Compounds > triazoles
Page last updated: 2024-08-24

triazoles and transforming growth factor beta

triazoles has been researched along with transforming growth factor beta in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (17.24)18.2507
2000's2 (6.90)29.6817
2010's17 (58.62)24.3611
2020's5 (17.24)2.80

Authors

AuthorsStudies
Shankar, G; Stern, PH1
Ishidoya, S; Klahr, S; Morrissey, J1
Ishidoya, S; Klahr, S; McCracken, R; Morrissey, J; Reyes, A1
Alessandro, R; Jacobs, W; Kim, YS; Kohn, EC; Liotta, LA; Stetler-Stevenson, WG1
Parent, JL; Stankova, J1
Kim, DK; Kim, J; Park, HJ1
Andrisani, OM; Bilodeau, ML; Ji, M; Paris, M1
Fabregat, I; Sancho, P1
Flynn, ER; Manigrasso, MB; Marbury, DC; Maric, C; Sawyer, RT1
Camacho, A; de los Santos, I; Di Lello, F; Gómez-Mateos, J; Macías, J; Márquez, M; Mata, R; Ojeda, G; Pineda, JA; Portilla, J; Rivero, A; Sanz-Sanz, J; Viloria, MM1
Cicero, G; Gorska, M; Knap, N; Kuban-Jankowska, A; Popowska, U; Sawczuk, W; Sielicka-Dudzin, A; Wozniak, F1
Alattar, M; Li, WP; Linder, G; Malek, R; Price, JD; Rother, KI; Tarbell, KV; Zimmermann, B1
Aebli, N; Baur, M; Bertolo, A; Ferguson, SJ; Stoyanov, J1
Beyer, C; Dees, C; Distler, A; Distler, JH; Distler, O; Kreuter, A; Lin, NY; Palumbo, K; Schett, G; Susok, L; Zerr, P; Zhang, Y1
Kim, JS; Kim, MJ; Lim, W; Nam, JS; Park, SA; Park, SY; Yhong Sheen, Y1
Bae, E; Gu, YK; Hirao, A; Ishihara, K; Jeong, ES; Jin, CH; Jomen, Y; Kim, DH; Kim, DK; Kim, DW; Kim, SJ; Krause, DS; Li, S; Naka, K; Ooshima, A; Oshima, H; Oshima, M; Sheen, YY; Takihara, Y1
Calvo, F; Chakravarty, P; Del Pozo Martin, Y; Derzsi, S; Hill, CS; Malanchi, I; Ombrato, L; Park, D; Ramachandran, A; Sahai, E; Spencer-Dene, B1
Chang, H; Du, S; Liu, H; Liu, Y; Wang, P; Xue, M; Zhang, L1
Baldassarre, M; Bates, JG; Breckenridge, DG; Calderwood, DA; Chen, F; Kuruvilla, L; Martinez, R; Mihaylova, VT; Schlessinger, J; Shi, X; Sperandio, D; Turk, BE; Viviano, S; Yue, P1
Aoki, T; Fujiwara, H; Fukayama, M; Hasegawa, K; Hoshikawa, M; Ijichi, H; Isayama, H; Koike, K; Kokudo, N; Kudo, Y; Miyabayashi, K; Morishita, Y; Nakai, Y; Nakatsuka, T; Sakamoto, Y; Takahashi, R; Tanaka, M; Tanaka, Y; Tateishi, K; Yamamoto, K1
Kong, X; Liu, X; Ma, J; Ou, C; Wang, Q; Yu, Y; Zhang, Y1
Anand, P; Bradner, JE; Brown, JD; Duan, Q; Haldar, SM; Huang, Y; Lemieux, ME; McKinsey, TA; McMahon, S; Sahadevan, A; Salunga, HT; Shah, H; Srivastava, D; Thomas, S; Zhang, R1
Huang, A; Li, Z; Lin, Z; Ma, H; Mei, H; Shi, L; Wang, J; Wang, Y; Wu, G; Zhang, T; Zhou, F1
Afshari, AR; Arjmand, MH; Asgharzadeh, F; Avan, A; Binabaj, MM; Fakhraei, M; Ferns, GA; Hassanian, SM; Khazaei, M; Mehraban, S; Naghinezhad, J; Parizadeh, MR; Rahmani, F; Ryzhikov, M; Sayyed-Hosseinian, SH; Soleimani, A1
Alexanian, M; Bagchi, RA; Cavasin, MA; Enyart, BY; Felisbino, MB; Haldar, SM; Hirsch, RA; Koch, KA; Lam, MPY; Lemieux, ME; Lin, CY; McKinsey, TA; Qi, J; Riching, AS; Smith, HE; Song, K; Srivastava, D; Stratton, MS1
An, H; Heo, JS; Hong, CP; Hong, E; Kang, JM; Kim, SJ; Lee, S; Ooshima, A; Park, J; Park, JO; Park, S; Park, SH1
Ferrão, PM; Garzoni, LR; Meuser-Batista, M; Moreira, OC; Nisimura, LM; Nogueira, ADR; Urbina, JA; Waghabi, MC1
Cho, I; Choi, J; Park, J; Sheen, Y1
Cho, I; Choi, J; Park, J; Sheen, YY1

