Page last updated: 2024-08-17

trifluridine and acyclovir

trifluridine has been researched along with acyclovir in 106 studies

Research

Studies (106)

Timeframe	Studies, this research(%)	All Research%
pre-1990	55 (51.89)	18.7374
1990's	22 (20.75)	18.2507
2000's	19 (17.92)	29.6817
2010's	7 (6.60)	24.3611
2020's	3 (2.83)	2.80

Authors

Authors	Studies
Cha, SH; Endou, H; Kanai, Y; Kimura, M; Sekine, T; Tsuda, M; Wada, S	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE	1
Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Birch, CJ; Doherty, R; Hayes, K; Lucas, CR; Mijch, A; Tachedjian, G; Tyssen, DP	1
Eglin, RP; Monteiro, E; Morley, A; Murphy, M	1
Arbesfeld, DM; Thomas, I	1
Helmy, MF; Hill, JM; Jemison, M; Kaufman, HE; Upadhyay, JM	1
Margolis, TP; Ostler, HB	1
Sundmacher, R	1
Kaufman, HE	4
Chen, CW	1
Davidson, MG; De Clercq, E; Guy, JS; Nasisse, MP; Sussman, W	1
Høvding, G	1
Bodor, N; Loftsson, T; Somogyi, G	1
Ayisi, NK; Babiuk, LA; Gupta, SV	1
Whitley, RJ	1
Bauer, DJ	1
Lee, JJ; Lin, TS; Mancini, WR; Otto, MJ; Prusoff, WH; Zucker, M	1
Araullo-Cruz, T; Capone, A; Gordon, A; Gordon, YJ; Romanowski, E; Sheppard, J	1
Bentele, B; Betz, JL; Mitchell, DH; Pizer, LI	1
Freeman, DJ; Spruance, SL	1
Behrens-Baumann, W; Quentin, CD; Vogel, M	1
Mimura, Y; Naito, T; Shiota, H	1
Eggleston, M	1
Fiscella, R; Peyman, GA; Small, GH; Smith, RT; Srinivasan, A	1
Maudgal, PC; Missotten, L; Molemans, M; Vrijghem, JC	1
Coquin, Y	1
Centifanto-Fitzgerald, YM; Kaufman, HE; Sanitato, JG; Varnell, ED	1
King, DH	1
Nicholson, KG	2
Kelley, E; Spector, SA; Tyndall, M	2
Annel, M; de Miranda, P; Kingham, JD; Poirier, RH	1
Cantell, K; de Koning, EW; van Bijsterveld, OP	1
Falcon, MG	1
Burkhardt, U; Wigand, R	1
Douglas, RG	1
Rytel, MW; Turner, PA	1
Darby, G; Field, H; McMillan, A	1
Nesburn, AB; Trousdale, MD	1
O'Brien, WJ; Taylor, JL	1
Nahmias, AJ; Schinazi, RF	1
Cheung, KS; Lang, DJ	1
Biron, KK; Elion, GB	1
Lefrock, JL; Smith, BR	1
Grieco, MH	1
Goudsmit, J; van der Noordaa, J	1
Huraux, JM; Ingrand, D	1
Denis, J; Hoang-Xuan, T; Pouliquen, Y; Renard, G	1
Patey, A; Petroutsos, G; Pouliquen, Y	1
Colin, J	2
Denis, J; Frot, P; Hoang-Xuan, T; Pouliquen, Y	1
Johansson, NG; Oberg, B	1
Craandijk, A; la Lau, C; Lamers, WR; Mierlobensteyn, T; Oosterhuis, JA; Renardel de Lavalette, JG; van Rij, G; Versteeg, J	2
Denis, J; Desbordes, JM; Giraud, J; Pouliquen, Y; Thompson, P	1
Craandijk, A; la Lau, C; Lamers, WP; Oosterhuis, JA; Renardel de Lavalette, JG; van Rij, G; Versteeg, J	1
Taylor, RF	1
Berger, TG; Rossi, S; Whitfeld, M	1
Barron, BA; Dawson, CR; Gee, L; Hauck, WW; Hyndiuk, RA; Jones, DB; Kaufman, HE; Kurinij, N; Sugar, J; Wilhelmus, KR	1
Balfour, HH; Benson, C; Braun, J; Cassens, B; Erice, A; Friedman-Kien, A; Klein, T; Polsky, B; Safrin, S	1
Abghari, SZ; Kaufman, HE; Schinazi, RF; Stulting, RD; Zhu, Z	1
Das, GK; Khokhar, S; Panda, A; Rao, V	1
Smith, G	1
Bailey, TC; Benson, CA; Cheeseman, SH; Farthing, C; Feinberg, J; Hurwitz, S; Kessler, HA; Korvick, JA; Kuritzkes, DR; McKinley, GF; Nevin, T; Owens, S; Safrin, S; Steigbigel, RT; Wettlaufer, B	1
Amin, AR; Luque, AE; Robinson, MR; Smith, DD; Swenson, CF	1
Asbell, PA; Bacchetti, P; Barron, BA; Dawson, CR; Gee, L; Hyndiuk, RA; Jones, DB; Kaufman, HE; Laibson, PR; Stulting, RD; Sugar, J; Wilhelmus, KR	1
Anastas, C; Dayan, M; McGhee, C	1
Kaufman, HE; Thompson, HW; Varnell, ED	1
Bartels, SP; Gordon, YJ; Romanowski, EG	1
Laibson, PR; Sudesh, S	1
Chilukuri, S; Rosen, T	1
Anand, BS; Bhattacharjee, PS; Dey, S; Hill, JM; Maruyama, K; Mitra, AK; Myles, ME; Nashed, YE	1
Cohen, EJ; Laibson, PR; Raber, IM; Rapuano, CJ; Rezende, RA; Uchoa, UB	1
Al-Muammar, A; Jackson, WB	1
Labetoulle, M	1
Macarie, S; Malachi, A; Pop, R	1
Chong, EM; Coats, DK; Jones, DB; Matoba, AY; Paysse, EA; Wilhelmus, KR	1
Berry, GK; Bower, KS; Dudenhoefer, EJ; Fillmore, GL; Grabenstein, JD; Madigan, WP; Ward, TP	1
Ramaesh, K; Roberts, F; Sandinha, T; Zaher, SS	1
Brummitt, CF	1
Goh, CL; Tan, HH	1
Lonsberry, BB	1
Kamel, A; Munson, B	1
Asbell, PA; Barron, BA; Dawson, CR; Hyndiuk, RA; Jones, DB; Kaufman, HE; Laibson, PR; Mitchell, BM; Stulting, RD; Sugar, J; Wilhelmus, KR	1
Dei, R; Gicquel, JJ; Menchini, U; Mencucci, R; Paladini, I	1
Bruno, M; Gerstenblith, AT; Ierardi, J; Levin, AV; Rotschild, T; Schnall, BM; Wang, E	1
Colby, KA; Liu, S; Pavan-Langston, D	1
Carter, SB; Cohen, EJ	1
Hammersmith, KM; Roozbahani, M	1
Maurya, AK; Maurya, SK; Mishra, N; Siddique, HR	1
Borase, H; Kapoor, D; Patil, C; Sharma, P; Shukla, D; Volety, I; Yadavalli, T	1

