Compounds > triiodothyronine
Page last updated: 2024-08-17

triiodothyronine and kb 141

triiodothyronine has been researched along with kb 141 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (85.71)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bladh, LG; Garcia Collazo, AM; Garg, N; George, R; Grover, G; Husman, B; Koehler, K; Li, YL; Litten, C; Ljunggren, J; Malm, J; Mellin, C; Mellström, K; Persson, K; Sleph, PG; Ye, L1
Dejneka, T; Devasthale, P; Doweyko, AM; Einspahr, H; Färnegårdh, M; Friends, TJ; Grynfarb, M; Hangeland, JJ; Husman, B; Koehler, K; Ljunggren, J; Malm, J; Mellström, K; Ryono, DE; Sack, JS; Sandberg, J; Sheppard, C1
Doweyko, AM; Friends, TJ; Grynfarb, M; Hangeland, JJ; Mellström, K; Ryono, DE; Sandberg, J1
Färnegård, M; Garcia Collazo, AM; Garg, N; Grynfarb, M; Husman, B; Koehler, KF; Li, YL; Litten, C; Malm, J; Mellström, K; Sandberg, J1
Gramatica, P; Liu, H1
Agback, P; Brigance, RP; Caringal, Y; Garcia Collazo, AM; Garg, N; Grover, G; Grynfarb, M; Li, YL; Litten, C; Malm, J; Mellström, K; Meng, W; Norin, T; Rahimi-Ghadim, M; Rehnmark, S; Ryono, DE; Sandberg, J; Washburn, WN; Zhang, M1
Boyer, SH; Cable, EE; Erion, MD; Finn, PD; Fujitaki, JM; Hou, J; Ito, BR; Jiang, H; Linemeyer, DL; van Poelje, PD; Zhang, BH1
Boyer, SH; Cable, EE; Erion, MD; Fujitaki, JM; Godwin, JL; Hecker, SJ; Hou, J; Jacintho, JD; Jiang, H; Li, H; Li, W; Reddy, MV; Schulz, WG; Wu, R1
Banner, B; Conde-Knape, K; Danzi, S; Dvorozniak, M; Haynes, NE; Huang, KS; Kelly, MJ; Klein, I; Larigan, JD; Mennona, F; Pietranico-Cole, S; Qian, Y; Reynolds, CH; Scott, N; So, SS; Taub, R; Thakkar, K; Tilley, J; Vermeulen, J1
Baxter, JD; Bladh, LG; Egan, D; George, R; Grover, GJ; Horvath, R; Li, YL; Malm, J; Mellström, K; Mookhtiar, K; Sleph, PG; Smith, MA; Speelman, J; Vennström, B; Ye, L1
Angelin, B; Baxter, J; Johansson, L; Lundåsen, T; Parini, P; Rudling, M; Scanlan, TS; Webb, P1
Honjo, Y; Kawai, K; Nakamura, H; Sasaki, S1
Josseaume, C; Lorcy, Y1
Noszál, B; Tóth, G1

Reviews

2 review(s) available for triiodothyronine and kb 141

ArticleYear
[Thyroid hormones and lipid metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:12

    Topics: Animals; Cholesterol, LDL; Drug Design; Humans; Hypercholesterolemia; Hypothyroidism; Lipid Metabolism; Phenyl Ethers; Phenylacetates; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Receptors, Thyroid Hormone; Transcription Factors; Transcription, Genetic; Triiodothyronine

2006
[Thyroid hormones and their precursors I. Biochemical properties].
    Acta pharmaceutica Hungarica, 2013, Volume: 83, Issue:2

    Topics: Acetates; Biological Transport; Diiodothyronines; Diiodotyrosine; Humans; Hydrogen-Ion Concentration; Membrane Transport Proteins; Monoiodotyrosine; Phenols; Phenyl Ethers; Phenylacetates; Protein Isoforms; Receptors, Thyroid Hormone; Structure-Activity Relationship; Thyroid Hormones; Thyroxine; Thyroxine-Binding Globulin; Triiodothyronine; Triiodothyronine, Reverse

2013

Other Studies

12 other study(ies) available for triiodothyronine and kb 141

ArticleYear
Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
    Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9

    Topics: Alkaline Phosphatase; Animals; Binding Sites; CHO Cells; Cholesterol; Cricetinae; Crystallography, X-Ray; Genes, Reporter; Heart Rate; Humans; Ligands; Male; Phenylacetates; Protein Isoforms; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta; Thyrotropin; Triiodothyronine

2003
Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta.
    Bioorganic & medicinal chemistry letters, 2004, Jul-05, Volume: 14, Issue:13

