trimellitic anhydride has been researched along with dinitrochlorobenzene in 48 studies
*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]
*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.08) | 18.7374 |
1990's | 20 (41.67) | 18.2507 |
2000's | 22 (45.83) | 29.6817 |
2010's | 5 (10.42) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Basketter, DA; Cumberbatch, M; Dearman, RJ; Gould, SJ; Kimber, I; Peters, SW | 2 |
Dearman, RJ; Kimber, I | 3 |
Basketter, DA; Dearman, RJ; Kimber, I; Mitchell, JA | 1 |
Dearman, RJ; Hegarty, JM; Kimber, I | 1 |
Botham, PA; Hext, PM; Rattray, NJ; Walsh, ST; Woodcock, DR | 1 |
Potter, DW; Wederbrand, KS | 1 |
Blaikie, L; Botham, PA; Hartop, PJ; Hext, P; Morrow, T; Rattray, NJ; Wilson, AP; Woodcock, D | 1 |
Coleman, JW; Dearman, RJ; Holliday, MR; Kimber, I | 1 |
Arts, JH; Bloksma, N; Dröge, SC; Kuper, CF | 1 |
Basketter, DA; Dearman, RJ; Hilton, J; Kimber, I; Scholes, EW | 1 |
Dearman, RJ; Kemeny, DM; Kimber, I; Moussavi, A | 2 |
Arts, JH; Bloksma, N; Dröge, SC; Kuper, CF; Penninks, AH; Spanhaak, S | 1 |
Dearman, RJ; Gerberick, F; Kimber, I; Ryan, CA | 1 |
Basketter, DA; Dearman, RJ; Kimber, I | 1 |
Arts, JH; Bloksma, N; Kuper, CF; Spoor, SM | 1 |
Basketter, DA; Dearman, RJ; Evans, P; Kimber, I | 1 |
Basketter, DA; Dearman, RJ; Kimber, I; Warbrick, EV | 1 |
De Jong, WH; Fluitman, A; Garssen, J; Spiekstra, SW; Van Dijk, M; Van Loveren, H; Vandebriel, RJ | 1 |
de Jong, WH; Slob, W; van Loveren, H; van Och, FM; Vandebriel, RJ | 1 |
Daniel, KC; Dearman, RJ; Kemeny, DM; Kimber, I; Moussavi, A | 1 |
Ban, M; Hettich, D | 1 |
Ando, K; Hiramoto, K; Ikarashi, Y; Kikugawa, K; Kujirai, K; Mi, H | 1 |
Hayashi, M; Higashi, K; Kaneko, H; Kato, H | 1 |
Holsapple, MP; Ladics, GS; Loveless, SE; Plitnick, LM; Sailstad, DM; Selgrade, MJ; Smialowicz, RJ | 1 |
Dearman, RJ; Kimber, I; Skinner, R; Warbrick, EV | 1 |
De Jong, WH; Hendriks, JJ; Van Loveren, H; Vandebriel, RJ | 1 |
Farraj, AK; Harkema, JR; Kaminski, NE | 1 |
Dearman, RJ; Hopkins, JE; Humphreys, N; Kimber, I; Naisbitt, DJ; Park, BK | 1 |
Dearman, RJ; Humphreys, N; Kimber, I; Skinner, RA | 1 |
Ban, M; Goutet, M; Huguet, N; Langonné, I; Pépin, E | 2 |
Clelland, K; Cumberbatch, M; Dearman, RJ; Kimber, I | 1 |
De Vooght, V; Hoet, PH; Nemery, B; Tarkowski, M; Vanhooren, HM; Vanoirbeek, JA | 1 |
Basketter, DA; Bedford, PA; Holden, NJ; Ind, PW; Jowsey, IR; Knight, SC; Marks, NA; McCarthy, NE | 1 |
Fukuyama, T; Harada, T; Hayashi, K; Kosaka, T; Saito, TR; Shuto, Y; Tajima, Y; Ueda, H | 2 |
Betts, CJ; Caddick, HT; Dearman, RJ; Flanagan, BF; Kimber, I | 1 |
Braun, A; Dassow, C; Henjakovic, M; Hoymann, HG; Krug, N; Martin, C; Pohlmann, G; Ressmeyer, AR; Sewald, K; Uhlig, S | 1 |
Betts, CJ; Caddick, HT; Dearman, RJ; Kimber, I | 1 |
Jabłońska, E; Kur, B; Polakowska, E; Tarkowski, M | 1 |
Fukuyama, T; Hayashi, K; Kosaka, T; Tajima, Y; Ueda, H | 1 |
Chapman, VL; Dearman, RJ; Kimber, I; Moggs, J; Terranova, R; Zollinger, T | 1 |
Chapman, VL; Dearman, RJ; Kimber, I; Moggs, JG; Terranova, R | 1 |