Reviews

19 review(s) available for trifluridine and acyclovir

Article	Year
Cutaneous herpes simplex virus infections. American family physician, 1991, Volume: 43, Issue:5 Topics: Acyclovir; Administration, Oral; Antiviral Agents; Diagnosis, Differential; Drug Resistance, Microbial; Foscarnet; Herpes Simplex; Humans; Idoxuridine; Infusions, Intravenous; Phosphonoacetic Acid; Recurrence; Skin Diseases, Infectious; Trifluridine; Vidarabine	1991
[Adverse side effects caused by topically applied antiviral agents in herpetic keratitis]. Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences, 1989, Volume: 5, Issue:8 Topics: Acyclovir; Administration, Topical; Antiviral Agents; Humans; Idoxuridine; Interferons; Keratitis, Dendritic; Trifluridine; Vidarabine	1989
Therapy for human herpesvirus infections. A perspective. The Alabama journal of medical sciences, 1985, Volume: 22, Issue:2 Topics: Acyclovir; Adult; Antiviral Agents; Chickenpox; Clinical Trials as Topic; Encephalitis; Herpes Simplex; Herpes Zoster; Herpesviridae Infections; Humans; Idoxuridine; Infant, Newborn; Infant, Newborn, Diseases; Keratitis, Dendritic; Trifluridine; Vidarabine	1985
A history of the discovery and clinical application of antiviral drugs. British medical bulletin, 1985, Volume: 41, Issue:4 Topics: Acyclovir; Animals; Antiviral Agents; Cricetinae; Cytarabine; Drug Industry; Guinea Pigs; Herpesviridae Infections; History, 20th Century; Humans; Influenza, Human; Macaca mulatta; Methisazone; Mice; Rabbits; Smallpox; Thiosemicarbazones; Trifluridine; Vaccinia virus; Vidarabine	1985
Basic biochemical and pharmacological aspects of antiviral agents. Antiviral research, 1985, Volume: Suppl 1 Topics: Acyclovir; Amantadine; Antiviral Agents; Bone Marrow Transplantation; Chemical Phenomena; Chemistry; Clinical Trials as Topic; DNA, Viral; Herpesviridae; Herpesviridae Infections; Humans; Idoxuridine; Influenza A virus; Influenza, Human; Keratitis, Dendritic; RNA, Viral; S-Adenosylhomocysteine; Thymidine Kinase; Trifluridine; Vidarabine; Viral Proteins; Virus Diseases	1985
Therapy of ocular herpes simplex infections. Infection control : IC, 1987, Volume: 8, Issue:7 Topics: Acyclovir; Antiviral Agents; Chemical Phenomena; Chemistry; Humans; Idoxuridine; Keratitis, Dendritic; Recurrence; Trifluridine; Vidarabine	1987
Advances in antiviral chemotherapy. Journal of the American Veterinary Medical Association, 1984, Nov-15, Volume: 185, Issue:10 Topics: Acyclovir; Adult; Animals; Antiviral Agents; Herpesviridae Infections; Humans; Idoxuridine; Infant, Newborn; Recurrence; Trifluridine; Vidarabine; Virus Diseases	1984
Antiviral therapy. Respiratory infections, genital herpes, and herpetic keratitis. Lancet (London, England), 1984, Sep-15, Volume: 2, Issue:8403 Topics: Acyclovir; Adult; Amantadine; Antiviral Agents; Child; Female; Herpes Genitalis; Humans; Idoxuridine; Infant; Infant, Newborn; Influenza, Human; Keratitis, Dendritic; Male; Picornaviridae Infections; Recurrence; Respiratory Syncytial Viruses; Respiratory Tract Infections; Respirovirus Infections; Rhinovirus; Ribavirin; Rimantadine; Trifluridine; Vidarabine	1984
Antiviral drugs 1983. The Medical clinics of North America, 1983, Volume: 67, Issue:5 Topics: Acyclovir; Amantadine; Antiviral Agents; Clinical Trials as Topic; Female; Herpes Genitalis; Herpes Simplex; Humans; Idoxuridine; Influenza, Human; Interferons; Keratitis, Dendritic; Male; Ribavirin; Rimantadine; Trifluridine; Vidarabine	1983
