trilostane has been researched along with pregnenolone in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (32.35) | 18.7374 |
| 1990's | 10 (29.41) | 18.2507 |
| 2000's | 9 (26.47) | 29.6817 |
| 2010's | 3 (8.82) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Creange, JE; Hardomg, HR; Potts, GO; Schane, HP | 1 |
| Benahmed, M; Chauvin, MA; de Peretti, E; Mauduit, C; Morera, AM | 1 |
| Bernier, M; Darbeida, H; Durand, P; Penhoat, A; Saez, JM | 1 |
| Lin, YW; Petrino, TR; Wallace, RA | 1 |
| Nowotny, P; Vierhapper, H; Waldhäusl, W | 1 |
| Hamamoto, I; Hiwatashi, A; Ichikawa, Y | 1 |
| Corcelle-Cerf, F; Kolanowski, J; Lambert, F; Lammerant, J | 1 |
| Kolanowski, J; Lambert, F; Lammerant, J | 1 |
| Jacobs, HS; James, VH; Jones, DL; Paintin, DB; Piura, B; van der Spuy, ZM; Wright, CS | 1 |
| Mitchell, BF; Powell, WA | 1 |
| Boyd, GS; Shears, SB | 1 |
| Lemon, M; Mauléon, P | 1 |
| Baulieu, EE; Corpéchot, C; Haug, M; Mayo, W; Perché, F; Robel, P; Simon, H; Young, J | 1 |
| Akwa, Y; Baulieu, EE; Ferzaz, B; Guennoun, R; Jung-Testas, I; Koenig, HL; Ressouches, A; Robel, P; Schumacher, M; Thi, AN | 1 |
| Duffy, DM; Hess, DL; Stouffer, RL | 1 |
| Higuchi, K; Kominami, S; Takemori, S; Yamazaki, T | 1 |
| Baulieu, EE; Corpéchot, C; Eychenne, B; Haug, M; Perché, F; Robel, P; Young, J | 1 |
| Holtan, DW; Kerby, JL; Schutzer, WE | 1 |
| Givalois, L; Li, S; Pelletier, G | 1 |
| Garcia de Yebenes, E; Li, S; Pelletier, G | 1 |
| Furster, C | 1 |
| Bhattacharyya, S; Bhattacharyya, SP; Mukherjee, D; Sen, U | 1 |
| Chang, LL; Ho, LT; Kau, MM; Wang, PS; Wun, WS | 1 |
| Chiao, YC; Cho, WL; Wang, PS | 1 |
| Coirini, H; Delespierre, B; Gouézou, M; Guennoun, R; Schumacher, M | 1 |
| Chang, LL; Ho, LL; Wang, PS; Wun, WS | 1 |
| Lin, CS; Lu, CC; Tsai, SC; Wang, PS | 1 |
| Debonnel, G; Robichaud, M | 1 |
| Chang, LL; Chiang, W; Hsia, SM; Hung, CT; Wang, PS; Wun, AW | 1 |
| Dubnau, E; Sampson, NS; Smith, I; Yang, X | 1 |
| Chang, LL; Wang, PS; Wun, WS | 1 |
| Lepschy, M; Möstl, E; Ouschan, C; Zeugswetter, F | 1 |
| Schreiber, NB; Spicer, LJ | 1 |
| Biagini, G; Costa, AM; Lucchi, C; Messina, S; Rustichelli, C; Senn, L | 1 |
1 review(s) available for trilostane and pregnenolone
| Article | Year |
|---|---|
Biosynthesis and assay of neurosteroids in rats and mice: functional correlates.