Reviews

2 review(s) available for triazoles and transforming growth factor beta

ArticleYear
Role of angiotensin II in the tubulointerstitial fibrosis of obstructive nephropathy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1995, Volume: 26, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Collagen; Enalapril; Extracellular Matrix Proteins; Fibrosis; Kidney; Kidney Diseases; Kidney Tubules; Macrophages; Monocytes; Rats; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Triazoles; Ureteral Obstruction

1995
Geldanamycin and its derivatives as Hsp90 inhibitors.
    Frontiers in bioscience (Landmark edition), 2012, 06-01, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Cyclin-Dependent Kinases; HSP90 Heat-Shock Proteins; Humans; Indoles; Lactams, Macrocyclic; Macrolides; Models, Biological; Mutation; Novobiocin; Proto-Oncogene Proteins c-raf; src-Family Kinases; Transforming Growth Factor beta; Triazoles; Tumor Suppressor Protein p53

2012

Trials

1 trial(s) available for triazoles and transforming growth factor beta

ArticleYear
Effects of short-term sitagliptin treatment on immune parameters in healthy individuals, a randomized placebo-controlled study.
    Clinical and experimental immunology, 2013, Volume: 174, Issue:1

    Topics: Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Down-Regulation; Glucagon-Like Peptide 1; Humans; Immunomodulation; Outcome Assessment, Health Care; Pyrazines; Sitagliptin Phosphate; T-Lymphocyte Subsets; Time Factors; Transforming Growth Factor beta; Triazoles; Up-Regulation

2013

Other Studies

26 other study(ies) available for triazoles and transforming growth factor beta

ArticleYear
Interactions of tumor necrosis factor with local and systemic factors in fetal rat limb bones.
    Calcified tissue international, 1992, Volume: 51, Issue:5

    Topics: Animals; Azepines; Bone and Bones; Bone Resorption; Culture Techniques; Dexamethasone; Hindlimb; Indomethacin; Interferon-gamma; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Parathyroid Hormone; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sialoglycoproteins; Transforming Growth Factor beta; Triazoles; Tumor Necrosis Factor-alpha

1992
Angiotensin II receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral obstruction.
    Kidney international, 1995, Volume: 47, Issue:5

    Topics: Actins; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Collagen; Disease Models, Animal; Enalapril; Female; Immunohistochemistry; Monocytes; Nephritis, Interstitial; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Triazoles; Ureteral Obstruction

1995
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).
    The Journal of biological chemistry, 1994, Aug-26, Volume: 269, Issue:34

