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tridihexethyl and hypaconitine

tridihexethyl has been researched along with hypaconitine in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (14.00)18.2507
2000's11 (22.00)29.6817
2010's26 (52.00)24.3611
2020's6 (12.00)2.80

Authors

AuthorsStudies
Liu, WZ; Zuo, AL1
Tong, YY; Wang, K1
Tong, Y1
Chan, JC; Chan, TY; Chan, WW; Critchley, JA; Tomlinson, B; Tse, LK1
Boonhooi, O; Gonmori, K; Hayashi, M; Mizugaki, M; Saito, Y; Tagashira, A; Yoshioka, N1
Ohta, H; Seto, Y; Tsunoda, N1
Chen, YF; He, W; Zhu, FC1
Bi, P; Chen, D; Sun, A1
Chen, W; Duan, G; Guo, J; Huang, J; Lu, B; Sun, M1
Bae, K; Kang, SS; Kim, JS; Shim, SH; Son, KH1
Arita, H; Hanaoka, K; Hayashida, M; Sekiyama, H; Shu, H1
He, Y; Wang, Z; Wen, J; Xing, J1
Furuta, S; Hamajima, M; Hattori, S; Hirata, Y; Ishii, A; Kaneko, R; Seno, H; Watanabe, K1
Li, F; Liu, F; Qiao, YJ; Tan, YY; Yu, XH1
Itou, T; Kasahara, Y1
Chen, LJ; Duan, JG; Li, R; Tang, MH; Wang, XH; Wei, YQ; Zhang, F; Zhao, X1
Chen, H; Dong, F; Li, F; Li, H; Li, L; Sun, B; Wu, S; Yan, X; Zhang, Q1
Chang, H; Li, F; Li, Z; Sun, J; Zhang, S1
Chang, Q; Sun, L; Yang, Y; Zhang, L; Zhao, RH; Zhou, HY1
Chen, J; Shi, YP; Yang, Y1
Fang, L; He, Z; Li, Y; Wang, J; Xu, Y; Zhao, L; Zheng, N1
Gao, Y; Liang, QD; Rang, WQ; Wang, C; Wang, YG1
Gong, Y; Jiang, Z; Liu, Z; Lv, C; Tang, L; Wang, T; Yang, C; Ye, L; Zhou, J1
Bao, Y; Yang, F; Yang, X1
Liang, J; Liu, J; Liu, M; Xia, Y; Yang, C; Zhang, S1
Shen, H; Wu, J; Yao, N; Zhu, LY1
Feng, Q; Gao, S; Hu, M; Liu, W; Liu, Z; Yang, Z; Ye, L1
Li, N; Liu, Z; Ma, J; Sui, Z; Tsao, R1
Shi, YP; Zhang, HF1
Dong, X; Li, XM; Liu, SY; Liu, ZQ; Song, FR; Wang, SM1
Hou, DB; Liu, Z; Xu, CX; Yan, X; Yuan, XH1
Andreeva, TI; Chaykovskiy, AS; Dygai, AM; Gaydamovich, NN; Hrichkova, TY; Nesterova, YV; Povetieva, TN; Suslov, NI; Udut, EV; Zhdanov, VV1
Cui, P; Han, H; Wang, R; Yang, L1
Gao, S; Hu, M; Liu, W; Liu, Z; Wang, F; Yang, X; Yang, Z; Ye, L; Yin, T1
Fu, CM; He, Y; He, YX; Liao, W; Yan, D; Zhang, JM1
Du, J; Li, DH; Li, F; Ren, YZ; Sun, ZY; Wang, JB; Wen, RQ; Xiao, XH; Yan, D; Zhang, P; Zhao, X; Zhao, YL; Zhou, HY1
Cai, BC; Cui, XB; Li, JS; Li, W; Peng, WW; Wen, HM; Yang, GM; Zhang, YX1
Jiang, Y; Lu, YJ; Wang, ZH; Zhang, JZ; Zhang, PP1
Kazuma, K; Konno, K; Satake, M1
Aksinenko, SG; Krapivin, AV; Kravtsova, SS; Nesterova, YV; Povet'yeva, TN; Pushkarskii, SV; Schultz, EE; Suslov, NI; Zyuz'kov, GN1
Chen, H; Ho, A; Jaiswal, Y; Liang, Z; Wong, L; Yong, P; Zhao, Z1
Cao, Y; Xiong, YK; Yu, B1
Bian, B; Liu, H; Qiu, F; Wang, L; Zhao, H1
Chang, FR; Chen, BH; Jiang, YM; Lee, CW; Lin, YP; Liu, KT; Shiea, J; Su, H; Tsai, YH1
Dong, D; Gao, L; Lin, Y; Wang, S; Wu, B; Yang, Z; Zhou, Z1
Cong, J; Kang, L; Liu, W; Lyu, Q; Qi, X; Qin, X; Ruan, Y; Wu, C; Zhang, J1
Li, X; Liu, Z; Luo, G; Ou, X; Qi, X; Qu, W; Wang, Y; Xie, Y; Ying, M; Zhu, L; Zuo, H1
Dong, Z; Kennelly, EJ; Qian, J; Shi, Y; Wen, G; Zhao, D; Zhao, Y1
Gao, L; Lin, J; Lin, Y; Su, C; Wang, S; Wang, Z; Wu, B; Yang, Z1
Cui, J; Luo, H; Zan, F1

