Page last updated: 2024-08-24

triazoles and thiophenes

triazoles has been researched along with thiophenes in 113 studies

Research

Studies (113)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (7.08)	18.7374
1990's	8 (7.08)	18.2507
2000's	16 (14.16)	29.6817
2010's	75 (66.37)	24.3611
2020's	6 (5.31)	2.80

Authors

Authors	Studies
Kilbey, BJ; Zetterberg, LG	1
Aboul Wafa, OM; Berto, FA	1
Atienza, J; Claramunt, RM; Elguero, J; Escario, JA; Gómez Barrio, A; Mester, B	1
Crowley, H; Flynn, T; Maresca, C; Mason, C; O'Donnell, M; Walser, A; Yaremko, B	1
Crowley, H; Flynn, T; Maresca, C; Mason, C; O'Donnell, M; Walser, A	1
Baumann, K; Binder, D; Noe, CR; Wildburger, JM	1
Maruyama, Y; Mikashima, H; Tahara, T; Terasawa, M	1
Glukhov, NV; Kulikova, LK	1
Berk, S; Gisser, H	1
Theus, PM; Tiedt, H; Weuffen, W	1
Dunoff, RY; Graboyes, H; Jaffe, G; Karash, CB; Pachter, IJ; Snader, K; Weinstock, J	1
Modica, M; Russo, F; Santagati, A; Santagati, M; Spampinato, S	1
Kuwano, M; Ono, M	1
Algueró, M; Bartroli, J; Boncompte, E; Conte, L; Forn, J; García-Rafanell, J; Merlos, M; Ramis, J; Turmo, E; Vericat, ML	1
Bu, W; Li, XM; Qin, LX; Tang, ZY; Xia, JL	1
Dalvie, DK; Kalgutkar, AS; Khojasteh-Bakht, SC; O'Donnell, JP; Obach, RS	1
Henry, AA; Matsuda, S; Romesberg, FE; Schultz, PG	1
KANNER, LC; KOZLOFF, LM	1
Dobosz, M; Kosikowska, U; Malm, A; Pitucha, M; Wujec, M	1
Almási, J; Rihmer, Z	1
Berrino, L; de Novellis, V; Maione, S; Marabese, I; Mariani, L; Oliva, P; Palazzo, E; Rossi, F; Scafuro, M; Siniscalco, D	1
Aoudjit, L; Potapov, A; Takano, T	1
Ammar, H; Malani, AK	1
Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Mao, LJ; Rennard, SI; Shen, L; Sugiura, H; Togo, S; Wang, XQ	1
Chen, XB; Cherukuri, DP; Goulet, AC; Han, Y; Heimark, RL; Meuillet, E; Nelson, MA; Regan, JW; Young, RN	1
Fisher, PW; Hofmann, GA; Janson, CA; Johnson, RK; Kirkpatrick, RB; Ma, C; Marino, JP; Mattern, M; Meek, TD; Ryan, MD; Schulz, C; Smith, WW; Tew, DG; Thompson, SK; Tomazek, TA; Veber, DF; Xiong, WC; Yamamoto, Y; Yamashita, K; Yang, G	1
Bis, SJ; Bruce, TJ; Cudworth, DP; Dintenfass, LP; Dripps, JE; Gifford, JM; Guenthenspberger, KA; Hamilton, CT; Hegde, VB; Johnson, PL; Karr, LL; Kempe, MK; McCormick, DC; Pechacek, JT; Schoonover, JR; Tisdell, FE; Yap, MC	1
Cicha, MZ; Hökfelt, T; Kopp, UC; Mulder, J; Smith, LA	1
Da Settimo, F; Martini, C; Montali, M; Taliani, S; Trincavelli, ML	1
Al-Bayati, RH; Aouad, M; Rezki, N; Sharba, AH	1
Hussar, DA	2
Barnett, JM; Clark, ML; Penn, JS; Yanni, SE	1
Cuthbert, AW	1
Balan, A; Ekiz, F; Timur, S; Toppare, L; Yuksel, M	1
Berthelette, C; Chateauneuf, A; Li, L; Ouellet, M; Sturino, CF; Wang, Z	1
Dighe, R; Kanase, V; Shiradkar, M; Thomas, J	1
Arun, B; Brown, PH; Castiglione, M; Cuzick, J; DeCensi, A; Dunn, B; Forbes, JF; Glaus, A; Howell, A; Vogel, V; von Minckwitz, G; Zwierzina, H	1
Al-Majid, AM; Alamary, AS; Mabkhot, YN	1
Hinge, VK; Mondal, M; Pathak, RK; Rao, CP	1
Beigelman, L; Blatt, L; Cai, H; Deval, J; Fan, B; Kao, CC; Ranjith-Kumar, CT; Smith, DB; Soulard, C; Yi, G	1
Brooks, W; Daniel, KG; Ge, Y; Guida, WC; Jain, S; Kazi, A; Lawrence, HR; Luo, Y; Marsilio, F; Sebti, SM	1
Fuskevåg, OM; Gogvadze, V; Johnsen, JI; Kock, A; Kogner, P; Kruspig, B; Rasmuson, A; Simón-Santamaría, J; Sveinbjörnsson, B	1
Chen, H; Ma, Z; Wang, N; Yin, Y; Yu, F; Yun, Y	1
Anjana Devi, T; Jain, N; Kalivendi, SV; Kantevari, S; Murthy, R; Patpi, SR; Pulipati, L; Sridhar, B; Sriram, D; Yogeeswari, P	1
Capuano, G; Nicolle, LE; Usiskin, K; Ways, K	1
Kadokura, T; Keirns, J; Krauwinkel, WJ; Smulders, RA; van Dijk, J; Veltkamp, SA; Zhang, W	1
Nyirjesy, P; Usiskin, K; Ways, K; Zhao, Y	1
Burke, M; Cogan, D; Gao, DA; Haverty, K; Heim-Riether, A; Hickey, ER; Moss, N; Nagaraja, R; Netherton, M; O'Shea, K; Ramsden, P; Schwartz, R; Shih, DT; Ward, Y; Xiong, Z; Young, E; Zhang, Q	1
Barrett, DG; Beavers, LS; Briere, DA; Coskun, T; Dubois, SL; Efanov, AM; Franciskovich, JB; Michael, MD; O'Farrell, LS; Syed, SK	1
Appleby, TC; Bidgood, AM; Byun, D; Canales, E; Clarke, MO; Doerffler, E; Eng, S; Fenaux, M; Hashash, A; Krawczyk, SH; Lazerwith, SE; Leavitt, SA; Lee, YJ; Lew, W; Liu, Q; Mabery, EM; Matles, M; Mertzman, M; Morganelli, P; Murray, BP; Mwangi, J; Tian, Y; Watkins, WJ; Xu, L; Ye, H; Zhang, J	1
Ashour, HM; El-Ashmawy, IM; Rizk, OH; Shaaban, OG	1
Abbate, I; Almerico, AM; Dattolo, G; Lauria, A; Martorana, A; Patella, C	1
