trifluridine has been researched along with regorafenib in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 26 (42.62) | 24.3611 |
| 2020's | 35 (57.38) | 2.80 |
| Authors | Studies |
|---|---|
| Goldberg, R | 1 |
| Akashi, K; Arita, S; Ariyama, H; Baba, E; Esaki, T; Hirano, G; Kusaba, H; Makiyama, A; Matsushita, Y; Mitsugi, K; Shibata, Y; Shimokawa, HK; Shirakawa, T; Tamura, S | 1 |
| Doki, Y; Haraguchi, N; Hata, T; Hayashi, T; Kudo, T; Mizushima, T; Mori, M; Nishimura, J; Sakai, D; Satoh, T; Sueda, T; Sugiura, T; Takahashi, H | 1 |
| Marshall, JL; Salem, ME; Weinberg, BA | 1 |
| Andrikou, K; Berardi, R; Bianconi, M; Bittoni, A; Cabras, F; Cascinu, S; Del Prete, M; Faloppi, L; Giampieri, R; Maccaroni, E; Pusceddu, V; Restivo, A; Scartozzi, M; Scintu, F; Zorcolo, L | 1 |
| Ando, M; Fukutomi, A; Hamauchi, S; Ishihara, M; Kadowaki, S; Kito, Y; Komori, A; Machida, N; Masuishi, T; Mori, K; Muro, K; Narita, Y; Onozawa, Y; Tajika, M; Tanaka, T; Taniguchi, H; Todaka, A; Tsushima, T; Ura, T; Yamazaki, K; Yasui, H; Yokota, T | 1 |
| Antonuzzo, L; Aprile, G; Baretti, M; Battaglin, F; Berenato, R; Beretta, G; Bozzarelli, S; Cinieri, S; Cremolini, C; de Braud, F; Falcone, A; Formica, V; Ghidini, M; Lonardi, S; Loupakis, F; Marmorino, F; Mennitto, A; Miceli, R; Morano, F; Mosconi, S; Petrelli, F; Pietrantonio, F; Rimassa, L; Rossini, D; Spada, D; Tamburini, E | 1 |
| Barzi, A; Berger, MD; Cao, S; Gopez, R; Lenz, HJ; Loupakis, F; Marmorino, F; Mennitto, A; Miyamoto, Y; Murgioni, S; Ning, Y; Okazaki, S; Rossini, D; Schirripa, M; Suenaga, M; Yamaguchi, T; Yang, D; Zhang, W | 1 |
| Arnold, D; Hofheinz, RD; Kubicka, S; Vogel, A | 1 |
| Baba, E; Denda, T; Enomoto, M; Esaki, T; Fukuoka, S; Gosho, M; Ishikawa, T; Kajiwara, T; Kashiwada, T; Komatsu, Y; Kumekawa, Y; Makiyama, C; Moriwaki, T; Okuyama, H; Sakai, D; Satake, H; Shimada, Y; Sugimoto, N; Sugiyama, M; Suto, T; Takashima, A; Tamura, T; Taniguchi, H; Watanabe, T; Yamashita, K; Yamazaki, K | 1 |
| Bullement, A; Fougeray, R; Hatswell, AJ; Underhill, S | 1 |
| Abrahao, ABK; Berry, S; Chan, KKW; Ko, YJ | 1 |
| Arnold, D; Moreno Vera, S; Mounedji, N; Prager, GW; Quintela, A; Stein, A; Taieb, J | 1 |
| Bonetti, A; Giuliani, J | 1 |
| Barghout, V; Duh, MS; Fuchs, CS; Patel, AK; Tabesh, M; Wynant, W; Xiao, Y; Yenikomshian, MA | 1 |
| Chu, E | 1 |
| Bianconi, D; Drimmel, M; Gleiss, A; Kieler, M; Prager, GW; Scheithauer, W; Siebenhüner, A; Unseld, M; Winder, T | 1 |
| Baba, E; Denda, T; Esaki, T; Fukuoka, S; Ishikawa, T; Ito, M; Kajiwara, T; Kashiwada, T; Katsumata, K; Kishimoto, J; Komatsu, Y; Kumekawa, Y; Makiyama, A; Moriwaki, T; Oki, E; Okuyama, H; Sakai, D; Satake, H; Shimada, Y; Sugimoto, N; Suto, T; Takashima, A; Tamura, T; Taniguchi, H; Tsuchihashi, K; Ueno, H; Yamashita, K; Yamazaki, K | 1 |