Choi, WS; Choi, Y; Hong, KH; Kim, JH; Lee, WY; Park, C; Park, HJ; Song, H | 1 |
48 other study(ies) available for trimellitic anhydride and dinitrochlorobenzene
Article | Year |
---|---|
Influence of topical exposure to chemical allergens on murine Langerhans cells. Comparison of 2,4-dinitrochlorobenzene with trimellitic anhydride.
Topics: Administration, Topical; Allergens; Animals; Cell Count; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Flow Cytometry; Histocompatibility Antigens Class II; Langerhans Cells; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Skin | 1992 |
Langerhans cells, antigen presentation, and the diversity of responses to chemical allergens.
Topics: Allergens; Animals; Antigen-Presenting Cells; Dermatitis, Contact; Dinitrochlorobenzene; Drug Hypersensitivity; Hypersensitivity, Immediate; Langerhans Cells; Mice; Phthalic Anhydrides; Respiratory Hypersensitivity | 1992 |
The mechanisms and evaluation of chemically induced allergy.
Topics: Animals; Dinitrochlorobenzene; Drug Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Mice; Phthalic Anhydrides; T-Lymphocytes, Helper-Inducer | 1992 |
Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone.
Topics: Allergens; Animals; Antibodies; Antibody Formation; Dermatitis, Contact; Dinitrochlorobenzene; Female; Haptens; Immunoglobulin E; Immunoglobulin G; Immunoglobulin Isotypes; Mice; Mice, Inbred BALB C; Oxazolone; Phthalic Anhydrides; Respiratory Hypersensitivity | 1992 |
Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice.
Topics: Administration, Topical; Allergens; Animals; Dinitrochlorobenzene; Disease Models, Animal; Female; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunity, Cellular; Immunization, Passive; Immunoglobulin E; Injections, Intravenous; Mice; Mice, Inbred BALB C; Occupational Exposure; Phthalic Anhydrides; Time Factors; Vaccination | 1992 |
Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody.
Topics: Administration, Inhalation; Animals; Dinitrochlorobenzene; Disease Models, Animal; Drug Administration Schedule; Female; Haptens; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Respiratory Hypersensitivity | 1991 |
Differential stimulation of immune function by respiratory and contact chemical allergens.
Topics: Allergens; Animals; Cell Division; Dermatitis, Contact; Dinitrochlorobenzene; Female; Immunoglobulin G; Immunoglobulin Isotypes; Lymph Nodes; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Respiratory Hypersensitivity | 1991 |
The induction of respiratory allergy in guinea-pigs following intradermal injection of trimellitic anhydride: a comparison with the response to 2,4-dinitrochlorobenzene.
Topics: Administration, Inhalation; Animals; Antibody Formation; Dinitrochlorobenzene; Epitopes; Female; Guinea Pigs; Haptens; Immunization; Immunoglobulin E; Immunoglobulin G; Injections, Intradermal; Phthalic Acids; Phthalic Anhydrides; Respiratory Hypersensitivity | 1989 |
Total IgE antibody production in BALB/c mice after dermal exposure to chemicals.
