Page last updated: 2024-09-05

trifluoromethionine and methionine

trifluoromethionine has been researched along with methionine in 19 studies

Compound Research Comparison

Studies
(trifluoromethionine)
Trials
(trifluoromethionine)
Recent Studies (post-2010)
(trifluoromethionine)
Studies
(methionine)
Trials
(methionine)
Recent Studies (post-2010) (methionine)
190527,4855305,020

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's3 (15.79)18.2507
2000's8 (42.11)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alston, TA; Bright, HJ1
Daub, E; Duewel, H; Honek, JF; Robinson, V1
Duewel, HS; Honek, JF1
Honek, JF; Lowther, WT; Matthews, BW; Sampson, PB; Zhang, Y1
Coombs, GH; Mottram, JC1
Daub, E; Duewel, HS; Honek, JF; Robinson, V1
Koga, T; Nakano, Y; Yoshimura, M1
Asai, T; Kobayashi, S; Nozaki, T; Takeuchi, T; Tokoro, M1
Berry, SM; Garner, DK; Honek, JF; Hwang, HJ; Lu, Y; Savelieff, MG; Vaughan, MD1
Harada, S; Nozaki, T; Sato, D; Yamagata, W1
Fujimura, S; Hirai, K; Kikuchi, Y; Nakayama, K; Ohara, N; Shibata, Y; Ueda, O1
Nozaki, T; Sato, D1
Ali, V; Kobayashi, S; Nozaki, T; Sato, D; Shibata, N; Soga, T; Suematsu, M; Takeuchi, T; Tokoro, G; Toru, T; Yamamoto, M; Yasui, H1
Holzberger, B; Marx, A; Möller, HM; Rubini, M1
Coombs, GH; Honek, JF; Moya, IA; Westrop, GD1
Furukawa, A; Nozaki, T; Penuliar, GM; Sato, D1
Furukawa, A; Husain, A; Nakada-Tsukui, K; Nozaki, T; Penuliar, GM; Sato, D1
Brender, JR; Kotov, NA; Krishnamoorthy, J; Marsh, EN; Ramamoorthy, A; Ruotolo, BT; Soper, MT; Suzuki, Y; Zhou, Y1
Brigaud, T; Chelain, E; Devillers, E; Gadais, C; Gasparik, V; Pytkowicz, J1

Reviews

1 review(s) available for trifluoromethionine and methionine

ArticleYear
Methionine gamma-lyase: the unique reaction mechanism, physiological roles, and therapeutic applications against infectious diseases and cancers.
    IUBMB life, 2009, Volume: 61, Issue:11

    Topics: Alkenes; Amino Acid Sequence; Anaerobiosis; Animals; Antineoplastic Agents; Apoptosis; Arabidopsis; Benzofurans; Carbon-Sulfur Lyases; Entamoeba histolytica; Humans; Methionine; Microbial Sensitivity Tests; Models, Molecular; Periodontal Diseases; Protozoan Infections; Trichomonas vaginalis

2009

Other Studies

18 other study(ies) available for trifluoromethionine and methionine

ArticleYear
Conversion of trifluoromethionine to a cross-linking agent by gamma-cystathionase.
    Biochemical pharmacology, 1983, Mar-01, Volume: 32, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Cross-Linking Reagents; Cystathionine gamma-Lyase; In Vitro Techniques; Kinetics; Lyases; Male; Methionine; Rats; Rats, Inbred Strains

1983
Incorporation of trifluoromethionine into a phage lysozyme: implications and a new marker for use in protein 19F NMR.
    Biochemistry, 1997, Mar-18, Volume: 36, Issue:11

    Topics: Bacteriophage lambda; Cloning, Molecular; Escherichia coli; Fluorine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methionine; Models, Molecular; Muramidase; Oligosaccharides; Protein Conformation; Recombinant Proteins

1997
CNBr/formic acid reactions of methionine- and trifluoromethionine-containing lambda lysozyme: probing chemical and positional reactivity and formylation side reactions by mass spectrometry.
    Journal of protein chemistry, 1998, Volume: 17, Issue:4

    Topics: Amino Acid Sequence; Bacteriophage lambda; Cyanogen Bromide; Formates; Indicators and Reagents; Methionine; Molecular Probes; Molecular Sequence Data; Muramidase; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

1998
Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
    Biochemistry, 1999, Nov-09, Volume: 38, Issue:45

    Topics: Amino Acid Substitution; Aminopeptidases; Crystallography, X-Ray; Escherichia coli; Hydrogen Bonding; Methionine; Methionyl Aminopeptidases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Phosphorus; Protein Conformation; Software; Structure-Activity Relationship

1999
Trifluoromethionine, a prodrug designed against methionine gamma-lyase-containing pathogens, has efficacy in vitro and in vivo against Trichomonas vaginalis.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:6

    Topics: Animals; Carbon-Sulfur Lyases; Cells, Cultured; Methionine; Prodrugs; Trichomonas vaginalis

2001
Elucidation of solvent exposure, side-chain reactivity, and steric demands of the trifluoromethionine residue in a recombinant protein.
    Biochemistry, 2001, Nov-06, Volume: 40, Issue:44

    Topics: Bacteriophage lambda; DNA Primers; Edetic Acid; Escherichia coli; Leucine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methionine; Models, Molecular; Muramidase; Mutation; Protein Conformation; Recombinant Proteins; Solvents