| Barzi, A; Cho, SK; Hay, JW | 1 |
| Nakamura, A; Oki, M; Shinamura, N; Sugaya, M; Sugaya, T; Takagi, K | 1 |
| Matsuo, K; Matsuoka, K; Nakagawa, F; Okabe, H; Takechi, T; Tanaka, N | 1 |
| Akiyama, T; Baba, H; Baba, Y; Eto, K; Hiyoshi, Y; Iwagami, S; Kiyozumi, Y; Miyamoto, Y; Yohei, N; Yoshida, N | 1 |
| Ahn, DH; Bekaii-Saab, T; Benkhadra, R; Firwana, B; Hubbard, JM; Mody, K; Murad, MH; Sonbol, MB; Walden, DJ; Wang, Z | 1 |
| Barghout, V; Duh, MS; Germain, G; Jacques, P; Laliberté, F; Patel, AK; Yenikomshian, MA | 1 |
| Bekaii-Saab, T; Grothey, A; Marshall, JL | 1 |
| Chen, J; Lin, H; Peng, Y; Wang, J | 1 |
| Denda, T; Enomoto, M; Esaki, T; Fukuoka, S; Hatachi, Y; Ishikawa, T; Kajiwara, T; Kashiwada, T; Komatsu, Y; Kumekawa, Y; Makiyama, A; Masuishi, T; Moriwaki, T; Oki, E; Sakai, D; Shimada, Y; Sugimoto, N; Suto, T; Takashima, A; Tamura, T; Tsuchihashi, K; Tsuji, A; Ueno, H; Yamashita, K; Yamazaki, K | 1 |
| Li, J; Peng, Z; Shen, L; Wang, Q; Wang, X; Zhang, Q | 1 |
| Cao, M; Zhang, J; Zhou, M | 1 |
| Borner, M; De Dosso, S; Meisel, A; Siebenhüner, A; Wagner, AD | 1 |
| Andrikou, K; Casadei-Gardini, A; Cascinu, S; Gelsomino, F; Orsi, G; Rovesti, G; Scartozzi, M; Spallanzani, A; Tamburini, E; Ulivi, P; Vagheggini, A | 1 |
| Kadowaki, S; Kawakami, T; Kawamoto, Y; Komatsu, Y; Masuishi, T; Muranaka, T; Muro, K; Nakatsumi, H; Omae, K; Onozawa, Y; Tajika, M; Taniguchi, H; Yamazaki, K; Yasui, H; Yuki, S | 1 |
| Hatachi, Y; Kato, T; Kotaka, M; Ogata, M; Ogata, T; Satake, H; Tsuji, A; Yasui, H | 1 |
| Kashiwa, M; Matsushita, R | 1 |
| Liu, H; Su, GL; Wang, JC; Wang, YY | 1 |
| Colaone, F; Hawkins, NS; Pollock, RF; Ross, PJ; Shergill, S; Walter, T | 1 |
| Antonuzzo, L; Castiglione, F; Di Costanzo, F; Lastraioli, E; Lavacchi, D; Messerini, L; Palmieri, VE | 1 |
| Kawakami, K; Nakashima, M; Takeuchi, M | 1 |
| Bonetti, A; Giuliani, J; Insolda, J; Pigozzi, E | 1 |
| Kawakami, K; Nakashima, M; Takeuchi, M; Tanaka, S | 1 |
| Azzurro, M; Bonetti, A; Fiorica, F; Giuliani, J; Ponturo, G; Ruzzenente, A | 1 |
| Denda, T; Esaki, T; Fukuoka, S; Hatachi, Y; Kajiwara, T; Kumekawa, Y; Makiyama, A; Masuishi, T; Moriwaki, T; Niisato, Y; Shimada, Y; Sugimoto, N; Suto, T; Takashima, A; Yamazaki, K | 1 |
| Ciardiello, F; Grothey, A; Marshall, JL | 1 |
| Marshall, JL | 1 |
| Bekaii-Saab, TS; Loupakis, F; Marshall, JL | 1 |
| Bekaii-Saab, TS; Grothey, A; Prager, GW; Yoshino, T | 1 |
| Ceribelli, A; Chilelli, MG; DE Marco, S; Gemma, D; Grande, R; Morandi, MG; Ruggeri, EM; Saltarelli, R; Signorelli, C; Sperduti, I; Spinelli, GP; Zoratto, F | 1 |
| Cervantes, A; Ciardiello, D; Ciardiello, F; De Falco, V; Famiglietti, V; Fenocchio, E; Lombardi, P; Martinelli, E; Martini, G; Milanesio, M; Napolitano, S; Rosellò, S; Troiani, T; Vitale, P; Zanaletti, N | 1 |