Reviews

1 review(s) available for tridihexethyl and hypaconitine

ArticleYear
Aconitine poisoning due to Chinese herbal medicines: a review.
    Veterinary and human toxicology, 1994, Volume: 36, Issue:5

    Topics: Aconitine; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Drugs, Chinese Herbal; Female; Heart Ventricles; Hong Kong; Humans; Male; Middle Aged; Neuromuscular Blocking Agents; Poisoning; Retrospective Studies; Sodium Channels

1994

Other Studies

49 other study(ies) available for tridihexethyl and hypaconitine

ArticleYear
[Construction and application of all-solid-state aconitine electrochemical detector in flow injection analysis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:4

    Topics: Aconitine; Drugs, Chinese Herbal; Electrochemistry; Flow Injection Analysis; Neuromuscular Blocking Agents

1992
[Determination of the main alkaloids in wu tou (aconite) by TLC-densitometry].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:5

    Topics: Aconitine; Aconitum; Chromatography, Thin Layer; Densitometry; Drugs, Chinese Herbal; Neuromuscular Blocking Agents

1990
[Determination of alkaloids in Aconite roots by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1990, Volume: 15, Issue:2

    Topics: Aconitine; Aconitum; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal

1990
A case of aconitine poisoning with analysis of aconitine alkaloids by GC/SIM.
    Forensic science international, 1996, Aug-15, Volume: 81, Issue:2-3

    Topics: Aconitine; Chromatography, Gas; Fatal Outcome; Forensic Medicine; Humans; Ion-Selective Electrodes; Male; Middle Aged; Plants, Edible; Poaceae; Poisoning

1996
Determination of Aconitum alkaloids in blood and urine samples. I. High-performance liquid chromatographic separation, solid-phase extraction and mass spectrometric confirmation.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Apr-11, Volume: 691, Issue:2

    Topics: Aconitine; Alkaloids; Chromatography, High Pressure Liquid; Drug Stability; Humans; Plants, Medicinal; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet

1997
[Determination of aconitine alkaloids in a pesticide--0.25% aconitine alkaloids mixed with emulsion by high performance liquid chromatography].
    Se pu = Chinese journal of chromatography, 2002, Volume: 20, Issue:3

    Topics: Aconitine; Aconitum; Chromatography, High Pressure Liquid; Emulsions; Insecticides; Reproducibility of Results

2002
[Determination of the aconitine alkaloids in traditional Chinese medicine chuanwu and caowu by high performance capillary electrophoresis(HPCE)].
    Se pu = Chinese journal of chromatography, 1999, Volume: 17, Issue:1

    Topics: Aconitine; Aconitum; Electrophoresis, Capillary; Ranunculaceae

1999
[The method for determination of aconitum alkaloids in Radix Aconiti Kusnezoffii].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2002, Volume: 25, Issue:12