    Topics: Biological Transport; Blotting, Northern; Calcium; Dose-Response Relationship, Drug; Enzyme Induction; Gelatin; Gelatinases; Humans; Imidazoles; Matrix Metalloproteinase 2; Metalloendopeptidases; RNA, Messenger; Structure-Activity Relationship; Transforming Growth Factor beta; Triazoles; Tumor Cells, Cultured

1994
Transforming growth factor-beta up-regulates the gene expression of the human platelet-activating factor receptor in monocytic and B cell lines.
    Biochemical and biophysical research communications, 1993, Dec-30, Volume: 197, Issue:3

    Topics: Azepines; B-Lymphocytes; Calcium; Cell Line; Cycloheximide; Dactinomycin; Gene Expression; Humans; Ionomycin; Kinetics; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Triazoles; Tumor Cells, Cultured; Up-Regulation

1993
Synthesis and biological evaluation of novel 2-pyridinyl-[1,2,3]triazoles as inhibitors of transforming growth factor beta 1 type 1 receptor.
    Bioorganic & medicinal chemistry letters, 2004, May-17, Volume: 14, Issue:10

    Topics: Activin Receptors, Type I; Binding Sites; Cell Line, Tumor; Dose-Response Relationship, Drug; Fibrosis; Genes, Reporter; Humans; Luciferases; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Structure-Activity Relationship; Transcription, Genetic; Transfection; Transforming Growth Factor beta; Triazoles

2004
Adenosine signaling promotes neuronal, catecholaminergic differentiation of primary neural crest cells and CNS-derived CAD cells.
    Molecular and cellular neurosciences, 2005, Volume: 29, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine-5'-(N-ethylcarboxamide); Adrenal Medulla; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Catecholamines; Cell Differentiation; Cell Line; Cells, Cultured; Chromaffin Cells; Coturnix; Culture Media, Serum-Free; Cyclic AMP; Neural Crest; Neurons; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Signal Transduction; Sympathetic Nervous System; Transforming Growth Factor beta; Triazoles; Tyrosine 3-Monooxygenase

2005
The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells.
    Biochemical pharmacology, 2011, Apr-01, Volume: 81, Issue:7

    Topics: Animals; Apoptosis; Base Sequence; Benzoxazoles; Blotting, Western; Cell Division; Cell Line, Tumor; DNA Primers; Enzyme Inhibitors; Humans; Liver Neoplasms; NADPH Oxidases; Rats; Signal Transduction; Transforming Growth Factor beta; Triazoles

2011
Inhibition of estradiol synthesis attenuates renal injury in male streptozotocin-induced diabetic rats.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:3

    Topics: Acute Kidney Injury; Albuminuria; Anastrozole; Animals; Aromatase Inhibitors; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Estradiol; Interleukin-6; Male; Nitriles; Rats; Rats, Sprague-Dawley; Streptozocin; Testosterone; Transforming Growth Factor beta; Triazoles

2011
Lack of short-term increase in serum mediators of fibrogenesis and in non-invasive markers of liver fibrosis in HIV/hepatitis C virus-coinfected patients starting maraviroc-based antiretroviral therapy.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012, Volume: 31, Issue:8

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biomarkers; Cyclohexanes; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Liver Cirrhosis; Male; Maraviroc; Matrix Metalloproteinase 2; Middle Aged; Pilot Projects; Prospective Studies; RNA, Viral; Serum; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Triazoles

2012
Physiological testosterone levels enhance chondrogenic extracellular matrix synthesis by male intervertebral disc cells in vitro, but not by mesenchymal stem cells.
    The spine journal : official journal of the North American Spine Society, 2014, Mar-01, Volume: 14, Issue:3

    Topics: Adult; Aggrecans; Anastrozole; Aromatase Inhibitors; Cell Differentiation; Cell Survival; Cells, Cultured; Chondrogenesis; Collagen Type II; Extracellular Matrix; Female; Humans; In Vitro Techniques; Intervertebral Disc; Male; Mesenchymal Stem Cells; Middle Aged; Nitriles; Sex Factors; Testosterone; Transforming Growth Factor beta; Triazoles

