tricalcium phosphate has been researched along with simvastatin in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 23 (76.67) | 24.3611 |
| 2020's | 4 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Adah, F; Benghuzzi, H; England, B; Russell, G; Tucci, M | 1 |
| Brooks, RA; Clarke, SA; Ma, B; Rushton, N | 1 |
| Kasugai, S; Kihara, H; Machida, T; Nyan, M; Ohya, K; Sato, D | 1 |
| Hao, J; Kasugai, S; Kuroda, S; Miyahara, T; Noritake, K; Nyan, M; Rodriguez, R | 1 |
| Kasugai, S; Nyan, M; Ohya, K; Rojbani, H | 1 |
| Iafisco, M; Ito, T; Otsuka, M; Prat, M; Rimondini, L; Saito, M; Senna, M; Uchino, T | 1 |
| Li, JM; Li, YG; Si, M; Yin, H | 1 |
| Ben-Nissan, B; Chou, J; Ito, T; Milthorpe, B; Otsuka, M | 2 |
| Ben-Nissan, B; Bishop, D; Chou, J; Ito, T; Milthorpe, B; Otsuka, M | 1 |
| Ito, T; Makino, K; Otsuka, M; Takemasa, M | 1 |
| Engqvist, H; Karlsson Ott, M; Montazerolghaem, M | 1 |
| Govindan, R; Kavitha, M; Narasimhan, S; Varalakshmi, PR | 1 |
| Kim, MS; Lee, BT; Sadiasa, A | 1 |
| Jiang, XQ; Jin, YQ; Sun, XJ; Wu, YQ; Xu, LY; Zhang, XL | 1 |
| Ben-Nissan, B; Chou, J; Hao, J; Milthorpe, B; Otsuka, M | 1 |
| Dong, ZH; Gu, X; Guo, CC; Han, XQ; Wu, Z; Yu, XR | 1 |
| Fan, C; Jin, X; Liu, Y; Lv, L; Ou, M; Wu, G; Ye, H; Zhang, X; Zhou, Y | 1 |
| Ginebra, MP; Karlsson Ott, M; Kugiejko, K; Mestres, G; Öhman, C; Pastorino, D; Persson, C; Unosson, J | 1 |
| Aragonez, A; Bobinski, F; Cordeiro, MM; Corrêa, M; de Freitas, SF; dos Santos, AR; Encarnação, IC; Goldfeder, EM; Xavier, CC | 1 |
| Engqvist, H; Karlsson Ott, M; Melhus, H; Montazerolghaem, M; Rasmusson, A | 1 |
| Dinarvand, R; Eslami, H; Hooshmand, B; Jafarzadeh Kashi, TS; Khoshroo, K; Masaeli, R; Mashhadi Abbas, F; Rajabnejad, A; Rakhshan, V; Raz, M; Shahoon, H; Tahriri, M; Tayebi, L | 1 |
| Aragones, A; Corrêa, LR; Corrêa, M; Magini, RS; Marodin, A; Noronha Oliveira, M; Rau, LH | 1 |
| Ali, S; Bakry, S; Gouda, A; Helal, E; Yassin, S | 1 |
| Ge, Y; Jiang, W; Li, W; Liu, Y; Wang, L; Wu, G; Zhang, P; Zhang, X; Zhou, Y | 1 |
| Al-Naggar, IM; Alhamdi, JR; Hawley, KL; Kuhn, LT; Peng, T; Spiller, KL | 1 |
| Canal, C; Ginebra, MP; Guillem-Marti, J; Khurana, K; Mücklich, F; Soldera, F | 1 |
| Chang, HH; Chang, YJ; Lin, CP; Lin, TA; Yeh, CL | 1 |
| Aragones, Á; Cordeiro, MMR; da Cruz, ACC; de Souza Magini, R; Sordi, MB | 1 |
| Cui, X; Deng, X; Gao, Y; Hu, F; Jia, F; Lu, J; Pan, Z; Wang, X; Wu, Y; Xu, C; Yang, X; Zhang, X; Zhang, Z | 1 |
1 review(s) available for tricalcium phosphate and simvastatin
| Article | Year |
|---|---|
Coral exoskeletons as a precursor material for the development of a calcium phosphate drug delivery system for bone tissue engineering.