2001
L-Methionine-gamma-lyase, as a target to inhibit malodorous bacterial growth by trifluoromethionine.
    Biochemical and biophysical research communications, 2002, Apr-12, Volume: 292, Issue:4

    Topics: Animals; Bacteroidaceae Infections; Carbon-Sulfur Lyases; Disease Progression; Drug Evaluation, Preclinical; Female; Halitosis; Methionine; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Porphyromonas gingivalis; Sulfhydryl Compounds; Survival Rate; Virulence

2002
Identification and characterization of two isoenzymes of methionine gamma-lyase from Entamoeba histolytica: a key enzyme of sulfur-amino acid degradation in an anaerobic parasitic protist that lacks forward and reverse trans-sulfuration pathways.
    The Journal of biological chemistry, 2003, Oct-24, Volume: 278, Issue:43

    Topics: Amino Acids, Sulfur; Animals; Base Sequence; Carbon-Sulfur Lyases; Catalysis; Cytosol; Entamoeba histolytica; Hydrogen-Ion Concentration; Isoenzymes; Methionine; Molecular Sequence Data; Phylogeny; Protein Structure, Quaternary; Protozoan Proteins; Substrate Specificity

2003
Reduction potential tuning of the blue copper center in Pseudomonas aeruginosa azurin by the axial methionine as probed by unnatural amino acids.
    Journal of the American Chemical Society, 2006, Dec-13, Volume: 128, Issue:49

    Topics: Amino Acids; Azurin; Copper; Hydrogen Bonding; Ligands; Methionine; Models, Molecular; Norleucine; Oxidation-Reduction; Protein Conformation; Pseudomonas aeruginosa; Selenomethionine; Spectrum Analysis

2006
Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis.
    The FEBS journal, 2008, Volume: 275, Issue:3

    Topics: Amebiasis; Animals; Base Sequence; Carbon-Sulfur Lyases; Cysteine; Entamoeba histolytica; Isoenzymes; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protozoan Proteins; Recombinant Proteins; Sequence Alignment; Substrate Specificity

2008
Porphyromonas gingivalis mutant defective in a putative extracytoplasmic function sigma factor shows a mutator phenotype.
    Oral microbiology and immunology, 2009, Volume: 24, Issue:5

    Topics: Adhesins, Bacterial; Bacterial Proteins; Blotting, Southern; Chronic Periodontitis; Cysteine Endopeptidases; Gingipain Cysteine Endopeptidases; Hemagglutinins; Humans; Methionine; Mutation; Phenotype; Porphyromonas gingivalis; Reverse Transcriptase Polymerase Chain Reaction; Sigma Factor

2009
Cytotoxic effect of amide derivatives of trifluoromethionine against the enteric protozoan parasite Entamoeba histolytica.
    International journal of antimicrobial agents, 2010, Volume: 35, Issue:1

    Topics: Administration, Oral; Amides; Animals; Antiprotozoal Agents; Cricetinae; Cricetulus; Entamoeba histolytica; Entamoebiasis; Inhibitory Concentration 50; Liver Abscess; Methionine; Metronidazole; Molecular Structure; Quantitative Structure-Activity Relationship

2010
A highly active DNA polymerase with a fluorous core.
    Angewandte Chemie (International ed. in English), 2010, Feb-08, Volume: 49, Issue:7

    Topics: DNA; DNA-Directed DNA Polymerase; Magnetic Resonance Spectroscopy; Methionine; Protein Engineering

2010
Mechanistic studies on the enzymatic processing of fluorinated methionine analogues by Trichomonas vaginalis methionine γ-lyase.
    The Biochemical journal, 2011, Sep-15, Volume: 438, Issue:3

    Topics: Carbon-Sulfur Lyases; Escherichia coli; Kinetics; Methionine; Trichomonas vaginalis

2011
Mechanism of trifluoromethionine resistance in Entamoeba histolytica.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:9

    Topics: Animals; Antiprotozoal Agents; Blotting, Western; Carbon-Sulfur Lyases; Cell Adhesion; CHO Cells; Cricetinae; Cricetulus; Culture Media; Drug Resistance; Electrophoresis, Agar Gel; Entamoeba histolytica; Gene Expression Regulation; Gene Silencing; Kinetics; Methionine; Reverse Transcriptase Polymerase Chain Reaction

2011
Transcriptional and functional analysis of trifluoromethionine resistance in Entamoeba histolytica.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:2

    Topics: Antiprotozoal Agents; Carbon-Sulfur Lyases; Drug Resistance; Entamoeba histolytica; Gene Expression Profiling; Leucine-Rich Repeat Proteins; Methionine; Proteins; Protozoan Proteins

2012
Resolution of oligomeric species during the aggregation of Aβ1-40 using (19)F NMR.
    Biochemistry, 2013, Mar-19, Volume: 52, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Circular Dichroism; Humans; Methionine; Microscopy, Atomic Force; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Structure, Secondary; Solubility

2013
Probing the Outstanding Local Hydrophobicity Increases in Peptide Sequences Induced by Incorporation of Trifluoromethylated Amino Acids.
    Chembiochem : a European journal of chemical biology, 2018, 05-18, Volume: 19, Issue:10

    Topics: Alanine; Amino Acid Sequence; Cysteine; Halogenation; Hydrophobic and Hydrophilic Interactions; Methionine; Peptides

2018