    Topics: Aconitine; Aconitum; Alkaloids; Chromatography, High Pressure Liquid; Colorimetry; Coloring Agents; Drugs, Chinese Herbal; Pharmacognosy

2002
Alkaloidal constituents from Aconitum jaluense.
    Archives of pharmacal research, 2003, Volume: 26, Issue:9

    Topics: Aconitine; Aconitum; Alkaloids; Diterpenes; Korea; Plant Extracts; Plant Roots; Spectrophotometry, Infrared

2003
Effects of processed Aconiti tuber and its ingredient alkaloids on the development of antinociceptive tolerance to morphine.
    Journal of ethnopharmacology, 2006, Feb-20, Volume: 103, Issue:3

    Topics: Aconitine; Aconitum; Alkaloids; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Drugs, Chinese Herbal; Male; Mice; Morphine; Pain; Pain Measurement; Pain Threshold; Plant Tubers; Time Factors

2006
Quantitative determination of diterpenoid alkaloids in four species of Aconitum by HPLC.
    Journal of pharmaceutical and biomedical analysis, 2006, Mar-03, Volume: 40, Issue:4

    Topics: Aconitine; Aconitum; Alkaloids; Chromatography, High Pressure Liquid; Diterpenes; Drugs, Chinese Herbal; Plant Roots; Regression Analysis; Reproducibility of Results

2006
Sensitive analysis of aconitine, hypaconitine, mesaconitine and jesaconitine in human body fluids and Aconitum tubers by LC/ESI-TOF-MS.
    Journal of mass spectrometry : JMS, 2006, Volume: 41, Issue:6

    Topics: Aconitine; Aconitum; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Humans; Plant Tubers; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2006
[Determination of three kind of diester diterpenoid alkaloids (DDAs) in Aconitum carmichaeli and its processed products by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:14

    Topics: Aconitine; Aconitum; Alkaloids; Chromatography, High Pressure Liquid; Hot Temperature; Plant Roots; Plants, Medicinal; Quality Control; Reproducibility of Results; Technology, Pharmaceutical

2006
[Simultaneous determination of aconitine analogues in Aconitum plants and foods that caused food poisoning by liquid chromatography with tandem mass spectrometry].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2008, Volume: 49, Issue:2

    Topics: Aconitine; Aconitum; Chromatography, Liquid; Food Analysis; Foodborne Diseases; Tandem Mass Spectrometry

2008
Simultaneous quantitation of aconitine, mesaconitine, hypaconitine, benzoylaconine, benzoylmesaconine and benzoylhypaconine in human plasma by liquid chromatography-tandem mass spectrometry and pharmacokinetics evaluation of "SHEN-FU" injectable powder.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Oct-01, Volume: 873, Issue:2

    Topics: Aconitine; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Sensitivity and Specificity; Tandem Mass Spectrometry

2008
Metabolomic analysis of biofluids from rats treated with Aconitum alkaloids using nuclear magnetic resonance and gas chromatography/time-of-flight mass spectrometry.
    Analytical biochemistry, 2009, Dec-15, Volume: 395, Issue:2

    Topics: Aconitine; Aconitum; Alkaloids; Animals; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Metabolome; Metabolomics; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Wistar; Time Factors; Urinalysis

2009
[Changes of DDAs content affected by different processing time and its relationship with safety of processed Fuzi].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:9

    Topics: Aconitine; Alkaloids; Animals; Diterpenes; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Magnoliopsida; Male; Rats; Time Factors

2009
[Evaluation of the accumulation of dry substance and active componentsevaluation of the accumulation of dry substance and active components of Radix Aconiti Lateralis Praeparata].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:4

    Topics: Aconitine; Aconitum; Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Plant Roots; Quality Control; Seasons

2010
Determination of aconitine, hypaconitine and mesaconitine in urine using hollow fiber liquid-phase microextraction combined with high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Oct-15, Volume: 878, Issue:28

    Topics: Aconitine; Aconitum; Alkaloids; Chemical Fractionation; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Temperature