Topics: Animals; Anthozoa; Bone Substitutes; Calcium Phosphates; Drug Delivery Systems; Humans; Simvastatin; Tissue Engineering | 2013 |
1 trial(s) available for tricalcium phosphate and simvastatin
| Article | Year |
|---|---|
Ridge Preservation After Maxillary Third Molar Extraction Using 30% Porosity PLGA/HA/β-TCP Scaffolds With and Without Simvastatin: A Pilot Randomized Controlled Clinical Trial.
Topics: Alveolar Ridge Augmentation; Biocompatible Materials; Bone Substitutes; Calcium Phosphates; Collagen; Cone-Beam Computed Tomography; Durapatite; Female; Humans; Lactic Acid; Male; Maxilla; Minerals; Molar, Third; Pilot Projects; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Prospective Studies; Simvastatin; Tissue Scaffolds; Tooth Extraction; Young Adult | 2017 |
28 other study(ies) available for tricalcium phosphate and simvastatin
| Article | Year |
|---|---|
Effects of sustained release of statin by means of tricalcium phosphate lysine delivery system in defect and segmental femoral injuries on certain biochemical markers in vivo.
Topics: Animals; Biomarkers; Calcium Phosphates; Drug Carriers; Femoral Fractures; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin-Like Growth Factor II; Lysine; Male; Proteins; Rats; Rats, Sprague-Dawley; Simvastatin; Treatment Outcome | 2006 |
The effect of simvastatin on bone formation and ceramic resorption in a peri-implant defect model.
Topics: Animals; Bone Substitutes; Calcium Phosphates; Ceramics; Implants, Experimental; Male; Osteogenesis; Rats; Rats, Sprague-Dawley; Simvastatin; Time Factors | 2008 |
Effects of the combination with alpha-tricalcium phosphate and simvastatin on bone regeneration.
Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Biocompatible Materials; Bone Regeneration; Calcium Phosphates; Dose-Response Relationship, Drug; Drug Carriers; Drug Combinations; Osteogenesis; Rats; Rats, Wistar; Simvastatin; Skull | 2009 |
Molecular and tissue responses in the healing of rat calvarial defects after local application of simvastatin combined with alpha tricalcium phosphate.
Topics: Animals; Base Sequence; Biocompatible Materials; Bone Morphogenetic Protein 2; Bone Regeneration; Calcium Phosphates; Cell Movement; Cell Proliferation; Delayed-Action Preparations; DNA Primers; Drug Delivery Systems; Gene Expression Profiling; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Materials Testing; Osteoblasts; Rats; Rats, Wistar; RNA, Messenger; Simvastatin; Skull; Time Factors; Tissue Engineering; Transforming Growth Factor beta1; Up-Regulation | 2010 |
Evaluation of the osteoconductivity of α-tricalcium phosphate, β-tricalcium phosphate, and hydroxyapatite combined with or without simvastatin in rat calvarial defect.
Topics: Animals; Anticholesteremic Agents; Biocompatible Materials; Bone Regeneration; Bone Substitutes; Calcium Phosphates; Drug Carriers; Durapatite; Humans; Implants, Experimental; Male; Materials Testing; Rats; Rats, Wistar; Simvastatin; Skull; Tomography Scanners, X-Ray Computed | 2011 |
Preparation of injectable auto-forming alginate gel containing simvastatin with amorphous calcium phosphate as a controlled release medium and their therapeutic effect in osteoporosis model rat.
Topics: Alginates; Animals; Buffers; Calcium Phosphates; Catalysis; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Drug Delivery Systems; Female; Gels; Hypolipidemic Agents; Injections; Osteoporosis; Polymerization; Rats; Rats, Sprague-Dawley; Simvastatin | 2012 |
Simvastatin-loaded macroporous calcium phosphate cement: preparation, in vitro characterization, and evaluation of in vivo performance.
Topics: Animals; Bone and Bones; Bone Cements; Calcium Phosphates; Compressive Strength; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Materials Testing; Osteogenesis; Porosity; Prostheses and Implants; Rabbits; Simvastatin; Sodium Dodecyl Sulfate; X-Ray Diffraction | 2012 |
Simvastatin-loaded β-TCP drug delivery system induces bone formation and prevents rhabdomyolysis in OVX mice.