Diagnosis and management of viral infections. Comprehensive therapy, 1984, Volume: 10, Issue:6 Topics: Acyclovir; Amantadine; Antiviral Agents; Humans; Idoxuridine; Interferons; Serologic Tests; Time Factors; Trifluridine; Vidarabine; Virology; Virus Diseases	1984
Therapy of viral infections. Bulletin of the New York Academy of Medicine, 1982, Volume: 58, Issue:8 Topics: Acyclovir; Amantadine; Antiviral Agents; Herpesviridae Infections; Humans; Idoxuridine; Influenza, Human; Trifluridine; Vidarabine; Virus Diseases	1982
The relative merits and drawbacks of new nucleoside analogues with clinical potential. The Journal of antimicrobial chemotherapy, 1984, Volume: 14 Suppl A Topics: Acyclovir; Animals; Antiviral Agents; Biotransformation; Bromodeoxyuridine; Cytarabine; DNA-Directed RNA Polymerases; Ganciclovir; Humans; Idoxuridine; Nucleic Acid Synthesis Inhibitors; Nucleic Acids; Nucleosides; Ribavirin; Trifluridine; Vidarabine; Viruses	1984
Management of acyclovir-resistant herpes simplex and varicella-zoster virus infections. Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Algorithms; Drug Resistance, Microbial; Female; Foscarnet; Herpes Simplex; Herpes Zoster; Herpesviridae Infections; Herpesvirus 3, Human; Humans; Immunocompromised Host; Male; Recurrence; Simplexvirus; Trifluridine; Vidarabine	1994
The impact of the herpetic eye disease studies on the management of herpes simplex virus ocular infections. Current opinion in ophthalmology, 1999, Volume: 10, Issue:4 Topics: Acyclovir; Administration, Oral; Antiviral Agents; Corneal Stroma; Humans; Iritis; Keratitis, Herpetic; Prednisolone; Randomized Controlled Trials as Topic; Recurrence; Trifluridine	1999
Management of acyclovir-resistant herpes simplex virus. Dermatologic clinics, 2003, Volume: 21, Issue:2 Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Stomatitis, Herpetic; Trifluridine; Vidarabine	2003
[The latest in herpes simplex keratitis therapy]. Journal francais d'ophtalmologie, 2004, Volume: 27, Issue:5 Topics: Acyclovir; Antiviral Agents; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Trifluridine	2004
Herpes simplex virus keratitis in children. American journal of ophthalmology, 2004, Volume: 138, Issue:3 Topics: Acyclovir; Adolescent; Amblyopia; Antiviral Agents; Child; Child, Preschool; Cohort Studies; Corneal Stroma; Epithelium, Corneal; Herpesvirus 1, Human; Humans; Keratitis, Herpetic; Recurrence; Retrospective Studies; Trifluridine; Vidarabine	2004
Viral infections affecting the skin in organ transplant recipients: epidemiology and current management strategies. American journal of clinical dermatology, 2006, Volume: 7, Issue:1 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Administration Schedule; Epstein-Barr Virus Infections; Famciclovir; Foscarnet; Herpes Zoster; Herpesviridae Infections; Humans; Immunocompromised Host; Molluscum Contagiosum; Organ Transplantation; Organophosphonates; Papillomavirus Infections; Skin Diseases, Viral; Trifluridine; Valacyclovir; Valine	2006
Management of herpes simplex virus epithelial keratitis. Current opinion in ophthalmology, 2018, Volume: 29, Issue:4 Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Disease Models, Animal; Epithelial Cells; Epithelium, Corneal; Eye Infections, Viral; Ganciclovir; Humans; Keratitis, Herpetic; Ointments; Ophthalmic Solutions; Trifluridine	2018