Topics: Administration, Cutaneous; Aldehydes; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; Formaldehyde; Glutaral; Haptens; Immunization; Immunoglobulin E; Isocyanates; Mice; Mice, Inbred BALB C; Phthalic Anhydrides | 1995 |
A two-centre study for the evaluation and validation of an animal model for the assessment of the potential of small molecular weight chemicals to cause respiratory allergy.
Topics: Administration, Inhalation; Allergens; Animals; Antibody Specificity; Antigen-Antibody Complex; Dinitrochlorobenzene; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Haptens; Injections, Intradermal; Isocyanates; Male; Molecular Weight; Phthalic Anhydrides; Respiration; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate | 1995 |
Sensitization of mice to chemical allergens modulates the responsiveness of isolated mast cells to IgE-dependent activation.
Topics: Allergens; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Immunoglobulin E; Mast Cells; Mice; Mice, Inbred BALB C; Oxazolone; Phthalic Anhydrides; Serotonin | 1993 |
Local lymph node activation in rats after dermal application of the sensitizers 2,4-dinitrochlorobenzene and trimellitic anhydride.
Topics: Administration, Topical; Allergens; Animals; Antimetabolites; Bromodeoxyuridine; Cell Division; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Ear, External; Female; Irritants; Kidney; Liver; Lymph Nodes; Mice; Mice, Inbred BALB C; Organ Size; Phthalic Anhydrides; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar; Skin; Spleen | 1996 |
Experimental assessment of the sensitizing properties of formaldehyde.
Topics: Administration, Topical; Allergens; Animals; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Female; Formaldehyde; Guinea Pigs; Immunoglobulin E; Interferon-gamma; Interleukin-10; Irritants; Lymph Nodes; Mice; Mice, Inbred BALB C; Patch Tests; Phthalic Anhydrides | 1996 |
Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens.
Topics: Allergens; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Dinitrochlorobenzene; Female; Formaldehyde; Interferon-gamma; Interleukin-10; Interleukin-4; Isocyanates; Lung; Lymph Nodes; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Skin; T-Lymphocyte Subsets | 1996 |
Local lymph node activation and IgE responses in brown Norway and Wistar rats after dermal application of sensitizing and non-sensitizing chemicals.
Topics: Administration, Cutaneous; Allergens; Animals; Cell Count; Cell Division; Dermatitis, Contact; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Female; Formaldehyde; Immunoglobulin E; Lymph Nodes; Organ Size; Phthalic Anhydrides; Rats; Rats, Wistar; Salicylates; Skin Tests | 1997 |
Inducible interleukin 4 (IL-4) production and mRNA expression following exposure of mice to chemical allergens.
Topics: Allergens; Animals; Dinitrochlorobenzene; Environmental Exposure; Female; Interleukin-4; Irritants; Mice; Mice, Inbred BALB C; Mitogens; Phthalic Anhydrides; RNA, Messenger | 1998 |
Selective induction of type 2 cytokines following topical exposure of mice to platinum salts.
Topics: Administration, Topical; Allergens; Animals; Antineoplastic Agents; Cell Separation; Chlorides; Cisplatin; Cytokines; Dinitrochlorobenzene; Enzyme-Linked Immunosorbent Assay; Interferon-gamma; Interleukin-10; Interleukin-4; Irritants; Lymph Nodes; Lymphocyte Activation; Mice; Phthalic Anhydrides; Platinum Compounds; Radiation-Sensitizing Agents | 1998 |
Cytokine production by CD4+ and CD8+ T cells in mice following primary exposure to chemical allergens: evidence for functional differentiation of T lymphocytes in vivo.
Topics: Allergens; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Separation; Cytokines; Dinitrochlorobenzene; Female; Interferon-gamma; Interleukin-4; Lymph Nodes; Mice; Mice, Inbred BALB C; Mitogens; Phthalic Anhydrides; Time Factors | 1998 |
Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals.