2010
Effect of (E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate on transdermal delivery of Aconitum alkaloids.
    Drug development and industrial pharmacy, 2011, Volume: 37, Issue:3

    Topics: Aconitine; Aconitum; Administration, Cutaneous; Animals; Excipients; Lipids; Male; Oleic Acids; Permeability; Rats; Rats, Wistar; Skin; Skin Absorption; Solubility

2011
[Analysis of chemical composition in the combination of monkshood and pinellia by UPLC/Q-TOFMS with multivariate statistical analysis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:10

    Topics: Aconitine; Aconitum; Chromatography, High Pressure Liquid; Drug Combinations; Drug Incompatibility; Multivariate Analysis; Pinellia; Plant Roots; Plant Tubers; Plants, Medicinal; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2010
Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species.
    Toxicology letters, 2011, Jul-04, Volume: 204, Issue:1

    Topics: Aconitine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Microsomes, Liver

2011
CE-electrochemiluminescence with ionic liquid for the facile separation and determination of diester-diterpenoid aconitum alkaloids in traditional Chinese herbal medicine.
    Electrophoresis, 2011, Volume: 32, Issue:12

    Topics: Aconitine; Aconitum; Drugs, Chinese Herbal; Electrophoresis, Capillary; Ethanol; Ether; Hydrogen-Ion Concentration; Ionic Liquids; Linear Models; Luminescent Measurements; Reproducibility of Results; Sensitivity and Specificity

2011
[Isolation and structure identification of C19 diterpenoid alkaloids from Aconitum carmichaeli by high-speed counter-current chromatography].
    Se pu = Chinese journal of chromatography, 2011, Volume: 29, Issue:5

    Topics: Aconitine; Aconitum; Alkaloids; Countercurrent Distribution; Diterpenes; Drugs, Chinese Herbal

2011
[The effect of the compatibility of Radix Aconiti Laterlis and radix glycyrrhizae on pharmacokinatic of aconitine, mesaconitine and hypacmitine in rat plasma].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:6

    Topics: Aconitine; Aconitum; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glycyrrhiza; Male; Mass Spectrometry; Pharmacokinetics; Plant Roots; Plants, Medicinal; Rats

2011
Development and validation of a highly sensitive UPLC-MS/MS method for simultaneous determination of aconitine, mesaconitine, hypaconitine, and five of their metabolites in rat blood and its application to a pharmacokinetics study of aconitine, mesaconiti
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:6

    Topics: Aconitine; Alkaloids; Animals; Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Female; Male; Rats; Rats, Wistar; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
Intestinal transport of pure diester-type alkaloids from an aconite extract across the Caco-2 cell monolayer model.
    Planta medica, 2012, Volume: 78, Issue:7

    Topics: Aconitine; Aconitum; Biological Availability; Biological Transport; Caco-2 Cells; Digoxin; Drug Interactions; Humans; Intestinal Absorption; Phytotherapy; Plant Extracts; Verapamil

2012
Preparation of Fe3O4 nanoparticle enclosure hydroxylated multi-walled carbon nanotubes for the determination of aconitines in human serum samples.
    Analytica chimica acta, 2012, Apr-29, Volume: 724

    Topics: Aconitine; Adsorption; Chromatography, High Pressure Liquid; Ferrosoferric Oxide; Humans; Hydrogen-Ion Concentration; Limit of Detection; Microscopy, Electron, Transmission; Nanoparticles; Nanotubes, Carbon; Serum; Signal-To-Noise Ratio; Solid Phase Extraction; Solvents

2012
[Determination of content changes of three diester-diterpenoid alkaloids in compatibility of radix aconiti laterlis preparata and Rhizoma pinelliae, Fructus trichosanthis, Bulbus fritillariae, Radix ampelopsis, Rhizoma bletillae by HPLC].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:12

    Topics: Aconitine; Aconitum; Alkaloids; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Fritillaria; Hot Temperature; Hydrogen-Ion Concentration; Orchidaceae; Pinellia; Plant Roots; Plants, Medicinal; Reproducibility of Results; Trichosanthes; Vitaceae

