Page last updated: 2024-08-17

tributyrin and butyric acid

tributyrin has been researched along with butyric acid in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's7 (29.17)18.2507
2000's1 (4.17)29.6817
2010's13 (54.17)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Riley, TV1
German, JB; Hickman, MA; Smith, JG1
Breitman, TR; Chen, ZX1
Newmark, HL; Young, CW1
Akyhani, N; Feng, P; Ge, L; Liau, G1
Breitman, TR; Chen, ZX; Taimi, M1
Carter, LC; German, JB; Mak, J; Tsau, J; Watkins, SM; Yamamoto, S1
Basak, G; Czajka, A; Giermasz, A; Hoser, G; Jakóbisiak, M; Jalili, A; Lewandowski, S; Makowski, M; Marczak, M; Młynarczuk, I; Nowis, D; Stok osa, T1
Chen, L; Chen, Z; Pan, J; Wang, W; Xue, Y1
Martín, D; Morán-Valero, MI; Reglero, G; Señoráns, FJ; Torres, CF1
de Conti, A; Heidor, R; Moreno, FS; Ong, TP; Ortega, JF1
Beland, FA; de Conti, A; Heidor, R; Koturbash, I; Kuroiwa-Trzmielina, J; Moreno, FS; Ong, TP; Pogribny, IP; Tryndyak, V1
de Conti, A; de Paiva, SA; Furtado, KS; Gioielli, LA; Heidor, R; Moreno, FS; Ortega, JF; Pogribny, IP; Purgatto, E; Ract, JN; Silva, RC; Tavares, PE1
Cadwallader, KR; Donovan, JD; Lee, Y1
Beland, FA; de Conti, A; Fernandes, LH; Furtado, KS; Heidor, R; Horst, MA; Moreno, FS; Ortega, JF; Pogribna, M; Pogribny, IP; Shpyleva, S; Tavares, PE; Tryndyak, V1
Bauer, L; Donovan, JD; Fahey, GC; Lee, Y1
Hendriks, WH; Kwakkel, RP; Moquet, PCA; Onrust, L; Salami, SA1
Behrendt, CL; Chanin, RB; Furtado de Carvalho, T; Gillis, CC; Hooper, LV; Hughes, ER; Santos, RL; Spiga, L; Winter, MG; Winter, SE; Zhu, W1
Andrade, FO; Farsky, SHP; Fernandes, LHG; Furtado, KS; Hebeda, CB; Heidor, R; Horst, MA; Miranda, MLP; Moreno, FS; Sandri, S; Yamamoto, RC1
Cha, S; Haase, MF; Jung, GY; Lee, D; Lim, HG; Stebe, KJ1
Kapás, L; Massie, AR; Millican, NS; Szentirmai, É1
Acquistapace, S; Cuenoud, B; Forbes-Blom, E; Patel, L; Patin, A; Wooster, TJ1
Belén Sanz-Martos, A; Cano, V; Del Olmo, N; Fernández-Felipe, J; Merino, B; Ruiz-Gayo, M1
Chen, Z; Han, Y; Lan, T; Li, H; Ma, X; Song, Y; Tao, M; Wang, C; Xu, Z; Yang, N; Zhao, H1

Reviews

2 review(s) available for tributyrin and butyric acid

ArticleYear
Butyrate and phenylacetate as differentiating agents: practical problems and opportunities.
    Journal of cellular biochemistry. Supplement, 1995, Volume: 22

    Topics: Animals; Antimetabolites, Antineoplastic; Butyrates; Butyric Acid; Cell Differentiation; Drug Synergism; Humans; Mice; Phenylacetates; Rats; Triglycerides

1995
Anticarcinogenic actions of tributyrin, a butyric acid prodrug.
    Current drug targets, 2012, Volume: 13, Issue:14

    Topics: Animals; Anticarcinogenic Agents; Butyric Acid; Cell Line, Tumor; Humans; Neoplasms; Prodrugs; Triglycerides

2012

Other Studies

22 other study(ies) available for tributyrin and butyric acid

ArticleYear
A note on hydrolysis of tributyrin by Branhamella and Neisseria.
    The Journal of applied bacteriology, 1987, Volume: 62, Issue:6

    Topics: Butyrates; Butyric Acid; Chromatography, Gas; Culture Media; Hydrolysis; Moraxella; Neisseria; Triglycerides

