triiodothyronine has been researched along with phenobarbital in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (52.86) | 18.7374 |
| 1990's | 15 (21.43) | 18.2507 |
| 2000's | 11 (15.71) | 29.6817 |
| 2010's | 7 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ganes, T; Johannessen, SI; Rootwelt, K | 1 |
| Bouhnik, J; Michel, R; Naltchayan, S; Négrié, C | 1 |
| Bates, D; Evered, DC; Heath, A; Howe, JG; Ratcliffe, WA; Schardt, CW; Yeo, PP | 1 |
| Marselos, M; Puhakainen, E; Rantanen, T | 1 |
| Hüfner, M; Knöpfle, M | 1 |
| Barth, A | 1 |
| Catinot, R; Cordier, A; de Sandro, V; Kriszt, W; Richert, L | 1 |
| Bräunlich, H; Fleck, C; Kabath, P; Linstedt, A; Linstedt, U; Scharke, U | 1 |
| Boddaert, A; Chevrier, M; Cordier, A; De Sandro, V; Melcion, C; Richert, L | 1 |
| Bräunlich, H; Fleck, C | 1 |
| Nugon-Baudon, L; Rabot, S; Raibaud, P; Szylit, O | 1 |
| Fandrey, J; Jelkmann, W; Seydel, FP; Siegers, CP | 1 |
| Zbinden, G | 1 |
| Catto, L; Jones, RB; Leonard, T; Poole, A; Pritchard, D | 1 |
| Bräunlich, H; Fleck, C; Nguyen Trong, T | 1 |
| Escousse, A; Goudonnet, H; Mounié, J; Serrar, M; Truchot, RC | 1 |
| Kodama, S; Komatsu, M; Konishi, H; Matsuo, T; Momota, K; Tanaka, K; Yokoyama, S | 1 |
| Weissel, M | 1 |
| Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC | 1 |
| Kaciński, M; Stopyrowa, J; Szafran, Z; Sztefko, K | 1 |
| Boccuzzi, G; Guglielmone, R; Ugazio, G | 1 |
| Domingo, J; Estadella, MD; Pujol, MJ | 1 |
| Gupta, MP; Khanduja, KL; Koul, A; Koul, IB; Pathak, CM; Sharma, RR; Vaidyanathan, S | 1 |
| Gelman, S | 1 |
| Greiling, H; Greiling, K; Klinger, W; Müller, D | 1 |
| Withers, BT | 1 |
| Gerdes, H; Joseph, K; Littmann, KP; Mahlstedt, J | 1 |
| Oppenheimer, JH | 1 |
| Deb, C; Hanker, JS; Morizono, Y; Seligman, AM; Zenker, N | 1 |
| Kozyreff, V; Oppenheimer, JH; Surks, MI | 1 |
| Myant, NB | 1 |
| Ericsson, JL; Ernster, L; Orrenius, S | 1 |
| Selye, H | 1 |
| Becker, CE; Cavlieri, RR; Sung, LC | 1 |
| Bohner, J; Kallee, E; Mallet, D; Secker, KH; Wahl, R | 1 |
| Oppenheimer, JH; Schwartz, HL; Surks, MI | 2 |
| Crigler, JF | 1 |
| Bernstein, G; Oppenheimer, JH; Schwartz, HL; Shapiro, HC; Surks, MI | 1 |
| Crigler, JF; Gold, NI | 1 |
| Kozyreff, V; Oppenheimer, JH; Schwartz, HL; Surks, MI | 1 |
| Becker, BA; Harbison, RD | 1 |
| Bollati, A; Caminiti, A; Focarile, F; Grasso, E; Rondanini, GF; Zanini, R | 1 |
| Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M | 1 |
| Johnson, S; McKillop, D; Miller, J; Smith, IK | 1 |
| Drummond, GS; Rosenberg, DW; Smith, TJ | 1 |
| Ganem, LG; Ikegwuonu, FI; Jefcoate, CR; Larson, MC; Shen, X | 1 |
| Grüters, A; Hüfner, M; Lakomek, M; Roth, C; Siggelkow, H | 1 |
| Bergman, A; Brouwer, A; Legger, FF; Moonen, MJ; Schuur, AG; van Leeuwen-Bol, I; van Meeteren, ME; Visser, TJ | 1 |
| Kantrowitz, LB; Melián, C; Nichols, R; Peterson, ME; Trepanier, LA | 1 |
| Hashmi, R; Hood, A; Klaassen, CD | 1 |