Li, X; Li, Y; Tan, L; Tang, T; Wang, J; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z	1
Canovatchel, W; Fu, M; Gross, JL; Guarisco, M; Kawaguchi, M; Meininger, G; Rosenstock, J; Schernthaner, G; Yee, J	1
Johnson, MS	1
Hwang, DH; Kang, H; Kang, IN; Kim, B; Kim, BJ; Kim, JH; Kim, JS; Shin, N; Shin, WS; Song, CE; Wood, S	1
Gu, Y; Han, Y; Ma, G; Shi, H; Tang, C; Wang, Q; Yan, G	1
Canovatchel, W; Davidson, J; Januszewicz, A; Lavalle-González, FJ; Meininger, G; Qiu, R; Tong, C	1
Alba, M; Canovatchel, W; Cefalu, WT; Edwards, R; Jodar, E; Kim, KA; Meininger, G; Stenlöf, K; Tong, C	1
Cantonwine, EG; Johnson, RC	1
Baxi, SM; Estrella, H; Li, C; Liu, KK; Mehta, PP; Smeal, T; Walls, M; Yin, MJ; Zhu, J; Zientek, M; Zong, Q	1
Andersson, G; Hu, L; Jacobson, A; Lind, T; Melhus, H; Pejler, G; Sundqvist, A	1
Schnell, O	1
Bailey, RA; Blonde, L; Damaraju, CV; Martin, SC; Meininger, GE; Rupnow, MF	1
Forst, T; Goldenberg, R; Guthrie, R; Meininger, G; Stein, P; Vijapurkar, U; Yee, J	1
Ferrannini, E; Mari, A; Polidori, D	1
Al-Abdullah, ES; Al-Tamimi, AM; Cırak, C; El-Emam, AA; Sert, Y; Ucun, F	1
Guthrie, R; Slee, A; Traina, S	1
Geolchanyan, AV; Musumeci, D; Petrosyan, SG; Roviello, GN; Roviello, V; Saghyan, AS; Simonyan, HM	1
Birinci, E; Burnaz, NA; Çelik, F; Küçük, M; Sancak, K; Soylu, S; Ünver, Y	1
Baltaş, N; Bekircan, O; Kahveci, B; Menteşe, E; Yılmaz, F	1
Lubenov, LA; Mavrova, ATs; Tsenov, JA; Wesselinova, D	1
Douglas, MW; Eltahla, AA; Tay, E; White, PA	1
Dzitko, K; Paneth, A; Paneth, P; Pawełczyk, J; Plech, T; Węglińska, L	1
Bridges, CR; Pollit, AA; Seferos, DS	1
Jin, YH; Jin, Z; Kim, S; Lee, G; Park, CS; Park, YS	1
Gallego, D; Jimenez, M; Mañé, N; Martin, MT; Martinez-Cutillas, M	1
Cai, Y; Libby, P; Rocha, VZ; Shimizu, K; Sukhova, GK; Tang, EH; Vanhoutte, PM; Wong, CK; Xu, A; Xuan, G	1
An, Y; Li, N; Song, Y; Tang, H; Wang, Y; Zhang, L	1
Bailey, RA; Blonde, L; Meininger, GE; Rupnow, MF; Vijapurkar, U	1
Bonewald, L; Brotto, M; Igwe, O; Mo, C; Vallejo, J; Wetmore, L; Zhao, R	1
Bailey, RA; Blonde, L; Meininger, G; Rupnow, MF; Vijapurkar, U	1
Allison, S; Hoang, KG; Murray, M; Petrovic, N	1
Chen, YR; Li, YH; Liu, Y; Pan, ES; You, WW; Zhang, B; Zhao, PL	1
Copp, SW; Kaufman, MP; Kim, JS; Stone, AJ	1
Choi, H; Jo, H; Ko, HM; Ko, J; Koh, K; Lee, JK; Paek, S	1
Bonomo, RA; Caselli, E; Krishnan, NP; Nguyen, NQ; Prati, F; Rojas, LJ; Romagnoli, C; van den Akker, F	1
Abdelaziz, MA; El-Sayed, NN; Mohareb, RM; Wardakhan, WW	1
Abdel-Ghany, R; Barakat, W; El-Ahwany, E; Gamal, R; Hamad, RS; Mahmoud, O; Nagy, F; Rabia, I; Saber, S	1
Deredge, D; Johnson, KA; Li, J; Wintrode, PL	1
Chow, KBS; Tse, KH; Wise, H	1
Kantevari, S; Pulipati, L; Sriram, D; Yogeeswari, P	1
Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM	1
Bari, F; Farkas, E; Hertelendy, P; Ivánkovits-Kiss, O; Menyhárt, Á; Puskás, T; Tóth, R; Varga, DP; Zölei-Szénási, D	1
Bastos, IM; de Almeida, H; Grellier, P; Leroux, V; Maigret, B; Motta, FN; Santana, JM	1
Kaieda, A; Kanzaki, N; Kori, M; Kuno, H; Mototani, H; Naito, T; Nara, H; Oki, H; Santou, T; Sato, K; Terauchi, J; Uchikawa, O; Yamamoto, Y	1
Garcia, MD; Guddat, LW; Lonhienne, TG; Nouwens, A	1
Han, G; Li, W; Li, X; Yang, B	1
Ambudkar, SV; Chou, AW; Hsiao, SH; Huang, YH; Hung, TH; Li, YQ; Murakami, M; Wu, CP	1
Chen, L; Li, D; Wu, X; Zhong, J	1
Carlock, C; Elzey, BD; Kong, Y; Li, J; Liu, X; Liu, Z; Luo, Q; Mao, F; Wang, R	1
Bogolyubsky, AV; Brovarets, VS; Doroshchuk, RO; Grishchenko, AV; Khomenko, DN; Konovets, AI; Moroz, YS; Pipko, SE; Savych, O; Vybornyi, M; Zhemera, AV	1
Amelung, W; An, NT; Braun, G; Braun, M; Kruse, J; Renaud, FG; Sebesvari, Z	1
Del Mar Montiel-Rozas, M; Diéz-Rojo, MÁ; Pascual, JA; Ros, M; Santísima-Trinidad, ABL	1
Alagusundaram, P; Jaabil, G; Murugavel, S; Ravikumar, C	1
Avdonin, PP; Avdonin, PV; Goncharov, NV; Mironova, GY; Nadeev, AD; Zharkikh, IL	1
Abou El-Alamin, MM; Aboul-Enein, HY; Atia, MA; Sultan, MA	1
Costello, DA; Jones, AC; Pinki, F; Stewart, GS	1
Bergthaler, A; Bigenzahn, JW; César-Razquin, A; Kartnig, F; Kornauth, C; Lercher, A; Pemovska, T; Srndic, I; Staber, PB; Superti-Furga, G; Valent, P	1
Jakubowski, M; Jarzęcki, AA; Kaszuba, A; Sitkowski, J; Wojtczak, A; Łakomska, I	1
Bogucka-Kocka, A; Helmin-Basa, A; Kołodziej, P; Paprocka, R; Wiese-Szadkowska, M	1
Kamra, N; Kumar, D; Rani, S; Sangwan, PL; Singh, A; Singh, SK; Singh, V; Thakral, S	1

