, E; Yasuhara, H | 1 |
| Breimer, DD; Tanaka, E | 1 |
3 review(s) available for trimethadione and antipyrine
| Article | Year |
|---|---|
Comparability of in vitro and in vivo methods for the determination of alterations in drug metabolism.
Topics: Animals; Antipyrine; Hexachlorocyclohexane; Humans; In Vitro Techniques; Methods; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Trimethadione | 1987 |
[Evaluation of liver function in liver diseases using drugs as indicators].
Topics: Aminopyrine; Antipyrine; Erythromycin; Humans; Lidocaine; Liver; Liver Diseases; Liver Function Tests; Trimethadione | 1997 |
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Erythromycin; Humans; Liver Diseases; Liver Function Tests; Trimethadione | 1997 |
1 trial(s) available for trimethadione and antipyrine
| Article | Year |
|---|---|
The effect of roxatidine acetate and cimetidine on hepatic drug clearance assessed by simultaneous administration of three model substrates.
Topics: Adult; Antipyrine; Cimetidine; Half-Life; Histamine H2 Antagonists; Humans; Indocyanine Green; Liver; Male; Pharmaceutical Preparations; Piperidines; Trimethadione | 1989 |
12 other study(ies) available for trimethadione and antipyrine
| Article | Year |
|---|---|
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
The effect of diltiazem on hepatic drug oxidation assessed by antipyrine and trimethadione.
Topics: Adult; Antipyrine; Diltiazem; Half-Life; Humans; Liver; Male; Metabolic Clearance Rate; Premedication; Trimethadione | 1991 |
The effects of diltiazem on hepatic drug metabolizing enzymes in man using antipyrine, trimethadione and debrisoquine as model substrates.
Topics: Adult; Antipyrine; Debrisoquin; Diltiazem; Dimethadione; Drug Interactions; Half-Life; Humans; Liver; Male; Mixed Function Oxygenases; Trimethadione | 1991 |
Strain differences of antipyrine, trimethadione, and debrisoquine metabolism in female rats.
Topics: Analysis of Variance; Animals; Antipyrine; Debrisoquin; Female; Isoquinolines; Oxazoles; Rats; Rats, Inbred Strains; Species Specificity; Trimethadione | 1990 |
Comparison of trimethadione and antipyrine as indicators of oxidative drug metabolizing capacity in man.
Topics: Adult; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Drug Interactions; Half-Life; Humans; Male; Oxazoles; Trimethadione | 1989 |
Sex-related differences in hepatic drug-oxidizing capacity of streptozotocin-induced diabetic rats.
Topics: Animals; Antipyrine; Diabetes Mellitus, Experimental; Dimethadione; Female; Insulin; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sex Factors; Trimethadione | 1988 |
Induction of cytochrome P-450 and related drug-oxidizing activities in muscone (3-methylcyclopentadecanone)-treated rats.
Topics: 5-Aminolevulinate Synthetase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Antipyrine; Biotransformation; Cycloparaffins; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Trimethadione | 1987 |
The effects of short-term administration of ibuprofen on trimethadione metabolism and antipyrine metabolite formation in the rat.
Topics: Animals; Antipyrine; Ibuprofen; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione | 1985 |
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator.
Topics: Animals; Antipyrine; Half-Life; Indomethacin; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione | 1985 |
A method for estimation of hepatic drug-metabolizing capacity: determination of concentration of trimethadione and its metabolite in human serum.
Topics: Adult; Animals; Antipyrine; Dimethadione; Half-Life; Humans; Kinetics; Liver; Male; Middle Aged; Oxazoles; Rats; Trimethadione | 1984 |
Relationship between trimethadione metabolism and hepatic drug-oxidizing enzyme activities in different animal species.
Topics: Animals; Antipyrine; Cricetinae; Cytochrome P-450 Enzyme System; Dimethadione; Kinetics; Liver; Male; Mice; Oxazoles; Rabbits; Rats; Species Specificity; Trimethadione | 1983 |
Dual effects of a novel thienodiazepine platelet-activating factor antagonist, on drug-oxidizing enzymes in beagle dog.
Topics: Animals; Antipyrine; Azepines; Cytochrome P-450 Enzyme System; Dogs; Half-Life; Male; Metabolic Clearance Rate; Microsomes, Liver; Nitroanisole O-Demethylase; Oxidoreductases, N-Demethylating; Platelet Activating Factor; Regression Analysis; Triazoles; Trimethadione | 1994 |