trihexyphenidyl has been researched along with pirenzepine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhattacharjee, AK; Evans, SA; Gordon, RK; Pervitsky, D; Pomponio, JW | 1 |
| Ho, IK; Hoskins, B; Lim, DK | 1 |
| Giachetti, A; Giraldo, E; Ladinsky, H; Montagna, E | 1 |
| Hung, WC; Wei, JW | 1 |
| Nilvebrant, L; Sparf, B | 1 |
| Heathcote, BV; Parry, M | 1 |
| Besson, MJ; Mavridis, M; Rogard, M | 1 |
| Bymaster, FP; Heath, I; Hendrix, JC; Shannon, HE | 1 |
| Bolaños-Badillo, E; González-Sánchez, H; Prado-Alcalá, RA; Quirarte, GL; Roldán, G | 1 |
| Fowler, SC; Stanford, JA | 1 |
| Ebinger, G; Izurieta-Sánchez, P; Michotte, Y; Sarre, S | 1 |
| Marsh, C; Preskorn, SH; Shad, MU | 1 |
| Katz, JL; Tanda, G | 1 |
13 other study(ies) available for trihexyphenidyl and pirenzepine
| Article | Year |
|---|---|
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
Topics: Atropine; Computer Simulation; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Receptor, Muscarinic M1; Structure-Activity Relationship | 2013 |
Trihexyphenidyl enhances physostigmine prophylaxis against soman poisoning in guinea pigs.
Topics: Animals; Body Weight; Brain; Drinking; Drug Interactions; Guinea Pigs; Kinetics; Lethal Dose 50; Male; Membrane Proteins; Physostigmine; Pirenzepine; Quinuclidinyl Benzilate; Reflex; Seizures; Soman; Trihexyphenidyl | 1991 |
Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Blood Pressure; Cyclohexanecarboxylic Acids; Decerebrate State; Dicyclomine; Electric Stimulation; In Vitro Techniques; Male; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Trihexyphenidyl; Vagus Nerve | 1986 |
Evidence for the coupling of muscarinic M1 receptors to polyphosphoinositide turnover in rat cortical synaptosomes.
Topics: Animals; Carbachol; Cerebellum; Cerebral Cortex; In Vitro Techniques; Male; Phosphatidylinositol Phosphates; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes; Trihexyphenidyl | 1989 |
Dicyclomine, benzhexol and oxybutynine distinguish between subclasses of muscarinic binding sites.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Cyclohexanecarboxylic Acids; Dicyclomine; Guinea Pigs; In Vitro Techniques; Male; Mandelic Acids; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Time Factors; Trihexyphenidyl; Urinary Bladder | 1986 |
Pirenzepine selectively inhibits gastric acid secretion: a comparative pharmacological study between pirenzepine and seven other antiacetylcholine drugs.
Topics: Acetylcholine; Animals; Atropine; Benzilates; Benzodiazepinones; Dose-Response Relationship, Drug; Gastric Acid; Glycopyrrolate; Male; Mice; Piperazines; Pirenzepine; Propantheline; Pupil; Pyrimidines; Quaternary Ammonium Compounds; Rats; Trihexyphenidyl | 1980 |
Chronic blockade of muscarinic cholinergic receptors by systemic trihexyphenidyl (Artane) administration modulates but does not mediate the dopaminergic regulation of striatal prepropeptide messenger RNA expression.
Topics: Animals; Autoradiography; Dopamine; Dynorphins; Enkephalins; In Situ Hybridization; Male; Muscarinic Antagonists; Neostriatum; Oxidopamine; Pirenzepine; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Substantia Nigra; Sympathectomy, Chemical; Tachykinins; Trihexyphenidyl | 1995 |
Comparative behavioral and neurochemical activities of cholinergic antagonists in rats.
Topics: Acetylcholine; Animals; Behavior, Animal; Brain Stem; Cerebral Cortex; Dopamine; Male; Mecamylamine; Memory; Neurotransmitter Agents; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine; Trihexyphenidyl | 1993 |
Selective M1 muscarinic receptor antagonists disrupt memory consolidation of inhibitory avoidance in rats.
Topics: Animals; Avoidance Learning; Biperiden; Dose-Response Relationship, Drug; Male; Memory; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine; Trihexyphenidyl | 1997 |
Similarities and differences between the subchronic and withdrawal effects of clozapine and olanzapine on forelimb force steadiness.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Tolerance; Forelimb; Male; Muscarinic Antagonists; Olanzapine; Pirenzepine; Quipazine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Tremor; Trihexyphenidyl | 1997 |
Muscarinic antagonists in substantia nigra influence the decarboxylation of L-dopa in striatum.
Topics: Analysis of Variance; Animals; Corpus Striatum; Decarboxylation; Diamines; Dopamine; Extracellular Space; gamma-Aminobutyric Acid; Levodopa; Male; Microdialysis; Muscarinic Antagonists; Neurotransmitter Agents; Parasympatholytics; Perfusion; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Substantia Nigra; Time Factors; Trihexyphenidyl | 2000 |
The economic consequences of a drug-drug interaction.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Depression; Drug Interactions; Female; Fluoxetine; Haloperidol; Health Care Costs; Humans; Olanzapine; Parkinson Disease; Pirenzepine; Selegiline; Trihexyphenidyl | 2001 |
Muscarinic preferential M(1) receptor antagonists enhance the discriminative-stimulus effects of cocaine in rats.
Topics: Animals; Cocaine; Data Interpretation, Statistical; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Trihexyphenidyl | 2007 |