Compounds > triclabendazole
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triclabendazole and ketoconazole

triclabendazole has been researched along with ketoconazole in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ballent, M; Lanusse, C; Lifschitz, A; Sallovitz, J; Scarcella, S; Virkel, G1
Alvarez, LI; Brennan, GP; Devine, C; Fairweather, I; Hoey, E; Lanusse, CE; Trudgett, A4

Other Studies

5 other study(ies) available for triclabendazole and ketoconazole

ArticleYear
Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep.
    Journal of veterinary pharmacology and therapeutics, 2009, Volume: 32, Issue:1

    Topics: Animals; Animals, Newborn; Anthelmintics; Area Under Curve; Benzimidazoles; Biological Availability; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Female; Ketoconazole; Methimazole; Piperonyl Butoxide; Random Allocation; Sheep; Triclabendazole

2009
Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole.
    Parasitology research, 2010, Volume: 107, Issue:2

    Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Fasciola hepatica; Ketoconazole; Microscopy, Electron, Scanning; Rats; Rats, Sprague-Dawley; Triclabendazole

2010
Enhancement of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica by co-treatment with ketoconazole.
    Veterinary parasitology, 2011, May-11, Volume: 177, Issue:3-4

    Topics: Animals; Benzimidazoles; Drug Synergism; Drug Therapy, Combination; Fasciola hepatica; Fascioliasis; Gastrointestinal Diseases; Ketoconazole; Male; Microscopy, Electron, Scanning; Rats; Rats, Sprague-Dawley; Triclabendazole

2011
Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.
    Parasitology research, 2011, Volume: 109, Issue:4

    Topics: Animals; Anthelmintics; Benzimidazoles; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance; Drug Synergism; Fasciola hepatica; Fascioliasis; Golgi Apparatus; Ketoconazole; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Mitochondria; NADP; Rats; Rats, Sprague-Dawley; Sulfoxides; Triclabendazole

2011
Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole.
    Veterinary parasitology, 2012, Feb-28, Volume: 184, Issue:1

    Topics: 14-alpha Demethylase Inhibitors; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Drug Synergism; Fasciola hepatica; Fascioliasis; Ketoconazole; Male; Microscopy, Electron, Transmission; Rats; Triclabendazole

2012