Compounds > trimethadione
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trimethadione and 1-naphthylisothiocyanate

trimethadione has been researched along with 1-naphthylisothiocyanate in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ishikawa, A; Misawa, S; Tanaka, E1
Kinoshita, H; Kuroiwa, Y; Tanaka, E; Yoshida, T1
Kinoshita, H; Kuroiwa, Y; Takabatake, E; Tanaka, E; Yamamoto, T1

Other Studies

5 other study(ies) available for trimethadione and 1-naphthylisothiocyanate

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Simplified test for determination of drug-oxidizing capacity in rats with chemical-induced liver injury using caffeine and trimethadione as model drugs.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:3

    Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Caffeine; Carbon Tetrachloride Poisoning; Galactosamine; Half-Life; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Trimethadione

1992
Trimethadione as a model drug for the evaluation of hepatic drug-metabolizing capacity in normal and alpha-naphthylisothiocyanate-intoxicated rats.
    Pharmacology, 1982, Volume: 25, Issue:4

    Topics: 1-Naphthylisothiocyanate; Animals; Dose-Response Relationship, Drug; Kinetics; Liver; Male; Microsomes, Liver; Oxazoles; Rats; Rats, Inbred Strains; Thiocyanates; Trimethadione

1982
Pharmacokinetic studies of trimethadione and its metabolite in rats with chemical-induced liver injury.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:8

    Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Biotransformation; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dimethadione; Galactosamine; Injections, Intravenous; Kinetics; Male; Oxazoles; Rats; Time Factors; Trimethadione

1981