2014
Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
    Annals of the rheumatic diseases, 2015, Volume: 74, Issue:5

    Topics: Adult; Aged; Animals; Casein Kinase II; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Humans; Janus Kinase 2; Male; Mice; Middle Aged; Scleroderma, Systemic; Signal Transduction; Skin; STAT3 Transcription Factor; Transforming Growth Factor beta; Triazoles; Young Adult

2015
TIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling.
    Scientific reports, 2015, Nov-09, Volume: 5

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Communication; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Disease Progression; Epithelial-Mesenchymal Transition; Female; Focal Adhesion Protein-Tyrosine Kinases; Hepatic Stellate Cells; Heterografts; Humans; Liver Neoplasms; Mice; Proto-Oncogene Proteins c-akt; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Triazoles

2015
Novel oral transforming growth factor-β signaling inhibitor EW-7197 eradicates CML-initiating cells.
    Cancer science, 2016, Volume: 107, Issue:2

    Topics: Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Disease Models, Animal; Humans; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridazines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transfection; Transforming Growth Factor beta; Triazoles

2016
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization.
    Cell reports, 2015, Dec-22, Volume: 13, Issue:11

    Topics: Animals; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Breast Neoplasms; CD24 Antigen; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Homeodomain Proteins; Humans; Lung Neoplasms; Mice; Mice, Nude; Mice, Transgenic; Neoplasm Metastasis; Neoplastic Stem Cells; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA Interference; Signal Transduction; Smad Proteins; Thrombospondins; Transforming Growth Factor beta; Transplantation, Heterologous; Triazoles

2015
Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition.
    Nucleic acids research, 2016, Apr-07, Volume: 44, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Epithelial Cells; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 4; Histones; Humans; Lung Neoplasms; Nuclear Proteins; Phenotype; Proto-Oncogene Protein c-ets-2; RNA, Small Interfering; Sequence Analysis, RNA; Signal Transduction; Smad3 Protein; Survival Analysis; Transcription Factors; Transcriptome; Transforming Growth Factor beta; Triazoles

2016
Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 08-02, Volume: 113, Issue:31

    Topics: Azepines; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; Humans; Molecular Structure; Proteins; Proto-Oncogene Proteins c-myc; Receptors, Transforming Growth Factor beta; RNA Interference; Signal Transduction; Transcription Factors; Transforming Growth Factor beta; Triazoles

2016
Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Actins; Animals; Azepines; Cancer-Associated Fibroblasts; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Cytokines; Disease Progression; Epigenesis, Genetic; Hedgehog Proteins; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred NOD; Mice, SCID; Pancreas; Pancreatic Neoplasms; Primary Cell Culture; Proteins; Signal Transduction; STAT3 Transcription Factor; Transcription, Genetic; Transforming Growth Factor beta; Triazoles; Xenograft Model Antitumor Assays

2016
Chemokine receptor CCR5 and CXCR4 might influence virus replication during IBDV infection.
    Microbial pathogenesis, 2017, Volume: 107

    Topics: Animals; Benzylamines; Bursa of Fabricius; CCR5 Receptor Antagonists; Cell Movement; Chickens; Cyclams; Cyclohexanes; Cytokines; Heterocyclic Compounds; Infectious bursal disease virus; Interferon-gamma; Interleukin-2; Interleukin-6; Interleukin-8; Maraviroc; Poultry Diseases; Real-Time Polymerase Chain Reaction; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; RNA, Messenger; T-Lymphocytes; Transcription, Genetic; Transforming Growth Factor beta; Triazoles; Viral Structural Proteins; Virus Replication

2017
BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure.
    Science translational medicine, 2017, 05-17, Volume: 9, Issue:390

    Topics: Animals; Azepines; Cardiomegaly; Gene Regulatory Networks; Heart Failure; Humans; Induced Pluripotent Stem Cells; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NF-kappa B; Proteins; Signal Transduction; Transforming Growth Factor beta; Triazoles

