Page last updated: 2024-08-16

trihexyphenidyl and orphenadrine

trihexyphenidyl has been researched along with orphenadrine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199022 (78.57)18.7374
1990's2 (7.14)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Marsden, CD1
Parkenberg, H1
di Costanzo, E; Schifano, F1
Götestam, KG; Vågen, R1
Bowers, MB; Roth, RH1
Birket-Smith, E1
Costall, B; Naylor, RJ1
Clark, MS; Palfreyman, ES; Palfreyman, MG1
Heikkila, RE; Orlansky, H1
Andersen, PR; Gibbs, P; Kubinski, H1
Ban, T; Hojo, M1
Florio, V; Longo, VG1
Hughes, RC; Polgar, JG; Walton, JN; Weightman, D1
Fouks, L; Houssait, A; Lerno, M; Périvier, E1
Burnett, GB; Creese, IC; Jolliff, LA; Prange, AJ; Synder, SH; Wilson, IC1
Best, NR; Maguire, J; Pullen, GP1
Berger, HJ; Buytenhuijs, EL; Cools, AR; Horstink, MW; Van Spaendonck, KP1
Buhrich, N; Kevans, P; Weller, A1
GILLINGHAM, FJ; KALYANARAMAN, S1
TURNER, JW1
STRANG, RR2
DRAPER, IT; JOHNS, RJ1

Reviews

2 review(s) available for trihexyphenidyl and orphenadrine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Advances in the management of parkinson's disease.
    Scottish medical journal, 1976, Volume: 21, Issue:3

    Topics: Amantadine; Anesthesia; Humans; Levodopa; Orphenadrine; Parasympatholytics; Parkinson Disease; Social Adjustment; Trihexyphenidyl

1976

Trials

2 trial(s) available for trihexyphenidyl and orphenadrine

ArticleYear
An experimental evaluation of the euphoric properties of antiparkinson drugs on psychotic patients.
    Acta psychiatrica Scandinavica, 1986, Volume: 74, Issue:5

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Euphoria; Female; Humans; Male; Middle Aged; Orphenadrine; Parkinson Disease, Secondary; Procyclidine; Psychotic Disorders; Pyrrolidines; Trihexyphenidyl

1986
Levodopa in Parkinsonism: the effects of withdrawal of anticholinergic drugs.
    British medical journal, 1971, May-29, Volume: 2, Issue:5760

    Topics: Dihydroxyphenylalanine; Drug Synergism; Drug Tolerance; Female; Humans; Male; Methods; Neurologic Manifestations; Orphenadrine; Parasympatholytics; Parkinson Disease; Salivation; Substance Withdrawal Syndrome; Time Factors; Tremor; Trihexyphenidyl

1971

Other Studies

24 other study(ies) available for trihexyphenidyl and orphenadrine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
[Treatment of parkinsonism].
    Ugeskrift for laeger, 1976, Apr-26, Volume: 138, Issue:18

    Topics: Amantadine; Benztropine; Biperiden; Humans; Levodopa; Orphenadrine; Parkinson Disease; Procyclidine; Trihexyphenidyl

1976
Excessive use of anticholinergic drugs in a sub-sample of Italian schizophrenics.
    International journal of clinical pharmacology, therapy, and toxicology, 1991, Volume: 29, Issue:5

    Topics: Adult; Biperiden; Female; Humans; Italy; Male; Middle Aged; Orphenadrine; Parasympatholytics; Patient Compliance; Procyclidine; Retrospective Studies; Sampling Studies; Schizophrenia; Trihexyphenidyl

1991
Interaction of atropine-like drugs with dopamine-containing neurones in rat brain.
    British journal of pharmacology, 1972, Volume: 44, Issue:2

    Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Dopamine; Homovanillic Acid; Male; Methyltyrosines; Neurons; Orphenadrine; Phenothiazines; Procyclidine; Rats; Time Factors; Trihexyphenidyl

1972
Abnormal involuntary movements induced by anticholinergic therapy.
    Acta neurologica Scandinavica, 1974, Volume: 50, Issue:6

    Topics: Aged; Biperiden; Dibenzazepines; Female; Humans; Mastication; Middle Aged; Movement Disorders; Orphenadrine; Parasympatholytics; Parkinson Disease; Phenothiazines; Procyclidine; Tremor; Trihexyphenidyl

1974
The relationship between the inhibition of dopamine uptake and the enhancement of amphetamine stereotypy.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Aug-15, Volume: 10, Issue:16

    Topics: Amantadine; Amphetamine; Animals; Behavior, Animal; Chlorpheniramine; Dopamine; Dopamine Antagonists; Drug Synergism; Histamine H1 Antagonists; Injections, Intraperitoneal; Male; Orphenadrine; Parasympatholytics; Parkinson Disease; Piperidines; Rats; Trihexyphenidyl

1971
Effects of benapyrzine, a new antiparkinson drug, on dopamine uptake into corpus striatum.
    European journal of pharmacology, 1974, Volume: 28, Issue:2

    Topics: Animals; Antiparkinson Agents; Benzilates; Catecholamines; Corpus Striatum; Dopamine; Ethylamines; Female; Hypothalamus; Imipramine; In Vitro Techniques; Kinetics; Orphenadrine; Propylamines; Rats; Scopolamine; Synaptosomes; Trihexyphenidyl; Tritium

1974
An evaluation of various antiparkinsonian agents as releasing agents and uptake inhibitors for 3H-dopamine in slices of rat neostriatum.
    European journal of pharmacology, 1974, Volume: 29, Issue:2

    Topics: Animals; Antiparkinson Agents; Benztropine; Catecholamines; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Diphenhydramine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Orphenadrine; Putamen; Rats; Serotonin; Trihexyphenidyl; Tritium