2011
[Extraction technology of diester-type alkaloids from Radix Aconiti lateralis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:11

    Topics: Aconitine; Aconitum; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ethanol; Plant Roots; Plants, Medicinal; Technology, Pharmaceutical; Temperature; Time Factors

2011
Regeneratory characteristics of complex extract and isolated diterpene alkaloids of Aconitum baikalense.
    Bulletin of experimental biology and medicine, 2012, Volume: 152, Issue:4

    Topics: Aconitine; Aconitum; Alkaloids; Animals; Cell Proliferation; Cells, Cultured; Colony-Forming Units Assay; Female; Fibroblasts; Mice; Mice, Inbred CBA; Plant Components, Aerial; Plant Extracts; Regeneration; Skin; Wound Healing

2012
Identification and determination of Aconitum alkaloids in Aconitum herbs and Xiaohuoluo pill using UPLC-ESI-MS.
    Molecules (Basel, Switzerland), 2012, Aug-27, Volume: 17, Issue:9

    Topics: Aconitine; Aconitum; Alkaloids; Diterpenes; Drugs, Chinese Herbal; Plant Roots; Principal Component Analysis; Spectrometry, Mass, Electrospray Ionization

2012
The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells.
    Toxicology letters, 2013, Feb-04, Volume: 216, Issue:2-3

    Topics: Aconitine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cyclosporine; Diketopiperazines; Dogs; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Madin Darby Canine Kidney Cells; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Propionates; Quinolines; Transfection; Verapamil

2013
Study on intestinal absorption and pharmacokinetic characterization of diester diterpenoid alkaloids in precipitation derived from fuzi-gancao herb-pair decoction for its potential interaction mechanism investigation.
    Journal of ethnopharmacology, 2013, May-02, Volume: 147, Issue:1

    Topics: Aconitine; Aconitum; Administration, Oral; Alkaloids; Animals; Biological Transport; Chemical Precipitation; Diterpenes; Drugs, Chinese Herbal; Esters; Intestinal Absorption; Intestine, Small; Male; Medicine, Chinese Traditional; Models, Biological; Perfusion; Phytotherapy; Plants, Medicinal; Rats; Rats, Sprague-Dawley

2013
[Rationality of the processing methods of aconiti lateralis radix (Fuzi) based on chemical analysis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:2

    Topics: Aconitine; Aconitum; Animals; Chromatography, High Pressure Liquid; Cluster Analysis; Drugs, Chinese Herbal; Male; Rats; Rats, Sprague-Dawley; Technology, Pharmaceutical

2013
The effects of Rhizoma Zingiberis on pharmacokinetics of six Aconitum alkaloids in herb couple of Radix Aconiti Lateralis-Rhizoma Zingiberis.
    Journal of ethnopharmacology, 2013, Jul-09, Volume: 148, Issue:2

    Topics: Aconitine; Aconitum; Alkaloids; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Diterpenes; Drugs, Chinese Herbal; Male; Mass Spectrometry; Medicine, Chinese Traditional; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Rhizome; Tandem Mass Spectrometry; Zingiber officinale

2013
[Determination of aconitine, hypaconitine and mesaconitine in Shenfu injection].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:10

    Topics: Aconitine; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Mass Spectrometry; Quality Control

2013
[Case of fatal aconite poisoning, and its background].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2013, Volume: 54, Issue:6

    Topics: Aconitine; Aconitum; Adult; Aged; Chromatography, High Pressure Liquid; Fatal Outcome; Female; Heart Arrest; Humans; Male; Middle Aged; Plant Leaves; Shock, Cardiogenic; Tachycardia, Ventricular; Tandem Mass Spectrometry

2013
Analgesic activity of diterpene alkaloids from Aconitum baikalensis.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:4

    Topics: Acetic Acid; Aconitine; Aconitum; Alkaloids; Analgesics; Animals; Animals, Outbred Strains; Arthritis, Experimental; Dipyrone; Freund's Adjuvant; Injections, Intraperitoneal; Mice; Pain; Plant Extracts; Rats; Seizures; Vocalization, Animal

