Page last updated: 2024-08-24

triazoles and valproic acid

triazoles has been researched along with valproic acid in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (18.52)18.2507
2000's5 (18.52)29.6817
2010's12 (44.44)24.3611
2020's5 (18.52)2.80

Authors

AuthorsStudies
Hulsman, JA; Rentmeester, TW1
Pollack, MH; Worthington, JJ1
Chaney, SF; Hurst, G; Kane, JM; Kehne, JH; McCloskey, TC; Petty, MA; Senyah, Y; White, HS; Wolf, HH; Zobrist, R1
Blanc, PD; Brazelton, T; Olson, KR1
Abbott, FS; Chang, TK; Chen, J; Tong, V1
Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N1
Hobara, N; Hokama, N; Kameya, H; Ohshiro, S; Sakanashi, M1
Franklin, MR; Kupferberg, HJ; Schmutz, M; Stables, JP; White, HS; Wolf, HH1
Koide, H; Kusakawa, S; Miyamoto, Y; Mizutani, R; Nakamura, K; Sanbe, A; Tanoue, A; Torii, T; Yamauchi, J1
Balestri, A; Capovilla, G; Coppola, G; Curatolo, P; Fels, A; Franzoni, E; Grosso, S; Habetswallner, F; Mangano, S; Parisi, P; Pascotto, A; Spalice, A; Veggiotti, P; Verrotti, A; Zamponi, N1
Boor, R; Brandt, C; Jürgens, U; Korn-Merker, E; May, TW; Rambeck, B1
Carlson, JE; Critchley, DJ; Lai, WG; Narurkar, M; Williams, ET; Wong, YN; Yoshimura, T1
Claessen, SM; de Jong, E; Kleinjans, JC; Pennings, JL; Piersma, AH; Robinson, JF; Theunissen, PT1
Abbott, FS; Chang, TK; Surendradoss, J1
Dahlin, MG; Ohman, I1
Cavallin, F; Facco, E; Fauci, AJ; Liguori, A; Petti, F; Zanette, G1
Ito, S; Oguni, H1
Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T1
Awaya, T; Heike, T; Ide, M; Kato, T; Nakata, M; Saito, K; Yoshida, T1
Aydın, A; Aydınlı, N; Bektaş, G; Çalışkan, M; Özmen, M; Pembegül Yıldız, E; Tatlı, B1
Connor, DF; Prieto, DI; Zehgeer, AA1
Caraballo, RH; Espeche, A; Fasulo, L; Galichio, S; Pociecha, J; Reyes, G; Semprino, M1
Emnéus, JK; Holst, B; Lauschke, K; Meiser, I; Neubauer, JC; Rasmussen, MA; Rosenmai, AK; Schmidt, K; Taxvig, C; Vinggaard, AM1
Drabik, M; Florek-Łuszczki, M; Głuszak, M; Jankiewicz, M; Kozińska, J; Plech, T; Plewa, Z; Wróblewska-Łuczka, P; Łuszczki, JJ1
García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V1
Fragki, S; Hoogenveen, R; Piersma, AH; Schwillens, P; van Oostrom, C; Zeilmaker, MJ1

Reviews

2 review(s) available for triazoles and valproic acid

ArticleYear
[Treatment of pediatric epilepsy].
    Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:5

    Topics: Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Substitution; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Patient Education as Topic; Piracetam; Practice Guidelines as Topic; Topiramate; Triazines; Triazoles; Valproic Acid

2014
Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.
    Revista de neurologia, 2021, 09-10, Volume: 73, Issue:S01

    Topics: Anticonvulsants; Cannabidiol; Clobazam; Clonazepam; Diazepam; Dioxolanes; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Lennox Gastaut Syndrome; Phenobarbital; Practice Guidelines as Topic; Pyrrolidinones; Spain; Triazoles; Valproic Acid

2021

Trials

2 trial(s) available for triazoles and valproic acid

ArticleYear
Rufinamide in children and adults with Lennox-Gastaut syndrome: first Italian multicenter experience.
    Seizure, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Italy; Lennox Gastaut Syndrome; Male; Spasms, Infantile; Treatment Outcome; Triazoles; Valproic Acid; Young Adult