Trials

17 trial(s) available for trifluridine and acyclovir

Article	Year
A comparison between acyclovir and trifluorothymidine ophthalmic ointment in the treatment of epithelial dendritic keratitis. A double blind, randomized parallel group trial. Acta ophthalmologica, 1989, Volume: 67, Issue:1 Topics: Acyclovir; Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Ointments; Ophthalmic Solutions; Random Allocation; Trifluridine	1989
Therapy for human herpesvirus infections. A perspective. The Alabama journal of medical sciences, 1985, Volume: 22, Issue:2 Topics: Acyclovir; Adult; Antiviral Agents; Chickenpox; Clinical Trials as Topic; Encephalitis; Herpes Simplex; Herpes Zoster; Herpesviridae Infections; Humans; Idoxuridine; Infant, Newborn; Infant, Newborn, Diseases; Keratitis, Dendritic; Trifluridine; Vidarabine	1985
Basic biochemical and pharmacological aspects of antiviral agents. Antiviral research, 1985, Volume: Suppl 1 Topics: Acyclovir; Amantadine; Antiviral Agents; Bone Marrow Transplantation; Chemical Phenomena; Chemistry; Clinical Trials as Topic; DNA, Viral; Herpesviridae; Herpesviridae Infections; Humans; Idoxuridine; Influenza A virus; Influenza, Human; Keratitis, Dendritic; RNA, Viral; S-Adenosylhomocysteine; Thymidine Kinase; Trifluridine; Vidarabine; Viral Proteins; Virus Diseases	1985
[Acyclovir versus trifluorothymidine in the therapy of stromal herpes keratitis]. Klinische Monatsblatter fur Augenheilkunde, 1986, Volume: 189, Issue:4 Topics: Acyclovir; Adult; Aged; Child, Preschool; Clinical Trials as Topic; Corneal Stroma; Cortisone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Random Allocation; Thymidine; Trifluridine	1986
[Combination interferon-trifluorothymidine in the treatment of herpetic keratitis]. Bulletins et memoires de la Societe francaise d'ophtalmologie, 1982, Volume: 94 Topics: Acyclovir; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Interferons; Keratitis, Dendritic; Male; Thymidine; Trifluridine	1982
Acyclovir in herpes simplex keratitis. The Journal of infection, 1983, Volume: 6, Issue:1 Suppl Topics: Acyclovir; Clinical Trials as Topic; Humans; Idoxuridine; Interferons; Keratitis, Dendritic; Trifluridine; Vidarabine	1983
Antiviral drugs 1983. The Medical clinics of North America, 1983, Volume: 67, Issue:5 Topics: Acyclovir; Amantadine; Antiviral Agents; Clinical Trials as Topic; Female; Herpes Genitalis; Herpes Simplex; Humans; Idoxuridine; Influenza, Human; Interferons; Keratitis, Dendritic; Male; Ribavirin; Rimantadine; Trifluridine; Vidarabine	1983
[Acyclovir and trifluorothymidine in herpetic kerato-uveitis. A comparative clinical study. Indications for corticoid therapy]. Journal francais d'ophtalmologie, 1984, Volume: 7, Issue:2 Topics: Acyclovir; Adrenal Cortex Hormones; Clinical Trials as Topic; Corneal Ulcer; Female; Humans; Keratitis, Dendritic; Male; Middle Aged; Random Allocation; Thymidine; Trifluridine; Uveitis; Uveitis, Anterior	1984
Aciclovir and trifluorothymidine in herpetic keratitis. Preliminary report of a multicentered trial. Documenta ophthalmologica. Advances in ophthalmology, 1981, Mar-20, Volume: 50, Issue:2 Topics: Acyclovir; Animals; Clinical Trials as Topic; Double-Blind Method; Guanine; Humans; Keratitis, Dendritic; Rabbits; Thymidine; Trifluridine	1981
Multicenter trial of acyclovir and trifluorothymidine in herpetic keratitis. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Antiviral Agents; Clinical Trials as Topic; Female; Guanine; Humans; Keratitis, Dendritic; Male; Thymidine; Trifluridine	1982
Acyclovir and trifluorothymidine in herpetic keratitis: a multicentre trial. The British journal of ophthalmology, 1982, Volume: 66, Issue:8 Topics: Acyclovir; Antiviral Agents; Clinical Trials as Topic; Double-Blind Method; Female; Guanine; Humans; Keratitis, Dendritic; Male; Middle Aged; Thymidine; Time Factors; Trifluridine	1982
Herpetic Eye Disease Study. A controlled trial of oral acyclovir for herpes simplex stromal keratitis. Ophthalmology, 1994, Volume: 101, Issue:12 Topics: Acyclovir; Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Keratitis, Herpetic; Male; Middle Aged; Patient Compliance; Prednisolone; Prospective Studies; Regression Analysis; Treatment Outcome; Trifluridine; United States; Visual Acuity	1994
Efficacy of four antiviral agents in the treatment of uncomplicated herpetic keratitis. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1995, Volume: 30, Issue:5 Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Double-Blind Method; Humans; Idoxuridine; Keratitis, Herpetic; Ointments; Treatment Failure; Trifluridine	1995
Pilot study of topical trifluridine for the treatment of acyclovir-resistant mucocutaneous herpes simplex disease in patients with AIDS (ACTG 172). AIDS Clinical Trials Group. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Jun-01, Volume: 12, Issue:2 Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chronic Disease; Drug Resistance, Microbial; Female; Herpes Simplex; Humans; Male; Middle Aged; Pilot Projects; Safety; Trifluridine	1996
A controlled trial of oral acyclovir for iridocyclitis caused by herpes simplex virus. The Herpetic Eye Disease Study Group. Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:9 Topics: Acyclovir; Administration, Oral; Administration, Topical; Anti-Inflammatory Agents; Antiviral Agents; Corneal Stroma; Female; Follow-Up Studies; Herpes Simplex; Herpesvirus 1, Human; Humans; Iridocyclitis; Keratitis, Herpetic; Male; Middle Aged; Ophthalmic Solutions; Patient Compliance; Prednisolone; Treatment Failure; Treatment Outcome; Trifluridine	1996
Risk factors for herpes simplex virus epithelial keratitis recurring during treatment of stromal keratitis or iridocyclitis. Herpetic Eye Disease Study Group. The British journal of ophthalmology, 1996, Volume: 80, Issue:11 Topics: Acyclovir; Anti-Inflammatory Agents; Antiviral Agents; Drug Therapy, Combination; Endothelium, Corneal; Female; Humans; Iridocyclitis; Keratitis, Dendritic; Keratitis, Herpetic; Male; Prednisolone; Recurrence; Risk Factors; Trifluridine	1996
Slitlamp biomicroscopy and photographic image analysis of herpes simplex virus stromal keratitis. Archives of ophthalmology (Chicago, Ill. : 1960), 2009, Volume: 127, Issue:2 Topics: Acyclovir; Antiviral Agents; Corneal Stroma; Cross-Sectional Studies; Female; Humans; Image Processing, Computer-Assisted; Keratitis, Herpetic; Male; Microscopy; Middle Aged; Photography; Trifluridine	2009