Topics: Allergens; Animals; Body Weight; Bronchi; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Female; Immunoglobulin E; Organ Size; Phthalic Anhydrides; Rats; Rats, Inbred BN; Rats, Wistar; Respiratory Function Tests; Respiratory Hypersensitivity; Salicylates | 1998 |
Comparison of cytokine secretion profiles provoked in mice by glutaraldehyde and formaldehyde.
Topics: Administration, Topical; Allergens; Animals; Cell Division; Cytokines; Dinitrochlorobenzene; Disinfectants; Formaldehyde; Glutaral; Interferon-gamma; Interleukin-10; Interleukin-4; Irritants; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Phthalic Anhydrides | 1999 |
Analysis of interleukin 12 protein production and mRNA expression in mice exposed topically to chemical allergens.
Topics: Acetone; Administration, Topical; Allergens; Animals; Cells, Cultured; Dinitrochlorobenzene; DNA Primers; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Female; Interleukin-12; Lymph Nodes; Mice; Mice, Inbred BALB C; NADPH Oxidases; Olive Oil; Phthalic Anhydrides; Plant Oils; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-gamma and interleukin-4.
Topics: Allergens; Animals; Cells, Cultured; Dinitrochlorobenzene; Enzyme-Linked Immunosorbent Assay; Female; Interferon-gamma; Interleukin-4; Lymph Nodes; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Phthalic Anhydrides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate | 2000 |
A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins.
Topics: Allergens; Animals; Benzocaine; Benzothiazoles; Dermatitis, Contact; Diethylamines; Dinitrochlorobenzene; Dose-Response Relationship, Immunologic; Female; Linear Models; Lymph Nodes; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Oxazolone; Phthalic Anhydrides; Regression Analysis; Scintillation Counting; Specific Pathogen-Free Organisms; Thiazoles; Thiram; Toluene 2,4-Diisocyanate; Ziram | 2000 |
Antigen-specific and nonspecific determinants of cytokine production during topical sensitization of mice to chemical allergens.
Topics: Allergens; Animals; Antibodies; CD4-Positive T-Lymphocytes; CD40 Antigens; CD40 Ligand; Cytokines; Dendritic Cells; Dinitrochlorobenzene; Drug Interactions; Epitopes; Female; Immunization; Interferon-gamma; Interleukin-10; Interleukin-12; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Phthalic Anhydrides | 2000 |
Relationship between IgE positive cell numbers and serum total IgE levels in mice treated with trimellitic anhydride and dinitrochlorobenzene.
Topics: Aging; Allergens; Animals; Dinitrochlorobenzene; Dose-Response Relationship, Immunologic; Female; Hypersensitivity, Immediate; Immunoglobulin E; Irritants; Lymph Nodes; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Spleen; Trachea | 2001 |
Effect of food reductones, 2,5-dimethyl-4-hydroxy-3(2H)-furanone (DMHF) and hydroxyhydroquinone (HHQ), on lipid peroxidation and type IV and I allergy responses of mouse.
Topics: Animals; Coffee; Dermatitis, Contact; Diet; Dinitrochlorobenzene; Food Analysis; Furans; Glycine max; Hydroquinones; Immunoglobulin E; Lipid Peroxidation; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Nitrogen Dioxide; Phthalic Anhydrides; Respiratory Hypersensitivity; Thiobarbituric Acid Reactive Substances | 2001 |
Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c.
Topics: Allergens; Animals; Dinitrochlorobenzene; Dinitrofluorobenzene; DNA Primers; Interleukin-12; Interleukin-4; Isocyanates; Local Lymph Node Assay; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Weight; Oxazoles; Phthalic Anhydrides; Picryl Chloride; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate | 2001 |
Cytokine profiling for chemical sensitizers: application of the ribonuclease protection assay and effect of dose.
