Page last updated: 2024-08-24

triazoles and topotecan

triazoles has been researched along with topotecan in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Gupta, A; Mao, Q; Unadkat, JD1
Ashwell, S; Brassil, P; Breed, J; Deng, C; Ezhuthachan, J; Grondine, M; Horn, C; Liu, D; Lyne, P; Newcombe, N; Oza, V; Pass, M; Read, J; Su, M; Toader, D; Yu, D; Yu, Y; Zabludoff, S1
Chen, LK; Chen, WQ; Chen, ZS; Fu, LW; Huang, ZC; Talele, TT; Tang, SJ; To, KK; Wang, F; Wang, XK; Zhang, YK1
Basler, C; Benner, C; Bouvier, N; Bukreyev, A; Campisi, L; Chen, X; Edwards, M; Fenouil, R; GarcĂ­a-Sastre, A; Heinz, S; Ho, JSY; Jin, J; Jordan, S; Lagda, AC; Marazzi, I; Martinez-Gil, L; Merad, M; Metreveli, G; Munoz-Fontela, C; Peralta, Z; Pietzsch, C; Rialdi, A; van Bakel, H; Weirauch, M; Zhao, N1
Bean, S; Carter, BW; Colen, R; Gong, J; Janku, F; Karp, DD; McQuinn, L; Meric-Bernstam, F; Milton, DR; Naing, A; Ogbonna, DC; Pant, S; Piha-Paul, SA; Shah, J; Subbiah, V; Thein, KZ; Tsimberidou, A; Zarifa, A1

Trials

1 trial(s) available for triazoles and topotecan

ArticleYear
Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study.
    Investigational new drugs, 2021, Volume: 39, Issue:5

    Topics: Active Transport, Cell Nucleus; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Exportin 1 Protein; Female; Humans; Hydrazines; Karyopherins; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Receptors, Cytoplasmic and Nuclear; Topotecan; Triazoles

2021

Other Studies

4 other study(ies) available for triazoles and topotecan

ArticleYear
Interactions of azole antifungal agents with the human breast cancer resistance protein (BCRP).
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:12

    Topics: Antifungal Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Survival; Chlorophyll; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Flow Cytometry; Fluconazole; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Itraconazole; Ketoconazole; Neoplasm Proteins; Pyrimidines; Topotecan; Transfection; Triazoles; Voriconazole

2007
Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2012, Mar-15, Volume: 22, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Checkpoint Kinase 1; Colonic Neoplasms; Combined Modality Therapy; Crystallography, X-Ray; DNA Damage; Dose-Response Relationship, Drug; Humans; Mice; Mice, Nude; Models, Molecular; Protein Conformation; Protein Kinase Inhibitors; Protein Kinases; Structure-Activity Relationship; Topotecan; Triazoles; Xenograft Model Antitumor Assays

2012
CEP-33779 antagonizes ATP-binding cassette subfamily B member 1 mediated multidrug resistance by inhibiting its transport function.
    Biochemical pharmacology, 2014, Sep-15, Volume: 91, Issue:2

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Heterografts; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Pyridines; Real-Time Polymerase Chain Reaction; Rhodamine 123; Topotecan; Triazoles

2014
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.
    Science (New York, N.Y.), 2016, May-27, Volume: 352, Issue:6289

    Topics: Animals; Azepines; Camptothecin; DNA Topoisomerases, Type I; Ebolavirus; Flavonoids; Gene Expression Regulation; HEK293 Cells; Hemorrhagic Fever, Ebola; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Influenza A virus; Interferon-beta; Mice; Mice, Inbred C57BL; Piperidines; Positive Transcriptional Elongation Factor B; RNA Polymerase II; Sendai virus; Staphylococcal Infections; Staphylococcus aureus; Topoisomerase I Inhibitors; Topotecan; Transcription, Genetic; Triazoles

2016