| Castro-Gago, M; Del Río-Garma, M; Del Río-Garma, MC; Eirís-Puñal, J; Lojo-Rocamonde, S; Novo-Rodríguez, I | 1 |
| Hood, A; Klaassen, CD | 1 |
| Kajimura, T; Nomura, M; Ohno, H; Satoh, H; Sugawara, T; Tsuchiya, Y | 1 |
| Inoue, Y; Kurata, Y; Makinodan, F; Tanaka, K; Wako, Y | 1 |
| Hirose, M; Ikeda, T; Imazawa, T; Kimura, S; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY | 1 |
| Kawamura, S; Kunimatsu, T; Mikami, N; Miyata, K; Okuno, Y; Seki, T; Sukata, T; Yabushita, S; Yamada, T | 1 |
| Moore, DD; Qatanani, M; Zhang, J | 1 |
| Degawa, M; Ikushiro, S; Kato, Y; Suzuki, H; Yamada, S | 1 |
| Matsui, K; Moore, R; Negishi, M; Tien, ES | 1 |
| Coelho-Palermo Cunha, G; van Ravenzwaay, B | 1 |
| Andres, J; Bode, LM; Carnevali, LC; Hirsch-Ernst, KI; Kuna, M; Neuschäfer-Rube, F; Püschel, GP; Wieneke, N | 1 |
| Degawa, M; Haraguchi, K; Ikushiro, S; Ito, Y; Kato, Y; Suzuki, H; Uchida, S; Yamada, S | 1 |
| de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE | 1 |
| Ishiguro, T; Kawakami, Y; Kumazawa, T; Li, Y; Matsumoto, Y; Nishitani, H; Tagawa, Y | 1 |
5 review(s) available for triiodothyronine and phenobarbital
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Modification of peripheral thyroid hormone metabolism by drugs].
Topics: Amiodarone; Antipyrine; Dexamethasone; Heparin; Humans; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Rifampin; Thiouracil; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1988 |
Interaction of drugs with thyroid hormone binding sites.
Topics: Binding Sites; Blood Proteins; Cell Nucleus; Drug Interactions; Endoplasmic Reticulum; Graves Disease; Humans; Kinetics; Liver; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1973 |
Effects of drugs on the metabolism of bile acids.
Topics: Animals; Bile Acids and Salts; Biological Transport; Biological Transport, Active; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol; Cholestyramine Resin; Cholic Acids; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Humans; Hydroxycholesterols; Ileum; Intestinal Mucosa; Liver; Liver Circulation; Mixed Function Oxygenases; Phenobarbital; Propylthiouracil; Rats; Sulfathiazoles; Taurine; Thyroid Gland; Thyroxine; Triiodothyronine; Vitamins | 1972 |
65 other study(ies) available for triiodothyronine and phenobarbital
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans.
Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Triiodothyronine, Reverse | 1978 |
Comparative effects of dexamethasone and phenobarbital on adrenal cortex, liver cytochrome P450 contents and serum thyroid hormones.
Topics: Adrenal Cortex; Animals; Cytochrome P-450 Enzyme System; Dexamethasone; Male; Microsomes; Microsomes, Liver; Mitochondria; Molecular Weight; Phenobarbital; Proteins; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1979 |
Anticonvulsants and thyroid function.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1978 |
The hepatic glucuronate pathway in the rat after treatment with 3,3',5-triiodothyronine and phenobarbital.