Topics: Adrenalectomy; Aggression; Aging; Animals; Behavior, Animal; Dehydroepiandrosterone; Dihydrotestosterone; Female; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Lactation; Male; Memory; Mice; Orchiectomy; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1995 |
33 other study(ies) available for trilostane and pregnenolone
| Article | Year |
|---|---|
Trilostane, an orally active inhibitor of steroid biosynthesis.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Androstanes; Animals; Corticosterone; Dihydrotestosterone; Female; In Vitro Techniques; Male; Microsomes; Nitriles; Organ Size; Pregnenolone; Progesterone; Rats | 1978 |
Effect of activin A on dehydroepiandrosterone and testosterone secretion by primary immature porcine Leydig cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Activins; Animals; Cells, Cultured; Chorionic Gonadotropin; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dihydrotestosterone; Hydroxycholesterols; Inhibins; Leydig Cells; Male; Pregnenolone; Swine; Testosterone | 1991 |
Inhibition of hormonal-induced cAMP and steroid production by inhibitors of pregnenolone metabolism in adrenal and Leydig cells.
Topics: Adrenal Glands; Animals; Carrier Proteins; Cattle; Cells, Cultured; Cholesterol; Colforsin; Cyclic AMP; Dihydrotestosterone; Endoribonucleases; Intracellular Signaling Peptides and Proteins; Leydig Cells; Male; Phosphoprotein Phosphatases; Pregnenolone; Proteins; RNA-Binding Proteins; Sheep; Spironolactone; Steroids; Swine; Tetrahydronaphthalenes | 1988 |
Steroidogenesis in Fundulus heteroclitus. I. Production of 17 alpha-hydroxy,20 beta-dihydroprogesterone, testosterone, and 17 beta-estradiol by prematurational follicles in vitro.
Topics: 20-alpha-Dihydroprogesterone; Aminoglutethimide; Animals; Culture; Cyprinodontiformes; Dihydrotestosterone; Estradiol; Female; Hydroxycholesterols; Killifishes; Ovarian Follicle; Pregnenolone; Progesterone; Radioimmunoassay; Testosterone | 1989 |
Effect of trilostan on steroid excretion in man: compensated inhibition of 3 beta-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Androstenediol; Chromatography, Gas; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Glucocorticoids; Humans; Hydrocortisone; Male; Pregnenolone; Renin; Steroids | 1986 |
Purification and kinetic properties of 3 beta-hydroxysteroid dehydrogenase from bovine adrenocortical microsomes.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Animals; Binding Sites; Binding, Competitive; Cattle; Dihydrotestosterone; Electrophoresis, Polyacrylamide Gel; Isoelectric Point; Kinetics; Microsomes; Molecular Weight; NAD; NADP; Pregnenolone | 1985 |
On the specificity of the inhibitory effect of trilostane and aminoglutethimide on adrenocortical steroidogenesis in guinea pig.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cortodoxone; Dihydrotestosterone; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Male; Pregnenolone; Progesterone | 1984 |
The enhancement of pregnenolone production as the main mechanism of the prolonged stimulatory effect of ACTH on cortisol production by guinea-pig adrenocortical cells.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Dihydrotestosterone; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Male; Pregnenolone; Time Factors | 1984 |
Inhibition of 3-beta-hydroxy steroid dehydrogenase activity in first trimester human pregnancy with trilostane and WIN 32729.
Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents; Abortifacient Agents, Steroidal; Dehydroepiandrosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Pregnancy; Pregnancy Trimester, First; Pregnenolone; Progesterone | 1983 |
Progesterone production by human fetal membranes: an in vitro incubation system for studying hormone production and metabolism.
Topics: 3-Hydroxysteroid Dehydrogenases; Amnion; Chorion; Decidua; Dihydrotestosterone; Extraembryonic Membranes; Female; Humans; In Vitro Techniques; Pregnancy; Pregnenolone; Progesterone; Radioimmunoassay | 1984 |
The effect of azastene, cyanoketone and trilostane upon respiration and cleavage of the cholesterol side chain in mitochondria from bovine adrenal cortex.
Topics: Adrenal Cortex; Androstanols; Androstenols; Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Cyanoketone; Dihydrotestosterone; Kinetics; Mitochondria; Nitriles; Oxidative Phosphorylation; Oxidoreductases; Oxygen Consumption; Pregnenolone | 1981 |
Interaction between two luteal cell types from the corpus luteum of the sow in progesterone synthesis in vitro.
Topics: Abortifacient Agents, Steroidal; Aminoglutethimide; Animals; Cells, Cultured; Cholesterol; Corpus Luteum; Dihydrotestosterone; Female; Luteal Cells; Perfusion; Pregnancy; Pregnenolone; Progesterone; Swine | 1982 |
Progesterone synthesis and myelin formation by Schwann cells.