1987
Incorporation of tributyrin enhances the expression of a reporter gene in primary and immortalized cell lines.
    BioTechniques, 1995, Volume: 18, Issue:5

    Topics: 3T3 Cells; Acetylation; Animals; Butyrates; Butyric Acid; Cats; Cells, Cultured; Dogs; Gene Expression; Genes, Reporter; Histones; Liposomes; Liver; Luciferases; Mice; Promoter Regions, Genetic; Rats; Transfection; Triglycerides; Tumor Cells, Cultured

1995
Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy.
    Cancer research, 1994, Jul-01, Volume: 54, Issue:13

    Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Drug Interactions; Drug Screening Assays, Antitumor; Friend murine leukemia virus; Glycerides; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Prodrugs; Triglycerides; Tumor Cells, Cultured

1994
Sodium butyrate is a potent modulator of smooth muscle cell proliferation and gene expression.
    Cell proliferation, 1996, Volume: 29, Issue:5

    Topics: Adenosine Monophosphate; Animals; Aorta; Butyrates; Butyric Acid; Cell Cycle; Cell Differentiation; Cell Division; DNA; Gene Expression Regulation; Genes, fos; Genes, myc; Genes, ras; Membrane Glycoproteins; Muscle Proteins; Muscle, Smooth, Vascular; Rabbits; Thrombospondins; Triglycerides

1996
Potentiation of retinoic acid-induced differentiation of human acute promyelocytic leukemia NB4 cells by butyric acid, tributyrin, and hexamethylene bisacetamide.
    Oncology research, 1998, Volume: 10, Issue:2

    Topics: Acetamides; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Drug Synergism; Humans; Leukemia, Promyelocytic, Acute; Tretinoin; Triglycerides; Tumor Cells, Cultured

1998
Butyric acid and tributyrin induce apoptosis in human hepatic tumour cells.
    The Journal of dairy research, 1999, Volume: 66, Issue:4

    Topics: Acetylation; Apoptosis; Butyric Acid; Cell Nucleus; DNA Fragmentation; Histones; Humans; Liver Neoplasms; Microscopy, Fluorescence; Triglycerides; Tumor Cells, Cultured

1999
Antitumor activity of tributyrin in murine melanoma model.
    Cancer letters, 2001, Mar-26, Volume: 164, Issue:2

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Butyric Acid; Cell Cycle; Cell Division; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neovascularization, Pathologic; Prodrugs; Time Factors; Triglycerides; Tumor Cells, Cultured

2001
Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells.
    Chinese medical journal, 1999, Volume: 112, Issue:4

    Topics: Butyric Acid; Cell Transformation, Neoplastic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Oncogene Proteins, Fusion; Prodrugs; Stereoisomerism; Translocation, Genetic; Tretinoin; Triglycerides; Tumor Cells, Cultured

1999
In vitro intestinal bioaccessibility of alkylglycerols versus triacylglycerols as vehicles of butyric acid.
    Lipids, 2011, Volume: 46, Issue:3

    Topics: Biological Availability; Butyric Acid; Digestion; Diglycerides; Drug Compounding; Glycerol; Glyceryl Ethers; Humans; Hydrolysis; In Vitro Techniques; Intestinal Mucosa; Models, Biological; Pharmaceutical Vehicles; Triglycerides

2011
The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway.
    Carcinogenesis, 2013, Volume: 34, Issue:8

    Topics: Acetylation; Animals; Apoptosis; Butyric Acid; Carcinogenesis; Hepatocytes; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Liver Neoplasms, Experimental; Lysine; Male; Precancerous Conditions; Prodrugs; Random Allocation; Rats; Rats, Wistar; Signal Transduction; Triglycerides; Tumor Suppressor Protein p53; Up-Regulation

2013
The chemopreventive activity of butyrate-containing structured lipids in experimental rat hepatocarcinogenesis.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Butyric Acid; Gene Expression Regulation; Histones; Linseed Oil; Lipids; Liver Neoplasms, Experimental; Male; Oncogenes; Precancerous Conditions; Rats, Wistar; Triglycerides

2016
Volatile Retention and Morphological Properties of Microencapsulated Tributyrin Varied by Wall Material and Drying Method.
    Journal of food science, 2016, Volume: 81, Issue:3