Other Studies

73 other study(ies) available for trifluridine and acyclovir

Article	Year
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3 Topics: Acyclovir; Animals; Anion Transport Proteins; Antiviral Agents; Carrier Proteins; Didanosine; In Vitro Techniques; Lamivudine; Oocytes; Rats; Stavudine; Transfection; Trifluridine; Xenopus laevis; Zalcitabine; Zidovudine	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set. Journal of medicinal chemistry, 2007, Apr-05, Volume: 50, Issue:7 Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship	2007
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells	2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Clinical effects and in vitro studies of trifluorothymidine combined with interferon-alpha for treatment of drug-resistant and -sensitive herpes simplex virus infections. The Journal of infectious diseases, 1992, Volume: 166, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Combined Modality Therapy; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Female; Foscarnet; Herpes Simplex; Humans; Interferon Type I; Male; Phosphonoacetic Acid; Recombinant Proteins; Recurrence; Simplexvirus; Trifluridine; Virus Replication	1992
Topical trifluridine for mucocutaneous acyclovir-resistant herpes simplex II in AIDS patient. Lancet (London, England), 1992, Oct-24, Volume: 340, Issue:8826 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Anus Diseases; Drug Resistance, Microbial; Herpes Genitalis; Humans; Male; Trifluridine	1992
The effect of HSV multiplication rate on antiviral drug efficacy in vitro. Antiviral research, 1991, Volume: 15, Issue:1 Topics: Acyclovir; Animals; Herpes Simplex; Simplexvirus; Trifluridine; Vero Cells; Viral Plaque Assay; Virus Replication	1991
Treatment of ocular disease in eczema herpeticum. American journal of ophthalmology, 1990, Sep-15, Volume: 110, Issue:3 Topics: Acyclovir; Administration, Topical; Adolescent; Adult; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Kaposi Varicelliform Eruption; Keratitis, Dendritic; Keratoconjunctivitis; Male; Trifluridine	1990
[Therapy of herpetic diseases of the anterior eye segment]. Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:6 Topics: Acyclovir; Antiviral Agents; Drug Therapy, Combination; Herpes Zoster; Humans; Interferons; Keratitis, Dendritic; Steroids; Thymidine; Trifluridine	1985
[Current treatment of herpes simplex-caused viral corneal infection]. Duodecim; laaketieteellinen aikakauskirja, 1986, Volume: 102, Issue:18 Topics: Acyclovir; Adrenal Cortex Hormones; Antiviral Agents; Humans; Idoxuridine; Interferons; Keratitis, Dendritic; Trifluridine	1986
In vitro susceptibility of feline herpesvirus-1 to vidarabine, idoxuridine, trifluridine, acyclovir, or bromovinyldeoxyuridine. American journal of veterinary research, 1989, Volume: 50, Issue:1 Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cats; Cell Line; Herpesviridae; Idoxuridine; Neutralization Tests; Trifluridine; Vidarabine	1989
Effect of choline esters and oleic acid on the penetration of acyclovir, estradiol, hydrocortisone, nitroglycerin, retinoic acid and trifluorothymidine across hairless mouse skin in vitro. Acta pharmaceutica Nordica, 1989, Volume: 1, Issue:5 Topics: Acyclovir; Animals; Choline; Estradiol; Female; Hydrocortisone; In Vitro Techniques; Mice; Mice, Hairless; Nitroglycerin; Oleic Acids; Skin Absorption; Tretinoin; Trifluridine	1989
Update on antiviral agents. Ophthalmology, 1985, Volume: 92, Issue:4 Topics: Acyclovir; Animals; Antiviral Agents; Biomechanical Phenomena; Eye Diseases; Ganglia; Herpes Simplex; Humans; Interferons; Rabbits; Recurrence; Simplexvirus; Trifluridine	1985
Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses. Antiviral research, 1985, Volume: 5, Issue:1 Topics: Acyclovir; Animals; Antiviral Agents; Deoxyuridine; DNA, Viral; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Encephalitis; Foscarnet; Herpes Simplex; Male; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Rabbits; Simplexvirus; Thymidine; Trifluridine; Vidarabine; Virus Replication	1985
2'-nor-cGMP, a new cyclic derivative of 2'NDG, inhibits HSV-1 replication in vitro and in the mouse keratitis model. Current eye research, 1987, Volume: 6, Issue:1 Topics: Acyclovir; Animals; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Eye; Ganciclovir; Guanine; Keratitis, Dendritic; Mice; Mice, Inbred BALB C; Organophosphorus Compounds; Simplexvirus; Trifluridine; Vero Cells; Virus Replication	1987
A mammalian cell line designed to test the mutagenic activity of anti-herpes nucleosides. International journal of cancer, 1987, Jul-15, Volume: 40, Issue:1 Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Division; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA, Viral; Idoxuridine; Mutagenicity Tests; Nucleosides; Simplexvirus; Thymidine Kinase; Transfection; Trifluridine	1987
Efficacy of topical treatment for herpes simplex virus infections: predictions from an index of drug characteristics in vitro. The Journal of infectious diseases, 1986, Volume: 153, Issue:1 Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Diffusion; Female; Guinea Pigs; Herpes Simplex; Idoxuridine; Pharmaceutical Vehicles; Skin Diseases; Trifluridine; Vidarabine	1986
Side effects in the treatment of herpetic keratitis. Current eye research, 1987, Volume: 6, Issue:1 Topics: Acyclovir; Conjunctivitis; Corneal Diseases; Dermatitis, Contact; Humans; Idoxuridine; Keratitis, Dendritic; Thymidine; Trifluridine; Vidarabine	1987
Retinal toxicity of combination antiviral drugs in an animal model. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1987, Volume: 22, Issue:6 Topics: Acyclovir; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Rabbits; Retina; Trifluridine; Vidarabine; Vitrectomy; Vitreous Body	1987