Topics: Animals; Glucuronates; Glucuronidase; Glucuronosyltransferase; Hyperthyroidism; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Triiodothyronine; Uridine Diphosphate Glucose Dehydrogenase | 1976 |
Pharmacological influences on T4 to T3 conversion in rat liver.
Topics: Animals; Dexamethasone; Kinetics; Liver; Phenobarbital; Phenytoin; Rats; Thyroxine; Triiodothyronine | 1976 |
Influence of phenobarbital and triiodothyronine on the development of hepatic eosine transport in rats.
Topics: Animals; Biological Transport; Eosine Yellowish-(YS); Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Triiodothyronine | 1992 |
Male rat hepatic UDP-glucuronosyltransferase activity toward thyroxine. Activation and induction properties--relation with thyroxine plasma disappearance rate.
Topics: Animals; Detergents; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Thyrotropin; Thyroxine; Triiodothyronine | 1992 |
Relation between renal and hepatic excretion of drugs. XIV. Elimination of ioglycamic acid after nephrectomy, bile duct ligation, and after treatment with hormones or xenobiotics in young and adult rats.
Topics: Animals; Bile Ducts; Cyclopenthiazide; Dexamethasone; Female; Ioglycamic Acid; Kidney; Ligation; Liver; Nephrectomy; Phenobarbital; Rats; Rats, Inbred Strains; Triiodothyronine | 1991 |
Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbital, and 3-methylcholanthrene on hepatic and renal T4 metabolism and thyroid gland function in rats.
Topics: Amiodarone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes b5; Glucuronosyltransferase; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxygenases; Phenobarbital; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
Age dependent differences in stimulation and compensation of renal and biliary transport processes. Correlation to the physicochemical properties of the exerted substances.
Topics: Aging; Animals; Bile; Biological Transport, Active; Chemical Phenomena; Chemistry, Physical; Coloring Agents; Cyclopenthiazide; Dexamethasone; Female; Kidney; Liver Function Tests; Phenobarbital; Rats; Rats, Inbred Strains; Triiodothyronine; Tromethamine | 1990 |
Glucosinolates toxicity in growing rats: interactions with the hepatic detoxification system.
Topics: Animals; Brassica; Cytochrome P-450 Enzyme System; Diet; Eating; Glucosinolates; Glucuronosyltransferase; Glutathione Transferase; Glycine max; Inactivation, Metabolic; Male; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Thioglycosides; Thyroxine; Triiodothyronine; Weight Gain | 1990 |
Role of cytochrome P450 in the control of the production of erythropoietin.
Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoietin; Humans; Liver Neoplasms; Methylcholanthrene; Metyrapone; Microsomes; Oxygen; Phenobarbital; Thyroxine; Triiodothyronine; Tumor Cells, Cultured | 1990 |
Evaluation of thyroid gland activity by hormone assays and flow cytometry in rats.
Topics: Animals; Antithyroid Agents; Cell Cycle; Flow Cytometry; Male; Methimazole; Phenobarbital; Phenylenediamines; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1988 |
In vitro accumulation of thyroid hormones by cultured rat hepatocytes and the biliary excretion of iodothyronines in rats treated with a novel histamine H2-receptor antagonist.
Topics: Animals; Bile; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Histamine H2 Antagonists; Liver; Male; Phenobarbital; Pyrimidinones; Rats; Rats, Inbred Strains; Temperature; Thyroid Hormones; Thyroxine; Triazoles; Triiodothyronine | 1989 |
Relation between renal and hepatic excretion of drugs. XII. Influence of dexamethasone, triiodothyronine, or phenobarbital on the elimination of sulfonamides in rats of different ages.
Topics: Animals; Dexamethasone; Diuresis; Female; Kidney; Liver; Phenobarbital; Rats; Rats, Inbred Strains; Sulfonamides; Triiodothyronine | 1989 |
[Effects of 3,5,3'-triiodo-L-thyronine on the enzymes responsible for the metabolism of xenobiotics in the rat after increase in the dietary supply of cholesterol].