    Topics: 2-Propanol; Amino Acids; Binding Sites; Cell Line; Crystallography, X-Ray; Drug Design; Inhibitory Concentration 50; Ligands; Structure-Activity Relationship; Thyroid Hormone Receptors beta; Thyroid Hormones; Triiodothyronine

2004
A new class of high affinity thyromimetics containing a phenyl-naphthylene core.
    Bioorganic & medicinal chemistry letters, 2005, Oct-15, Volume: 15, Issue:20

    Topics: Models, Molecular; Naphthalenes; Receptors, Thyroid Hormone; Structure-Activity Relationship; Thyroid Hormones

2005
Thyroid receptor ligands. Part 4: 4'-amido bioisosteric ligands selective for the thyroid hormone receptor beta.
    Bioorganic & medicinal chemistry letters, 2006, Feb-15, Volume: 16, Issue:4

    Topics: Amides; Crystallography, X-Ray; Drug Design; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Phenyl Ethers; Phenylacetates; Protein Conformation; Protein Structure, Tertiary; Structure-Activity Relationship; Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta; Thyroid Hormones; Triiodothyronine

2006
QSAR study of selective ligands for the thyroid hormone receptor beta.
    Bioorganic & medicinal chemistry, 2007, Aug-01, Volume: 15, Issue:15

    Topics: Antithyroid Agents; Combinatorial Chemistry Techniques; Ligands; Models, Biological; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Software; Thyroid Hormone Receptors beta

2007
Thyroid receptor ligands. Part 8: Thyromimetics derived from N-acylated-alpha-amino acid derivatives displaying modulated pharmacological selectivity compared with KB-141.
    Bioorganic & medicinal chemistry letters, 2007, Aug-01, Volume: 17, Issue:15

    Topics: Amino Acids; Animals; CHO Cells; Cholesterol, Dietary; Cricetinae; Cricetulus; Ligands; Molecular Mimicry; Phenyl Ethers; Phenylacetates; Radioligand Assay; Rats; Receptors, Thyroid Hormone

2007
Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Sep-25, Volume: 104, Issue:39

    Topics: Animals; Chemistry, Pharmaceutical; Cholesterol; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Liver; Male; Mice; Mice, Inbred C57BL; Models, Biological; Muscles; Rats; Rats, Sprague-Dawley; Thyroid Hormone Receptors beta; Triglycerides

2007
Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Animals; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Glycerolphosphate Dehydrogenase; Hypercholesterolemia; Ligands; Liver; Molecular Structure; Organophosphonates; Prodrugs; Rats; Rats, Sprague-Dawley; Receptors, Thyroid Hormone; Stereoisomerism; Structure-Activity Relationship

2008
Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dys
    Journal of medicinal chemistry, 2014, May-22, Volume: 57, Issue:10

    Topics: Animals; Bone Density; Clinical Trials as Topic; Drug Discovery; Dyslipidemias; Humans; Male; Mice; Mice, Inbred C57BL; Pyridazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thyroid Hormone Receptors beta; Uracil

2014
Selective thyroid hormone receptor-beta activation: a strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-19, Volume: 100, Issue:17

    Topics: Animals; Anticholesteremic Agents; Cardiovascular System; Cholesterol; Cholesterol, Dietary; Humans; In Vitro Techniques; Kinetics; Lipoprotein(a); Macaca fascicularis; Mice; Mice, Knockout; Phenyl Ethers; Phenylacetates; Rats; Rats, Sprague-Dawley; Receptors, Thyroid Hormone; Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta; Triiodothyronine; Weight Loss

2003
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Jul-19, Volume: 102, Issue:29

    Topics: Acetates; Analysis of Variance; Animals; Bile Acids and Salts; Cardiovascular Diseases; CD36 Antigens; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Feces; Gene Expression Regulation; Hypercholesterolemia; Immunoblotting; Liver; Male; Mice; Mice, Inbred C57BL; Phenols; Phenyl Ethers; Phenylacetates; Receptors, Immunologic; Receptors, Scavenger; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Hormone Receptors beta; Triglycerides; Triiodothyronine

2005
[Thyroid hormone analogs: an important biological supply and new therapeutic possibilities].
    Annales d'endocrinologie, 2008, Volume: 69 Suppl 1

    Topics: Acetates; Anilides; Anticholesteremic Agents; Humans; Hypolipidemic Agents; Phenols; Phenyl Ethers; Phenylacetates; Receptors, Thyroid Hormone; Signal Transduction; Thyroid Hormones; Triiodothyronine

2008