Effect of topical acyclovir therapy on experimental herpes simplex keratouveitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:9 Topics: Acyclovir; Administration, Topical; Animals; Iritis; Keratitis, Dendritic; Ointments; Rabbits; Thymidine; Trifluridine; Uveitis	1985
[Antiviral drugs]. La Revue du praticien, 1985, Oct-21, Volume: 35, Issue:47 Topics: Acyclovir; Amantadine; Antiviral Agents; Biguanides; Bromodeoxycytidine; Cytarabine; Deoxycytidine; Humans; Idoxuridine; Methisazone; Morpholines; Trifluridine; Vidarabine	1985
Virus chemotherapy: antiviral drugs and interferon. Antiviral research, 1984, Volume: 4, Issue:6 Topics: Acyclovir; Animals; Antiviral Agents; Drug Therapy, Combination; Herpes Simplex; Humans; Idoxuridine; Interferons; Keratitis, Dendritic; Rabbits; Trifluridine; Vidarabine	1984
Properties of antiviral agents. 1. Lancet (London, England), 1984, Sep-01, Volume: 2, Issue:8401 Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Evaluation Studies as Topic; Foscarnet; Herpesviridae; Humans; Idoxuridine; Phosphonoacetic Acid; Trifluridine; Vidarabine; Viruses	1984
Effects of acyclovir combined with other antiviral agents on human cytomegalovirus. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Antiviral Agents; Cell Line; Cytomegalovirus; Drug Evaluation, Preclinical; Drug Synergism; Foscarnet; Guanine; Humans; Interferons; Mathematics; Phosphonoacetic Acid; Trifluridine; Viral Plaque Assay	1982
Intraocular antiviral penetration. Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:12 Topics: Acyclovir; Administration, Topical; Antiviral Agents; Arabinonucleotides; Eye; Eye Diseases; Herpes Simplex; Humans; Simplexvirus; Thymidine; Trifluridine; Vidarabine Phosphate	1982
Combined chemotherapy of cutaneous herpes simplex infection of the guinea pig. Journal of medical virology, 1983, Volume: 12, Issue:2 Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Deoxyuridine; Drug Therapy, Combination; Female; Foscarnet; Guinea Pigs; Herpes Simplex; Idoxuridine; Male; Phosphonoacetic Acid; Skin Diseases, Infectious; Thymidine; Trifluridine; Vidarabine Phosphate	1983
Antimetabolite drug therapy in herpes simplex. Ophthalmology, 1980, Volume: 87, Issue:2 Topics: Acyclovir; Animals; Antimetabolites; Drug Therapy, Combination; Guanine; Humans; Idoxuridine; In Vitro Techniques; Keratitis, Dendritic; Rabbits; Simplexvirus; Trifluridine; Vidarabine	1980
The sensitivity of acyclovir-resistant mutants of herpes simplex virus to other antiviral drugs. The Journal of infectious diseases, 1981, Volume: 143, Issue:2 Topics: Acyclovir; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Drug Resistance, Microbial; Foscarnet; Guanine; Microbial Sensitivity Tests; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Trifluridine; Vidarabine	1981
Evaluation of the antiherpetic activity of acyclovir in rabbits. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cornea; Drug Resistance, Microbial; Guanine; Injections, Intravenous; Keratitis, Dendritic; Male; Rabbits; Simplexvirus; Time Factors; Trifluridine; Trigeminal Ganglion	1982
Chemotherapy of herpetic keratitis induced by acyclovir-resistant strains of herpes simplex virus type 1. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Animals; Antiviral Agents; Coformycin; Drug Resistance, Microbial; Drug Therapy, Combination; Guanine; Keratitis, Dendritic; Mutation; Pentostatin; Rabbits; Simplexvirus; Thymidine Kinase; Trifluridine; Vidarabine	1982
Different in vitro effects of dual combinations of anti-herpes simplex virus compounds. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chlorocebus aethiops; Drug Evaluation, Preclinical; Drug Interactions; Drug Synergism; Foscarnet; Guanine; Phosphonoacetic Acid; Simplexvirus; Trifluridine; Vidarabine	1982
Effectiveness of acycloguanosine and trifluorothymidine as inhibitors of cytomegalovirus infection in vitro. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Antiviral Agents; Cell Line; Cytomegalovirus; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Guanine; Humans; Thymidine; Trifluridine; Viral Plaque Assay	1982
Effect of acyclovir combined with other antiherpetic agents on varicella zoster virus in vitro. The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Guanine; Herpesvirus 3, Human; Idoxuridine; Trifluridine; Viral Plaque Assay	1982
Antiviral agents. American family physician, 1983, Volume: 27, Issue:1 Topics: Acyclovir; Amantadine; Antiviral Agents; Cytomegalovirus Infections; Drug Resistance, Microbial; Herpes Simplex; Humans; Idoxuridine; Trifluridine; Vidarabine	1983
Inhibition of human cytomegalovirus by trifluorothymidine. Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1 Topics: Acyclovir; Cytomegalovirus; Foscarnet; Humans; Interferon Type I; Lung; Phosphonoacetic Acid; Thymidine; Trifluridine; Virus Replication	1983
[Antiherpetics and their indications]. Nederlands tijdschrift voor geneeskunde, 1983, Apr-02, Volume: 127, Issue:14 Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Female; Herpesviridae Infections; Humans; Idoxuridine; Infant, Newborn; Male; Pregnancy; Trifluridine; Vidarabine	1983
[Herpes simplex viruses, their virologic diagnosis and therapeutic principles]. La Revue du praticien, 1983, Dec-01, Volume: 33, Issue:55 Topics: Acyclovir; Herpes Simplex; Humans; Idoxuridine; Simplexvirus; Trifluridine; Vidarabine	1983
[Comparative study of the effect of trifluorothymidine and acyclovir in herpetic anterior segmentitis]. Bulletin des societes d'ophtalmologie de France, 1983, Volume: 83, Issue:1 Topics: Acyclovir; Female; Humans; Keratitis, Dendritic; Male; Thymidine; Trifluridine; Uveitis, Anterior	1983
[Antiviral agents and cicatrization of the corneal stroma]. Journal francais d'ophtalmologie, 1983, Volume: 6, Issue:6-7 Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxycytidine; Cicatrix; Deoxycytidine; Keratitis, Dendritic; Rabbits; Tensile Strength; Trifluridine; Vidarabine; Wound Healing	1983