Topics: Animals; Cholesterol, Dietary; Cytochrome P-450 Enzyme System; Hyperthyroidism; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Triiodothyronine; Xenobiotics | 1988 |
Thyroid function in children with long-term anticonvulsant treatment.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Infant; Male; Osmolar Concentration; Phenobarbital; Resins, Plant; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Valproic Acid | 1987 |
Comparison of covalent binding from halothane metabolism in hepatic microsomes from phenobarbital-induced and hyperthyroid rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Glutathione; Halothane; Hyperthyroidism; Lipid Metabolism; Male; Microsomes, Liver; NADP; Phenobarbital; Proteins; Pyridines; Rats; Rats, Inbred Strains; Triiodothyronine | 1988 |
[Serum levels of triiodothyronine, thyroxine and thyrotropin in children with epilepsy treated with amizepine, luminal and mizodine in a monotherapy system. Preliminary report].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbital; Primidone; Thyrotropin; Thyroxine; Triiodothyronine | 1988 |
Failure of phenobarbitone to potentiate the adverse effects of two ethylene-bis-dithiocarbamate (EBDC) fungicides.
Topics: Animals; Body Weight; Drug Synergism; Female; Liver; Male; Maneb; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Thiocarbamates; Thyroid Gland; Thyroxine; Triglycerides; Triiodothyronine; Zineb | 1988 |
Proliferative response of putative preneoplastic hepatocytes to triiodothyronine, aminoacids, glucagon and heparine.
Topics: Amino Acids; Animals; Cell Division; Diethylnitrosamine; Glucagon; Heparin; Hyperplasia; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains; Triiodothyronine | 1988 |
Effect of phenobarbital & 3-methylcholanthrene treatment on thyroid hormones in rat.
Topics: Animals; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyroxine; Triiodothyronine | 1987 |
Halothane hepatotoxicity--again?
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Guinea Pigs; Halothane; Humans; Hypoxia; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Rats; Triiodothyronine | 1986 |
The influence of triiodothyronine (T3) and inducers on hepatic drug metabolism in rats of different ages.
Topics: Age Factors; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Coumarins; Cytochrome P-450 Enzyme System; Ethylmorphine; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Triiodothyronine | 1985 |
Hypometabolism in allergy: a review for otolaryngologists.
Topics: Adult; Animals; Basal Metabolism; Cattle; Desensitization, Immunologic; Energy Transfer; Female; Humans; Hypersensitivity; Male; Middle Aged; Phenobarbital; Protein Biosynthesis; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Triiodothyronine | 1974 |
[Lithium therapy of thyrotoxicosis. Clinical experiences and results with a new therapeutic principle].
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Hyperthyroidism; Iodine Radioisotopes; Lithium; Long-Term Care; Male; Middle Aged; Phenobarbital; Prednisone; Technetium; Thyroid Crisis; Thyroxine; Triiodothyronine | 1973 |
Carcinogens 3,4-benzpyrene and 3-methylcholanthrene: induction of mitochondrial oxidative enzymes.
Topics: Animals; Benzopyrenes; Dactinomycin; Dihydrolipoamide Dehydrogenase; Electron Transport Complex IV; Enzyme Induction; Glutamate Dehydrogenase; Glycerolphosphate Dehydrogenase; Hydroxybutyrate Dehydrogenase; L-Lactate Dehydrogenase; Malate Dehydrogenase; Methylcholanthrene; Mitochondria, Liver; Phenobarbital; Rats; Stimulation, Chemical; Succinate Dehydrogenase; Tetrazolium Salts; Triiodothyronine | 1968 |
Demonstration of membrane-linked iodoprotein in hepatic microsomes following metabolism of the thyroid hormones.
Topics: Animals; Centrifugation, Density Gradient; Glucose-6-Phosphatase; Iodine; Iodine Isotopes; Iodoproteins; Liver; Membranes; Microsomes, Liver; Phenobarbital; Proteins; Rats; Ribosomes; RNA; Serum Albumin, Radio-Iodinated; Spectrophotometry; Thyroxine; Triiodothyronine | 1970 |
Phenobarbital-induced synthesis of the microsomal drug-metabolizing enzyme system and its relationship to the proliferation of endoplasmic membranes. A morphological and biochemical study.