2017
Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis.
    Scientific reports, 2018, 01-17, Volume: 8, Issue:1

    Topics: Animals; Azepines; Cell Line, Tumor; Cell Proliferation; Collagen Type I; Female; Fibroblasts; Gamma Rays; Gene Expression Regulation; Humans; Hydroxyproline; Lung; MCF-7 Cells; Molecular Targeted Therapy; NF-kappa B; Nuclear Proteins; Proteins; Proto-Oncogene Proteins c-myc; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Smad2 Protein; Smad3 Protein; Transcription Factors; Transforming Growth Factor beta; Triazoles

2018
Novel oral transforming growth factor-β signaling inhibitor potently inhibits postsurgical adhesion band formation.
    Journal of cellular physiology, 2020, Volume: 235, Issue:2

    Topics: 3T3 Cells; Aniline Compounds; Animals; Apoptosis; Fibroblasts; Gene Expression Regulation; Inflammation; Mice; Oxidative Stress; Random Allocation; Tissue Adhesions; Transforming Growth Factor beta; Triazoles

2020
Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.
    Circulation research, 2019, 09-13, Volume: 125, Issue:7

    Topics: Animals; Azepines; Cell Adhesion Molecules; Cells, Cultured; Chromatin; Enhancer Elements, Genetic; Epigenesis, Genetic; Extracellular Matrix; Female; Fibrosis; Heart Failure; Heart Ventricles; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Myofibroblasts; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Protein Binding; Rats; Rats, Sprague-Dawley; RNA Polymerase II; Transcription Factors; Transcriptome; Transforming Growth Factor beta; Triazoles

2019
Inhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models.
    Scientific reports, 2020, 02-19, Volume: 10, Issue:1

    Topics: Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Drug Synergism; Epithelial-Mesenchymal Transition; Fluorouracil; Gene Expression Regulation, Neoplastic; Irinotecan; Leucovorin; Liposomes; Mice, Inbred C57BL; Nanoparticles; Neoplasm Invasiveness; Pancreatic Neoplasms; Signal Transduction; Survival Analysis; Transcriptome; Transforming Growth Factor beta; Triazoles; Tumor Stem Cell Assay; Up-Regulation

2020
Effect of Posaconazole in an in vitro model of cardiac fibrosis induced by Trypanosoma cruzi.
    Molecular and biochemical parasitology, 2020, Volume: 238

    Topics: Animals; Cell Culture Techniques; Chagas Cardiomyopathy; Endomyocardial Fibrosis; Extracellular Matrix Proteins; Fetus; Fibronectins; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Laminin; Mice; Models, Biological; Myocytes, Cardiac; Parasite Load; Primary Cell Culture; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2020
Co-treatment with vactosertib, a novel, orally bioavailable activin receptor-like kinase 5 inhibitor, suppresses radiotherapy-induced epithelial-to-mesenchymal transition, cancer cell stemness, and lung metastasis of breast cancer.
    Radiology and oncology, 2022, 04-07, Volume: 56, Issue:2

    Topics: Aniline Compounds; Animals; Breast Neoplasms; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Humans; Lung Neoplasms; Mice; Protein Kinase Inhibitors; Receptor, Transforming Growth Factor-beta Type I; Transforming Growth Factor beta; Triazoles

2022
Radiotherapy-induced oxidative stress and fibrosis in breast cancer are suppressed by vactosertib, a novel, orally bioavailable TGF-β/ALK5 inhibitor.
    Scientific reports, 2022, 09-27, Volume: 12, Issue:1

    Topics: Aniline Compounds; Animals; Female; Fibrocystic Breast Disease; Fibronectins; Fibrosis; Humans; Mice; Neoplasm Recurrence, Local; NF-E2-Related Factor 2; Oxidative Stress; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Transforming Growth Factor beta; Transforming Growth Factors; Triazoles

2022