2014
Distribution of toxic alkaloids in tissues from three herbal medicine Aconitum species using laser micro-dissection, UHPLC-QTOF MS and LC-MS/MS techniques.
    Phytochemistry, 2014, Volume: 107

    Topics: Aconitine; Aconitum; Alkaloids; Drugs, Chinese Herbal; Molecular Structure; Plant Roots

2014
Pharmacokinetics of aconitine-type alkaloids after oral administration of Fuzi (Aconiti Lateralis Radix Praeparata) in rats with chronic heart failure by microdialysis and ultra-high performance liquid chromatography-tandem mass spectrometry.
    Journal of ethnopharmacology, 2015, May-13, Volume: 165

    Topics: Aconitine; Aconitum; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Diterpenes; Drugs, Chinese Herbal; Heart Failure; Male; Microdialysis; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2015
Simultaneous high-performance liquid chromatography with tandem mass spectrometry quantification of six bioactive components in rat plasma after oral administration of Yougui pill.
    Journal of separation science, 2019, Volume: 42, Issue:10

    Topics: Aconitine; Administration, Oral; Alkaloids; Animals; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ions; Iridoid Glucosides; Male; Plant Extracts; Quality Control; Rats; Rats, Inbred Lew; Reproducibility of Results; Tandem Mass Spectrometry

2019
Rapid identification of herbal toxins using electrospray laser desorption ionization mass spectrometry for emergency care.
    Journal of food and drug analysis, 2019, Volume: 27, Issue:2

    Topics: Aconitine; Emergency Medical Services; Flavanones; Humans; Plants, Toxic; Pyridoxine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Toxins, Biological

2019
Circadian clock regulates metabolism and toxicity of Fuzi(lateral root of Aconitum carmichaeli Debx) in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 67

    Topics: Aconitine; Aconitum; Animals; ARNTL Transcription Factors; Chromatography, High Pressure Liquid; Circadian Clocks; Diterpenes; Drugs, Chinese Herbal; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microsomes, Liver; Plant Extracts; Toxicity Tests

2020
A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids.
    Journal of ethnopharmacology, 2020, Apr-24, Volume: 252

    Topics: Aconitine; Aconitum; Animals; Antiporters; Blood-Brain Barrier; Cell Line; Humans; Male; Mice, Inbred ICR; Organic Cation Transport Proteins; Protons; RNA, Small Interfering

2020
Mdr1a, Bcrp and Mrp2 regulate the efficacy and toxicity of mesaconitine and hypaconitine by altering their tissue accumulation and in vivo residence.
    Toxicology and applied pharmacology, 2020, 12-15, Volume: 409

    Topics: Aconitine; Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Transport; Brain; Gene Knockout Techniques; Male; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins

2020
    Journal of natural products, 2021, 03-26, Volume: 84, Issue:3

    Topics: Aconitine; Aconitum; Alkaloids; China; Chromatography, Liquid; Diterpenes; Drug Contamination; Drugs, Chinese Herbal; Mass Spectrometry; Medicine, Chinese Traditional; Molecular Structure; Plant Roots

2021
Pharmacokinetics-based chronoefficacy of Fuzi against chronic kidney disease.
    The Journal of pharmacy and pharmacology, 2021, Mar-08, Volume: 73, Issue:4

    Topics: Aconitine; Alkaloids; Animals; Anti-Inflammatory Agents; ARNTL Transcription Factors; Chronopharmacokinetics; Diterpenes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Kidney Function Tests; Mice; Mice, Knockout; Plant Roots; Protective Agents; Renal Insufficiency, Chronic; Treatment Outcome

2021
Effect of microneedle roller on promoting transdermal absorption of crossbow-medicine liquid via transdermal administration of Traditional Chinese Medicine and the safety of crossbow-medicine needle therapy: An experimental study.
    Journal of ethnopharmacology, 2023, Dec-05, Volume: 317

    Topics: Administration, Cutaneous; Anabasine; Animals; Chlorogenic Acid; Medicine, Chinese Traditional; Needles; Rats; Skin; Skin Absorption

2023