Topics: Animals; Axons; Cells, Cultured; Dihydrotestosterone; Ganglia, Spinal; Male; Mice; Mifepristone; Myelin Sheath; Nerve Regeneration; Pregnenolone; Progesterone; Schwann Cells; Sciatic Nerve | 1995 |
Acute administration of a 3 beta-hydroxysteroid dehydrogenase inhibitor to rhesus monkeys at the midluteal phase of the menstrual cycle: evidence for possible autocrine regulation of the primate corpus luteum by progesterone.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cell Nucleus; Corpus Luteum; Dihydrotestosterone; Female; Hydrocortisone; Kinetics; Luteal Phase; Luteinizing Hormone; Macaca mulatta; Pregnenolone; Progesterone; Receptors, Progesterone | 1994 |
15-lipoxygenase metabolite(s) of arachidonic acid mediates adrenocorticotropin action in bovine adrenal steroidogenesis.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acids; Benzoquinones; Bucladesine; Cattle; Cells, Cultured; Cosyntropin; Cyclic AMP; Dihydrotestosterone; Enzyme Inhibitors; Indomethacin; Isoquinolines; Kinetics; Leukotrienes; Lipid Peroxides; Lipoxygenase Inhibitors; Masoprocol; Pregnenolone; Sulfonamides; Tetrahydronaphthalenes; Zona Fasciculata; Zona Reticularis | 1996 |
Neurosteroids in the mouse brain: behavioral and pharmacological effects of a 3 beta-hydroxysteroid dehydrogenase inhibitor.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Brain; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Humans; Mice; Pregnanolone; Pregnenolone; Progesterone; Sexual Behavior, Animal | 1996 |
Differential effect of trilostane on the progestin milieu in the pregnant mare.
Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Animals; Dihydrotestosterone; Female; Horses; Male; Placenta; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Progestins | 1996 |
Involvement of neurosteroids in the effect of the endogenous benzodiazepine receptor ligand octadecaneuropeptide (ODN) on gonadotropin-releasing hormone gene expression in rat brain.
Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha Reductase Inhibitors; Adrenalectomy; Animals; Diazepam Binding Inhibitor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Gene Expression; Gonadotropin-Releasing Hormone; Male; Neuropeptides; Orchiectomy; Peptide Fragments; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley | 1997 |
Regulation of proopiomelanocortin gene expression by endogenous ligands of the GABAA receptor complex as evaluated by in situ hybridization in the rat pars intermedia.
Topics: Adrenalectomy; Animals; Carrier Proteins; Cerebral Ventricles; Diazepam Binding Inhibitor; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; GABA Agonists; In Situ Hybridization; Injections, Intravenous; Injections, Intraventricular; Male; Neurons; Neuropeptides; Orchiectomy; Peptide Fragments; Pituitary Gland; Pregnenolone; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Transcription, Genetic | 1997 |
Hepatic and extrahepatic dehydrogenation/isomerization of 5-cholestene-3 beta,7 alpha-diol: localization of 3 beta-hydroxy-delta 5-C27-steroid dehydrogenase in pig tissues and subcellular fractions.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Antibodies, Monoclonal; Bile Acids and Salts; Bile Ducts; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Hydroxycholesterols; Immunohistochemistry; Liver; Male; Microsomes; Microsomes, Liver; Pregnenolone; Subcellular Fractions; Swine; Tissue Distribution | 1999 |
Identification of maturation-inducing steroid in a freshwater perch Anabas testudineus and differential responses of intact follicles and denuded oocytes to cyclic AMP in oocyte maturation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dihydrotestosterone; Female; Hydroxyprogesterones; Oocytes; Organ Culture Techniques; Ovarian Follicle; Perches; Pregnenolone | 2000 |
Effects of fasting on corticosterone production by zona fasciculata-reticularis cells in ovariectomized rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adrenocorticotropic Hormone; Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corticosterone; Culture Media, Conditioned; Dihydrotestosterone; Female; Food Deprivation; Nifedipine; Ovariectomy; Phenanthridines; Phosphoproteins; Pregnenolone; Rats; Rats, Sprague-Dawley; Zona Fasciculata; Zona Reticularis | 2002 |
Inhibition of testosterone production by propylthiouracil in rat Leydig cells.