Reviews

8 review(s) available for triazoles and thiophenes

Article	Year
[Development of anti tumor agents targeting angiogenesis]. Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:2 Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclohexanes; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Interferon-alpha; Interleukin-12; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Platelet Factor 4; Polysaccharides, Bacterial; Sesquiterpenes; Thalidomide; Thiophenes; Triazines; Triazoles; Tumor Cells, Cultured	1997
Biotransformation reactions of five-membered aromatic heterocyclic rings. Chemical research in toxicology, 2002, Volume: 15, Issue:3 Topics: Animals; Cytochrome P-450 Enzyme System; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Indoles; Isoxazoles; Models, Chemical; Molecular Structure; Oxadiazoles; Oxazoles; Pyrazoles; Pyrroles; Tetrazoles; Thiadiazoles; Thiazoles; Thiophenes; Triazoles; Xenobiotics	2002
[Review of antidepressants from the TCAs to the third generation drugs]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2004, Volume: 6, Issue:4 Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Combinations; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Piperazines; Pyrimidines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Trazodone; Triazoles; Venlafaxine Hydrochloride	2004
GABA A/Bz receptor subtypes as targets for selective drugs. Current medicinal chemistry, 2007, Volume: 14, Issue:25 Topics: Benzodiazepines; Carbolines; Flavones; Indoles; Pyrazoles; Pyridazines; Pyridones; Receptors, GABA-A; Thiophenes; Triazoles	2007
Preventive therapy for breast cancer: a consensus statement. The Lancet. Oncology, 2011, Volume: 12, Issue:5 Topics: Anastrozole; Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Consensus Development Conferences as Topic; Diphosphonates; Estrogen Receptor Modulators; Expert Testimony; Female; Fenretinide; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Nitriles; Norpregnenes; Piperidines; Premenopause; Pyrrolidines; Raloxifene Hydrochloride; Retinoids; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Triazoles	2011
[Oral add-on therapy to metformin in type 2 diabetes mellitus: a direct comparison between canagliflozin and sitagliptin]. Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139 Suppl 2 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Body Weight; Canagliflozin; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endpoint Determination; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pyrazines; Randomized Controlled Trials as Topic; Sitagliptin Phosphate; Thiophenes; Triazoles; Young Adult	2014
Diabetes-Related Composite Quality End Point Attainment: Canagliflozin Versus Sitagliptin Based on a Pooled Analysis of 2 Clinical Trials. Clinical therapeutics, 2015, May-01, Volume: 37, Issue:5 Topics: Blood Pressure; Body Mass Index; Canagliflozin; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrazines; Randomized Controlled Trials as Topic; Sitagliptin Phosphate; Thiophenes; Triazoles	2015
Biotransformation and bioactivation reactions - 2015 literature highlights. Drug metabolism reviews, 2016, Volume: 48, Issue:2 Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles	2016