| Abhyankar, R; Barghout, VE; Brais, LK; Duh, MS; Fuchs, CS; Huynh, L; Ng, K; Patel, AK; Yenikomshian, MA | 1 |
| Antista, M; Antoniotti, C; Boccaccino, A; Borelli, B; Bosco, MF; Carullo, M; Conca, V; Cosentino, P; Cremolini, C; Germani, MM; Giordano, M; Marmorino, F; Martini, S; Masi, G; Moretto, R; Pietrantonio, F; Prisciandaro, M; Rossini, D; Vetere, G; Zaffaroni, N; Zucchelli, G; Zuco, V | 1 |
| Artru, P; Bouché, O; Coriat, R; Coutzac, C; De La Fouchardière, C; Doat, S; Gallois, C; Henriques, J; Masson, T; Moulin, V; Saint, A; Taieb, J; Tougeron, D; Trouilloud, I; Vernerey, D | 1 |
| Boku, N; Hirano, H; Iwasa, S; Okita, N; Oshima, K; Shoji, H; Takashima, A | 1 |
| Babajanyan, S; Barzi, A; Bekaii-Saab, T; Cho, SK; Hocum, B; Kavati, A | 1 |
| de Castro, NM; García-Beloso, N; Gayoso-Rey, M; López-López, A; Piñeiro-Corrales, G; Robles-Torres, D; Romero-Ventosa, EY | 1 |
| Antista, M; Antoniotti, C; Boccaccino, A; Borelli, B; Conca, V; Cremolini, C; Crucitta, S; Cucchiara, F; Danesi, R; Del Re, M; Germani, MM; Leone, AG; Marmorino, F; Masi, G; Moretto, R; Pietrantonio, F; Provenzano, L; Rossini, D; Spagnoletti, A | 1 |
| Ikoma, T; Matsumoto, T; Miura, K; Nagai, H; Takatani, M; Tsuduki, T; Watanabe, T; Yamamura, S; Yasui, H | 1 |
| Florou, V; Garrido-Laguna, I; Haaland, B; Nevala-Plagemann, C; Sama, S; Shen, J; Ying, J | 1 |
| Araujo, KB; Festa, J; Mardegan, L; Meton, F; Piranda, DN; Victorino, APOS | 1 |
| Arnold, D; Bassam, A; Chong, G; Cremolini, C; Csőszi, T; Cubillo Gracian, A; Dasari, A; Ducreux, M; Elez, E; Elme, A; Eng, C; Faugeras, L; García-Alfonso, P; Garcia-Carbonero, R; Ghiringhelli, F; Hochster, HS; Jones, J; Kania, M; Kasper, S; Kocsis, J; Krauss, J; Lonardi, S; Masuishi, T; Nanda, S; Paulson, AS; Randrian, V; Sartore-Bianchi, A; Satoh, T; Schelman, WR; Shergill, A; Sobrero, A; Tabernero, J; Tomasek, J; Van Cutsem, E; Yang, Z; Yao, J; Yoshino, T | 1 |
| Kagawa, Y; Kunitomi, Y; Nakashima, M; Okude, R; Shinozaki, E; Tone, T | 1 |
14 review(s) available for trifluridine and regorafenib
| Article | Year |
|---|---|
Trifluridine/tipiracil and regorafenib: new weapons in the war against metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Humans; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Treatment Outcome; Trifluridine | 2016 |
Treatment decisions in metastatic colorectal cancer - Beyond first and second line combination therapies.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Phenylurea Compounds; Prognosis; Pyridines; Risk Assessment; Survival Analysis; Treatment Outcome; Trifluridine | 2017 |
A Comparison of Regorafenib and TAS-102 for Metastatic Colorectal Cancer: A Systematic Review and Network Meta-analysis.
