trihexyphenidyl has been researched along with clozapine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Korf, J; Westerink, BH | 1 |
| Bartholini, G; Keller, HH; Pletscher, A | 1 |
| Cheney, DL; Costa, E; Racagni, G; Trabucchi, M | 1 |
| Bunney, BS; Chiodo, LA | 1 |
| Gardner, EL; Paredes, W; Walker, LS | 1 |
| de Leon, J; Simpson, GM; Stanilla, JK; White, AO | 1 |
| Brown, D; Factor, SA; Molho, ES; Podskalny, GD | 1 |
| Modai, I; Poyurovsky, M; Weizman, A | 1 |
| Fowler, SC; Stanford, JA | 1 |
| Adlersberg, S; Gonen, N; Mester, R; Rosen, L; Spivak, B; Weizman, A | 1 |
| Baker, LE; Meltzer, HY; Prus, AJ | 1 |
| Caine, SB; Fink-Jensen, A; Thomsen, M; Wess, J; Woldbye, DP; Wörtwein, G | 1 |
| Pehrson, AL; Philibin, SD; Porter, JH; Prus, AJ; Vunck, SA; Wood, JT | 1 |
| Aggarwal, A; Garg, A; Jiloha, RC | 1 |
| Khanande, RV; Praharaj, SK; Sarkhel, S; Sinha, VK | 1 |
| Chen, YS; Gong, FJ; Liang, C; Wang, R; Wang, W; Wu, ZP; Zhang, RS; Zhang, YR; Zheng, SQ | 1 |
| Ding, FF; Guo, H; Huang, ZL; Jiang, JB; Liu, CF; Qu, WM; Yang, SR; Zhou, JC | 1 |
1 review(s) available for trihexyphenidyl and clozapine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for trihexyphenidyl and clozapine
| Article | Year |
|---|---|
Trihexyphenidyl treatment of clozapine-induced hypersalivation.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Male; Muscarinic Antagonists; Schizophrenia; Sialorrhea; Trihexyphenidyl | 1997 |
18 other study(ies) available for trihexyphenidyl and clozapine
| Article | Year |
|---|---|
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Atropine; Brain; Brain Chemistry; Clozapine; Corpus Striatum; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Male; Morphine; Oxotremorine; Phenylacetates; Physostigmine; Pimozide; Probenecid; Rats; Substantia Nigra; Trihexyphenidyl | 1975 |
Drug-induced changes of dopamine turnover in striatum and limbic system of the rat.
Topics: Animals; Brain Chemistry; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Limbic System; Male; Oxotremorine; Rats; Species Specificity; Stimulation, Chemical; Tranquilizing Agents; Trihexyphenidyl | 1975 |
In vivo actions of clozapine and haloperidol on the turnover rate of acetylcholine in rat striatum.
Topics: Animals; Apomorphine; Benztropine; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Drug Interactions; Humans; Kinetics; Male; Motor Activity; Oxotremorine; Rats; Receptors, Drug; Stereotyped Behavior; Trihexyphenidyl | 1976 |
Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons.
Topics: Anesthetics; Animals; Antipsychotic Agents; Biomechanical Phenomena; Chloral Hydrate; Clozapine; Dibenzazepines; Dioxanes; Dopamine; Drug Combinations; Haloperidol; Idazoxan; Male; Mesencephalon; Neurons; Prazosin; Rats; Rats, Inbred Strains; Trihexyphenidyl | 1985 |
Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat.
Topics: Animals; Brain; Cholinergic Antagonists; Clozapine; Dopamine; Electric Stimulation; Haloperidol; Limbic System; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Reward; Trihexyphenidyl; Up-Regulation | 1993 |
Anticholinergics to treat clozapine withdrawal.
Topics: Adult; Clozapine; Female; Humans; Male; Schizophrenia; Substance Withdrawal Syndrome; Trihexyphenidyl | 1994 |
The effect of dancing on dystonia.
Topics: Adult; Antipsychotic Agents; Bromocriptine; Clozapine; Dancing; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Dystonia; Humans; Male; Psychotic Disorders; Trihexyphenidyl; Vitamin E | 1996 |
Trihexyphenidyl as a possible therapeutic option in clozapine-induced nocturnal enuresis.
Topics: Adult; Antipsychotic Agents; Clozapine; Enuresis; Humans; Male; Muscarinic Antagonists; Sialorrhea; Trihexyphenidyl | 1996 |
Similarities and differences between the subchronic and withdrawal effects of clozapine and olanzapine on forelimb force steadiness.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Tolerance; Forelimb; Male; Muscarinic Antagonists; Olanzapine; Pirenzepine; Quipazine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Tremor; Trihexyphenidyl | 1997 |
Discriminative stimulus properties of 1.25 and 5.0 mg/kg doses of clozapine in rats: examination of the role of dopamine, serotonin, and muscarinic receptor mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Butyrophenones; Clozapine; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Fluorobenzenes; Generalization, Stimulus; Haloperidol; Male; Muscarinic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trihexyphenidyl | 2004 |
Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5 muscarinic acetylcholine receptor knockout mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cocaine; Dextroamphetamine; Dopamine Agonists; Female; Genotype; Haloperidol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Muscarinic Agonists; Receptors, Muscarinic; Reflex; Reflex, Startle; Schizophrenia; Trihexyphenidyl | 2007 |
The role of M1 muscarinic cholinergic receptors in the discriminative stimulus properties of N-desmethylclozapine and the atypical antipsychotic drug clozapine in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Trihexyphenidyl | 2009 |
Trihexyphenidyl (benzhexol) in clozapine-induced nocturnal enuresis and sialorrhea.
Topics: Amitriptyline; Antipsychotic Agents; Clozapine; Humans; Male; Muscarinic Antagonists; Nocturnal Enuresis; Schizophrenia; Sialorrhea; Trihexyphenidyl; Young Adult | 2009 |
Complete resolution of clozapine-induced sialorrhea with low dose trihexyphenidyl.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Male; Muscarinic Antagonists; Sialorrhea; Treatment Outcome; Trihexyphenidyl | 2010 |
[Simultaneous determination of trihexyphenidyl, chlorpromazine and clozapine in blood by GC-MS].
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Clozapine; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Solvents; Trihexyphenidyl | 2011 |
Trihexyphenidyl increases delta activity in non-rapid eye movement sleep without impairing cognitive function in rodent models.
Topics: Animals; Choline O-Acetyltransferase; Clozapine; Cognition; Electroencephalography; Eye Movements; Humans; Mice; Oxides; Rodentia; Sleep; Trihexyphenidyl | 2022 |