Trials

12 trial(s) available for triazoles and thiophenes

Article	Year
Effect of canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, on bacteriuria and urinary tract infection in subjects with type 2 diabetes enrolled in a 12-week, phase 2 study. Current medical research and opinion, 2012, Volume: 28, Issue:7 Topics: Bacteriuria; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycosuria; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Triazoles; Urinary Tract Infections	2012
No pharmacokinetic interaction between ipragliflozin and sitagliptin, pioglitazone, or glimepiride in healthy subjects. Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:10 Topics: Adolescent; Adult; Area Under Curve; Body Mass Index; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Interactions; Drug Therapy, Combination; Female; Glucosides; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Pyrazines; Sitagliptin Phosphate; Sulfonylurea Compounds; Thiazolidinediones; Thiophenes; Triazoles	2012
Evaluation of vulvovaginal symptoms and Candida colonization in women with type 2 diabetes mellitus treated with canagliflozin, a sodium glucose co-transporter 2 inhibitor. Current medical research and opinion, 2012, Volume: 28, Issue:7 Topics: Antifungal Agents; Blood Glucose; Canagliflozin; Candida; Candidiasis, Vulvovaginal; Diabetes Mellitus, Type 2; Female; Glucosides; Humans; Hypoglycemic Agents; Middle Aged; Pyrazines; Sitagliptin Phosphate; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Triazoles; Vagina	2012
Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2 Topics: Animals; Antiviral Agents; Cell Line, Tumor; Dogs; Drug Resistance, Viral; Furans; Hepacivirus; Humans; Interferon-alpha; Male; Mutation; Polymorphism, Single Nucleotide; Pyrones; Rats; Rats, Sprague-Dawley; Ribavirin; RNA-Dependent RNA Polymerase; Thiophenes; Triazoles; Viral Nonstructural Proteins	2013
Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: a 52-week randomized trial. Diabetes care, 2013, Volume: 36, Issue:9 Topics: Aged; Blood Glucose; Canagliflozin; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Sulfonylurea Compounds; Thiophenes; Treatment Outcome; Triazoles	2013
Efficacy and safety of canagliflozin compared with placebo and sitagliptin in patients with type 2 diabetes on background metformin monotherapy: a randomised trial. Diabetologia, 2013, Volume: 56, Issue:12 Topics: Adolescent; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Thiophenes; Treatment Outcome; Triazoles	2013
Long-term efficacy and safety of canagliflozin monotherapy in patients with type 2 diabetes inadequately controlled with diet and exercise: findings from the 52-week CANTATA-M study. Current medical research and opinion, 2014, Volume: 30, Issue:2 Topics: Blood Glucose; Blood Pressure; Body Weight; Canagliflozin; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet; Double-Blind Method; Exercise; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Placebos; Pyrazines; Sitagliptin Phosphate; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Treatment Outcome; Triazoles; Triglycerides; Weight Loss	2014
Attainment of diabetes-related quality measures with canagliflozin versus sitagliptin. The American journal of managed care, 2014, Volume: 20, Issue:1 Suppl Topics: Aged; Blood Pressure; Body Mass Index; Canagliflozin; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pyrazines; Quality Indicators, Health Care; Racial Groups; Sitagliptin Phosphate; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Triazoles	2014
Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone. Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:5 Topics: Blood Glucose; Blood Pressure; Canagliflozin; Candidiasis; Diabetes Mellitus, Type 2; Diuretics, Osmotic; Double-Blind Method; Drug Therapy, Combination; Female; Genital Diseases, Female; Genital Diseases, Male; Glucosides; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Pioglitazone; Pyrazines; Sitagliptin Phosphate; Thiazolidinediones; Thiophenes; Treatment Outcome; Triazoles; Weight Loss	2014
Canagliflozin, a sodium glucose co-transporter 2 inhibitor, improves model-based indices of beta cell function in patients with type 2 diabetes. Diabetologia, 2014, Volume: 57, Issue:5 Topics: Adult; Aged; Blood Glucose; C-Peptide; Canagliflozin; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Humans; Insulin-Secreting Cells; Least-Squares Analysis; Male; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Sodium-Glucose Transporter 2; Sulfonylurea Compounds; Thiophenes; Time Factors; Triazoles	2014
The impact of weight loss on weight-related quality of life and health satisfaction: results from a trial comparing canagliflozin with sitagliptin in triple therapy among people with type 2 diabetes. Postgraduate medicine, 2014, Volume: 126, Issue:3 Topics: Adult; Age Factors; Aged; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Health Behavior; Humans; Hypoglycemic Agents; Male; Middle Aged; Personal Satisfaction; Pyrazines; Quality of Life; Self Efficacy; Sex Factors; Sexual Behavior; Sitagliptin Phosphate; Thiophenes; Triazoles; Weight Loss	2014
Diabetes-related quality measure attainment: canagliflozin versus sitagliptin based on a pooled analysis of 2 clinical trials. The American journal of managed care, 2014, Volume: 20, Issue:13 Suppl Topics: Blood Pressure; Body Mass Index; Body Weight; Canagliflozin; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipoproteins, LDL; Male; Middle Aged; Pyrazines; Sitagliptin Phosphate; Thiophenes; Treatment Outcome; Triazoles	2014