2010
Acupuncture versus valproic acid in the prophylaxis of migraine without aura: a prospective controlled study.
    Minerva anestesiologica, 2013, Volume: 79, Issue:6

    Topics: Acupuncture Therapy; Adult; Anticonvulsants; Female; Humans; Male; Migraine without Aura; Pain Measurement; Prospective Studies; Sample Size; Serotonin Agents; Triazoles; Tryptamines; Valproic Acid

2013

Other Studies

23 other study(ies) available for triazoles and valproic acid

ArticleYear
Loreclezole monotherapy in patients with partial seizures.
    Epilepsy research, 1992, Volume: 11, Issue:2

    Topics: Anticonvulsants; Epilepsies, Partial; Female; Humans; Male; Substance Withdrawal Syndrome; Triazoles; Valproic Acid

1992
Treatment of dysphoric mania with nefazodone.
    The American journal of psychiatry, 1996, Volume: 153, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Piperazines; Treatment Outcome; Triazoles; Valproic Acid

1996
Preclinical characterization of MDL 27,192 as a potential broad spectrum anticonvulsant agent with neuroprotective properties.
    Epilepsy research, 1997, Volume: 27, Issue:1

    Topics: Animals; Anticonvulsants; Cerebral Infarction; Craniocerebral Trauma; Electroshock; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Kindling, Neurologic; Male; Mice; Mice, Inbred DBA; Motor Activity; Neuroprotective Agents; Rats; Rats, Inbred F344; Rats, Inbred SHR; Rats, Sprague-Dawley; Seizures; Triazoles; Valproic Acid

1997
Toxic effects of nefazodone.
    Annals of emergency medicine, 1997, Volume: 30, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar Disorder; Female; Humans; Neuroleptic Malignant Syndrome; Piperazines; Serotonin; Triazoles; Valproic Acid

1997
New "triptans" and other drugs for migraine.
    The Medical letter on drugs and therapeutics, 1998, Oct-09, Volume: 40, Issue:1037

    Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents

1998
The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats.
    Free radical biology & medicine, 2003, Jun-01, Volume: 34, Issue:11

    Topics: Animals; Anticonvulsants; Biotransformation; Cytochrome P-450 Enzyme System; Dinoprost; Enzyme Inhibitors; F2-Isoprostanes; Gas Chromatography-Mass Spectrometry; Lipid Peroxides; Liver; Male; Oxidative Stress; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Triazoles; Valproic Acid

2003
Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis.
    Epilepsy & behavior : E&B, 2005, Volume: 7, Issue:4

    Topics: Animals; Anticonvulsants; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Kindling, Neurologic; Linear Models; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Triazoles; Valproic Acid

2005
Investigation of low levels of plasma valproic acid concentration following simultaneous administration of sodium valproate and rizatriptan benzoate.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:3

    Topics: Animals; Anticonvulsants; Drug Interactions; Male; Monocarboxylic Acid Transporters; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Triazoles; Tryptamines; Valproic Acid

2007
The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.
    Epilepsia, 2008, Volume: 49, Issue:7

    Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Injections, Intraperitoneal; Mice; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Severity of Illness Index; Triazoles; Valproic Acid

2008
Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells.
    Experimental cell research, 2009, Jul-15, Volume: 315, Issue:12

    Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Anticonvulsants; Cell Line; Cell Line, Tumor; GTPase-Activating Proteins; Mice; Neurites; Neurogenesis; Triazoles; Up-Regulation; Valproic Acid

2009
Serum concentrations of rufinamide in children and adults with epilepsy: the influence of dose, age, and comedication.
    Therapeutic drug monitoring, 2011, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Male; Middle Aged; Seizures; Spasms, Infantile; Triazoles; Valproic Acid; Young Adult

2011
Investigation of the metabolism of rufinamide and its interaction with valproate.
    Drug metabolism letters, 2011, Volume: 5, Issue:4