Topics: Aminopyrine; Animals; Carbon Monoxide; Codeine; Dactinomycin; Endoplasmic Reticulum; In Vitro Techniques; Liver; Microscopy, Electron; Microsomes; NADP; Nitrosamines; Oxidoreductases; Phenobarbital; Pigments, Biological; Puromycin; Rats; Thyroidectomy; Triiodothyronine | 1965 |
Prevention by catatoxic steroids of lithocholic acid-induced biliary concrements in the rat.
Topics: Animals; Bile Acids and Salts; Body Weight; Common Bile Duct; Female; Gallstones; Jaundice; Lithocholic Acid; Liver; Nitriles; Phenobarbital; Phenytoin; Prednisolone; Propionates; Rats; Steroids; Thyroxine; Triamcinolone; Triiodothyronine | 1972 |
Effects of phenobarbital on thyroxine and triiodothyronine kinetics in Graves' disease.
Topics: Feces; Female; Graves Disease; Humans; Iodine Isotopes; Kinetics; Liver; Male; Phenobarbital; Radioimmunoassay; Thyroxine; Triiodothyronine | 1973 |
[Thyrotoxic crisis: symptoms and therapy (author's transl)].
Topics: Adult; Aged; Ascorbic Acid; Body Temperature; Contrast Media; Female; First Aid; Germany, West; Humans; Iodides; Iodine; Male; Methimazole; Middle Aged; Phenobarbital; Prednisolone; Tachycardia; Thyroid Crisis; Triiodothyronine | 1973 |
The metabolic significance of exchangeable cellular thyroxine.
Topics: Animals; Biological Transport; Humans; Iodine; Iodine Isotopes; Kidney; Kinetics; Liver; Phenobarbital; Rats; Serum Albumin, Radio-Iodinated; Stimulation, Chemical; Thyroid Gland; Thyroidectomy; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1969 |
Phenobarbital, hormones, and bilirubin.
Topics: Bilirubin; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infant, Newborn; Phenobarbital; Triiodothyronine | 1969 |
Differences in primary cellular factors influencing the metabolism and distribution of 3,5,3'-L-triiodothyronine and L-thyroxine.
Topics: Animals; Feces; Histocytochemistry; Iodine Radioisotopes; Liver; Metabolic Clearance Rate; Phenobarbital; Rats; Thyroxine; Triiodothyronine | 1970 |
Effect of sodium phenobarbital on bilirubin metabolism in an infant with congenital, nonhemolytic, unconjugated hyperbilirubinemia, and kernicterus.
Topics: Bilirubin; Carbon Isotopes; Crystallization; Growth Hormone; Humans; Hyperbilirubinemia, Hereditary; Infant; Kernicterus; Kinetics; Liver; Male; Phenobarbital; Triiodothyronine; Tritium | 1969 |
Increased deiodination of L-thyroxine and L-triiodothyronine by liver microsomes from rats treated with phenobarbital.
Topics: Animals; Enzyme Induction; Iodine; Iodine Isotopes; Kinetics; Liver; Male; Microsomes; Monoiodotyrosine; Phenobarbital; Rats; Stimulation, Chemical; Thyroxine; Triiodothyronine | 1969 |
Barbiturate mortality in hypothyroid and hyperthyroid rats.
Topics: Amobarbital; Animals; Barbiturates; Basal Metabolism; Body Temperature; Body Weight; Hexobarbital; Hyperthyroidism; Hypothyroidism; Male; Pentobarbital; Phenobarbital; Rats; Thiopental; Thyroidectomy; Triiodothyronine; Zoxazolamine | 1969 |
Tissue iodoprotein formation during the peripheral metabolism of the thyroid hormones.
Topics: Animals; Cell Nucleus; Iodine; Kidney; Kinetics; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Muscles; Myocardium; Phenobarbital; Protein Binding; Rats; Thyroxine; Triiodothyronine | 1969 |
[Effects of phenobarbital on thyroid function in childhood. Iatrogenic TBG deficiency].