Other Studies

93 other study(ies) available for triazoles and thiophenes

Article	Year
Mutagenicity assays on fluorescent whitening agents using microorganisms. Environmental quality and safety. Supplement, 1975, Volume: 4 Topics: Biphenyl Compounds; Coloring Agents; Escherichia coli; Genes; Mutagens; Neurospora crassa; Quinolines; Saccharomyces cerevisiae; Salmonella typhimurium; Stilbenes; Thiophenes; Triazoles	1975
Benzo[b]thiophenes, Part I: Synthesis and antimicrobial activity of benzo[b]thienyl-1,3,4-oxadiazole, -1,2,4-triazoline, and -thiazoline derivatives. Archiv der Pharmazie, 1992, Volume: 325, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Candida albicans; Microbial Sensitivity Tests; Oxadiazoles; Thiazoles; Thiophenes; Triazoles	1992
Research for new antichagasic drugs. Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:8 Topics: Animals; Azoles; Benzimidazoles; Chagas Disease; Imidazoles; Indazoles; Indoles; Mice; Nifurtimox; Nitro Compounds; Thiophenes; Triazoles; Trypanocidal Agents; Trypanosoma cruzi	1991
Triazolobenzo- and triazolothienodiazepines as potent antagonists of platelet activating factor. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Animals; Azepines; Benzodiazepines; Blood Platelets; Bronchoconstriction; Chemical Phenomena; Chemistry; Dogs; Guinea Pigs; Male; Molecular Conformation; Molecular Structure; Platelet Activating Factor; Structure-Activity Relationship; Thiophenes; Triazoles	1991
Thienotriazolodiazepines as platelet-activating factor antagonists. Steric limitations for the substituent in position 2. Journal of medicinal chemistry, 1991, Volume: 34, Issue:4 Topics: Animals; Azepines; Guinea Pigs; Indicators and Reagents; Lung; Magnetic Resonance Spectroscopy; Molecular Structure; Platelet Activating Factor; Structure-Activity Relationship; Thiophenes; Triazoles	1991
[Thiophene as a structural element in physiologically active substances. 15. Thiophene analogs of an anxiolytic acting 1,2,4-triazolo[4,3-b]pyridazine]. Archiv der Pharmazie, 1985, Volume: 318, Issue:3 Topics: Animals; Anti-Anxiety Agents; Chemical Phenomena; Chemistry; Pyridazines; Thiophenes; Triazoles	1985
PAF antagonistic activity of some thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines. Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:5 Topics: Azepines; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Thiophenes; Triazoles	1987
[Antibacterial activity of new derivatives of nitrofuran and nitrothiophen]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1973, Volume: 50, Issue:2 Topics: Anti-Bacterial Agents; Escherichia coli; Furazolidone; Nitro Compounds; Nitrofurans; Staphylococcus; Thiophenes; Triazoles	1973
Radiation chemistry of nitrogen and sulfur heterocyclics. Radiation research, 1973, Volume: 56, Issue:1 Topics: Chromatography, Gas; Free Radicals; Heterocyclic Compounds; Imidazoles; Nitrogen; Pyrazines; Pyrazoles; Pyrimidines; Pyrroles; Radiochemistry; Sulfur; Tetrazoles; Thiazoles; Thiophenes; Triazines; Triazoles	1973
[Studies on nitrothiophene and nitrofuran derivatives. 3. Conversion of 5-nitrothiophene-2- and 5-nitrofuran-2-iminocarbonic acid ethyl ester with semicarbazide and thiosemicarbazides and antimicrobial properties of compounds]. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1968, Volume: 301, Issue:6 Topics: Amidines; Bacteria; Fungi; Helminths; Nitrofurans; Semicarbazides; Thiophenes; Thiosemicarbazones; Triazoles	1968
Pteridines. 8. Some 2,4,7-triamino-6-heteroarylpteridines. Journal of medicinal chemistry, 1968, Volume: 11, Issue:3 Topics: Chromatography, Paper; Furans; Hydrogen-Ion Concentration; Imidazoles; Oxazoles; Pteridines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Spectrum Analysis; Thiazoles; Thiophenes; Triazoles; Ultraviolet Rays	1968
Synthesis of aminothienopyrimidine and thienotriazolopyrimidine derivatives as potential anticonvulsant agents. Die Pharmazie, 1996, Volume: 51, Issue:1 Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Male; Mice; Motor Activity; Pyrimidines; Rats; Seizures; Thiophenes; Triazoles	1996
New azole antifungals. 2. Synthesis and antifungal activity of heterocyclecarboxamide derivatives of 3-amino-2-aryl-1-azolyl-2-butanol. Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11 Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candidiasis; Colony Count, Microbial; Fungi; Male; Mice; Molecular Conformation; Pyrimidinones; Rats; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiophenes; Triazoles	1998
Effect of antiangiogenic agents on experimental animal models of hepatocellular carcinoma. Annals of the Academy of Medicine, Singapore, 1999, Volume: 28, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Division; Cyclohexanes; Liver Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Sesquiterpenes; Suramin; Thiophenes; Triazoles	1999
The effect of minor-groove hydrogen-bond acceptors and donors on the stability and replication of four unnatural base pairs. Journal of the American Chemical Society, 2003, May-21, Volume: 125, Issue:20 Topics: Base Pairing; Benzofurans; Circular Dichroism; DNA; Hydrogen Bonding; Indoles; Kinetics; Nucleotides; Thiophenes; Triazoles	2003
THE REACTION OF INDOLE AND T2 BACTERIOPHAGE. Biochemistry, 1964, Volume: 3 Topics: Adsorption; Antimetabolites; Bacteriophage T4; Coliphages; Furans; Imidazoles; Indoles; Naphthalenes; Pharmacology; Purines; Quinolines; Research; Thiophenes; Triazoles	1964
Synthesis and potential antimycotic activity of 4-substituted-3-(thiophene-2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones. Acta pharmaceutica (Zagreb, Croatia), 2004, Volume: 54, Issue:3 Topics: Antifungal Agents; Chemistry, Pharmaceutical; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Semicarbazides; Technology, Pharmaceutical; Thiones; Thiophenes; Triazoles	2004
Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia. European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2 Topics: Acetates; Acrylamides; Animals; Benzyl Compounds; Dimethyl Sulfoxide; Extracellular Fluid; Formaldehyde; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Injections, Intraventricular; Male; Mice; Microdialysis; Misoprostol; Naphthalenes; Pain Measurement; Periaqueductal Gray; Prostaglandin Antagonists; Receptors, Prostaglandin E; Thiophenes; Triazoles; Xanthones	2006
Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6 Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Survival; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclooxygenase 2; Enzyme Induction; Epithelial Cells; Gene Expression; Kidney Glomerulus; Nephrosis; Phosphoric Diester Hydrolases; Proteinuria; Puromycin Aminonucleoside; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Transfection; Triazoles	2006
Medical management of depression. The New England journal of medicine, 2006, Feb-09, Volume: 354, Issue:6 Topics: Chemical and Drug Induced Liver Injury; Depressive Disorder; Duloxetine Hydrochloride; Humans; Liver Function Tests; Piperazines; Selective Serotonin Reuptake Inhibitors; Thiophenes; Triazoles	2006
Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation. Journal of cellular physiology, 2007, Volume: 210, Issue:1 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Apoptosis; Carbazoles; Caspases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Lung; Nicotiana; Pyrroles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Small Interfering; Signal Transduction; Smoke; Thiophenes; Triazoles	2007
The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells. Experimental cell research, 2007, Aug-15, Volume: 313, Issue:14 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclic AMP Response Element-Binding Protein; Dinoprostone; Early Growth Response Protein 1; Extracellular Signal-Regulated MAP Kinases; Humans; Promoter Regions, Genetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Thiophenes; Transcription, Genetic; Triazoles	2007
Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore. Journal of medicinal chemistry, 2007, Aug-09, Volume: 50, Issue:16 Topics: Aminopeptidases; Angiogenesis Inhibitors; Animals; Aorta, Thoracic; Capillaries; Cell Proliferation; Crystallography, X-Ray; Endothelial Cells; Endothelium, Vascular; Furans; In Vitro Techniques; Male; Metalloendopeptidases; Models, Molecular; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles; Thiophenes; Triazoles	2007
Structure-activity relationship development of dihaloaryl triazole compounds as insecticides and acaricides. 1. Phenyl thiophen-2-yl triazoles. Journal of agricultural and food chemistry, 2007, Sep-05, Volume: 55, Issue:18 Topics: Acari; Animals; Insecticides; Structure-Activity Relationship; Thiophenes; Triazoles	2007
Renal sympathetic nerve activity modulates afferent renal nerve activity by PGE2-dependent activation of alpha1- and alpha2-adrenoceptors on renal sensory nerve fibers. American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:4 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Dinoprostone; Indomethacin; Kidney; Male; Neurons, Afferent; Neurons, Efferent; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Substance P; Thiophenes; Triazoles	2007
Synthesis of oxadiazoles, thiadiazoles and triazoles derived from benzo[b]thiophene. Molecules (Basel, Switzerland), 2005, Sep-30, Volume: 10, Issue:9 Topics: Oxadiazoles; Thiadiazoles; Thiophenes; Triazoles	2005
New drug update: 2007. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2008, Volume: 23, Issue:4 Topics: Aged; Amides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Antiparkinson Agents; Antipsychotic Agents; Drug Approval; Fumarates; Humans; Hypoglycemic Agents; Isoxazoles; Macular Degeneration; Paliperidone Palmitate; Pyrazines; Pyrimidines; Ranibizumab; Sitagliptin Phosphate; Tetrahydronaphthalenes; Thiophenes; Triazoles; United States	2008
The role of PGE2 receptor EP4 in pathologic ocular angiogenesis. Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:11 Topics: Animals; Animals, Newborn; Cell Proliferation; Choroid; Choroidal Neovascularization; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Laser Coagulation; Male; Mice; Neuroglia; Oxygen; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Retinal Neovascularization; Retinal Vessels; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A	2009
Lubiprostone targets prostanoid EP₄ receptors in ovine airways. British journal of pharmacology, 2011, Volume: 162, Issue:2 Topics: Adenylyl Cyclases; Alprostadil; Animals; Chloride Channels; CLC-2 Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Lubiprostone; Molecular Targeted Therapy; Receptors, Prostaglandin E, EP4 Subtype; Respiratory Mucosa; Sheep; Thiophenes; Trachea; Triazoles	2011
Electrochemical polymerization of (2-dodecyl-4, 7-di (thiophen-2-yl)-2H-benzo[d][1,2,3] triazole): a novel matrix for biomolecule immobilization. Macromolecular bioscience, 2010, Dec-08, Volume: 10, Issue:12 Topics: Amino Acids; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrochemistry; Enzymes, Immobilized; Glucose Oxidase; Kinetics; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Oxygen Consumption; Polymerization; Thiophenes; Triazoles; Yeasts	2010
Potent and selective 5-LO inhibitor bearing benzothiophene pharmacophore: discovery of MK-5286. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Administration, Oral; Animals; Arachidonate 5-Lipoxygenase; Dogs; Drug Evaluation, Preclinical; Humans; Hydrocarbons, Fluorinated; Lipoxygenase Inhibitors; Rats; Structure-Activity Relationship; Thiophenes; Triazoles	2010
Studying synergism of methyl linked cyclohexyl thiophenes with triazole: synthesis and their cdk5/p25 inhibition activity. European journal of medicinal chemistry, 2011, Volume: 46, Issue:6 Topics: Cyclin-Dependent Kinase 5; Drug Synergism; Humans; Molecular Structure; Nerve Tissue Proteins; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Triazoles	2011
Synthesis and chemical characterisation of some new diheteroaryl thienothiophene derivatives. Molecules (Basel, Switzerland), 2011, Sep-08, Volume: 16, Issue:9 Topics: Imidazoles; Pyrazoles; Pyrimidines; Thiophenes; Transition Temperature; Triazoles	2011
Triazole-linked-thiophene conjugate of calix[4]arene: its selective recognition of Zn2+ and as biomimetic model in supporting the events of the metal detoxification and oxidative stress involving metallothionein. The Journal of organic chemistry, 2011, Dec-16, Volume: 76, Issue:24 Topics: Biomimetics; Buffers; Calixarenes; Crystallography, X-Ray; Electrons; Humans; Hydrogen Peroxide; Imines; Inactivation, Metabolic; Magnetic Resonance Spectroscopy; Metallothionein; Models, Molecular; Oxidative Stress; Quantum Theory; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Thermodynamics; Thiophenes; Triazoles; Zinc	2011