Topics: Allergens; Animals; Asthma; Cytokines; Dinitrochlorobenzene; Dose-Response Relationship, Immunologic; Female; Hypersensitivity; Lymph Nodes; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; RNA, Messenger; T-Lymphocytes, Helper-Inducer | 2002 |
Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses.
Topics: Allergens; Animals; Cytokines; Dermatitis, Contact; Dinitrochlorobenzene; Immunoglobulin E; Irritants; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Random Allocation; Rats; Rats, Inbred BN; Respiratory Tract Diseases; Species Specificity; Th1 Cells; Th2 Cells | 2002 |
Impact of exposure duration by low molecular weight compounds on interferon-gamma and interleukin-4 mRNA expression and production in the draining lymph nodes of mice.
Topics: Allergens; Animals; Concanavalin A; Dinitrochlorobenzene; Enzyme-Linked Immunosorbent Assay; Female; Hypersensitivity; Interferon-gamma; Interleukin-4; Local Lymph Node Assay; Lymph Nodes; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice.
Topics: Administration, Intranasal; Allergens; Animals; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Dinitrochlorobenzene; Immunization; Immunoglobulin E; Lung; Male; Mice; Mice, Inbred Strains; Nasal Mucosa; Oxazolone; Phthalic Anhydrides; Rhinitis, Allergic, Perennial; RNA, Messenger; Th1 Cells; Th2 Cells | 2004 |
Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells.
Topics: Animals; Anti-Infective Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Dinitrochlorobenzene; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Interleukin-5; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Nitroso Compounds; Phthalic Anhydrides; Sulfamethoxazole; Th1 Cells; Th2 Cells | 2005 |
Allergen-induced cytokine phenotypes in mice: role of CD4 and CD8 T cell populations.
Topics: Allergens; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Dinitrochlorobenzene; Female; Fluorescein-5-isothiocyanate; Formaldehyde; Interferon-gamma; Interleukin-4; Lymphocyte Count; Mice; Mice, Inbred BALB C; Phenotype; Phthalic Anhydrides; Respiratory Hypersensitivity | 2005 |
Identification of contact and respiratory sensitizers using flow cytometry.
Topics: Administration, Inhalation; Administration, Topical; Allergens; Animals; Cytokines; Dinitrochlorobenzene; Female; Flow Cytometry; Histocompatibility Antigens Class II; Immunoglobulin E; Local Lymph Node Assay; Lymph Nodes; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Receptors, Interleukin-4; Time Factors | 2005 |
Impact of cutaneous IL-10 on resident epidermal Langerhans' cells and the development of polarized immune responses.
Topics: Administration, Topical; Allergens; Animals; Cell Movement; Cytokines; Dinitrochlorobenzene; Interleukin-10; Irritants; Kinetics; Langerhans Cells; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Skin; Th1 Cells; Th2 Cells | 2005 |
Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer.
Topics: Allergens; Animals; Asthma; Cytokines; Dinitrochlorobenzene; Disease Models, Animal; Immunoglobulin E; Immunoglobulin G; Irritants; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Respiratory Function Tests; Th1 Cells; Th2 Cells | 2006 |
Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity.
Topics: Adult; Aged; Cell Proliferation; Dendritic Cells; Dinitrochlorobenzene; Female; Haptens; Humans; Hypersensitivity, Immediate; Interferon-gamma; Interleukin-12; Interleukin-13; Irritants; Lymphocyte Activation; Male; Middle Aged; Phthalic Anhydrides; T-Lymphocytes | 2008 |
Detection of low-level environmental chemical allergy by a long-term sensitization method.
Topics: Allergens; Animals; B-Lymphocytes; Cytokines; Dinitrochlorobenzene; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunization; Immunoglobulin E; Local Lymph Node Assay; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred BALB C; Multiple Chemical Sensitivity; Phthalic Anhydrides; Toluene 2,4-Diisocyanate | 2008 |
Cytokine profiling of chemical allergens in mice: measurement of message versus protein.