1974
Effects of neuropharmacological agents on in vitro formation of complexes between nucleic acids and proteins.
    Neuropharmacology, 1974, Volume: 13, Issue:2

    Topics: Animals; Benztropine; Cattle; Chlorpromazine; Codeine; Desipramine; DNA, Bacterial; Escherichia coli; Histones; Lysergic Acid Diethylamide; Morphine; Neostigmine; Nucleic Acids; Orphenadrine; Phenytoin; Protein Binding; Proteins; RNA, Bacterial; RNA, Ribosomal; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Trihexyphenidyl

1974
A comparative study of the effects of anti-parkinson drugs on the oxotremorine-induced EEG and muscular activities.
    Psychopharmacologia, 1971, Volume: 19, Issue:1

    Topics: Animals; Diphenhydramine; Drug Antagonism; Electroencephalography; Male; Muscle Tonus; Muscles; Orphenadrine; Parasympatholytics; Parkinson Disease; Propantheline; Propranolol; Pyrrolidinones; Rabbits; Scopolamine; Spasm; Tremorine; Trihexyphenidyl

1971
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
    Physiology & behavior, 1971, Volume: 6, Issue:4

    Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl

1971
Parkinsonism and dopa.
    The New Zealand medical journal, 1969, Volume: 69, Issue:444

    Topics: Dihydroxyphenylalanine; Humans; New Zealand; Orphenadrine; Parkinson Disease; Parkinson Disease, Postencephalitic; Trihexyphenidyl

1969
Antiparkinsonism drugs.
    The Medical letter on drugs and therapeutics, 1965, Mar-12, Volume: 7, Issue:6

    Topics: Antidepressive Agents; Atropine; Diphenhydramine; Humans; Orphenadrine; Parasympatholytics; Parkinson Disease; Promethazine; Scopolamine; Trihexyphenidyl

1965
[Indications and modes of administration of fluphenazine enanthate].
    Annales medico-psychologiques, 1967, Volume: 125, Issue:2

    Topics: Fluphenazine; Humans; Injections; Orphenadrine; Parasympathomimetics; Psychotic Disorders; Trihexyphenidyl; Tropanes

1967
Adverse effects of anticholinergic antiparkinsonian drugs in tardive dyskinesia. An investigation of mechanism.
    Neuropsychobiology, 1980, Volume: 6, Issue:2

    Topics: Adult; Aged; Antiparkinson Agents; Antipsychotic Agents; Benztropine; Dopamine; Dyskinesia, Drug-Induced; Female; Growth Hormone; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Prolactin; Sex Factors; Thyrotropin; Trihexyphenidyl

1980
Anticholinergic drug abuse: a common problem?
    British medical journal (Clinical research ed.), 1984, Sep-08, Volume: 289, Issue:6445

    Topics: Adult; Biperiden; Female; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Schizophrenia; Substance-Related Disorders; Trihexyphenidyl

1984
Impaired cognitive shifting in parkinsonian patients on anticholinergic therapy.
    Neuropsychologia, 1993, Volume: 31, Issue:4

    Topics: Aged; Cognition; Female; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Parkinson Disease; Psychiatric Status Rating Scales; Trihexyphenidyl

1993
Misuse of anticholinergic drugs by people with serious mental illness.
    Psychiatric services (Washington, D.C.), 2000, Volume: 51, Issue:7

    Topics: Adult; Benztropine; Female; Humans; Illicit Drugs; Male; Mental Disorders; Muscarinic Antagonists; New South Wales; Orphenadrine; Prevalence; Procyclidine; Substance-Related Disorders; Trihexyphenidyl

2000
PARKINSON'S DISEASE.
    Physiotherapy, 1963, Dec-10, Volume: 49

    Topics: Amitriptyline; Dextroamphetamine; Humans; Imipramine; Muscle Relaxants, Central; Neurosurgery; Orphenadrine; Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Pathology; Stereotaxic Techniques; Trihexyphenidyl

1963
PARKINSONISM: AETIOLOGY AND TREATMENT.
    London Clinic medical journal, 1964, Volume: 5

    Topics: Carbon Monoxide Poisoning; Craniocerebral Trauma; Drug Therapy; Encephalitis; Intracranial Arteriosclerosis; Manganese; Neurosurgery; Neurosurgical Procedures; Orphenadrine; Parasympatholytics; Parkinsonian Disorders; Reserpine; Stereotaxic Techniques; Syphilis; Toxicology; Trihexyphenidyl

1964
ORPHENADRINE IN THE TREATMENT OF PARKINSON'S DISEASE.
    Current medicine and drugs, 1964, Volume: 5, Issue:1

    Topics: Biomedical Research; Geriatrics; Orphenadrine; Parkinson Disease; Parkinsonian Disorders; Pharmacology; Toxicology; Trihexyphenidyl

1964
THE DISORDERED MOVEMENT IN PARKINSONISM AND THE EFFECT OF DRUG TREATMENT.
    Bulletin of the Johns Hopkins Hospital, 1964, Volume: 115

    Topics: Atropine; Dextroamphetamine; Diphenhydramine; Drug Therapy; Geriatrics; Humans; Kinetics; Motor Skills; Movement Disorders; Orphenadrine; Parasympatholytics; Parkinsonian Disorders; Reaction Time; Trihexyphenidyl

1964
A COMPARATIVE STUDY OF TRIHEXYPHENIDYL (ARTANE) AND ORPHENADRINE (DISIPAL) IN THE TREATMENT OF GERIATRIC PARKINSONISM.
    Journal of the American Geriatrics Society, 1965, Volume: 13

    Topics: Biomedical Research; Drug Therapy; Geriatrics; Orphenadrine; Parkinsonian Disorders; Toxicology; Trihexyphenidyl

1965