Compounds > triclabendazole sulfoxide
Page last updated: 2024-09-03

triclabendazole sulfoxide and verapamil

triclabendazole sulfoxide has been researched along with verapamil in 2 studies

Compound Research Comparison

Studies
(triclabendazole sulfoxide)		Trials
(triclabendazole sulfoxide)		Recent Studies (post-2010)
(triclabendazole sulfoxide)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
3011617,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomytriclabendazole sulfoxide (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brennan, GP; Fairweather, I; Hoey, E; Meaney, M; Savage, J; Trudgett, A2

Other Studies

2 other study(ies) available for triclabendazole sulfoxide and verapamil

ArticleYear
Effect of the P-glycoprotein inhibitor, R(+)-verapamil on the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica.
    Veterinary parasitology, 2013, Jul-01, Volume: 195, Issue:1-2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzimidazoles; Drug Resistance; Fasciola hepatica; Fascioliasis; Male; Microscopy, Electron, Scanning; Rats; Rats, Sprague-Dawley; Sulfoxides; Triclabendazole; Verapamil

2013
Increased susceptibility of a triclabendazole (TCBZ)-resistant isolate of Fasciola hepatica to TCBZ following co-incubation in vitro with the P-glycoprotein inhibitor, R(+)-verapamil.
    Parasitology, 2013, Volume: 140, Issue:10

    Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Fasciola hepatica; Male; Microscopy, Electron, Scanning; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfoxides; Triclabendazole; Verapamil

2013