Topics: Animals; Calcium Phosphates; Delayed-Action Preparations; Diffusion; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Osteogenesis; Ovariectomy; Rhabdomyolysis; Simvastatin; Treatment Outcome | 2013 |
Controlled release of simvastatin from biomimetic β-TCP drug delivery system.
Topics: Apatites; Aquatic Organisms; Biomimetics; Body Fluids; Calcium Phosphates; Drug Delivery Systems; Foraminifera; Humans; Osteogenesis; Simvastatin; Spectroscopy, Fourier Transform Infrared | 2013 |
Preparation of calcium phosphate nanocapsules including simvastatin/deoxycholic acid assembly, and their therapeutic effect in osteoporosis model mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Bone Density Conservation Agents; Calcium Phosphates; Cell Line; Deoxycholic Acid; Disease Models, Animal; Drug Compounding; Drug Delivery Systems; Female; Humans; Hypolipidemic Agents; Mice; Mice, Inbred Strains; Micelles; Nanocapsules; Osteoporosis, Postmenopausal; Random Allocation; Simvastatin; Surface Properties; Surface-Active Agents | 2013 |
Sustained release of simvastatin from premixed injectable calcium phosphate cement.
Topics: Bone Cements; Calcium Phosphates; Cell Line, Tumor; Compressive Strength; Delayed-Action Preparations; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Osteogenesis; Simvastatin | 2014 |
Effect of statins with α-tricalcium phosphate on proliferation, differentiation, and mineralization of human dental pulp cells.
Topics: Adolescent; Adult; Alkaline Phosphatase; Aluminum Compounds; Atorvastatin; Biocompatible Materials; Biomarkers; Bone Morphogenetic Protein 2; Calcification, Physiologic; Calcium Compounds; Calcium Phosphates; Cell Adhesion; Cell Differentiation; Cell Proliferation; Dental Pulp; Dentin; Drug Combinations; Extracellular Matrix Proteins; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Odontoblasts; Osteogenesis; Osteonectin; Oxides; Phosphoproteins; Pyrroles; Sialoglycoproteins; Silicates; Simvastatin; Young Adult | 2013 |
The effectiveness of the controlled release of simvastatin from β-TCP macrosphere in the treatment of OVX mice.
Topics: Animals; Biomechanical Phenomena; Bone Density; Calcium Phosphates; Delayed-Action Preparations; Diaphyses; Female; Femur; Implants, Experimental; Mice; Osteogenesis; Ovariectomy; Simvastatin; Tissue Scaffolds; X-Ray Diffraction | 2016 |
Poly(lactide-co-glycolide acid)/biphasic calcium phosphate composite coating on a porous scaffold to deliver simvastatin for bone tissue engineering.
Topics: Biocompatible Materials; Bone and Bones; Calcium Phosphates; Cell Line; Compressive Strength; Delayed-Action Preparations; Humans; Polyglactin 910; Porosity; Simvastatin; Tissue Engineering | 2013 |
[Repair of calvarial defect using a tissue-engineered bone with simvastatin-loaded β-tricalcium phosphate scaffold and adipose derived stem cells in rabbits].
Topics: Adipose Tissue; Alkaline Phosphatase; Animals; Bone Regeneration; Calcium Phosphates; Cell Differentiation; Cells, Cultured; Osteogenesis; Rabbits; Simvastatin; Stem Cells; Wound Healing | 2013 |
[Experimental study of tissue-engineered bone constructed with simvastatin carried by PLGA/CPC and bone marrow stromal cells].
Topics: Alkaline Phosphatase; Bone Marrow Cells; Calcium Phosphates; Cell Differentiation; Lactic Acid; Mesenchymal Stem Cells; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Simvastatin; Tissue Engineering; Tissue Scaffolds | 2014 |
Bi-functionalization of a calcium phosphate-coated titanium surface with slow-release simvastatin and metronidazole to provide antibacterial activities and pro-osteodifferentiation capabilities.
Topics: Anti-Bacterial Agents; Calcium Phosphates; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Coated Materials, Biocompatible; Delayed-Action Preparations; Disk Diffusion Antimicrobial Tests; Humans; Kinetics; Mesenchymal Stem Cells; Metronidazole; Osteogenesis; Prostheses and Implants; Simvastatin; Surface Properties; Titanium | 2014 |
Changes in the drug release pattern of fresh and set simvastatin-loaded brushite cement.