Topics: Child; Child, Preschool; Female; Humans; Iatrogenic Disease; Infant; Male; Phenobarbital; Seizures, Febrile; Thyroid Gland; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1984 |
Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fasting; Fluorides; Halothane; Hypoxia; Liver Diseases; Male; Phenobarbital; Rats; Rats, Inbred Strains; Starvation; Triiodothyronine | 1983 |
The effects on rat thyroid function of an hepatic microsomal enzyme inducer.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Depression, Chemical; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Phenobarbital; Pituitary Gland; Rats; Rats, Inbred Strains; Thyroid Function Tests; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1993 |
Depletion of cytochrome P-450 by thyroid hormone and cobalt-protoporphyrin IX in rat liver: evidence that susceptibility varies among forms of the heme protein.
Topics: 5-Aminolevulinate Synthetase; Animals; Blotting, Western; Cytochrome P-450 Enzyme System; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Heme Oxygenase (Decyclizing); Isoenzymes; Liver; Male; Phenobarbital; Protoporphyrins; Rats; Rats, Sprague-Dawley; Thyroidectomy; Triiodothyronine | 1995 |
The regulation by gender, strain, dose, and feeding status of the induction of multiple forms of cytochrome P450 isozymes in rat hepatic microsomes by 2,4,5,2',4',5'-hexachlorobiphenyl.
Topics: Animal Feed; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; GABA Modulators; Growth Hormone; Immunoblotting; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Sex Characteristics; Species Specificity; Structure-Activity Relationship; Testosterone; Triiodothyronine | 1996 |
[Neonatal Basedow's disease in twins from a mother with severe T3 hyperthyroidism].
Topics: Adrenergic beta-Antagonists; Adult; Antithyroid Agents; Autoantibodies; Developmental Disabilities; Diseases in Twins; Female; Fetal Blood; Graves Disease; Humans; Hypnotics and Sedatives; Infant, Newborn; Infectious Disease Transmission, Vertical; Iodide Peroxidase; Microcephaly; Phenobarbital; Pregnancy; Pregnancy Complications; Propranolol; Propylthiouracil; Receptors, Thyrotropin; Thyroxine; Triiodothyronine; Twins, Dizygotic | 1997 |
In vitro inhibition of thyroid hormone sulfation by hydroxylated metabolites of halogenated aromatic hydrocarbons.
Topics: Animals; Benzofurans; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Diiodothyronines; Dioxins; Hydrocarbons, Halogenated; Hydroxylation; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfotransferases; Sulfur; Triiodothyronine | 1998 |
Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in epileptic dogs treated with anticonvulsants.
Topics: Animals; Anticonvulsants; Bromides; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Female; Male; Phenobarbital; Potassium Compounds; Prospective Studies; Thyrotropin; Thyroxine; Triiodothyronine | 1999 |
Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy.
Topics: Animals; Cell Count; Cell Division; Chlorodiphenyl (54% Chlorine); Enzyme Activation; Hyperplasia; Hypertrophy; Male; Methylcholanthrene; Organ Size; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1999 |
Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Hypothyroidism; Male; Phenobarbital; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid | 1999 |
Differential effects of microsomal enzyme inducers on in vitro thyroxine (T(4)) and triiodothyronine (T(3)) glucuronidation.
Topics: Animals; Chlorodiphenyl (54% Chlorine); Detergents; Enzyme Induction; Glucuronides; Glucuronosyltransferase; In Vitro Techniques; Iodine Radioisotopes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroxine; Triiodothyronine | 2000 |
Thyroid hypertrophic effect of semotiadil fumarate, a new calcium antagonist, in rats.
Topics: Animals; Calcium Channel Blockers; Female; Glucuronosyltransferase; Hyperplasia; Hypertrophy; Liver; Microsomes, Liver; Nicardipine; Phenobarbital; Propylthiouracil; Rats; Rats, Wistar; Thiazoles; Thyroid Diseases; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2000 |
Thyroid hyperactivity induced by methimazole, spironolactone and phenobarbital in marmosets (Callithrix jacchus): histopathology, plasma thyroid hormone levels and hepatic T4 metabolism.