Topics: Antineoplastic Agents; Colorectal Neoplasms; Drug Combinations; Humans; Network Meta-Analysis; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Treatment Outcome; Trifluridine; Uracil | 2018 |
Beyond second-line therapy in patients with metastatic colorectal cancer: a systematic review.
Topics: Colorectal Neoplasms; Disease Progression; Drug Combinations; Drugs, Investigational; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine; Uracil | 2018 |
A Systematic Review and Network Meta-Analysis of Regorafenib and TAS-102 in Refractory Metastatic Colorectal Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Humans; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Pyrrolidines; Randomized Controlled Trials as Topic; Survival Rate; Thymine; Treatment Outcome; Trifluridine; Uracil | 2019 |
Comparison of Regorafenib, Fruquintinib, and TAS-102 in Previously Treated Patients with Metastatic Colorectal Cancer: A Systematic Review and Network Meta-Analysis of Five Clinical Trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzofurans; Colonic Neoplasms; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Humans; Network Meta-Analysis; Phenylurea Compounds; Pyridines; Pyrrolidines; Quinazolines; Rectal Neoplasms; Thymine; Trifluridine; Uracil | 2019 |
Regorafenib, TAS-102, or fruquintinib for metastatic colorectal cancer: any difference in randomized trials?
Topics: Antineoplastic Agents; Benzofurans; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Disease Progression; Drug Combinations; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Network Meta-Analysis; Phenylurea Compounds; Progression-Free Survival; Pyridines; Pyrrolidines; Quinazolines; Randomized Controlled Trials as Topic; Thymine; Time Factors; Trifluridine; Uracil | 2020 |
Comparison of efficacy and safety for patients with beyond second line treated metastatic colorectal cancer: a network meta-analysis of randomized controlled trials.
Topics: Antineoplastic Agents, Immunological; Cetuximab; Colorectal Neoplasms; Drug Combinations; Humans; Network Meta-Analysis; Panitumumab; Phenylurea Compounds; Proto-Oncogene Proteins p21(ras); Pyridines; Pyrrolidines; Randomized Controlled Trials as Topic; Survival Analysis; Thymine; Trifluridine | 2020 |
Metastatic Colorectal Carcinoma after Second Progression and the Role of Trifluridine-Tipiracil (TAS-102) in Switzerland.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Disease Progression; Drug Combinations; Humans; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Pyrrolidines; Survival Rate; Switzerland; Thymine; Treatment Outcome; Trifluridine; Uracil | 2020 |
A meta-analysis comparing regorafenib with TAS-102 for treating refractory metastatic colorectal cancer.