Topics: Animals; Antimetabolites; Blotting, Western; Cell Separation; Cholesterol Side-Chain Cleavage Enzyme; Depression, Chemical; Dihydrotestosterone; Hydroxycholesterols; Leydig Cells; Male; Phosphoproteins; Pregnenolone; Propylthiouracil; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; Testosterone | 2002 |
3 beta-hydroxysteroid dehydrogenase isomerase (3beta-HSD) activity in the rat sciatic nerve: kinetic analysis and regulation by steroids.
Topics: Animals; Blotting, Western; Chromatography, Thin Layer; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Gas Chromatography-Mass Spectrometry; Kinetics; Male; Multienzyme Complexes; Pregnenolone; Progesterone; Progesterone Reductase; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Steroid Isomerases | 2003 |
Effects of dehydroepiandrosterone on corticosterone release in rat zona fasciculata-reticularis cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cyclic AMP; Dehydroepiandrosterone; Desoxycorticosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Gene Expression; Hydroxycholesterols; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 11-beta-Hydroxylase; Zona Fasciculata; Zona Reticularis | 2003 |
Antisteroidogenic actions of hydrogen peroxide on rat Leydig cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstenedione; Animals; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Hydroxycholesterols; Leydig Cells; Male; Oxidants; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Spermatozoa; Testosterone | 2003 |
Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids.
Topics: 5-alpha-Dihydroprogesterone; Animals; Anisoles; Antipsychotic Agents; Dehydroepiandrosterone; Dihydrotestosterone; Female; Finasteride; Gender Identity; Gonadal Steroid Hormones; Neurons; Ovariectomy; Pregnenolone; Progesterone; Propylamines; Protein Isoforms; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Synaptic Transmission; Time Factors | 2004 |
Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells.
Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Acetone; Adrenocorticotropic Hormone; Animals; Coix; Colforsin; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Hydroxycholesterols; Phosphoproteins; Plant Extracts; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Zona Fasciculata; Zona Reticularis | 2006 |
Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Bacterial Proteins; Catalysis; Cholesterol; Computational Biology; Dehydroepiandrosterone; Detergents; Dihydrotestosterone; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Mutation; Mycobacterium tuberculosis; NAD; Osmolar Concentration; Phylogeny; Pregnenolone; Recombinant Proteins; Sterols; Substrate Specificity | 2007 |
Effects of nonylphenol on aldosterone release from rat zona glomerulosa cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Angiotensin II; Animals; Calcium; Cells, Cultured; Corticosterone; Cytochrome P-450 CYP11B2; Dihydrotestosterone; Hydroxycholesterols; Indoles; Male; Phenols; Phosphoproteins; Potassium; Pregnenolone; Rats; Rats, Sprague-Dawley; Water Pollutants, Chemical; Zona Glomerulosa | 2012 |
The influence of trilostane on steroid hormone metabolism in canine adrenal glands and corpora lutea-an in vitro study.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Animals; Autoradiography; Corpus Luteum; Dehydroepiandrosterone; Dihydrotestosterone; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Pregnenolone | 2012 |
Effects of fibroblast growth factor 9 (FGF9) on steroidogenesis and gene expression and control of FGF9 mRNA in bovine granulosa cells.
Topics: Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Dihydrotestosterone; Female; Fibroblast Growth Factor 9; Granulosa Cells; Phosphoproteins; Pregnenolone; Receptors, FSH | 2012 |
Augmentation of endogenous neurosteroid synthesis alters experimental status epilepticus dynamics.
Topics: 5-alpha-Dihydroprogesterone; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Electrocorticography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neocortex; Neurosteroids; Pregnanolone; Pregnenolone; Progesterone; Rats; Receptors, GABA-A; Status Epilepticus; Tandem Mass Spectrometry; Time Factors | 2020 |