Biochemical study of the comparative inhibition of hepatitis C virus RNA polymerase by VX-222 and filibuvir. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2 Topics: Antiviral Agents; Binding Sites; Cell Line, Tumor; Cyclohexanols; Drug Resistance, Viral; Enzyme Inhibitors; Hepacivirus; Humans; Models, Molecular; Mutation; Pyrones; Replicon; RNA-Dependent RNA Polymerase; RNA, Viral; Templates, Genetic; Thiophenes; Triazoles	2012
Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors. Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chymotrypsin; Drug Stability; Humans; Naphthoquinones; Proteasome Inhibitors; Rabbits; Small Molecule Libraries; Structure-Activity Relationship; Sulfonamides; Tetrazoles; Thioglycolates; Thiophenes; Triazoles	2012
Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma. PloS one, 2012, Volume: 7, Issue:1 Topics: 16,16-Dimethylprostaglandin E2; Autocrine Communication; Biphenyl Compounds; Blotting, Western; Calcium; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic AMP; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Immunohistochemistry; In Vitro Techniques; Neuroblastoma; Phosphorylation; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Reverse Transcriptase Polymerase Chain Reaction; Tandem Mass Spectrometry; Thiophenes; Triazoles	2012
Sensitivity to silthiofam, tebuconazole and difenoconazole of Gaeumannomyces graminis var. tritici isolates from China. Pest management science, 2012, Volume: 68, Issue:8 Topics: Ascomycota; Dioxolanes; Drug Resistance, Fungal; Fungicides, Industrial; Microbial Sensitivity Tests; Organosilicon Compounds; Plant Diseases; Thiophenes; Triazoles; Triticum	2012
Design, synthesis, and structure-activity correlations of novel dibenzo[b,d]furan, dibenzo[b,d]thiophene, and N-methylcarbazole clubbed 1,2,3-triazoles as potent inhibitors of Mycobacterium tuberculosis. Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8 Topics: Antitubercular Agents; Benzofurans; Carbazoles; Cell Line, Tumor; Click Chemistry; Cytostatic Agents; Drug Design; Humans; Mycobacterium tuberculosis; Thiophenes; Triazoles	2012
Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement. Bioorganic & medicinal chemistry letters, 2012, Dec-01, Volume: 22, Issue:23 Topics: Amides; Cathepsins; Half-Life; Humans; Microsomes, Liver; Protease Inhibitors; Protein Binding; Structure-Activity Relationship; Thiophenes; Triazoles	2012
Activation of prostaglandin E receptor 4 triggers secretion of gut hormone peptides GLP-1, GLP-2, and PYY. Endocrinology, 2013, Volume: 154, Issue:1 Topics: Animals; Cells, Cultured; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Intestinal Mucosa; Mice; Peptide YY; Real-Time Polymerase Chain Reaction; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles	2013
Synthesis and biological evaluation of thieno [2',3':4,5]pyrimido[1,2-b][1,2,4]triazines and thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidines as anti-inflammatory and analgesic agents. European journal of medicinal chemistry, 2013, Volume: 62 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Male; Molecular Structure; Pyrimidines; Rats; Rats, Wistar; Structure-Activity Relationship; Thiophenes; Triazines; Triazoles	2013
New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol. European journal of medicinal chemistry, 2013, Volume: 62 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiophenes; Triazoles	2013
Coculture with endothelial cells enhances osteogenic differentiation of periodontal ligament stem cells via cyclooxygenase-2/prostaglandin E2/vascular endothelial growth factor signaling under hypoxia. Journal of periodontology, 2013, Volume: 84, Issue:12 Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endothelial Cells; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Nitrobenzenes; Osteogenesis; Periodontal Ligament; Prostaglandin Antagonists; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Stem Cells; Sulfonamides; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A; Xanthones	2013
The top 10 drug trends right now. Nursing management, 2013, Volume: 44, Issue:7 Topics: Ado-Trastuzumab Emtansine; Antibodies, Monoclonal, Humanized; Azepines; Biphenyl Compounds; Canagliflozin; Cholesterol Ester Transfer Proteins; Dimethyl Fumarate; Drug Approval; Forecasting; Fumarates; gamma-Cyclodextrins; Glucosides; Humans; Lactones; Maytansine; Pyridines; Sofosbuvir; Sugammadex; Thiophenes; Trastuzumab; Triazoles; United States; United States Food and Drug Administration; Uridine Monophosphate	2013
High-crystalline medium-band-gap polymers consisting of benzodithiophene and benzotriazole derivatives for organic photovoltaic cells. ACS applied materials & interfaces, 2013, Dec-26, Volume: 5, Issue:24 Topics: Electrochemical Techniques; Fullerenes; Polymers; Polystyrenes; Quantum Theory; Solar Energy; Spectrum Analysis, Raman; Thiophenes; Tin Compounds; Triazoles	2013
Regulation of rat intrapulmonary arterial tone by arachidonic acid and prostaglandin E2 during hypoxia. PloS one, 2013, Volume: 8, Issue:8 Topics: Animals; Arachidonic Acid; Calcium; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Hypoxia; Male; Muscle Tonus; Oxytocics; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Prostaglandin E; Thiophenes; Triazoles; Vasoconstriction; Xanthones	2013
Post-infection activities of fungicides against Cercospora arachidicola of peanut (Arachis hypogaea). Pest management science, 2014, Volume: 70, Issue:8 Topics: Arachis; Ascomycota; Carbamates; Fungicides, Industrial; Plant Diseases; Pyrazoles; Strobilurins; Thiophenes; Triazoles	2014
Targeting small cell lung cancer harboring PIK3CA mutation with a selective oral PI3K inhibitor PF-4989216. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Feb-01, Volume: 20, Issue:3 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Immunoblotting; Lung Neoplasms; Mice; Mice, SCID; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Small Cell Lung Carcinoma; Thiophenes; Triazoles; Xenograft Model Antitumor Assays	2014
Vitamin a is a negative regulator of osteoblast mineralization. PloS one, 2013, Volume: 8, Issue:12 Topics: Animals; Benzoates; Benzothiazoles; Calcification, Physiologic; Cell Line; Core Binding Factor Alpha 1 Subunit; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Femur; Humans; Male; Osteoblasts; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Signal Transduction; Sp7 Transcription Factor; Thiophenes; Transcription Factors; Triazoles; Vitamin A; Vitamins	2013