Topics: Colorectal Neoplasms; Drug Combinations; Humans; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2020 |
Systematic review and network meta-analyses of third-line treatments for metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Colorectal Neoplasms; Double-Blind Method; Drug Combinations; Humans; Microspheres; Neoplasm Metastasis; Network Meta-Analysis; Palliative Care; Phenylurea Compounds; Progression-Free Survival; Pyridines; Pyrrolidines; Randomized Controlled Trials as Topic; Thymine; Trifluridine; Uracil; Yttrium Radioisotopes | 2020 |
Dose-escalation strategy in refractory metastatic colorectal cancer: A change in terms of cost-effectiveness.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Combinations; Drug Costs; Humans; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2021 |
Trifluridine/tipiracil (FTD/TPI) and regorafenib in older patients with metastatic colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Frontotemporal Dementia; Humans; Rectal Neoplasms; Trifluridine; Uracil | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
5 trial(s) available for trifluridine and regorafenib
| Article | Year |
|---|---|
Estimating 12-week death probability in patients with refractory metastatic colorectal cancer: the Colon Life nomogram.
Topics: Aged; Colon; Colorectal Neoplasms; Cost-Benefit Analysis; Disease-Free Survival; Drug Combinations; Female; Humans; Logistic Models; Male; Middle Aged; Neoplasm Metastasis; Nomograms; Phenylurea Compounds; Prognosis; Proportional Hazards Models; Pyridines; Pyrrolidines; Thymine; Trifluridine; Uracil | 2017 |
Cost-effectiveness Analysis of Regorafenib and TAS-102 in Refractory Metastatic Colorectal Cancer in the United States.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Cost-Benefit Analysis; Double-Blind Method; Drug Combinations; Drug Resistance, Neoplasm; Follow-Up Studies; Humans; Liver Neoplasms; Markov Chains; Palliative Care; Phenylurea Compounds; Prognosis; Pyridines; Pyrrolidines; Quality-Adjusted Life Years; Salvage Therapy; Survival Rate; Thymine; Trifluridine; United States; Uracil | 2018 |
Comparative Cost-utility Analysis of Regorafenib and Trifluridine/Tipiracil in The Treatment of Metastatic Colorectal Cancer in Japan.
Topics: Adult; Colorectal Neoplasms; Cost-Benefit Analysis; Drug Combinations; Humans; Japan; Phenylurea Compounds; Pyridines; Pyrrolidines; Quality-Adjusted Life Years; Thymine; Trifluridine | 2020 |
Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Double-Blind Method; Humans; Quality of Life; Rectal Neoplasms; Trifluridine; Vascular Endothelial Growth Factor A | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
43 other study(ies) available for trifluridine and regorafenib
| Article | Year |
|---|---|
Emerging phase 3 data in relapsed/refractory metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Humans; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Phenylurea Compounds; Pyridines; Pyrrolidines; Retreatment; Thymine; Treatment Outcome; Trifluridine; Uracil | 2016 |
Efficacy and Safety of TAS-102 in Clinical Practice of Salvage Chemotherapy for Metastatic Colorectal Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Male; Middle Aged; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; Salvage Therapy; Survival Analysis; Thymine; Treatment Outcome; Trifluridine; Uracil | 2016 |
Efficacy and Safety of Regorafenib or TAS-102 in Patients with Metastatic Colorectal Cancer Refractory to Standard Therapies.
Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Pyrrolidines; Randomized Controlled Trials as Topic; Thymine; Treatment Outcome; Trifluridine; Uracil | 2016 |
The Role of Aspirin as Antitumoral Agent for Heavily Pretreated Patients With Metastatic Colorectal Cancer Receiving Capecitabine Monotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Capecitabine; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine; Uracil | 2017 |
Regorafenib Versus Trifluridine/Tipiracil for Refractory Metastatic Colorectal Cancer: A Retrospective Comparison.