[Ocular herpes]. La Revue du praticien, 1983, Dec-01, Volume: 33, Issue:55 Topics: Acyclovir; Adolescent; Adult; Corneal Transplantation; Humans; Idoxuridine; Infant, Newborn; Keratitis, Dendritic; Trifluridine; Vidarabine	1983
Anti-metabolites in the management of herpes simplex keratitis. Metabolic and pediatric ophthalmology, 1980, Volume: 4, Issue:4 Topics: Acyclovir; Antiviral Agents; Guanine; Humans; Idoxuridine; Keratitis, Dendritic; Trifluridine; Vidarabine	1980
[Antiviral agents and corneal epithelium cicatrisation: study in rabbits (author's transl)]. Journal francais d'ophtalmologie, 1981, Volume: 4, Issue:12 Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxycytidine; Cornea; Deoxycytidine; Epithelium; Guanine; Idoxuridine; Rabbits; Trifluridine; Vidarabine; Wound Healing	1981
[Antiviral agents]. L'Annee therapeutique et clinique en ophtalmologie, 1982, Volume: 33 Topics: Acyclovir; Antiviral Agents; Bromodeoxycytidine; Deoxycytidine; Deoxyuracil Nucleotides; Eye Diseases; Humans; Idoxuridine; Ophthalmic Solutions; Trifluridine; Vidarabine; Virus Diseases	1982
New drugs in ophthalmology. Australian journal of ophthalmology, 1981, Volume: 9, Issue:3 Topics: Acyclovir; Antiviral Agents; Epinephrine; Eye Diseases; Glaucoma; Gliclazide; Humans; Hyaluronic Acid; Ophthalmology; Timolol; Trifluridine	1981
The treatment of acyclovir-resistant herpes zoster with trifluorothymidine and interferon alfa. Archives of dermatology, 1995, Volume: 131, Issue:1 Topics: Acyclovir; Administration, Topical; Combined Modality Therapy; Drug Resistance, Microbial; Herpes Zoster; Humans; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Recombinant Proteins; Skin Diseases, Viral; Treatment Outcome; Trifluridine	1995
Effect of genetically determined host factors on the efficacy of vidarabine, acyclovir and 5-trifluorothymidine in herpes simplex virus type 1 infection. Ophthalmic research, 1994, Volume: 26, Issue:2 Topics: Acyclovir; Animals; Embryo, Mammalian; Female; Fibroblasts; Genetic Variation; Herpesvirus 1, Human; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pregnancy; Trifluridine; Vero Cells; Vidarabine; Virus Replication	1994
In vitro sensitivity of macropodid herpesvirus 2 to selected anti-herpetic compounds. Journal of wildlife diseases, 1996, Volume: 32, Issue:1 Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxycytidine; Bromodeoxyuridine; Cell Line; Cytarabine; Deoxycytidine; Herpesviridae; Herpesviridae Infections; Idoxuridine; Macropodidae; Microbial Sensitivity Tests; Neutralization Tests; Thymidine; Trifluridine; Vidarabine	1996
Trifluorothymidine 0.5% ointment in the treatment of aciclovir-resistant mucocutaneous herpes simplex in AIDS. AIDS (London, England), 1996, Volume: 10, Issue:9 Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Resistance; Herpesviridae Infections; Humans; Male; Simplexvirus; Skin; Trifluridine; Tumor Virus Infections	1996
Idiopathic sectoral corneal endotheliitis. Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:4 Topics: Acyclovir; Adult; Antiviral Agents; Drug Therapy, Combination; Endothelium, Corneal; Glucocorticoids; Herpesvirus 1, Human; Humans; Keratitis, Herpetic; Male; Ophthalmic Solutions; Prednisolone; Trifluridine	1996
Drugs for non-HIV viral infections. The Medical letter on drugs and therapeutics, 1997, Aug-01, Volume: 39, Issue:1006 Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases	1997
Trifluridine, cidofovir, and penciclovir in the treatment of experimental herpetic keratitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:6 Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Female; Guanine; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Ointments; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine	1998
Comparative antiviral efficacies of cidofovir, trifluridine, and acyclovir in the HSV-1 rabbit keratitis model. Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:2 Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Female; Herpesvirus 1, Human; Keratitis, Dendritic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Trifluridine; Virus Replication; Virus Shedding	1999
Herpes study and resources. Treatment review, 1997, Issue:No 25 Topics: 2-Aminopurine; Acyclovir; Adult; Antiviral Agents; Biopolymers; Catechin; Clinical Trials as Topic; Complementary Therapies; Computer Communication Networks; Drug Resistance, Microbial; Famciclovir; Foscarnet; Gels; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV Infections; Humans; Middle Aged; Patient Selection; Trifluridine	1997
Drugs for non-HIV viral infections. The Medical letter on drugs and therapeutics, 2002, Feb-04, Volume: 44, Issue:1123 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Amantadine; Animals; Antiviral Agents; Cidofovir; Cytosine; Famciclovir; Foscarnet; Guanine; Herpesviridae Infections; Humans; Influenza, Human; Injections, Intravenous; Lamivudine; Organophosphonates; Organophosphorus Compounds; Rats; Ribavirin; Rimantadine; Thionucleotides; Trifluridine; Valacyclovir; Valine	2002
In vivo antiviral efficacy of a dipeptide acyclovir prodrug, val-val-acyclovir, against HSV-1 epithelial and stromal keratitis in the rabbit eye model. Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:6 Topics: Acyclovir; Animals; Antiviral Agents; Aqueous Humor; Biological Availability; Chlorocebus aethiops; Cornea; Corneal Stroma; Disease Models, Animal; Drug Evaluation, Preclinical; Epithelium, Corneal; Herpesvirus 1, Human; Keratitis, Herpetic; Prodrugs; Rabbits; Trifluridine; Valacyclovir; Valine	2003
New onset of herpes simplex virus epithelial keratitis after penetrating keratoplasty. American journal of ophthalmology, 2004, Volume: 137, Issue:3 Topics: Acyclovir; Administration, Oral; Administration, Topical; Adult; Aged; Antiviral Agents; Corneal Diseases; Epithelial Cells; Epithelium, Corneal; Female; Humans; Keratitis, Dendritic; Keratoplasty, Penetrating; Male; Middle Aged; Recurrence; Retrospective Studies; Trifluridine	2004