    Topics: Butyric Acid; Capsules; Desiccation; Drug Compounding; Functional Food; gamma-Cyclodextrins; Humans; Intestinal Diseases; Inulin; Soybean Proteins; Triglycerides; Whey Proteins

2016
Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein.
    Oncotarget, 2016, Apr-26, Volume: 7, Issue:17

    Topics: Animals; Apoptosis; Butyric Acid; Carcinoma, Hepatocellular; Cell Compartmentation; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Models, Animal; Exportin 1 Protein; Gene Expression Regulation, Neoplastic; Humans; Karyopherins; Liver Neoplasms; Male; Protein Binding; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Triglycerides; Tumor Suppressor Protein p53

2016
In Vitro Digestion and Fermentation of Microencapsulated Tributyrin for the Delivery of Butyrate.
    Journal of food science, 2017, Volume: 82, Issue:6

    Topics: Butyric Acid; Capsules; Digestion; Drug Delivery Systems; Fermentation; Humans; Triglycerides

2017
Butyrate presence in distinct gastrointestinal tract segments modifies differentially digestive processes and amino acid bioavailability in young broiler chickens.
    Poultry science, 2018, Jan-01, Volume: 97, Issue:1

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Biological Availability; Butyric Acid; Chickens; Diet; Dietary Supplements; Digestion; Gastrointestinal Tract; Male; Triglycerides

2018
Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth.
    Cell host & microbe, 2018, Jan-10, Volume: 23, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Butyric Acid; Clostridium; Dysbiosis; Female; Fermentation; Gastroenteritis; Gastrointestinal Microbiome; Intestinal Mucosa; L-Lactate Dehydrogenase; Lactic Acid; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Salmonella Infections; Salmonella typhimurium; Triglycerides

2018
Antiangiogenic effects of the chemopreventive agent tributyrin, a butyric acid prodrug, during the promotion phase of hepatocarcinogenesis.
    Carcinogenesis, 2019, 08-22, Volume: 40, Issue:8

    Topics: Actins; Angiogenesis Inhibitors; Animals; Apoptosis; Butyric Acid; Carcinogenesis; Carcinoma, Hepatocellular; Cell Movement; Gene Expression Regulation, Neoplastic; Hepatocytes; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Polysaccharides; Prodrugs; Rats; Triglycerides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2019
Bicontinuous Interfacially Jammed Emulsion Gels (bijels) as Media for Enabling Enzymatic Reactive Separation of a Highly Water Insoluble Substrate.
    Scientific reports, 2019, 04-24, Volume: 9, Issue:1

    Topics: Butyric Acid; Catalysis; Chromatography, High Pressure Liquid; Colloids; Emulsions; Gels; Glycerol; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Lipase; Microscopy, Confocal; Models, Chemical; Molecular Structure; Triglycerides; Water

2019
Butyrate, a metabolite of intestinal bacteria, enhances sleep.
    Scientific reports, 2019, 05-07, Volume: 9, Issue:1

    Topics: Administration, Oral; Animals; Butyrates; Butyric Acid; Gastrointestinal Microbiome; Injections; Mice, Inbred C57BL; Rats, Sprague-Dawley; Sleep; Triglycerides

2019
Effects of interesterified lipid design on the short/medium chain fatty acid hydrolysis rate and extent (in vitro).
    Food & function, 2019, Jul-17, Volume: 10, Issue:7

    Topics: Animals; Butyric Acid; Digestion; Fatty Acids; Fatty Acids, Volatile; Gastrointestinal Tract; Hydrolysis; Lipid Metabolism; Lipids; Lipolysis; Particle Size; Rabbits; Stomach; Triglycerides

2019
Butyric Acid Precursor Tributyrin Modulates Hippocampal Synaptic Plasticity and Prevents Spatial Memory Deficits: Role of PPARγ and AMPK.
    The international journal of neuropsychopharmacology, 2022, 06-21, Volume: 25, Issue:6

    Topics: AMP-Activated Protein Kinases; Animals; Butyric Acid; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuronal Plasticity; PPAR gamma; Receptors, N-Methyl-D-Aspartate; Scopolamine Derivatives; Spatial Memory; Triglycerides

2022
Tributyrin alleviates gut microbiota dysbiosis to repair intestinal damage in antibiotic-treated mice.
    PloS one, 2023, Volume: 18, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Butyric Acid; Ceftriaxone; Dysbiosis; Fatty Acids, Volatile; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S; Saline Solution

2023