Topics: Aged; Antineoplastic Agents; Cohort Studies; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Japan; Male; Middle Aged; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Survival Rate; Thymine; Treatment Outcome; Trifluridine; Uracil | 2017 |
Genetic variants of DNA repair-related genes predict efficacy of TAS-102 in patients with refractory metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Disease-Free Survival; DNA Repair Enzymes; Drug Combinations; Drug Resistance, Neoplasm; Female; Genetic Association Studies; Humans; Liver Neoplasms; Male; Middle Aged; Phenylurea Compounds; Proportional Hazards Models; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Treatment Outcome; Trifluridine; Uracil | 2017 |
Propensity Score Analysis of Regorafenib Versus Trifluridine/Tipiracil in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapy (REGOTAS): A Japanese Society for Cancer of the Colon and Rectum Multicenter Observational Study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Japan; Liver Neoplasms; Male; Middle Aged; Phenylurea Compounds; Prognosis; Propensity Score; Pyridines; Pyrrolidines; Retrospective Studies; Salvage Therapy; Survival Rate; Thymine; Trifluridine; Uracil | 2018 |
Cost-effectiveness of Trifluridine/tipiracil for Previously Treated Metastatic Colorectal Cancer in England and Wales.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Cost-Benefit Analysis; Drug Combinations; England; Female; Humans; Male; Middle Aged; Phenylurea Compounds; Pyridines; Pyrrolidines; Randomized Controlled Trials as Topic; Salvage Therapy; Thymine; Trifluridine; Uracil; Wales | 2018 |
Regorafenib or Trifluridine/Tipiracil in Refractory Metastatic Colorectal Cancer? A Perspective on the Basis of Pharmacological Costs.
Topics: Colorectal Neoplasms; Humans; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Trifluridine | 2018 |
Real-world Treatment Patterns Among Patients With Colorectal Cancer Treated With Trifluridine/Tipiracil and Regorafenib.
Topics: Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Disease Progression; Drug Combinations; Drug Resistance, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Treatment Outcome; Trifluridine; United States; Uracil | 2018 |
How I treat chemorefractory metastatic colorectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; Lymphatic Metastasis; Neoplasm Staging; Nivolumab; Phenylurea Compounds; Prognosis; Proto-Oncogene Proteins B-raf; Pyridines; Pyrrolidines; Quinazolines; Randomized Controlled Trials as Topic; Survival Analysis; Thymine; Trastuzumab; Trifluridine; Uracil; Vascular Endothelial Growth Factor Receptor-1 | 2018 |
Optimizing Treatment Sequence for Late-line Metastatic Colorectal Cancer Patients Using Trifluridine/Tipiracil and Regorafenib.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Phenylurea Compounds; Prognosis; Pyridines; Pyrrolidines; Retrospective Studies; Survival Rate; Thymine; Trifluridine; Uracil | 2018 |
Role of Predictive Value of the Modified Glasgow Prognostic Score for Later-line Chemotherapy in Patients With Metastatic Colorectal Cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C-Reactive Protein; Colorectal Neoplasms; Drug Combinations; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Nutritional Status; Phenylurea Compounds; Prognosis; Pyridines; Pyrrolidines; Retrospective Studies; Serum Albumin, Human; Survival Rate; Thymine; Trifluridine; Uracil | 2018 |
[Regorafenib and Trifluridine and Tipiracil Hydrochloride Can Potentially Improve the Survival Time for Patients with Advanced or Recurrent Colorectal Cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Phenylurea Compounds; Pyridines; Recurrence; Treatment Outcome; Trifluridine; Young Adult | 2018 |
Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Humans; Male; Mice, Nude; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2018 |
Low Skeletal Muscle Mass before Salvage-Line Chemotherapy Is a Poor Prognostic Factor in Patients with Refractory Metastatic Colorectal Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Muscle, Skeletal; Phenylurea Compounds; Prognosis; Proportional Hazards Models; Pyridines; Pyrrolidines; Retrospective Studies; Salvage Therapy; Thymine; Treatment Outcome; Trifluridine; Uracil | 2019 |
Real-World Adherence in Patients with Metastatic Colorectal Cancer Treated with Trifluridine plus Tipiracil or Regorafenib.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Colorectal Neoplasms; Drug Combinations; Female; Humans; Longitudinal Studies; Male; Medication Adherence; Middle Aged; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Trifluridine | 2020 |
Sequencing beyond the second-line setting in metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Humans; Neoplasm Metastasis; Phenylurea Compounds; Prognosis; Pyridines; Pyrrolidines; Salvage Therapy; Survival Rate; Thymine; Trifluridine; Uracil | 2019 |
Prognostic scores for evaluating the survival benefit of regorafenib or trifluridine/tipiracil in patients with metastatic colorectal cancer: an exploratory analysis of the REGOTAS study.
Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; Drug Combinations; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Treatment Outcome; Trifluridine; Uracil | 2020 |
Is There an Optimal Choice in Refractory Colorectal Cancer? A Network Meta-Analysis.
Topics: Antineoplastic Agents; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Humans; Network Meta-Analysis; Panitumumab; Phenylurea Compounds; Progression-Free Survival; Prospective Studies; Pyridines; Pyrrolidines; Randomized Controlled Trials as Topic; Thymine; Trifluridine | 2020 |
Impact of tumour growth rate during preceding treatment on tumour response to regorafenib or trifluridine/tipiracil in refractory metastatic colorectal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Decision-Making; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Female; Humans; Male; Middle Aged; Phenylurea Compounds; Progression-Free Survival; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Time Factors; Trifluridine; Tumor Burden; Uracil | 2019 |
Regorafenib vs trifluridine/tipiracil for metastatic colorectal cancer refractory to standard chemotherapies: A multicenter retrospective comparison study in Japan.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Female; Humans; Japan; Male; Middle Aged; Phenylurea Compounds; Progression-Free Survival; Pyridines; Pyrrolidines; Retrospective Studies; Salvage Therapy; Thymine; Treatment Outcome; Trifluridine; Uracil | 2020 |
Evaluation of RAS mutational status through BEAMing assay to monitor disease progression of metastatic colorectal cancer: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Disease Progression; DNA Mutational Analysis; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liquid Biopsy; Male; Middle Aged; Mutation; Phenylurea Compounds; Pyridines; Pyrrolidines; ras Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine; Trifluridine | 2020 |
Effectiveness and Safety of Regorafenib vs. Trifluridine/Tipiracil in Unresectable Colorectal Cancer: A Retrospective Cohort Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Female; Humans; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Salvage Therapy; Survival Analysis; Thymine; Treatment Outcome; Trifluridine | 2020 |
Trifluridine/tipiracil or regorafenib in refractory metastatic colorectal cancer: from clinical trials to daily clinical practice.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Humans; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2020 |
Salvage Therapy After Regorafenib or Trifluridine/Tipiracil Treatment of Metastatic Colorectal Cancer: A Conditional Landmark Analysis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Salvage Therapy; Survival Analysis; Thymine; Treatment Outcome; Trifluridine | 2021 |
Clinical Outcomes Following Trifluridine/Tipiracil Treatment for Patients With Metastatic Colorectal Cancer Ineligible for Regorafenib Treatment.
Topics: Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; Comorbidity; Drug Combinations; Female; Humans; Japan; Male; Middle Aged; Neoplasm Metastasis; Patient Selection; Phenylurea Compounds; Progression-Free Survival; Pyridines; Pyrrolidines; Retrospective Studies; Salvage Therapy; Survival Analysis; Thymine; Treatment Outcome; Trifluridine | 2021 |
How to incorporate a chemo-free interval into the management of metastatic colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; COVID-19; Disease Management; Drug Combinations; Humans; Neoplasm Metastasis; Phenylurea Compounds; Pyridines; Pyrrolidines; Quality of Life; Thymine; Time Factors; Trifluridine | 2020 |
Third-line treatments for the management of metastatic colorectal cancer: why to change the mechanism of action after frontline chemotherapy, and insights into management during the COVID-19 pandemic.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Colorectal Neoplasms; COVID-19; Disease Management; Drug Combinations; ErbB Receptors; Humans; Neoplasm Metastasis; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2020 |
Transitioning from second-line to third-line therapy in metastatic colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Decision-Making; Colorectal Neoplasms; Disease Management; Drug Combinations; Humans; Neoplasm Metastasis; Palliative Care; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2021 |
Optimizing the treatment sequence from second-line to third-line therapy in patients with metastatic colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease Management; Disease Progression; Drug Combinations; Humans; Neoplasm Metastasis; Phenylurea Compounds; Progression-Free Survival; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2020 |
Regorafenib-to-trifluridine/tipiracil Versus the Reverse Sequence for Refractory Metastatic Colorectal Cancer Patients: A Multicenter Retrospective Real-life Experience.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Phenylurea Compounds; Progression-Free Survival; Pyridines; Pyrrolidines; Thymine; Trifluridine | 2021 |
Retrospective Study of Regorafenib Versus TAS-102 Efficacy and Safety in Chemorefractory Metastatic Colorectal Cancer (mCRC) Patients: A Multi-institution Real Life Clinical Data.
