Page last updated: 2024-08-16

trihexyphenidyl and biperiden

trihexyphenidyl has been researched along with biperiden in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199022 (48.89)18.7374
1990's14 (31.11)18.2507
2000's6 (13.33)29.6817
2010's3 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, MH; Acree, WE; Ibrahim, A1
Bhattacharjee, AK; Evans, SA; Gordon, RK; Pervitsky, D; Pomponio, JW1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Spiteller, G; Stock, B1
Jellinek, T1
Parkenberg, H1
Suitsu, N1
Onodera, K; Shinoda, H1
di Costanzo, E; Schifano, F1
Ichimura, F; Nakashima, E; Yamana, T; Yokogawa, K1
Mano, T1
Birket-Smith, E1
Jurna, I; Lanzer, G1
Bachmann, T; Jurna, I; Theres, C1
Chatten, LG; Racz, WJ1
Caffey, E; Klett, CJ1
Cole, JO; DiMascio, A; Kasparian, G; Orlov, P1
Meyer, HH1
Cole, JO; Gardos, G; Jellinek, T1
Best, NR; Maguire, J; Pullen, GP1
Kjeldaas, L1
Bessen, HA; Corre, KA; Niemann, JT1
Kehr, W1
Magnus, RV1
Caviglia, A; Cellitti, M; Di Bianco, V; Di Castro, A; Pavoncello, S1
Dequardo, JR; Tandon, R1
Linazasoro, G1
Capacio, BR; Cook, LA; Shih, TM1
Kurisaki, H; Mizuno, T; Nishiyama, K; Sakuta, M1
Gillin, JC; Shiromani, PJ; Velazquez-Moctezuma, J; Zoltoski, RK1
Liu, WF1
Ikeda, K; Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Shibata, M; Suzuki, A; Yasui, N1
Bolaños-Badillo, E; González-Sánchez, H; Prado-Alcalá, RA; Quirarte, GL; Roldán, G1
Ichimura, F; Ishizaki, J; Nakashima, E; Ohkuma, S; Yokogawa, K2
Kihira, K; Kimura, Y; Kitaura, T; Ohue, M1
Giordani, B; Guthrie, SK; Manzey, L; Scott, D; Tandon, R1
Arakawa, K; Hayashi, Y; Inoue, I; Kira, J; Kuwabara, Y; Nakagawa, M; Ohyagi, Y; Taniwaki, T; Yamada, T1
Miyaoka, H; Obata, M; Suzuki, E; Yoshida, Y1
MILLER, V1
BRANDT, G; BRANDT, W1
LERNER, PF1
Hadidi, KA1
Aas, P; Enger, S; Myhrer, T1
Camargos, S; Cardoso, F; Lees, AJ; Singleton, A1

Reviews

2 review(s) available for trihexyphenidyl and biperiden

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[A case of amoxapine-induced tardive dystonia successfully treated with a low dose anti-cholinergic agent].
    Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:4

    Topics: Amoxapine; Antidepressive Agents, Tricyclic; Biperiden; Cholinergic Antagonists; Drug Therapy, Combination; Dystonia; Humans; Male; Middle Aged; Trihexyphenidyl

2000

Trials

5 trial(s) available for trihexyphenidyl and biperiden

ArticleYear
[A computer-assisted EEG study on psychotropic properties of antiparkinsonian drugs].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1992, Volume: 94, Issue:3

    Topics: Amantadine; Antiparkinson Agents; Biperiden; Bromocriptine; Electroencephalography; Glycolates; Humans; Levodopa; Male; Psychotropic Drugs; Thiophenes; Trihexyphenidyl

1992
Evaluating the long-term need for antiparkinson drugs by chronic schizophrenics.
    Archives of general psychiatry, 1972, Volume: 26, Issue:4

    Topics: 1-Propanol; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Biperiden; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Evaluation Studies as Topic; Humans; Male; Middle Aged; Movement Disorders; Parasympatholytics; Piperidines; Procyclidine; Pyrrolidines; Schizophrenia; Tranquilizing Agents; Trihexyphenidyl; Tropanes

1972
A comparison of biperiden hydrochloride (Akineton) and benzhexol (Artane) in the treatment of drug-induced Parkinsonism.
    The Journal of international medical research, 1980, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Biperiden; Female; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Piperidines; Trihexyphenidyl

1980
No effect of the anticholinergic drugs trihexyphenidyl and biperiden on the plasma concentrations of bromperidol and its reduced metabolite.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:2

    Topics: Adult; Biperiden; Drug Interactions; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia; Trihexyphenidyl

1997
Comparison of central and peripheral pharmacologic effects of biperiden and trihexyphenidyl in human volunteers.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Biperiden; Double-Blind Method; Female; Hemodynamics; Humans; Male; Mental Recall; Muscarinic Antagonists; Placebos; Psychomotor Performance; Salivation; Trihexyphenidyl

2000

Other Studies

38 other study(ies) available for trihexyphenidyl and biperiden

ArticleYear
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
    Bioorganic & medicinal chemistry, 2013, May-01, Volume: 21, Issue:9

    Topics: Atropine; Computer Simulation; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Receptor, Muscarinic M1; Structure-Activity Relationship

2013
[Metabolism of antiparkinson drugs. An example of competitive hydroxylation].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:4

    Topics: Adult; Antiparkinson Agents; Biotransformation; Biperiden; Humans; Hydroxylation; Male; Mass Spectrometry; Piperidines; Structure-Activity Relationship; Trihexyphenidyl

1979
Mood elevating effect of trihexyphenidyl and biperiden in individuals taking antipsychotic medication.
    Diseases of the nervous system, 1977, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Emotions; Euphoria; Female; Hallucinations; Humans; Male; Middle Aged; Piperidines; Schizophrenia; Trihexyphenidyl

1977
[Treatment of parkinsonism].
    Ugeskrift for laeger, 1976, Apr-26, Volume: 138, Issue:18

    Topics: Amantadine; Benztropine; Biperiden; Humans; Levodopa; Orphenadrine; Parkinson Disease; Procyclidine; Trihexyphenidyl

1976
Pharmacological characteristics of catalepsy induced by intracerebroventricular administration of histamine in mice: the importance of muscarinic step in central cholinergic neurons.
    Agents and actions, 1991, Volume: 33, Issue:1-2

    Topics: Amantadine; Animals; Atropine; Biperiden; Bromocriptine; Catalepsy; Histamine; Injections, Intraventricular; Levodopa; Male; Mice; Neurons; Promethazine; Receptors, Muscarinic; Scopolamine; Trihexyphenidyl

1991
Excessive use of anticholinergic drugs in a sub-sample of Italian schizophrenics.
    International journal of clinical pharmacology, therapy, and toxicology, 1991, Volume: 29, Issue:5

    Topics: Adult; Biperiden; Female; Humans; Italy; Male; Middle Aged; Orphenadrine; Parasympatholytics; Patient Compliance; Procyclidine; Retrospective Studies; Sampling Studies; Schizophrenia; Trihexyphenidyl

1991
Simultaneous microdetermination of biperiden, haloperidol, and trihexyphenidyl in plasma and its application to pharmacokinetic analysis after concomitant intravenous administration of the drugs to rabbits.
    Chemical & pharmaceutical bulletin, 1985, Volume: 33, Issue:10

    Topics: Animals; Biperiden; Chromatography, Gas; Haloperidol; Injections, Intravenous; Kinetics; Piperidines; Rabbits; Trihexyphenidyl

1985
[Dyskinesia induced by anticholinergic drugs--electrophysiological analysis].
    Rinsho shinkeigaku = Clinical neurology, 1974, Volume: 14, Issue:3

    Topics: Aged; Benztropine; Biperiden; Electromyography; Female; Humans; Male; Middle Aged; Movement Disorders; Parasympatholytics; Parkinson Disease; Phenothiazines; Procyclidine; Trihexyphenidyl

1974
Abnormal involuntary movements induced by anticholinergic therapy.
    Acta neurologica Scandinavica, 1974, Volume: 50, Issue:6

    Topics: Aged; Biperiden; Dibenzazepines; Female; Humans; Mastication; Middle Aged; Movement Disorders; Orphenadrine; Parasympatholytics; Parkinson Disease; Phenothiazines; Procyclidine; Tremor; Trihexyphenidyl

1974
Inhibition of the effect of reserpine on motor control by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 262, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Cyclopentanes; Depression, Chemical; Dihydroxyphenylalanine; Methamphetamine; Motor Activity; Motor Neurons; Movement Disorders; Parasympathomimetics; Phenytoin; Piperidines; Rats; Reserpine; Spinal Cord; Sympathomimetics; Trihexyphenidyl

1969
The effect of physostigmine and tetrabenazine on spinal motor control and its inhibition by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Methamphetamine; Motor Neurons; Movement Disorders; Parasympatholytics; Phenytoin; Physostigmine; Piperidines; Rats; Reserpine; Spinal Cord; Spinal Nerves; Tetrabenazine; Trihexyphenidyl

1969
Quantitative determination of some synthetic antiparkinsonism agents.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:1

    Topics: Amines; Biperiden; Borates; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chloroform; Colorimetry; Indicators and Reagents; Methods; Parasympatholytics; Perchlorates; Phenethylamines; Phenols; Procyclidine; Trihexyphenidyl

1968
Withdrawal of antiparkinson drugs.
    Archives of general psychiatry, 1971, Volume: 25, Issue:5

    Topics: Biperiden; Butyrophenones; Female; Humans; Male; Parasympatholytics; Parkinson Disease; Psychotic Disorders; Recurrence; Thiothixene; Time Factors; Tranquilizing Agents; Trihexyphenidyl

1971
[On the question of possible irreversible disorders due to psychopharmacotherapy].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1966, Volume: 208, Issue:4

    Topics: Adult; Autonomic Nervous System; Biperiden; Butyrophenones; Central Nervous System; Chlorpromazine; Extrapyramidal Tracts; Humans; Male; Movement Disorders; Phenothiazines; Plants, Medicinal; Promethazine; Psychotic Disorders; Rauwolfia; Tranquilizing Agents; Trihexyphenidyl

1966
Adverse effects of antiparkinson drug withdrawal.
    The American journal of psychiatry, 1981, Volume: 138, Issue:12

    Topics: Antiparkinson Agents; Antipsychotic Agents; Benztropine; Biperiden; Double-Blind Method; Drug Therapy, Combination; Humans; Schizophrenia; Substance Withdrawal Syndrome; Trihexyphenidyl

1981
Anticholinergic drug abuse: a common problem?
    British medical journal (Clinical research ed.), 1984, Sep-08, Volume: 289, Issue:6445

    Topics: Adult; Biperiden; Female; Humans; Male; Middle Aged; Orphenadrine; Parasympatholytics; Schizophrenia; Substance-Related Disorders; Trihexyphenidyl

1984
[Abuse of the antiparkinson agents biperidin and benzhexol].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1983, Aug-30, Volume: 103, Issue:24

    Topics: Biperiden; Hallucinations; Humans; Piperidines; Trihexyphenidyl

1983
Extended therapy for acute dystonic reactions.
    Annals of emergency medicine, 1984, Volume: 13, Issue:3

    Topics: Acute Disease; Adult; Benztropine; Biperiden; Diphenhydramine; Dystonia; Female; Humans; Jaw; Male; Recurrence; Trihexyphenidyl; Trismus

1984
[Drug therapy of Parkinson disease and parkinson disease-like symptoms].
    Arzneimittel-Forschung, 1981, Volume: Suppl 27

    Topics: Adenylyl Cyclases; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biperiden; Brain; Catechol O-Methyltransferase; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; In Vitro Techniques; Mice; Monoamine Oxidase; Oxotremorine; Parkinson Disease; Rats; Receptors, Dopamine; Reserpine; Trihexyphenidyl

1981
[Neurological aspects and modern trends in therapy of Parkinson's disease].
    La Clinica terapeutica, 1980, Feb-29, Volume: 92, Issue:4

    Topics: Atropine; Biperiden; Humans; Levodopa; Parasympatholytics; Parkinson Disease; Procyclidine; Trihexyphenidyl

1980
Treatment of schizophrenia with anticholinergic medications.
    The American journal of psychiatry, 1995, Volume: 152, Issue:5

    Topics: Acute Disease; Biperiden; Cholinergic Antagonists; Controlled Clinical Trials as Topic; Dopamine; Double-Blind Method; Humans; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Trihexyphenidyl

1995
Anticholinergics and dyskinesia.
    Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:6

    Topics: Aged; Biperiden; Carbidopa; Drug Combinations; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Neurologic Examination; Parkinson Disease; Tremor; Trihexyphenidyl

1994
Effects of anticholinergic-antiparkinsonian drugs on striatal neurotransmitter levels of rats intoxicated with soman.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Acetylcholine; Animals; Antiparkinson Agents; Behavior, Animal; Biperiden; Catecholamines; Cholinesterases; Corpus Striatum; Male; Neurotransmitter Agents; Parasympatholytics; Rats; Rats, Sprague-Dawley; Soman; Spinal Cord; Trihexyphenidyl

1993
Chronic dementia in Parkinson's disease treated by anticholinergic agents. Neuropsychological and neuroradiological examination.
    Advances in neurology, 1993, Volume: 60

    Topics: Aged; Biperiden; Blood Glucose; Brain; Cerebral Cortex; Dementia; Energy Metabolism; Female; Humans; Intelligence; Male; Mental Recall; Neuropsychological Tests; Parasympatholytics; Parkinson Disease; Regional Blood Flow; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Trihexyphenidyl; Wechsler Scales

1993
The relative effects of selective M1 muscarinic antagonists on rapid eye movement sleep.
    Brain research, 1993, Apr-16, Volume: 608, Issue:2

    Topics: Animals; Biperiden; Electrodes, Implanted; Electroencephalography; Electromyography; Male; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Scopolamine; Sleep, REM; Trihexyphenidyl; Wakefulness

1993
Effects of antimuscarinic antiparkinsonian drugs on brightness discrimination performance in rats.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 54, Issue:2

    Topics: Animals; Antiparkinson Agents; Biperiden; Discrimination, Psychological; Dose-Response Relationship, Drug; Light; Male; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Time Factors; Trihexyphenidyl

1996
Selective M1 muscarinic receptor antagonists disrupt memory consolidation of inhibitory avoidance in rats.
    Neuroscience letters, 1997, Jul-18, Volume: 230, Issue:2

    Topics: Animals; Avoidance Learning; Biperiden; Dose-Response Relationship, Drug; Male; Memory; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine; Trihexyphenidyl

1997
Characteristic subcellular distribution, in brain, heart and lung, of biperiden, trihexyphenidyl, and (-)-quinuclidinyl benzylate in rats.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:1

    Topics: Animals; Biperiden; Brain; Brain Chemistry; Cholinergic Agents; Heart; Lung; Male; Myocardium; Parasympatholytics; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Subcellular Fractions; Trihexyphenidyl

1998
Influence of ammonium chloride on the tissue distribution of anticholinergic drugs in rats.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:7

    Topics: Adipose Tissue; Ammonium Chloride; Animals; Biperiden; Brain; Intestinal Mucosa; Kidney; Male; Muscarinic Antagonists; Muscles; Myocardium; Rats; Rats, Wistar; Tissue Distribution; Trihexyphenidyl

1998
Amnesic effects of the anticholinergic drugs, trihexyphenidyl and biperiden: differences in binding properties to the brain muscarinic receptor.
    Brain research, 1999, Jul-10, Volume: 834, Issue:1-2

    Topics: Amnesia; Animals; Avoidance Learning; Binding, Competitive; Biperiden; Brain; Cerebral Cortex; Cholinergic Antagonists; Electroshock; Male; Membranes; Pain; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Retention, Psychology; Time Factors; Trihexyphenidyl

1999
Tardive dyskinesia with risperidone and anticholinergics.
    The American journal of psychiatry, 2002, Volume: 159, Issue:11

    Topics: Adult; Biperiden; Cholinergic Antagonists; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Neurologic Examination; Risperidone; Schizophrenia; Trihexyphenidyl

2002
THE EFFECTS OF BIPERIDEN HYDROCHLORIDE (AKINETON) IN POST-ENCEPHALITIC PARKINSONISM.
    Scottish medical journal, 1964, Volume: 9

    Topics: Biomedical Research; Biperiden; Drug Therapy; Encephalitis; Parasympatholytics; Parkinson Disease, Postencephalitic; Parkinsonian Disorders; Placebos; Toxicology; Trihexyphenidyl

1964
[Medicamentous treatment of the extrapyramidal syndrome; a contribution to the possibility of combining belladonna alkaloids with akineton].
    Deutsche medizinische Wochenschrift (1946), 1955, Jun-24, Volume: 80, Issue:25

    Topics: Atropa belladonna; Belladonna Alkaloids; Biperiden; Disease; Extrapyramidal Tracts; Gastrointestinal Agents; Humans; Parasympatholytics; Trihexyphenidyl

1955
Use of biperiden hydrochloride in Parkinson's disease.
    Southern medical journal, 1960, Volume: 53

    Topics: Biperiden; Humans; Parkinson Disease; Trihexyphenidyl

1960
Development of a screening method for the most commonly abused anticholinergic drugs in Jordan; trihexyphenidyl, procyclidine and biperiden.
    Legal medicine (Tokyo, Japan), 2004, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Biperiden; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Jordan; Male; Muscarinic Antagonists; Procyclidine; Substance Abuse Detection; Substance-Related Disorders; Trihexyphenidyl

2004
Antiparkinson drugs used as prophylactics for nerve agents: studies of cognitive side effects in rats.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:4

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Benactyzine; Biperiden; Cholinergic Antagonists; Cholinesterase Inhibitors; Cognition; Cyclopentanes; Exploratory Behavior; Male; Motor Activity; Neurotoxins; Organophosphorus Compounds; Physostigmine; Procyclidine; Rats; Rats, Wistar; Trihexyphenidyl

2008
DYT16: the original cases.
    Journal of neurology, neurosurgery, and psychiatry, 2012, Volume: 83, Issue:10

    Topics: Adolescent; Adult; Age of Onset; Anti-Dyskinesia Agents; Antiparkinson Agents; Baclofen; Biperiden; Botulinum Toxins; Carbidopa; Child; Child, Preschool; Cholinergic Antagonists; Drug Combinations; Drug Resistance; Dystonia; Dystonic Disorders; Female; Humans; Levodopa; Male; Middle Aged; Muscle Relaxants, Central; Mutation; Parkinsonian Disorders; Pedigree; Phenotype; RNA-Binding Proteins; Speech Disorders; Trihexyphenidyl; Young Adult

2012