Management of ophthalmic zoster mucous plaque keratopathy: report of three cases. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2004, Volume: 39, Issue:1 Topics: 2-Aminopurine; Acyclovir; Adult; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Female; Herpes Zoster Ophthalmicus; Humans; Keratitis, Dendritic; Male; Middle Aged; Trifluridine	2004
[Herpetic keratitis. Clinical and therapeutic aspects]. Oftalmologia (Bucharest, Romania : 1990), 1997, Volume: 41, Issue:2 Topics: Acyclovir; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Antiviral Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Idoxuridine; Infant; Infant, Newborn; Keratitis, Herpetic; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Trifluridine	1997
Ocular complications in the Department of Defense Smallpox Vaccination Program. Ophthalmology, 2004, Volume: 111, Issue:11 Topics: Acyclovir; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antiviral Agents; Conjunctival Diseases; Corneal Diseases; Eye Infections, Viral; Eyelid Diseases; Female; Humans; Immunization Programs; Incidence; Infection Control; Male; Middle Aged; Military Medicine; Military Personnel; Retrospective Studies; Smallpox Vaccine; Trifluridine; United States; Vaccination; Vaccinia	2004
Herpes simplex keratitis misdiagnosed as rheumatoid arthritis-related peripheral ulcerative keratitis. Cornea, 2005, Volume: 24, Issue:8 Topics: Acyclovir; Aged; Antiviral Agents; Arthritis, Rheumatoid; Cornea; Corneal Ulcer; Diagnosis, Differential; Diagnostic Errors; Female; Follow-Up Studies; Herpesvirus 1, Human; Humans; Keratitis, Herpetic; Male; Microscopy, Electron, Transmission; Middle Aged; RNA, Viral; Trifluridine	2005
Imiquimod 5% cream for the treatment of recurrent, acyclovir-resistant genital herpes. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Feb-15, Volume: 42, Issue:4 Topics: Acyclovir; Administration, Topical; Aged; Aminoquinolines; Antiviral Agents; Arthritis, Rheumatoid; Drug Resistance, Viral; Emollients; Female; Foscarnet; Herpes Genitalis; Humans; Imiquimod; Infusions, Intravenous; Treatment Outcome; Trifluridine; Valacyclovir; Valine	2006
Is herpes simplex virus keratitis a different disease in children? Clinical & experimental optometry, 2008, Volume: 91, Issue:1 Topics: Acyclovir; Antiviral Agents; Child; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Keratitis, Herpetic; Ophthalmic Solutions; Sensory Deprivation; Severity of Illness Index; Trifluridine	2008
Collision induced dissociation studies of alkali metal adducts of tetracyclines and antiviral agents by electrospray ionization, hydrogen/deuterium exchange and multiple stage mass spectrometry. European journal of mass spectrometry (Chichester, England), 2008, Volume: 14, Issue:5 Topics: Acyclovir; Antiviral Agents; Deoxyuridine; Deuterium Exchange Measurement; Metals, Alkali; Purines; Spectrometry, Mass, Electrospray Ionization; Tetracyclines; Trifluridine; Vidarabine; Vidarabine Phosphate; Zidovudine	2008
Inhibition of viral replication in vitro by antiviral-treated amniotic membrane. Possible use of amniotic membrane as drug-delivering tool. The British journal of ophthalmology, 2011, Volume: 95, Issue:1 Topics: Acyclovir; Amnion; Animals; Antiviral Agents; Chlorocebus aethiops; Colony Count, Microbial; Drug Carriers; Humans; Simplexvirus; Trifluridine; Vero Cells; Virus Replication	2011
Unilateral keratitis following death of a twin as the presenting sign of herpetic infection in a neonate. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2011, Volume: 15, Issue:5 Topics: Acyclovir; Adolescent; Antiviral Agents; Cesarean Section; Fatal Outcome; Female; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Infant, Newborn; Keratitis, Herpetic; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Trifluridine; Twins, Dizygotic; Young Adult	2011
Pediatric herpes simplex of the anterior segment: characteristics, treatment, and outcomes. Ophthalmology, 2012, Volume: 119, Issue:10 Topics: 2-Aminopurine; Acyclovir; Administration, Topical; Adolescent; Age of Onset; Anterior Eye Segment; Antiviral Agents; Blepharitis; Child; Child, Preschool; Conjunctivitis, Viral; Eye Infections, Viral; Famciclovir; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Infant; Keratitis, Herpetic; Male; Ointments; Retrospective Studies; Trifluridine; Valacyclovir; Valine; Vidarabine	2012
Development of Herpes Simplex Virus Infectious Epithelial Keratitis During Oral Acyclovir Therapy and Response to Topical Antivirals. Cornea, 2016, Volume: 35, Issue:5 Topics: Acyclovir; Administration, Oral; Administration, Topical; Adolescent; Adult; Antiviral Agents; Blepharitis; Child; Conjunctivitis, Viral; Disease Progression; Epithelium, Corneal; Eye Infections, Viral; Female; Ganciclovir; Humans; Keratitis, Herpetic; Male; Retrospective Studies; Trifluridine	2016
Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2. Journal of receptor and signal transduction research, 2020, Volume: 40, Issue:6 Topics: Acyclovir; Ancitabine; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Evaluation, Preclinical; Guanine; Humans; Meropenem; Methyltransferases; Models, Molecular; Molecular Docking Simulation; Pandemics; Pneumonia, Viral; Protein Conformation; Ribitol; SARS-CoV-2; Trifluridine; User-Computer Interface; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins	2020
Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence. Investigative ophthalmology & visual science, 2023, Nov-01, Volume: 64, Issue:14 Topics: Acyclovir; Animals; Antiviral Agents; Blepharitis; Conjunctivitis; Cornea; Guinea Pigs; Herpes Simplex; Herpesvirus 1, Human; Humans; Rabbits; Trifluridine; Valacyclovir; Weight Loss	2023