Topics: Colorectal Neoplasms; Drug Combinations; Humans; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Trifluridine; Uracil | 2021 |
Trifluridine/Tipiracil and Regorafenib in Patients with Metastatic Colorectal Cancer: A Retrospective Study at a Tertiary Oncology Center.
Topics: Colorectal Neoplasms; Humans; Longitudinal Studies; Phenylurea Compounds; Pyridines; Pyrrolidines; Retrospective Studies; Thymine; Trifluridine | 2021 |
Early modulation of Angiopoietin-2 plasma levels predicts benefit from regorafenib in patients with metastatic colorectal cancer.
Topics: Angiopoietin-2; Colonic Neoplasms; Colorectal Neoplasms; Drug Combinations; Frontotemporal Dementia; Humans; Phenylurea Compounds; Pyridines; Rectal Neoplasms; Retrospective Studies; Trifluridine | 2022 |
Sequential Treatment With Trifluridine/Tipiracil and Regorafenib in Refractory Metastatic Colorectal Cancer Patients: An AGEO Prospective "Real-World Study".
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Drug Combinations; Frontotemporal Dementia; Humans; Phenylurea Compounds; Prospective Studies; Pyridines; Pyrrolidines; Rectal Neoplasms; Thymine; Trifluridine; Uracil | 2022 |
Influence of precedent drug on the subsequent therapy in the sequence of trifluridine/tipiracil with/out bevacizumab and regorafenib for unresectable or recurrent colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Humans; Neoplasm Recurrence, Local; Phenylurea Compounds; Pyridines; Pyrrolidines; Thymine; Trifluridine; Uracil | 2022 |
Value-Based Analysis of Therapies in Refractory Metastatic Colorectal Cancer in US.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Cost-Benefit Analysis; Humans; Phenylurea Compounds; Pyridines; Quality-Adjusted Life Years; Rectal Neoplasms; Trifluridine | 2022 |
Regorafenib and trifluridine/tipiracil in real clinical practice.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Humans; Male; Phenylurea Compounds; Retrospective Studies; Trifluridine; Uracil | 2022 |
TK-1, TP, Ang-2, and Tie-2 mRNA expression in plasma-derived microvesicles of chemo-refractory metastatic colorectal cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Colonic Neoplasms; Colorectal Neoplasms; Drug Combinations; Humans; Rectal Neoplasms; Trifluridine; Uracil | 2023 |
Regorafenib is suitable for advanced colorectal cancer patients who have previously received trifluridine/tipiracil plus bevacizumab.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Drug Combinations; Female; Humans; Male; Middle Aged; Phenylurea Compounds; Pyrrolidines; Retrospective Studies; Thymine; Trifluridine; Uracil | 2023 |
A Real-World Comparison of Regorafenib and Trifluridine/Tipiracil in Refractory Metastatic Colorectal Cancer in the United States.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Drug Combinations; Humans; Phenylurea Compounds; Prospective Studies; Rectal Neoplasms; Trifluridine; United States; Uracil | 2023 |
Real-world evidence of trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer using an administrative claims database in Japan.
Topics: Bevacizumab; Colonic Neoplasms; Colorectal Neoplasms; Frontotemporal Dementia; Humans; Japan; Retrospective Studies; Trifluridine; Uracil | 2023 |