Topics: Bone Cements; Calcium Phosphates; Simvastatin | 2016 |
Analysis of Bone Repair and Inflammatory Process Caused by Simvastatin Combined With PLGA+HA+βTCP Scaffold.
Topics: Animals; Bone Regeneration; Calcium Phosphates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Simvastatin; Skull; Tissue Scaffolds | 2016 |
Simvastatin-doped pre-mixed calcium phosphate cement inhibits osteoclast differentiation and resorption.
Topics: Animals; Bone Cements; Bone Marrow Cells; Bone Resorption; Calcium; Calcium Phosphates; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Liberation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Materials Testing; Mice; Osteoclasts; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin | 2016 |
Efficacy of the biomaterials 3wt%-nanostrontium-hydroxyapatite-enhanced calcium phosphate cement (nanoSr-CPC) and nanoSr-CPC-incorporated simvastatin-loaded poly(lactic-co-glycolic-acid) microspheres in osteogenesis improvement: An explorative multi-phase
Topics: Animals; Biocompatible Materials; Bone and Bones; Bone Diseases; Calcium Phosphates; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Humans; Hydroxyapatites; Lactic Acid; Male; Microspheres; Nanocomposites; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Rats; Rats, Sprague-Dawley; Simvastatin; Strontium | 2016 |
Maxillary sinus lift using osteoinductive simvastatin combined with β-TCP versus β-TCP - a comparative pilot study to evaluate simvastatin enhanced and accelerated bone formation.
Topics: Adult; Aged; Bone Substitutes; Calcium Phosphates; Cone-Beam Computed Tomography; Drug Therapy, Combination; Female; Humans; Male; Maxilla; Maxillary Sinus; Middle Aged; Pilot Projects; Simvastatin; Sinus Floor Augmentation | 2018 |
Human adipose-derived stem cells and simvastatin-functionalized biomimetic calcium phosphate to construct a novel tissue-engineered bone.
Topics: Animals; Bone Development; Bone Substitutes; Calcium Phosphates; Cells, Cultured; Drug Implants; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Nude; Osteoblasts; Osteogenesis; Simvastatin; Tissue Engineering; Tissue Scaffolds | 2018 |
Controlled M1-to-M2 transition of aged macrophages by calcium phosphate coatings.
Topics: Animals; Calcium Phosphates; Cellular Senescence; Coated Materials, Biocompatible; Dose-Response Relationship, Drug; Drug Delivery Systems; Gene Expression Regulation; Humans; Interferon-gamma; Kinetics; Macrophages; Male; Mice, Inbred C57BL; Simvastatin; THP-1 Cells; Time Factors | 2019 |
Injectable calcium phosphate foams for the delivery of Pitavastatin as osteogenic and angiogenic agent.
Topics: Biomimetic Materials; Bone Cements; Bone Substitutes; Bone Transplantation; Calcium Phosphates; Compressive Strength; Drug Liberation; Endothelial Progenitor Cells; Humans; Injections; Mechanical Tests; Mesenchymal Stem Cells; Osteogenesis; Quinolines; Simvastatin; X-Ray Microtomography | 2020 |
Development of calcium phosphate/calcium sulfate biphasic biomedical material with hyaluronic acid containing collagenase and simvastatin for vital pulp therapy.
Topics: Animals; Biocompatible Materials; Calcium Phosphates; Calcium Sulfate; Collagenases; Dental Pulp; Humans; Hyaluronic Acid; Phosphates; Simvastatin; X-Ray Microtomography | 2020 |
PLGA+HA/βTCP Scaffold Incorporating Simvastatin: A Promising Biomaterial for Bone Tissue Engineering.
Topics: Biocompatible Materials; Calcium Phosphates; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Simvastatin; Tissue Engineering; Tissue Scaffolds | 2021 |
Periostin-targeted SDSSD peptide decorated calcium phosphate nanocomposites incorporation with simvastatin for osteoporosis treatment.
Topics: Animals; Calcium Phosphates; Nanocomposites; Osteoporosis; Peptides; Simvastatin | 2023 |