Compounds > triiodothyronine
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triiodothyronine and ketoconazole

triiodothyronine has been researched along with ketoconazole in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Breitman, TR; Takahashi, N1
García, R; Henríquez-La Roche, C; Herrera, J; Rodríguez-Iturbe, B; Rubio, L; Salgado, O1
Caksen, H; Coksevim, B; Kurtoğlu, S; Okumuş, Y; Oztürk, F; Tutuş, A1
Ali, EM; Ashraf, RM; Ibrahim, W; Tousson, E1

Reviews

1 review(s) available for triiodothyronine and ketoconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for triiodothyronine and ketoconazole

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Covalent modification of proteins by ligands of steroid hormone receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-15, Volume: 89, Issue:22

    Topics: Calcitriol; Dinoprostone; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Estradiol; Humans; Iodine Radioisotopes; Ketoconazole; Kinetics; Leukemia, Promyelocytic, Acute; Ligands; Molecular Weight; Neoplasm Proteins; Progesterone; Protein Binding; Receptors, Steroid; Thyroxine; Triiodothyronine; Tritium; Tumor Cells, Cultured

1992
Effects of low-dose ketoconazole on thyroid hormones in renal transplant recipients.
    Transplantation proceedings, 1996, Volume: 28, Issue:6

    Topics: Adult; Antifungal Agents; Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Ketoconazole; Kidney Transplantation; Male; Prednisone; Thyrotropin; Thyroxine; Triiodothyronine

1996
Low dose ketoconazole therapy and thyroid functions in rats.
    Acta medica (Hradec Kralove), 2002, Volume: 45, Issue:4

    Topics: Animals; Antifungal Agents; Body Weight; Ketoconazole; Organ Size; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2002
Histopathological and immunohistochemical alterations in rat heart after thyroidectomy and the role of hemin and ketoconazole in treatment.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:8

    Topics: Animals; Enzyme Induction; Heart Ventricles; Heme Oxygenase (Decyclizing); Hemin; Immunohistochemistry; Ketoconazole; Male; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Thyroidectomy; Thyrotropin; Triiodothyronine

2012