Use of vibrational spectroscopy to study 4-benzyl-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione: A combined theoretical and experimental approach. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, May-21, Volume: 126 Topics: Models, Molecular; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thiones; Thiophenes; Triazoles	2014
Thiophenyl-substituted triazolyl-thione L-alanine: asymmetric synthesis, aggregation and biological properties. Amino acids, 2014, Volume: 46, Issue:10 Topics: Alanine; Amino Acids, Aromatic; Antiviral Agents; Circular Dichroism; Drug Design; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Nephelometry and Turbidimetry; RNA; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Thiophenes; Triazoles	2014
New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. European journal of medicinal chemistry, 2014, Sep-12, Volume: 84 Topics: Anti-Bacterial Agents; Antioxidants; Bacillus cereus; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Schiff Bases; Semicarbazides; Staphylococcus aureus; Structure-Activity Relationship; Sulfhydryl Compounds; Thiophenes; Triazoles	2014
Synthesis and antioxidant activities of some new triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings. Journal of enzyme inhibition and medicinal chemistry, 2015, Volume: 30, Issue:3 Topics: Antioxidants; Benzimidazoles; Dose-Response Relationship, Drug; Heterocyclic Compounds; Molecular Structure; Structure-Activity Relationship; Thiophenes; Triazoles	2015
Synthesis and antiproliferative activity of some new thieno[2,3-d]pyrimidin-4(3H)-ones containing 1,2,4-triazole and 1,3,4-thiadiazole moiety. European journal of medicinal chemistry, 2014, Oct-30, Volume: 86 Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; HT29 Cells; Humans; Molecular Structure; Pyrimidinones; Structure-Activity Relationship; Thiadiazoles; Thiophenes; Triazoles	2014
Cross-genotypic examination of hepatitis C virus polymerase inhibitors reveals a novel mechanism of action for thumb binders. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12 Topics: Antiviral Agents; Benzimidazoles; Benzofurans; Cyclohexanols; Drug Resistance, Viral; Enzyme Inhibitors; Genotype; Hepacivirus; Humans; Purines; Pyridazines; Pyrones; Recombinant Proteins; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Sulfonamides; Thiophenes; Triazoles; Viral Proteins	2014
Triazole-based compound as a candidate to develop novel medicines to treat toxoplasmosis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12 Topics: Animals; Antiprotozoal Agents; Cell Line; Dose-Response Relationship, Drug; Fibroblasts; HeLa Cells; Humans; Inhibitory Concentration 50; Mice; Molecular Docking Simulation; Parasitic Sensitivity Tests; Protozoan Proteins; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship; Sulfadiazine; Thiophenes; Toxoplasma; Triazoles	2014
Evidence for the chain-growth synthesis of statistical π-conjugated donor-acceptor copolymers. Macromolecular rapid communications, 2015, Volume: 36, Issue:1 Topics: Catalysis; Models, Chemical; Nickel; Oxidation-Reduction; Polymerization; Polymers; Quantum Theory; Thiophenes; Triazoles	2015
Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons. Biochemical and biophysical research communications, 2015, Jan-02, Volume: 456, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Ileum; Male; Neurons, Afferent; Nodose Ganglion; Ondansetron; Patch-Clamp Techniques; Prostaglandins; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Sensory Receptor Cells; Serotonin; Signal Transduction; Stomach; Thiophenes; Triazoles; Visceral Afferents; Xanthones	2015
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization. Pharmacological research, 2014, Volume: 90 Topics: Alprostadil; Animals; Azetidines; Colon; Dinoprostone; Female; In Vitro Techniques; Male; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles	2014
Activation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue. Journal of lipid research, 2015, Volume: 56, Issue:2 Topics: Adipose Tissue; Animals; Chemokine CCL3; Chemokine CXCL10; Chemokines; Dinoprostone; In Vitro Techniques; Interleukin-10; Interleukin-6; Interleukin-8; Male; Pyrrolidinones; Receptors, Prostaglandin E, EP4 Subtype; Serum Amyloid A Protein; Signal Transduction; Tetrazoles; Thiophenes; Triazoles	2015
Antagonist of prostaglandin E2 receptor 4 induces metabolic alterations in liver of mice. Journal of proteome research, 2015, Mar-06, Volume: 14, Issue:3 Topics: Animals; Liver; Male; Mice; Mice, Inbred BALB C; Proton Magnetic Resonance Spectroscopy; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles	2015
Prostaglandin E2 promotes proliferation of skeletal muscle myoblasts via EP4 receptor activation. Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:10 Topics: Acetylcysteine; Alprostadil; Animals; Cell Proliferation; Cells, Cultured; Dinoprostone; G1 Phase Cell Cycle Checkpoints; Immunohistochemistry; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myoblasts; Reactive Oxygen Species; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Thiophenes; Triazoles	2015
Prostanoids regulate angiogenesis acting primarily on IP and EP4 receptors. Microvascular research, 2015, Volume: 101 Topics: Benzyl Compounds; Cell Movement; Dinoprostone; Endothelial Cells; Epoprostenol; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Neovascularization, Pathologic; Neovascularization, Physiologic; Prostaglandins I; Real-Time Polymerase Chain Reaction; Receptors, Epoprostenol; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles; Xanthones	2015
Design, synthesis and biological evaluation of novel 1,2,4-triazolo [3,4-b][1,3,4] thiadiazines bearing furan and thiophene nucleus. European journal of medicinal chemistry, 2015, Oct-20, Volume: 103 Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Furans; Hep G2 Cells; Humans; Molecular Structure; Structure-Activity Relationship; Thiadiazines; Thiophenes; Triazoles	2015
Combined, but not individual, blockade of ASIC3, P2X, and EP4 receptors attenuates the exercise pressor reflex in rats with freely perfused hindlimb muscles. Journal of applied physiology (Bethesda, Md. : 1985), 2015, Dec-01, Volume: 119, Issue:11 Topics: Acid Sensing Ion Channels; Animals; Blood Pressure; Cnidarian Venoms; Decerebrate State; Hindlimb; Muscle, Skeletal; Neurons, Afferent; Physical Exertion; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Prostaglandin E, EP4 Subtype; Receptors, Purinergic P2X; Reflex; Thiophenes; