Page last updated: 2024-08-17

trifluridine and thymidine

trifluridine has been researched along with thymidine in 126 studies

Research

Studies (126)

Timeframe	Studies, this research(%)	All Research%
pre-1990	112 (88.89)	18.7374
1990's	5 (3.97)	18.2507
2000's	6 (4.76)	29.6817
2010's	3 (2.38)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chou, TC; Gadler, H; Kalman, TI; Matulic-Adamic, J; Price, RW; Reddy, AR; Takahashi, K; Watanabe, KA	1
Meyer, RB; Nakayama, C; Saneyoshi, M; Santi, DV; Ueda, T; Wataya, Y	1
Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Van Rompaey, P; Vanheusden, V	1
Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE	1
Agrawal, B; Kumar, R; Mak, M; Srivastav, NC; Tyrrell, DL	1
Clough, DW; Parkhurst, JR; Wigdahl, BL	1
Cantell, K; Neumann-Haefelin, D; Sundmacher, R	1
Balboni, PG; Barbanti-Brodano, G; de Vries, J; Fiume, L; Mattioli, A; Tognon, M; Wieland, T	1
Pavan-Langston, D	1
Eiferman, RA; Lennette, DA	1
Alpren, TV; Charlin, RE; Hyndiuk, RA; Schultz, RO	1
Charlton, RK; Grisham, JW; Kaufman, DG; Smith, GJ	1
Sundmacher, R	2
Kaufman, HE; McNeill, JI	1
Campbell, R; Lass, J; Pavan-Langston, D	1
Nelson, DJ; Pavan-Langston, D	1
Adair, GM; Carver, JH	1
Olsen, EG	1
Coster, DJ; Jones, BR; McGill, JI	1
Currie, V; Kempin, S; Warrell, RP; Young, C	1
Bigar, F	1
Beirnaert, V; François, J; Van Oye, R	1
O'Brien, WJ	1
Baker, MS; Benedict, WF; Heidelberger, C; Jones, PA; Mondal, S; Rapp, U	1
Heidelberger, C	1
Danenberg, PV; Heidelberger, C; Parkhurst, JR	1
Parkhurst, JR; Wigdahl, BL	2
Blake, J; Browne, M	1
Edelhauser, HF; O'Brien, WJ	1
Holtmann, HW; Stein, HJ	1
Foster, CS; Pavan-Langston, D	1
Patterson, A; Travers, JP	1
Arentsen, JJ; Eiferman, RA; Laibson, PR; Mazzanti, WD	1
Coster, DJ; Fraunfelder, FT; Jones, BR; McGill, JI; McKinnon, JR	1
Hyndiuk, RA; Leibsohn, JM; Seideman, S	1
Armstrong, DK; Davidson, NE; Isaacs, JT; Ottaviano, YL	1
Bourne, WM; Shearer, DR	1
Berry, JP; Boumati, P; Cavellier, JF; Escaig, F; Lespinats, G; Tlouzeau, S	1
de la Cuadra, J; Millán-Parrilla, F	1
Amacher, DE; Turner, GN	1
Applegate, ML; Hozier, JC; Moore, MM	1
Nakagawa, H; Uchida, Y	1
Chabala, J; Galle, P; Hallegot, P; Legeais, JM; Levi-Setti, R; Renard, G	1
Blazak, WF; Caspary, WJ; Los, FJ; Rudd, CJ	1
Alkan, HM; Khoobehi, B; Mani, H; Peyman, GA; Schulman, JA; Tawakol, ME	1
Kobayashi, K; Matsumoto, H; Noguchi, K; Ueda, T; Yamashita, J; Yasumoto, M	1
Isaacs, JT; Kyprianou, N	1
Berry, JP; Boumati, P; Cavellier, JF; Escaig, F; Galle, P; Lespinats, G; Tlouzeau, S	1
Haruta, Y; Hill, JM; Kaufman, HE; Reidy, JJ; Rootman, DS	1
Yamane, A	1
Bodor, N; Brey, W; el Koussi, A; Houck, HJ; Loftsson, T; Raad, I; Rand, KH; Rocca, J	1
De Clercq, E; Huyghe, P; Maudgal, PC	1
Gailhofer, G; Ludvan, M; Posawetz-Kresbach, M	1
Ayisi, NK; Babiuk, LA; Gupta, SV	1
Bodor, N; el Koussi, AA; Gildersleeve, N; Houck, H; Miyake, A; Raad, I; Rand, KH	1
Araullo-Cruz, T; Blough, HA; Cheng, KP; Gordon, YJ; Johnson, BJ; Romanowski, E	1
Allen, KL; Blazak, WF; Caspary, WJ; Galperin, I; Mitchell, AD; Rudd, CJ; Stewart, BE	1
Bewsey, BJ; Oberly, TJ; Probst, GS	1
Behrens-Baumann, W; Quentin, CD; Vogel, M	1
Fantes, F; Hajek, AS; Mallick, KS; Parrish, RK; Rivera, AH	1
Bowers, L; Brown, A; Caspary, WJ; McGregor, D; Myhr, B; Riach, C	1
Buechi, ER; Herbort, CP; Matter, M	1
Mimura, Y; Naito, T; Shiota, H	1
Fiscella, R; Kao, G; Nikoleit, J; Pang, MP; Peyman, GA	1
Matsumoto, H; Takeda, S; Terada, T; Unemi, N; Yamashita, J; Yasumoto, M	1
Alkan, H; Fiscella, R; Khoobehi, B; Liu, KR; Peyman, GA	1
Matulic-Adamic, J; Watanabe, KA	1
Dunkel, EC; Geary, PA; Imperia, PS; Lass, JH; Lazarus, HM; Pavan-Langston, D	1
Bodor, N; el-Koussi, A	1
Benedict, WF; Heidelberger, C; Peterson, AR	1
Udell, IJ	1
Cohen, EJ; Dreizen, NG; Galentine, PG; Laibson, PR; Parlato, CJ; Sakauye, CM	1
Batson, AG; Clive, D; Howard, BE; Moore, MM; Turner, NT	1
Batson, AG; Clive, D; Howard, BE; Hozier, JC; Moore, MM; Sawyer, J; Turner, NT	1
Maudgal, PC; Missotten, L; Molemans, M; Vrijghem, JC	1
Herbort, CP; Matter, M	2
Cox, SH; Schoen, RC; Wagner, RP	1
Balansard, G; Elias, R; Schwadrohn, G; Vidal, E	1
Chastel, C; Colin, J	1
Chastel, C; Colin, J; Volant, A	1
Jones, MF	1
Zirm, M	1
Cantell, K; de Koning, EW; van Bijsterveld, OP	2
Annel, M; de Miranda, P; Kingham, JD; Poirier, RH	1
Burkhardt, U; Wigand, R	1
Darby, G; Field, H; McMillan, A	1
Burns, WH; Saral, R; Stuart, RK; Wingard, JR	1
Avery, GS; Brogden, RN; Carmine, AA; Heel, RC; Speight, TM	1
Cheung, KS; Lang, DJ	1
Kelley, E; Spector, SA; Tyndall, M	1
Kit, S; Qavi, H	1
Maudgal, PC; Missotten, L; Van Damme, B	1
Fischer, PH; Kawahara, R; Murphy, DG	1
Denis, J; Hoang-Xuan, T; Pouliquen, Y; Renard, G	1
Cantell, K; Mattes, A; Sundmacher, R	1
Nesburn, AB; Trousdale, MD	1
Denis, J; Frot, P; Hoang-Xuan, T; Pouliquen, Y	1
Lepoff, NJ; Lowe, GH; Maguen, E; Nesburn, AB	1
Clark, DS; Gaede, P; McKeough, M; Robertson, F; Spruance, SL; Sugibayashi, K	1
Post, H; Van Bijsterveld, OP	1
Gilbert, P; Work, K	1
Danenberg, PV; Heidelberger, C; Sarrif, AM; Tone, H	1
Bartl, G; Fellinger, C	1
Sie, SH	1
Berry, DH; Cangir, A; Crist, W; Nitschke, R	1
Amacher, DE; Paillet, SC	1
Craandijk, A; la Lau, C; Lamers, WR; Mierlobensteyn, T; Oosterhuis, JA; Renardel de Lavalette, JG; van Rij, G; Versteeg, J	2
Cirkel, PK; van Ketel, WG	2
Batson, AG; Clive, D; Howard, BE; Johnson, KO; Moore-Brown, MM	1
De Clercq, E; Descamps, J; Maudgal, PC; Missotten, L; Wijnhoven, J	1
Craandijk, A; la Lau, C; Lamers, WP; Oosterhuis, JA; Renardel de Lavalette, JG; van Rij, G; Versteeg, J	1
Jones, WL	1
Smith, G	1
Asao, T; Emura, T; Fukushima, M; Kazuno, H; Suzuki, N; Tada, Y; Yamada, Y; Yano, S	1
Comijn, EM; Fukushima, M; Peters, GJ; Temmink, OH	1
Emura, T; Fujioka, A; Fukushima, M; Ohshimo, H; Suzuki, N	1
de Bruin, M; Emura, T; Fukushima, M; Peters, GJ; Temmink, OH	1
Komuro, M; Kuwata, K; Nagayama, S; Ohta, S; Okayama, T; Yoshisue, K	1
Cheng, TF; Muldoon-Jacobs, K; Patton, GW	1

Reviews

3 review(s) available for trifluridine and thymidine

Article	Year
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism. Basic life sciences, 1985, Volume: 31 Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine	1985
Trifluridine: a review of its antiviral activity and therapeutic use in the topical treatment of viral eye infections. Drugs, 1982, Volume: 23, Issue:5 Topics: Adenoviridae Infections; Animals; Antiviral Agents; Eye; Eye Diseases; Humans; Keratitis; Keratitis, Dendritic; Kinetics; Thymidine; Trifluridine; Virus Diseases	1982
Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies. Cancer science, 2007, Volume: 98, Issue:6 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Clinical Trials as Topic; Drug Combinations; Drug Delivery Systems; Drug Resistance, Neoplasm; Forecasting; Gastrointestinal Neoplasms; Humans; Pyrimidines; Pyrrolidines; Thymidine; Thymine; Trifluridine; Uracil	2007

Trials

22 trial(s) available for trifluridine and thymidine

Article	Year
Combination therapy of dendritic keratitis with trifluorothymidine and interferon. Lancet (London, England), 1978, Sep-23, Volume: 2, Issue:8091 Topics: Drug Therapy, Combination; Humans; Interferons; Keratitis, Dendritic; Thymidine; Trifluridine	1978
Current trends in therapy of ocular herpes simplex: experimental and clinical studies. Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie, 1979, Volume: 38 Topics: Animals; Arabinonucleotides; Clinical Trials as Topic; Cornea; Guanine; Humans; Idoxuridine; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Thymidine; Trifluridine; Vidarabine; Vidarabine Phosphate	1979
[Trifluorothymidin-prophylaxis of dendritic keratitis in steroid-treated herpetic keratouveitis (author's transl)]. Klinische Monatsblatter fur Augenheilkunde, 1978, Volume: 173, Issue:4 Topics: Clinical Trials as Topic; Dexamethasone; Double-Blind Method; Drug Evaluation; Humans; Keratitis, Dendritic; Ophthalmic Solutions; Thymidine; Trifluridine; Uveitis	1978
Treatment of amoeboid herpetic ulcers with adenine arabinoside or trifluorothymidine. The British journal of ophthalmology, 1979, Volume: 63, Issue:6 Topics: Corneal Ulcer; Humans; Keratitis, Dendritic; Thymidine; Time Factors; Trifluridine; Vidarabine	1979
Trifluorothymidine and idoxuridine therapy of ocular herpes. American journal of ophthalmology, 1977, Volume: 84, Issue:6 Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Clinical Trials as Topic; Corneal Ulcer; Evaluation Studies as Topic; Female; Glucocorticoids; Humans; Idoxuridine; Keratitis, Dendritic; Male; Middle Aged; Thymidine; Time Factors; Trifluridine	1977
Double controlled comparison of IDU and trifluorothymidine in thirty-three patients with superficial herpetic keratitis. Transactions of the American Ophthalmological Society, 1977, Volume: 75 Topics: Acute Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Idoxuridine; Keratitis, Dendritic; Male; Thymidine; Trifluridine	1977
Clinical evaluation of adenine arabinoside and trifluorothymidine in the treatment of corneal ulcers caused by herpes simplex virus. The Journal of infectious diseases, 1976, Volume: 133 Suppl Topics: Administration, Topical; Clinical Trials as Topic; Corneal Ulcer; Drug Evaluation; Humans; Keratitis, Dendritic; Ointments; Ophthalmic Solutions; Purine Nucleosides; Recurrence; Thymidine; Trifluridine; Vidarabine; Wound Healing	1976
[Acyclovir versus trifluorothymidine in the therapy of stromal herpes keratitis]. Klinische Monatsblatter fur Augenheilkunde, 1986, Volume: 189, Issue:4 Topics: Acyclovir; Adult; Aged; Child, Preschool; Clinical Trials as Topic; Corneal Stroma; Cortisone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Random Allocation; Thymidine; Trifluridine	1986
Blunt spatula debridement and trifluorothymidine in epithelial herpetic keratitis. Current eye research, 1987, Volume: 6, Issue:1 Topics: Clinical Trials as Topic; Debridement; Drug Tolerance; Follow-Up Studies; Humans; Keratitis, Dendritic; Thymidine; Trifluridine	1987
Role of débridement and trifluridine (trifluorothymidine) in herpes simplex dendritic keratitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:5 Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Debridement; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Thymidine; Trifluridine	1985
Combined treatment of herpetic dendritic keratitis with blunt spatula debridement and trifluorothymidine. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1985, Volume: 191, Issue:4 Topics: Adult; Aged; Antiviral Agents; Clinical Trials as Topic; Combined Modality Therapy; Debridement; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Prospective Studies; Thymidine; Time Factors; Trifluridine; Wound Healing	1985
Combination therapy for dendritic keratitis with human leucocyte interferon and trifluorothymidine. The British journal of ophthalmology, 1982, Volume: 66, Issue:8 Topics: Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Interferons; Keratitis, Dendritic; Male; Thymidine; Time Factors; Trifluridine	1982
[Combination interferon-trifluorothymidine in the treatment of herpetic keratitis]. Bulletins et memoires de la Societe francaise d'ophtalmologie, 1982, Volume: 94 Topics: Acyclovir; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Interferons; Keratitis, Dendritic; Male; Thymidine; Trifluridine	1982
Combination therapy for dendritic keratitis. High-titer alpha-interferon and trifluridine. Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:4 Topics: Drug Therapy, Combination; Humans; Interferon Type I; Keratitis, Dendritic; Thymidine; Trifluridine	1984
[Acyclovir and trifluorothymidine in herpetic kerato-uveitis. A comparative clinical study. Indications for corticoid therapy]. Journal francais d'ophtalmologie, 1984, Volume: 7, Issue:2 Topics: Acyclovir; Adrenal Cortex Hormones; Clinical Trials as Topic; Corneal Ulcer; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Random Allocation; Thymidine; Trifluridine; Uveitis; Uveitis, Anterior	1984
Trifluorothymidine versus adenine arabinoside in the treatment of herpes simplex keratitis. The British journal of ophthalmology, 1980, Volume: 64, Issue:1 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Thymidine; Time Factors; Trifluridine; Vidarabine	1980
Trifluridine (viroptic) for herpetic keratitis. The Medical letter on drugs and therapeutics, 1980, May-30, Volume: 22, Issue:11 Topics: Antiviral Agents; Clinical Trials as Topic; Corneal Ulcer; Humans; Keratitis, Dendritic; Recurrence; Thymidine; Trifluridine	1980
Trifluorthymidine in the treatment of herpes simplex corneal ulcers. A clinical evaluation. Acta ophthalmologica, 1980, Volume: 58, Issue:1 Topics: Chemical Phenomena; Chemistry; Clinical Trials as Topic; Corneal Ulcer; Herpes Simplex; Humans; Idoxuridine; Keratitis, Dendritic; Thymidine; Trifluridine	1980
Intensive chemotherapy for metastatic neuroblastoma: a Southwest Oncology Group study. Medical and pediatric oncology, 1980, Volume: 8, Issue:3 Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Infant; Male; Neoplasm Staging; Neuroblastoma; Papaverine; Thymidine; Trifluridine; Vincristine	1980
Aciclovir and trifluorothymidine in herpetic keratitis. Preliminary report of a multicentered trial. Documenta ophthalmologica. Advances in ophthalmology, 1981, Mar-20, Volume: 50, Issue:2 Topics: Acyclovir; Animals; Clinical Trials as Topic; Double-Blind Method; Guanine; Humans; Keratitis, Dendritic; Rabbits; Thymidine; Trifluridine	1981
Multicenter trial of acyclovir and trifluorothymidine in herpetic keratitis. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Antiviral Agents; Clinical Trials as Topic; Female; Guanine; Humans; Keratitis, Dendritic; Male; Thymidine; Trifluridine	1982
Acyclovir and trifluorothymidine in herpetic keratitis: a multicentre trial. The British journal of ophthalmology, 1982, Volume: 66, Issue:8 Topics: Acyclovir; Antiviral Agents; Clinical Trials as Topic; Double-Blind Method; Female; Guanine; Humans; Keratitis, Dendritic; Male; Middle Aged; Thymidine; Time Factors; Trifluridine	1982

Other Studies

101 other study(ies) available for trifluridine and thymidine

Article	Year
Nucleosides. 150. Synthesis and some biological properties of 5-monofluoromethyl, 5-difluoromethyl, and 5-trifluoromethyl derivatives of 2'-deoxyuridine and 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyluracil. Journal of medicinal chemistry, 1988, Volume: 31, Issue:8 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Division; Chemical Phenomena; Chemistry; Deoxyuridine; Encephalitis; Herpes Simplex; Nucleosides; Radionuclide Imaging; Rats; Simplexvirus; Structure-Activity Relationship; Thymidylate Synthase; Uridine	1988
Thymidine phosphorylase. Substrate specificity for 5-substituted 2'-deoxyuridines. Journal of medicinal chemistry, 1980, Volume: 23, Issue:8 Topics: Animals; Deoxyuridine; Horses; In Vitro Techniques; Models, Biological; Pentosyltransferases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Thymidine Phosphorylase	1980
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Bioorganic & medicinal chemistry letters, 2003, Sep-15, Volume: 13, Issue:18 Topics: Antitubercular Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Thymidine; Thymine Nucleotides	2003
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells	2007
Antiviral activity of 2,3'-anhydro and related pyrimidine nucleosides against hepatitis B virus. Bioorganic & medicinal chemistry letters, 2010, Nov-15, Volume: 20, Issue:22 Topics: Antiviral Agents; Hepatitis B virus; Pyrimidine Nucleosides	2010
Biological effects of 5-carboxy-2'-deoxyuridine: hydrolysis product of 5-trifluoromethyl-2'-deoxyuridine. Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:1 Topics: Antiviral Agents; Deoxyuridine; DNA; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; RNA; Temperature; Thymidine; Time Factors; Trifluridine	1978
Enhanced inhibition of virus DNA synthesis in hepatocytes by trifluorothymidine coupled to asialofetuin. FEBS letters, 1979, Jul-01, Volume: 103, Issue:1 Topics: alpha-Fetoproteins; Animals; Bone Marrow; Deoxycytidine; DNA; DNA, Viral; Ectromelia virus; Ectromelia, Infectious; Female; Hepatitis, Viral, Animal; Liver; Mice; Necrosis; Thymidine; Time Factors; Trifluridine	1979
Inhibition of adenovirus replication in vitro by trifluridine. Archives of ophthalmology (Chicago, Ill. : 1960), 1978, Volume: 96, Issue:9 Topics: Adenoviridae; Antiviral Agents; Drug Evaluation, Preclinical; Thymidine; Trifluridine; Virus Replication	1978
Trifluridine in resistant human herpetic keratitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1978, Volume: 96, Issue:10 Topics: Adolescent; Adult; Female; Humans; Keratitis, Dendritic; Male; Thymidine; Trifluridine	1978
Increased sensitivity for detection of carcinogen-induced DNA repair with the chain terminator dideoxythymidine. Biochemical and biophysical research communications, 1978, Aug-29, Volume: 83, Issue:4 Topics: Animals; Benzopyrenes; DNA Repair; Molecular Weight; Rats; Thymidine; Trifluridine	1978
Local antivirals in a herpes simplex stromal keratitis model. Archives of ophthalmology (Chicago, Ill. : 1960), 1979, Volume: 97, Issue:4 Topics: Animals; Keratitis, Dendritic; Rabbits; Thymidine; Time Factors; Trifluridine; Vidarabine	1979
Antiviral drops: comparative therapy of experimental herpes simplex keratouveitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1979, Volume: 97, Issue:6 Topics: Animals; Idoxuridine; Keratitis, Dendritic; Male; Ophthalmic Solutions; Rabbits; Thymidine; Trifluridine; Uveitis; Vidarabine	1979
Intraocular penetration of trifluridine. American journal of ophthalmology, 1979, Volume: 87, Issue:6 Topics: Aqueous Humor; Cell Membrane Permeability; Cornea; Deoxyuridine; Herpes Zoster Ophthalmicus; Humans; Iritis; Thymidine; Trifluridine	1979
Unstable, non-mutational expression of resistance to the thymidine analogue, trifluorothymidine in CHO cells. Mutation research, 1979, Volume: 60, Issue:2 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Phenotype; Thymidine; Trifluridine	1979
[Trifluorothymidine: a new virustatic for ophthalmologic use]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979, May-30, Volume: 99, Issue:15 Topics: Humans; Keratitis, Dendritic; Ophthalmic Solutions; Thymidine; Trifluridine	1979
Phase II trial of pyrazofurin, alone and in combination with trifluorothymidine, in non-Hodgkin's lymphoma. Cancer treatment reports, 1979, Volume: 63, Issue:8 Topics: Antibiotics, Antineoplastic; Drug Evaluation; Drug Therapy, Combination; Humans; Leukopenia; Lymphoma; Ribonucleosides; Stomatitis; Thrombocytopenia; Thymidine; Trifluridine	1979
Clinical experiences with trifluorothymidine in herpes simplex keratitis. Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie, 1979, Volume: 38 Topics: Animals; Corneal Transplantation; Deoxycytidine; Female; Humans; Idoxuridine; Keratitis, Dendritic; Ointments; Ophthalmic Solutions; Postoperative Complications; Pregnancy; Rabbits; Recurrence; Thymidine; Time Factors; Trifluridine	1979
[Treatment of herpetic keratitis with trifluorothymidine]. Bulletin de la Societe belge d'ophtalmologie, 1979, Volume: 183 Topics: Eye; Humans; Idoxuridine; Keratitis, Dendritic; Thymidine; Trifluridine	1979
The metabolism of trifluorothymidine by cells of the rabbit cornea. Experimental eye research, 1979, Volume: 29, Issue:6 Topics: Animals; Cell Division; Cells, Cultured; Cornea; DNA; Epithelial Cells; Epithelium; Rabbits; Thymidine; Trifluridine; Uridine	1979
Oncogenic transformation of C3H/10T1/2 clone 8 mouse embryo cells by halogenated pyrimidine nucleosides. Cancer research, 1976, Volume: 36, Issue:1 Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Idoxuridine; Mice; Oncogenic Viruses; Sarcoma, Experimental; Thymidine; Time Factors; Trifluridine	1976
On the molecular mechanism of the antiviral activity of trifluorothymidine. Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255 Topics: Antiviral Agents; DNA, Viral; Dose-Response Relationship, Drug; HeLa Cells; Humans; Idoxuridine; Keratitis, Dendritic; Molecular Weight; RNA, Messenger; RNA, Viral; Simplexvirus; Structure-Activity Relationship; Thymidine; Trifluridine; Vaccinia virus; Virus Replication	1975
Growth inhibition of cells in cultures and of vaccinia virus infected HeLa cells by derivatives of trifluorothymidine. Chemotherapy, 1976, Volume: 22, Issue:3-4 Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Depression, Chemical; HeLa Cells; Leukemia, Experimental; Liver Neoplasms; Mice; Thymidine; Trifluridine; Vaccinia virus; Virus Replication	1976
HEp-2 cell- and herpes simplex virus type 1- induced deoxythymidine kinases: inhibition by derivatives of 5-trifluoromethyl-2'-deoxyuridine. Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:3 Topics: Cells, Cultured; Simplexvirus; Thymidine; Thymidine Kinase; Trifluridine	1978
Treatment of herpetic keratitis. Documenta ophthalmologica. Advances in ophthalmology, 1977, Sep-30, Volume: 44, Issue:1 Topics: Drug Evaluation; Humans; Idoxuridine; Keratitis, Dendritic; Thymidine; Trifluridine; Vidarabine	1977
The corneal penetration of trifluorothymidine, adenine arabinoside, and idoxuridine: a comparative study. Investigative ophthalmology & visual science, 1977, Volume: 16, Issue:12 Topics: Animals; Cornea; Endothelium; Epithelium; Idoxuridine; In Vitro Techniques; Rabbits; Thymidine; Trifluridine; Vidarabine	1977
[Epithel regeneration inhibition in the treatment of Trifluorothymidin (F3TDR) (author's transl)]. Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 171, Issue:4 Topics: Animals; Cornea; Epithelium; Rabbits; Regeneration; Thymidine; Time Factors; Trifluridine	1977
A controlled trial of adenine arabinoside and trifluorothymidine in herpetic keratitis. The Journal of international medical research, 1978, Volume: 6, Issue:2 Topics: Drug Evaluation; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Thymidine; Trifluridine; Vidarabine	1978
Treatment of Vaccinial keratitis with trifluorothymidine. Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:10 Topics: Animals; Corneal Opacity; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Idoxuridine; Keratitis; Rabbits; Thymidine; Trifluridine; Vaccinia	1976
Programmed cell death in an estrogen-independent human breast cancer cell line, MDA-MB-468. Cancer research, 1992, Jun-15, Volume: 52, Issue:12 Topics: Breast Neoplasms; Cell Death; Cell Division; Cell Membrane; DNA Damage; DNA, Neoplasm; Female; Floxuridine; Humans; Microscopy, Electron, Scanning; RNA, Messenger; Thymidine; Transforming Growth Factor beta; Trifluridine; Tumor Cells, Cultured	1992
Severe ocular anterior segment ischemia after long-term trifluridine treatment for presumed herpetic keratitis. American journal of ophthalmology, 1990, Mar-15, Volume: 109, Issue:3 Topics: Anterior Eye Segment; Female; Fluorescein Angiography; Humans; Ischemia; Keratitis, Dendritic; Middle Aged; Thymidine; Time Factors; Trifluridine	1990
Intracellular localization of drugs in cultured tumor cells by ion microscopy and image processing. Histochemistry, 1990, Volume: 93, Issue:4 Topics: Bromodeoxyuridine; Cyanides; Floxuridine; Halogens; Humans; Image Processing, Computer-Assisted; Ions; Microscopy; Thymidine; Trifluridine; Tumor Cells, Cultured	1990
Allergic contact dermatitis from trifluoridine in eyedrops. Contact dermatitis, 1990, Volume: 22, Issue:5 Topics: Administration, Topical; Aged; Corneal Ulcer; Dermatitis, Contact; Drug Eruptions; Humans; Male; Ophthalmic Solutions; Patch Tests; Thymidine; Trifluridine	1990
[Therapy of herpetic diseases of the anterior eye segment]. Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:6 Topics: Acyclovir; Antiviral Agents; Drug Therapy, Combination; Herpes Zoster; Humans; Interferons; Keratitis, Dendritic; Steroids; Thymidine; Trifluridine	1985
The mutagenicity of 5-azacytidine and other inhibitors of replicative DNA synthesis in the L5178Y mouse lymphoma cell. Mutation research, 1987, Volume: 176, Issue:1 Topics: Animals; Aphidicolin; Azacitidine; Cell Line; Cytidine; Diterpenes; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Mice; Mutagens; Thymidine; Trifluridine	1987
Do trifluorothymidine-resistant mutants of L5178Y mouse lymphoma cells re-express thymidine kinase activity following 5-azacytidine treatment? Mutation research, 1988, Volume: 207, Issue:2 Topics: Animals; Azacitidine; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Thymidine; Thymidine Kinase; Translocation, Genetic; Trifluridine; Tumor Cells, Cultured	1988
[Progress in treatment of herpetic keratitis]. Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:2 Topics: Debridement; Dexamethasone; Humans; Idoxuridine; Immunotherapy; Interferons; Keratitis, Dendritic; Thymidine; Trifluridine; Vidarabine	1989
Trifluorothymidine localization in the rabbit cornea by secondary ion mass spectrometry imaging microanalysis. Current eye research, 1989, Volume: 8, Issue:9 Topics: Animals; Cornea; Iris; Mass Spectrometry; Rabbits; Thymidine; Trifluridine	1989
Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures. Mutation research, 1989, Volume: 224, Issue:2 Topics: Animals; Chromosome Aberrations; Dimethyl Sulfoxide; Hycanthone; Leukemia L5178; Leukemia, Experimental; Mice; Mutagenicity Tests; Mutagens; Mutation; Thymidine; Thymidine Kinase; Trifluridine; Tumor Cells, Cultured	1989
Toxicity and clearance of a combination of liposome-encapsulated ganciclovir and trifluridine. Retina (Philadelphia, Pa.), 1989, Volume: 9, Issue:3 Topics: Animals; Chromatography, High Pressure Liquid; Drug Carriers; Drug Combinations; Eye Enucleation; Ganciclovir; Injections; Liposomes; Rabbits; Thymidine; Time Factors; Trifluridine; Vitreous Body	1989
Studies on antitumor agents. IX. Synthesis of 3'-O-benzyl-2'-deoxy-5-trifluoromethyluridine. Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:9 Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Thymidine; Trifluridine	1989
"Thymineless" death in androgen-independent prostatic cancer cells. Biochemical and biophysical research communications, 1989, Nov-30, Volume: 165, Issue:1 Topics: Animals; Blotting, Northern; Cell Line; Cell Survival; DNA, Neoplasm; Drug Screening Assays, Antitumor; Floxuridine; Iodoacetates; Iodoacetic Acid; Male; Nucleic Acid Hybridization; Ouabain; Prostatic Neoplasms; Rats; Thymidine; Thymine; Trifluridine	1989
[Intracellular localization of halogenated drugs or molecules in cultured tumor cells. A study using ionic microscopy associated with an imaging processing system]. Bulletin du cancer, 1989, Volume: 76, Issue:8 Topics: Breast Neoplasms; Bromodeoxyuridine; Cells, Cultured; Female; Floxuridine; Humans; Image Processing, Computer-Assisted; Thymidine; Trifluridine	1989
Trifluridine decreases ocular HSV-1 recovery, but not herpetic lesions after timolol iontophoresis. Investigative ophthalmology & visual science, 1989, Volume: 30, Issue:4 Topics: Animals; Eye; Iontophoresis; Keratitis, Dendritic; Rabbits; Simplexvirus; Thymidine; Timolol; Trifluridine	1989
[Effects of 5-trifluoromethyl-2'-deoxyuridine (F3TdR) on ultrastructural localization of viral antigens in cultured cells infected with herpes simplex virus (HSV)]. Nippon Ganka Gakkai zasshi, 1989, Volume: 93, Issue:6 Topics: Animals; Antigens, Viral; Cells, Cultured; Cornea; Immunoenzyme Techniques; Microscopy, Electron; Rabbits; Simplexvirus; Thymidine; Trifluridine	1989
Trifluorothymidine: potential non-invasive diagnosis of herpes simplex infection using 19F nuclear magnetic resonance in a murine hepatitis model. Journal of virological methods, 1987, Volume: 18, Issue:4 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hepatitis, Viral, Animal; Herpes Simplex; Liver; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred CBA; Murine hepatitis virus; Simplexvirus; Thymidine; Trifluridine	1987
Experimental thymidine kinase-deficient HSV-1 keratitis: therapeutic attempts. Current eye research, 1987, Volume: 6, Issue:4 Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Drug Evaluation, Preclinical; Floxuridine; Keratitis, Dendritic; Rabbits; Thymidine; Thymidine Kinase; Trifluridine	1987
[Allergic contact eczema caused by trifluorothymidine]. Wiener klinische Wochenschrift, 1987, Mar-20, Volume: 99, Issue:6 Topics: Adolescent; Drug Eruptions; Humans; Keratitis, Dendritic; Male; Ophthalmic Solutions; Patch Tests; Thymidine; Trifluridine; Uveitis, Anterior	1987
Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses. Antiviral research, 1985, Volume: 5, Issue:1 Topics: Acyclovir; Animals; Antiviral Agents; Deoxyuridine; DNA, Viral; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Encephalitis; Foscarnet; Herpes Simplex; Male; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Rabbits; Simplexvirus; Thymidine; Trifluridine; Vidarabine; Virus Replication	1985
Potential treatment of herpes simplex virus encephalitis by brain-specific delivery of trifluorothymidine using a dihydropyridine in equilibrium pyridinium salt type redox delivery system. Journal of medical virology, 1986, Volume: 20, Issue:1 Topics: Animals; Antiviral Agents; Blood-Brain Barrier; Brain Chemistry; Chromatography, High Pressure Liquid; Encephalitis; Herpes Simplex; Oxidation-Reduction; Rats; Simplexvirus; Thymidine; Trifluridine	1986
Efficacy of glycoprotein inhibitors alone and in combination with trifluridine in the treatment of murine herpetic keratitis. Current eye research, 1986, Volume: 5, Issue:2 Topics: Animals; Conjunctivitis; Deoxy Sugars; Deoxyglucose; Drug Therapy, Combination; Eye; Keratitis, Dendritic; Male; Mice; Mice, Inbred ICR; Threonine; Thymidine; Trifluridine	1986
Chromosome analysis of trifluorothymidine-resistant L5178Y mouse lymphoma cell colonies. Environmental mutagenesis, 1986, Volume: 8, Issue:2 Topics: Animals; Cell Line; Chromosome Aberrations; Chromosome Mapping; Drug Resistance; Karyotyping; Lymphoma; Mice; Mutagens; Mutation; Thymidine; Thymidine Kinase; Translocation, Genetic; Trifluridine	1986
Thymidine kinase activity and trifluorothymidine resistance of spontaneous and mutagen-induced L5178Y cells in RPMI 1640 medium. Mutation research, 1986, Volume: 161, Issue:2 Topics: Animals; Cell Line; Culture Media; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Methylcholanthrene; Mice; Mutagenicity Tests; Neoplasm Proteins; Thymidine; Thymidine Kinase; Trifluridine; Tumor Stem Cell Assay	1986
Trifluorothymidine and 5-fluorouracil: antiproliferative activity in tissue culture. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1987, Volume: 22, Issue:1 Topics: Animals; Cell Division; Cornea; Culture Techniques; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Fluorouracil; Humans; Rabbits; Sclera; Thymidine; Trifluridine	1987
Mutagenic activity of fluorides in mouse lymphoma cells. Mutation research, 1987, Volume: 187, Issue:3 Topics: Animals; Biotransformation; Fluorides; Leukemia L5178; Male; Mice; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Potassium; Potassium Compounds; Rats; Rats, Inbred F344; Sodium Fluoride; Thymidine; Thymidine Kinase; Trifluridine	1987
Side effects in the treatment of herpetic keratitis. Current eye research, 1987, Volume: 6, Issue:1 Topics: Acyclovir; Conjunctivitis; Corneal Diseases; Dermatitis, Contact; Humans; Idoxuridine; Keratitis, Dendritic; Thymidine; Trifluridine; Vidarabine	1987
Intravitreal trifluorothymidine and retinal toxicity. Retina (Philadelphia, Pa.), 1986,Winter, Volume: 6, Issue:4 Topics: Animals; Photoreceptor Cells; Rabbits; Retina; Thymidine; Trifluridine	1986
Studies on antitumor agents. VI. Syntheses and antitumor activities of acyl derivatives of 2'-deoxy-5-trifluoromethyluridine. Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:5 Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Male; Mice; Mice, Inbred ICR; Thymidine; Trifluridine	1987
Intravitreal liposome-encapsulated trifluorothymidine in a rabbit model. Ophthalmology, 1987, Volume: 94, Issue:9 Topics: Animals; Chromatography, High Pressure Liquid; Electroretinography; Liposomes; Rabbits; Thymidine; Time Factors; Trifluridine; Vitreous Body	1987
Nucleosides. CXLIX. Novel and practical synthesis of alpha-monofluoro- and alpha,alpha-difluorothymidine (F-TDR and F2-TDR). Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:4 Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Thymidine; Trifluridine	1988
An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium. Antiviral research, 1988, Volume: 9, Issue:4 Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cornea; Deoxyuridine; Epithelium; Idoxuridine; In Vitro Techniques; Rabbits; Thymidine; Trifluridine	1988
Improved delivery through biological membranes XXV. Enhanced and sustained delivery of trifluorothymidine to the brain using a dihydropyridine in equilibrium pyridinium salt type redox delivery system. Drug design and delivery, 1987, Volume: 1, Issue:4 Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydropyridines; Half-Life; Humans; Hydrolysis; In Vitro Techniques; Male; Membranes, Artificial; Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Inbred Strains; Thymidine; Trifluridine	1987
Trifluridine-associated conjunctival cicatrization. American journal of ophthalmology, 1985, Mar-15, Volume: 99, Issue:3 Topics: Aged; Cicatrix; Conjunctival Diseases; Humans; Keratitis, Dendritic; Male; Thymidine; Trifluridine	1985
In situ analysis of trifluorothymidine-resistant (TFTr) mutants of L5178Y/TK+/- mouse lymphoma cells. Mutation research, 1985, Volume: 151, Issue:1 Topics: Agar; Animals; Bromodeoxyuridine; Cell Division; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Drug Resistance; Kinetics; Lymphoma; Mice; Mutation; Phenotype; Thymidine; Thymidine Kinase; Trifluridine	1985
Analysis of trifluorothymidine-resistant (TFTr) mutants of L5178Y/TK+/- mouse lymphoma cells. Mutation research, 1985, Volume: 151, Issue:1 Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Chromosome Aberrations; Drug Resistance; Genes; Karyotyping; Lymphoma; Mice; Mutation; Phenotype; Thymidine; Thymidine Kinase; Translocation, Genetic; Trifluridine	1985
Effect of topical acyclovir therapy on experimental herpes simplex keratouveitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:9 Topics: Acyclovir; Administration, Topical; Animals; Iritis; Keratitis, Dendritic; Ointments; Rabbits; Thymidine; Trifluridine; Uveitis	1985
Association of trifluorothymidine and débridement in herpetic dendritic keratitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:10 Topics: Debridement; Humans; Keratitis, Dendritic; Thymidine; Trifluridine	1985
A coordinate relationship between the GALK and the TK1 genes of the Chinese hamster. Biochemical genetics, 1985, Volume: 23, Issue:9-10 Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Cricetinae; Cricetulus; Fucose; Galactokinase; Genes; Genetic Linkage; Genetic Variation; Lung; Thymidine; Thymidine Kinase; Trifluridine	1985
Determination of ophthalmic therapeutic trifluorothymidine and its degradation product by reversed-phase high-performance liquid chromatography. Journal of chromatography, 1985, Nov-27, Volume: 348, Issue:1 Topics: Chromatography, High Pressure Liquid; Ophthalmic Solutions; Spectrophotometry, Ultraviolet; Thymidine; Trifluridine	1985
[Early treatment of ocular herpes simplex. Apropos of 6 cases of herpetic conjunctivitis]. Journal francais d'ophtalmologie, 1985, Volume: 8, Issue:12 Topics: Adult; Conjunctivitis, Viral; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Ophthalmic Solutions; Recurrence; Thymidine; Time Factors; Trifluridine	1985
[Trifluorothymidine therapy of corticoid-treated herpetic keratitis: experimental study in the rabbit]. Journal francais d'ophtalmologie, 1984, Volume: 7, Issue:10 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Capsid; Conjunctiva; Cornea; Corneal Stroma; Dexamethasone; Drug Therapy, Combination; Female; Glucocorticoids; Injections; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Simplexvirus; Thymidine; Trifluridine	1984
The stability of trifluorothymidine: hydrolysis in buffered aqueous solutions. The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:5 Topics: Borates; Buffers; Drug Stability; Hydrogen-Ion Concentration; Hydrolysis; Phosphates; Solutions; Thymidine; Trifluridine	1981
Immunotherapy in corneal herpes. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1980, Volume: 214, Issue:4 Topics: Drug Therapy, Combination; gamma-Globulins; Humans; Immunotherapy; Keratitis, Dendritic; Thymidine; Trifluridine	1980
Intraocular antiviral penetration. Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:12 Topics: Acyclovir; Administration, Topical; Antiviral Agents; Arabinonucleotides; Eye; Eye Diseases; Herpes Simplex; Humans; Simplexvirus; Thymidine; Trifluridine; Vidarabine Phosphate	1982
Combined chemotherapy of cutaneous herpes simplex infection of the guinea pig. Journal of medical virology, 1983, Volume: 12, Issue:2 Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Deoxyuridine; Drug Therapy, Combination; Female; Foscarnet; Guinea Pigs; Herpes Simplex; Idoxuridine; Male; Phosphonoacetic Acid; Skin Diseases, Infectious; Thymidine; Trifluridine; Vidarabine Phosphate	1983
The sensitivity of acyclovir-resistant mutants of herpes simplex virus to other antiviral drugs. The Journal of infectious diseases, 1981, Volume: 143, Issue:2 Topics: Acyclovir; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Drug Resistance, Microbial; Foscarnet; Guanine; Microbial Sensitivity Tests; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Trifluridine; Vidarabine	1981
Inhibition of mouse LM cell replication by trifluorothymidine: role of cytosolic deoxythymidine kinase. Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:5 Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytosol; DNA; L Cells; Mice; Simplexvirus; Thymidine; Thymidine Kinase; Trifluridine	1981
Activity of trifluorothymidine against cytomegalovirus. Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:3 Topics: Animals; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Cytomegalovirus; Humans; Mice; Mice, Inbred ICR; Thymidine; Trifluridine; Virus Replication	1981
Effectiveness of acycloguanosine and trifluorothymidine as inhibitors of cytomegalovirus infection in vitro. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Antiviral Agents; Cell Line; Cytomegalovirus; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Guanine; Humans; Thymidine; Trifluridine; Viral Plaque Assay	1982
Inhibition of human cytomegalovirus by trifluorothymidine. Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1 Topics: Acyclovir; Cytomegalovirus; Foscarnet; Humans; Interferon Type I; Lung; Phosphonoacetic Acid; Thymidine; Trifluridine; Virus Replication	1983
Thymidine kinase (TK) induction after infection of TK-deficient rabbit cell mutants with bovine herpesvirus type 1 (BHV-1): isolation of TK- BHV-1 mutants. Virology, 1983, Oct-30, Volume: 130, Issue:2 Topics: Animals; Arabinonucleosides; Cell Line; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Herpesvirus 1, Bovine; Mutation; Phosphorylation; Rabbits; Thymidine; Thymidine Kinase; Trifluridine	1983
Corneal epithelial dysplasia after trifluridine use. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1983, Volume: 220, Issue:1 Topics: Age Factors; Aged; Antiviral Agents; Bromodeoxyuridine; Cornea; Corneal Diseases; Epithelium; Humans; Keratitis, Dendritic; Male; Microscopy, Phase-Contrast; Thymidine; Trifluridine	1983
Preferential inhibition of 5-trifluoromethyl-2'-deoxyuridine phosphorylation by 5'-amino-5'-deoxythymidine in uninfected versus herpes simplex virus-infected cells. Molecular pharmacology, 1983, Volume: 24, Issue:1 Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Dideoxynucleosides; HeLa Cells; Herpes Simplex; Humans; Kidney; Phosphorylation; Thymidine; Thymidine Kinase; Trifluridine; Virus Replication	1983
[Comparative study of the effect of trifluorothymidine and acyclovir in herpetic anterior segmentitis]. Bulletin des societes d'ophtalmologie de France, 1983, Volume: 83, Issue:1 Topics: Acyclovir; Female; Humans; Keratitis, Dendritic; Male; Thymidine; Trifluridine; Uveitis, Anterior	1983
Human interferon alpha A or alpha D and trifluridine treatment for herpetic keratitis in rabbits. Investigative ophthalmology & visual science, 1984, Volume: 25, Issue:4 Topics: Animals; Interferon Type I; Keratitis, Dendritic; Male; Rabbits; Thymidine; Trifluridine	1984
Effect of topical trifluridine on Thygeson's superficial punctate keratitis. Ophthalmology, 1984, Volume: 91, Issue:10 Topics: Adult; Cornea; Corneal Opacity; Epithelium; Female; Humans; Keratitis; Male; Middle Aged; Ophthalmic Solutions; Thymidine; Trifluridine	1984
Effect of azone and propylene glycol on penetration of trifluorothymidine through skin and efficacy of different topical formulations against cutaneous herpes simplex virus infections in guinea pigs. Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:6 Topics: Administration, Topical; Animals; Azepines; Diffusion; Female; Guinea Pigs; Herpes Simplex; Pharmaceutical Vehicles; Propylene Glycol; Propylene Glycols; Skin Absorption; Skin Diseases, Infectious; Thymidine; Trifluridine	1984
The incorporation of trifluorothymidine into calf thymus DNA in a cell-free system does not lead to chain termination. Molecular pharmacology, 1980, Volume: 18, Issue:1 Topics: Animals; Cattle; Cell-Free System; DNA; DNA-Directed DNA Polymerase; HeLa Cells; Humans; Hydrolysis; In Vitro Techniques; Peptide Chain Termination, Translational; Thymidine; Thymus Gland; Trifluridine	1980
[Clinical experience with different methods of treating herpes corneae (author's transl)]. Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 176, Issue:2 Topics: Debridement; Drug Therapy, Combination; Humans; Idoxuridine; Iodine; Keratitis, Dendritic; Thymidine; Trifluridine	1980
[Herpetic recurrence prophylaxis with trifluorothymidine after keratoplasty (author's transl)]. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1980, Volume: 180, Issue:1 Topics: Adolescent; Adult; Aged; Corneal Transplantation; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Recurrence; Thymidine; Trifluridine	1980
Trifluorothymidine resistance and colony size in L5178Y/TK +/- cells treated with methyl methanesulfonate. Journal of cellular physiology, 1981, Volume: 106, Issue:3 Topics: Animals; Cell Division; Cell Line; Cell Survival; Clone Cells; Drug Resistance; Genetic Variation; Karyotyping; Lymphoma; Methyl Methanesulfonate; Mice; Mutation; Thymidine; Thymidine Kinase; Trifluridine	1981
Allergic contact dermatitis to trifluorothymidine eyedrops. Contact dermatitis, 1981, Volume: 7, Issue:1 Topics: Cross Reactions; Dermatitis, Contact; Humans; Male; Middle Aged; Ophthalmic Solutions; Patch Tests; Thymidine; Trifluridine	1981
The utilization of trifluorothymidine (TFT) to select for thymidine kinase-deficient (TK-/-) mutants from L5178Y/TK+/- mouse lymphoma cells. Mutation research, 1981, Volume: 85, Issue:5 Topics: Animals; Bromodeoxyuridine; Cell Separation; Dose-Response Relationship, Drug; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Thymidine; Thymidine Kinase; Trifluridine	1981
Experimental stroma herpes simplex keratitis. Influence of treatment with topical bromovinyldeoxyuridine and trifluridine. Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:4 Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Corneal Diseases; Disease Models, Animal; Drug Administration Schedule; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Thymidine; Trifluridine	1982
[A patient with contact allergy for various virostatic agents used in herpetic keratitis]. Nederlands tijdschrift voor geneeskunde, 1982, Aug-07, Volume: 126, Issue:32 Topics: Antiviral Agents; Dermatitis, Contact; Humans; Idoxuridine; Keratitis, Dendritic; Male; Middle Aged; Skin Tests; Thymidine; Trifluridine	1982
Herpes zoster dendritic keratitis. Journal of the American Optometric Association, 1982, Volume: 53, Issue:10 Topics: Corneal Diseases; Herpes Zoster Ophthalmicus; Humans; Male; Middle Aged; Thymidine; Trifluridine	1982
In vitro sensitivity of macropodid herpesvirus 2 to selected anti-herpetic compounds. Journal of wildlife diseases, 1996, Volume: 32, Issue:1 Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxycytidine; Bromodeoxyuridine; Cell Line; Cytarabine; Deoxycytidine; Herpesviridae; Herpesviridae Infections; Idoxuridine; Macropodidae; Microbial Sensitivity Tests; Neutralization Tests; Thymidine; Trifluridine; Vidarabine	1996
Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2'-deoxyribonucleosides. Biochemical pharmacology, 2000, May-15, Volume: 59, Issue:10 Topics: Administration, Oral; Animals; Antineoplastic Agents; Dogs; Drug Synergism; Enzyme Inhibitors; Female; Humans; Idoxuridine; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Placenta; Pyrrolidines; Recombinant Proteins; Structure-Activity Relationship; Thymidine; Thymidine Phosphorylase; Trifluridine; Uracil	2000
Intracellular thymidylate synthase inhibition by trifluorothymidine in FM3A cells. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Phosphorylation; Thymidine; Thymidine Phosphorylase; Thymidylate Synthase; Time Factors; Trifluridine	2004
Potentiation of the antitumor activity of alpha, alpha, alpha-trifluorothymidine by the co-administration of an inhibitor of thymidine phosphorylase at a suitable molar ratio in vivo. International journal of oncology, 2005, Volume: 27, Issue:2 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Thymidine; Thymidine Phosphorylase; Time Factors; Trifluridine; Xenograft Model Antitumor Assays	2005
Involvement of concentrative nucleoside transporter 1 in intestinal absorption of trifluorothymidine, a novel antitumor nucleoside, in rats. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2 Topics: 2,4-Dinitrophenol; Animals; Antineoplastic Agents; Binding, Competitive; Drug Interactions; Female; Inosine; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Male; Membrane Transport Proteins; Oocytes; Perfusion; Rats; Rats, Sprague-Dawley; RNA; RNA, Complementary; Sodium Azide; Thymidine; Thymidine Phosphorylase; Thymidylate Synthase; Trifluridine; Uridine; Xenopus laevis	2012
Can the L5178Y Tk+/- mouse lymphoma assay detect epigenetic silencing? Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59 Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Clone Cells; DNA Methylation; Drug Resistance, Neoplasm; Epigenetic Repression; Evaluation Studies as Topic; Hypoxanthine; Leukemia L5178; Mice; Mutagenicity Tests; Mutagens; Mutation; Neoplasm Proteins; Thymidine; Thymidine Kinase; Trifluridine	2013