Topics: Allergens; Animals; Cytokines; Dinitrochlorobenzene; Female; Kinetics; Lymph Nodes; Mice; Mice, Inbred BALB C; Nuclease Protection Assays; Oligonucleotide Array Sequence Analysis; Phthalic Anhydrides; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction | 2008 |
Use of long term dermal sensitization followed by intratracheal challenge method to identify low-dose chemical-induced respiratory allergic responses in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Dose-Response Relationship, Immunologic; Environmental Pollutants; Female; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Trachea | 2008 |
Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies.
Topics: Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; In Vitro Techniques; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Pneumonia; Respiratory Function Tests | 2008 |
Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response.
Topics: Allergens; Animals; Cell Proliferation; Cell Separation; Cell Survival; Cells, Cultured; Coloring Agents; Cytokines; Dinitrochlorobenzene; Female; Lymph Nodes; Mice; Mice, Inbred BALB C; Mitogens; Phthalic Anhydrides; Sensitivity and Specificity; Time Factors; Toxicity Tests, Acute; Toxicity Tests, Chronic; Trypan Blue | 2009 |
Comparative studies of lymph node cell subpopulations and cytokine expression in murine model for testing the potentials of chemicals to induce respiratory sensitization.
Topics: Allergens; Animals; Bronchial Provocation Tests; Cytokines; Dinitrochlorobenzene; Disease Models, Animal; Inflammation; Interferon-gamma; Interleukin-4; Irritants; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Respiratory Hypersensitivity; RNA, Messenger; Toluene 2,4-Diisocyanate | 2008 |
Prior exposure to immunosuppressive organophosphorus or organochlorine compounds aggravates the T(H)1- and T(H)2-type allergy caused by topical sensitization to 2,4-dinitrochlorobenzene and trimellitic anhydride.
Topics: Animals; Cell Proliferation; Dinitrochlorobenzene; Drug Hypersensitivity; Female; Humans; Insecticides; Irritants; Jurkat Cells; Methoxychlor; Mice; Mice, Inbred BALB C; Parathion; Phthalic Anhydrides; Th1 Cells; Th2 Cells | 2011 |
Identification of contact and respiratory sensitizers according to IL-4 receptor α expression and IL-2 production.
Topics: Allergens; Animals; Dinitrochlorobenzene; Female; Flow Cytometry; Hypersensitivity; Immunoglobulin E; Interleukin-2; Local Lymph Node Assay; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Receptors, Cell Surface; Statistics, Nonparametric | 2012 |
Chemical allergen induced perturbations of the mouse lymph node DNA methylome.
Topics: Allergens; Animals; Dinitrochlorobenzene; DNA; DNA Methylation; Epigenesis, Genetic; Female; Genome-Wide Association Study; Immunoprecipitation; Lymph Nodes; Mice, Inbred BALB C; Phthalic Anhydrides; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction | 2014 |
Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens.
Topics: 5-Methylcytosine; Allergens; Animals; Cytosine; Dinitrochlorobenzene; DNA Fragmentation; DNA Methylation; Epigenesis, Genetic; Female; Immunoprecipitation; Local Lymph Node Assay; Lymph Nodes; Mice, Inbred BALB C; Phthalic Anhydrides; Polymerase Chain Reaction; Promoter Regions, Genetic | 2016 |
A novel mouse model of atopic dermatitis that is T helper 2 (Th2)-polarized by an epicutaneous allergen.
Topics: Allergens; Animals; Dermatitis, Atopic; Detergents; Dinitrochlorobenzene; Disease Models, Animal; Female; Formaldehyde; Immunoglobulin E; Interferon-gamma; Interleukin-4; Isocyanates; Mast Cells; Mice, Inbred BALB C; Phthalic Anhydrides; Pyroglyphidae; Skin; Th2 Cells; Toluene; Toluene 2,4-Diisocyanate | 2018 |