    Topics: Acyl Coenzyme A; Anticonvulsants; Biotransformation; Butyrates; Carboxylesterase; Cytosol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; Hydrolysis; Intestines; Liver; Microsomes, Liver; Triazoles; Valproic Acid

2011
Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn).
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 125, Issue:2

    Topics: Animal Testing Alternatives; Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Embryonic Stem Cells; Gene Expression Profiling; Gene Expression Regulation, Developmental; Mice; Neural Crest; Neurites; Neurogenesis; Time Factors; Toxicity Tests; Triazoles; Valproic Acid

2012
Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes.
    Toxicology and applied pharmacology, 2012, Nov-01, Volume: 264, Issue:3

    Topics: Animals; Cell Culture Techniques; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Hepatocytes; Male; Molecular Structure; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles; Valproic Acid

2012
Rufinamide in children with refractory epilepsy: pharmacokinetics, efficacy, and safety.
    Neuropediatrics, 2012, Volume: 43, Issue:5

    Topics: Adolescent; Analysis of Variance; Anticonvulsants; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Male; Retrospective Studies; Triazoles; Valproic Acid

2012
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine

2014
A granulocytosis associated with rufinamide: A case report.
    Brain & development, 2015, Volume: 37, Issue:8

    Topics: Agranulocytosis; Anticonvulsants; Child; Clonazepam; Epilepsy; Humans; Male; Triazoles; Valproic Acid

2015
Aggravation of atonic seizures by rufinamide: A case report.
    Brain & development, 2016, Volume: 38, Issue:7

    Topics: Anticonvulsants; Benzodiazepines; Brain; Child; Clobazam; Drug Resistant Epilepsy; Drug Therapy, Combination; Electroencephalography; Humans; Levetiracetam; Male; Piracetam; Seizures; Triazoles; Valproic Acid

2016
Use of Suvorexant for Sleep Regulation in an Adolescent with Early-Onset Bipolar Disorder.
    Journal of child and adolescent psychopharmacology, 2019, Volume: 29, Issue:5

    Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Azepines; Bipolar Disorder; Humans; Lurasidone Hydrochloride; Male; Sleep Aids, Pharmaceutical; Sleep Initiation and Maintenance Disorders; Triazoles; Valproic Acid

2019
Rufinamide as add-on therapy in children with epileptic encephalopathies other than Lennox-Gastaut syndrome: A study of 34 patients.
    Epilepsy & behavior : E&B, 2020, Volume: 108

    Topics: Adolescent; Anticonvulsants; Argentina; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Lennox Gastaut Syndrome; Male; Retrospective Studies; Seizures; Triazoles; Valproic Acid

2020
A novel human pluripotent stem cell-based assay to predict developmental toxicity.
    Archives of toxicology, 2020, Volume: 94, Issue:11

    Topics: Biological Assay; Cell Line; Developmental Biology; Embryoid Bodies; Epoxy Compounds; Female; Humans; Male; Myocytes, Cardiac; Oxazines; Pluripotent Stem Cells; Teratogenesis; Teratogens; Thalidomide; Toxicity Tests; Triazoles; Valproic Acid; Xanthenes

2020
Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice.
    Neurochemical research, 2021, Volume: 46, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Male; Mice; Muscle Strength; Phenobarbital; Phenytoin; Rotarod Performance Test; Seizures; Thiones; Triazoles; Valproic Acid

2021
Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach.
    Toxicology, 2022, 01-15, Volume: 465

    Topics: Animals; Biological Transport; Biomarkers; Caproates; Cell Line; Dose-Response Relationship, Drug; Female; Fetal Blood; Gestational Age; Glycolates; Humans; Maternal-Fetal Exchange; Miconazole; Models, Biological; Permeability; Phthalic Acids; Pregnancy; Proof of Concept Study; Rats; Reproducibility of Results; Risk Assessment; Silanes; Toxicity Tests; Toxicokinetics; Triazoles; Trophoblasts; Valproic Acid

2022