Page last updated: 2024-08-17

triiodothyronine and clofibrate

triiodothyronine has been researched along with clofibrate in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's5 (25.00)18.2507
2000's4 (20.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
De Grimal, P; Goudonnet, H; Truchot, R1
Pösö, AR1
Fukuda, H; Kamio, N; Kobayashi, I; Maruta, S; Mori, M; Ohshima, K; Shimomura, Y1
Kato, R; Murayama, N; Sato, T; Yamazoe, Y1
Baes, MI; Castelein, H; Declercq, PE; Mannaerts, GP1
Barlow, JW; Crowe, TC; Loidl, NM; Payne, KL; Stockigt, JR; Topliss, DJ1
Carlisle, TL; el Khadir-Mounier, C; Goodridge, AG; Roncero, C; Thurmond, DC1
Miller, CW; Ntambi, JM; Waters, KM1
Grott, S; Kutz, S; Radtke, C; Seitz, HJ; Weitzel, JM1
STRISOWER, B; STRISOWER, EH1
Eder, K; Hirche, F; Kluge, H; Luci, S1
Cruz, A; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Soler, A; Vargas, F1

Reviews

2 review(s) available for triiodothyronine and clofibrate

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for triiodothyronine and clofibrate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
[Effects of methy-2[(chloro-4'-benzoyl)-4-phenoxy]-2 propionic acid on the respiratory activity of isolated rat liver mitochondria].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1977, Volume: 171, Issue:1

    Topics: Animals; Clofibrate; In Vitro Techniques; Mitochondria, Liver; Oxygen Consumption; Propionates; Rats; Triiodothyronine; Uncoupling Agents

1977
Influence of the activity of mitochondrial alpha-glycerophosphate oxidase on the alpha-glycerophosphate shuttle during ethanol oxidation.
    FEBS letters, 1977, Nov-15, Volume: 83, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Clofibrate; Ethanol; Glycerolphosphate Dehydrogenase; Glycerophosphates; Male; Mitochondria, Liver; Rats; Triiodothyronine

1977
Clofibrate and a related compound suppress TSH secretion in primary hypothyroidism.
    Acta endocrinologica, 1980, Volume: 94, Issue:1

    Topics: Adult; Clofibrate; Female; Glycolates; Humans; Hypothyroidism; Male; Meclofenoxate; Thyrotropin; Thyroxine; Triiodothyronine

1980
Suppression of clofibrate-induction of peroxisomal and microsomal fatty acid-oxidizing enzymes by growth hormone and thyroid hormone in primary cultures of rat hepatocytes.
    Biochimica et biophysica acta, 1995, Jun-06, Volume: 1256, Issue:3

    Topics: Acyl-CoA Oxidase; Animals; Cells, Cultured; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Fatty Acids; Female; Growth Hormone; Liver; Male; Microbodies; Microsomes; Mixed Function Oxygenases; Oxidation-Reduction; Oxidoreductases; Pyrimidines; Rats; Rats, Sprague-Dawley; Triiodothyronine

1995
Peroxisome proliferators and T3 operate by way of distinct receptors.
    FEBS letters, 1993, Oct-11, Volume: 332, Issue:1-2

    Topics: Animals; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Clofibrate; Cross Reactions; Mice; Microbodies; Receptors, Cytoplasmic and Nuclear; Receptors, Thyroid Hormone; Signal Transduction; Transcription Factors; Transfection; Triiodothyronine

1993
Differential modulation of thyroid hormone responsiveness by retinoids in a human cell line.
    Endocrinology, 1996, Volume: 137, Issue:8

    Topics: Carcinoma, Hepatocellular; Clofibrate; Dose-Response Relationship, Drug; Humans; Sex Hormone-Binding Globulin; Stereoisomerism; Thyroxine-Binding Proteins; Tretinoin; Triiodothyronine; Tumor Cells, Cultured; Vitamin D

1996
Malic enzyme gene in chick embryo hepatocytes in culture: clofibrate regulates responsiveness to triiodothyronine.
    Journal of lipid research, 1996, Volume: 37, Issue:10

    Topics: Animals; Base Sequence; Cells, Cultured; Chick Embryo; Clofibrate; Consensus Sequence; DNA; Gene Expression Regulation, Enzymologic; Hypolipidemic Agents; Liver; Malate Dehydrogenase; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Triiodothyronine

1996
Regulation of hepatic stearoyl-CoA desaturase gene 1 by vitamin A.
    Biochemical and biophysical research communications, 1997, Feb-03, Volume: 231, Issue:1

    Topics: Actins; Animals; Clofibrate; Diterpenes; Dose-Response Relationship, Drug; Fatty Acid Synthases; Gene Expression Regulation, Enzymologic; Liver; Male; Mice; Mice, Inbred BALB C; Microbodies; Receptors, Retinoic Acid; Retinoid X Receptors; Retinyl Esters; RNA, Messenger; Stearoyl-CoA Desaturase; Transcription Factors; Triiodothyronine; Vitamin A; Vitamin A Deficiency

1997
Hormonal regulation of multiple promoters of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene: identification of a complex hormone-response element in the ubiquitous promoter B.
    European journal of biochemistry, 2001, Volume: 268, Issue:14

    Topics: Animals; Base Sequence; Clofibrate; Gene Expression Regulation, Enzymologic; Glycerolphosphate Dehydrogenase; Hormones; Humans; Mitochondria; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Receptors, Thyroid Hormone; Response Elements; Steroids; Tretinoin; Triiodothyronine

2001
THE SEPARATE HYPOLIPOPROTEINEMIC EFFECTS OF DEXTROTHYROXINE AND ETHYL CHLOROPHENOXYISOBUTYRATE.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Androsterone; Biomedical Research; Blood Chemical Analysis; Blood Proteins; Body Weight; Butyrates; Clofibrate; Dextrothyroxine; Hypercholesterolemia; Lipids; Lipoproteins; Pharmacology; Thyroxine; Triiodothyronine

1964
Clofibrate increases hepatic triiodothyronine (T3)- and thyroxine (T4)-glucuronosyltransferase activities and lowers plasma T3 and T4 concentrations in pigs.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:11

    Topics: Animals; Body Weight; Clofibrate; Gene Expression; Glucuronosyltransferase; Hypolipidemic Agents; Liver; Male; Organ Size; PPAR alpha; Swine; Thyroid Gland; Thyroxine; Triiodothyronine

2006
Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats.
    American journal of hypertension, 2008, Volume: 21, Issue:3

    Topics: Animals; Blood Pressure; Body Temperature; Body Weight; Clofibrate; Disease Models, Animal; Glucuronosyltransferase; Heart Rate; Hyperthyroidism; Hypertrophy; Hypolipidemic Agents; Kidney; Male; Myocardium; PPAR alpha; Rats; Rats, Wistar; Thyroxine; Triiodothyronine

2008