triiodothyronine has been researched along with mgl-3196 in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Banner, B; Conde-Knape, K; Danzi, S; Dvorozniak, M; Haynes, NE; Huang, KS; Kelly, MJ; Klein, I; Larigan, JD; Mennona, F; Pietranico-Cole, S; Qian, Y; Reynolds, CH; Scott, N; So, SS; Taub, R; Thakkar, K; Tilley, J; Vermeulen, J | 1 |
| Fenaux, M; Halcomb, RL; Jones, CT; Kirschberg, TA; Klucher, K; Wang, Y; Xu, Y | 1 |
| Li, J; Li, Q; Li, Y; Lu, Z; Wu, D; Wu, X; Xiang, Q; Xu, Y; Yao, B; Yu, H; Zhang, C; Zhang, Y; Zhao, S; Zhuang, X | 1 |
| Chabot-Blanchet, M; Chiang, E; Guertin, MC; Kelly, MJ; Reeves, RA; Tardif, JC; Taub, R | 1 |
| Zucchi, R | 1 |
| Führer, D; Hönes, GS; Hoppe, C; König, J; Moeller, LC; Sivakumar, RG | 1 |
1 review(s) available for triiodothyronine and mgl-3196
| Article | Year |
|---|---|
Thyroid Hormone Analogues: An Update.
Topics: Acetates; Anilides; Animals; Central Nervous System Diseases; Clinical Trials as Topic; Diiodothyronines; Drug Design; Dyslipidemias; Humans; Liver Diseases; Male; Mice; Mutation; Non-alcoholic Fatty Liver Disease; Phenols; Pyridazines; Rats; Signal Transduction; Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta; Thyroid Hormones; Thyronines; Triiodothyronine; Uracil | 2020 |
1 trial(s) available for triiodothyronine and mgl-3196
| Article | Year |
|---|---|
Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist.
Topics: Adult; Body Mass Index; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Healthy Volunteers; Humans; Hypercholesterolemia; Liver; Male; Middle Aged; Patient Safety; Pyridazines; Thyroid Gland; Thyroid Hormone Receptors beta; Thyrotropin; Thyroxine; Time Factors; Triiodothyronine; Uracil | 2013 |
4 other study(ies) available for triiodothyronine and mgl-3196
| Article | Year |
|---|---|
Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dys
Topics: Animals; Bone Density; Clinical Trials as Topic; Drug Discovery; Dyslipidemias; Humans; Male; Mice; Mice, Inbred C57BL; Pyridazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thyroid Hormone Receptors beta; Uracil | 2014 |
Selective thyroid hormone receptor β agonists with oxadiazolone acid isosteres.
Topics: Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Oxadiazoles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thyroid Hormone Receptors beta | 2020 |
Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist.
Topics: Humans; Mutation; Thyroid Hormone Receptors beta; Thyroid Hormone Resistance Syndrome; Thyroid Hormones | 2022 |
Cell-Specific Transport and Thyroid Hormone Receptor Isoform Selectivity Account for Hepatocyte-Targeted Thyromimetic Action of MGL-3196.
Topics: Animals; Cadaver; HEK293 Cells; Hepatocytes; Humans; Mice; Mice, Knockout; Protein Isoforms; Receptors, Thyroid Hormone; Thyroid Hormone Receptors beta; Triiodothyronine | 2022 |