Topics: Animals; Anticonvulsants; Antithyroid Agents; Biopsy; Callithrix; Cytochrome P-450 Enzyme System; Immunohistochemistry; Liver; Male; Methimazole; Microscopy, Electron; Mineralocorticoid Receptor Antagonists; Phenobarbital; Radioimmunoassay; Spironolactone; Thyroid Diseases; Thyroid Gland; Thyroxine; Triiodothyronine | 2000 |
Synergistic effects of high-dose soybean intake with iodine deficiency, but not sulfadimethoxine or phenobarbital, on rat thyroid proliferation.
Topics: Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Female; Glycine max; Hyperplasia; Iodine; Phenobarbital; Rats; Rats, Inbred F344; Sulfadimethoxine; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; Thyroxine; Triiodothyronine | 2001 |
Enhanced rat Hershberger assay appears reliable for detection of not only (anti-)androgenic chemicals but also thyroid hormone modulators.
Topics: Administration, Oral; Androgen Antagonists; Animals; Antithyroid Agents; Body Weight; Castration; Dichlorodiphenyl Dichloroethylene; Drug Evaluation, Preclinical; Eating; Injections, Subcutaneous; Male; Organ Size; Phenobarbital; Propylthiouracil; Rats; Rats, Inbred Strains; Reproducibility of Results; Testosterone Propionate; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2004 |
Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism.
Topics: Animals; Anticonvulsants; Blotting, Northern; Cell Proliferation; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Male; Mice; Models, Biological; Mutation; Phenobarbital; Proliferating Cell Nuclear Antigen; Propylthiouracil; Pyridines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Thyroid Hormones; Thyroid Neoplasms; Thyroxine; Transcription Factors; Triiodothyronine; Xenobiotics | 2005 |
Decrease in serum thyroxine level by phenobarbital in rats is not necessarily dependent on increase in hepatic UDP-glucuronosyltransferase.
Topics: Animals; Anticonvulsants; Enzyme Induction; Glucuronosyltransferase; Iodide Peroxidase; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Gunn; Rats, Wistar; Thyroxine; Triiodothyronine | 2005 |
The nuclear receptor constitutively active/androstane receptor regulates type 1 deiodinase and thyroid hormone activity in the regenerating mouse liver.
Topics: Animals; Constitutive Androstane Receptor; Female; Gene Expression Regulation, Enzymologic; Hepatectomy; Iodide Peroxidase; Kruppel-Like Transcription Factors; Liver; Liver Regeneration; Mice; Mice, Inbred C3H; Mice, Knockout; Phenobarbital; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Triiodothyronine; Tyrosine Transaminase | 2007 |
Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats.
Topics: Animals; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Hyperplasia; Hypertrophy; Iodine Radioisotopes; Male; Perchlorates; Phenobarbital; Potassium Compounds; Potassium Iodide; Propylthiouracil; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Toxicity Tests; Triiodothyronine | 2007 |
Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.
Topics: Animals; Cells, Cultured; Drug Synergism; Hepatocytes; Male; Phenobarbital; PPAR alpha; Pyrimidines; Rats; Rats, Wistar; Thyroxine; Triiodothyronine | 2009 |
A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents.
Topics: Animals; Cricetinae; Glucuronides; Guinea Pigs; Hypnotics and Sedatives; Liver; Male; Mice; Phenobarbital; Rats; Rats, Wistar; Sulfotransferases; Thyroxine; Triiodothyronine | 2010 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Hypothyroidism caused by phenobarbital affects patterns of estrous cyclicity in rats.
Topics: Animals; Estradiol; Estrous Cycle; Female; Hypothyroidism; Ovary; Phenobarbital; Progesterone; Prolactin; Rats; Thyrotropin; Thyroxine; Triiodothyronine | 2011 |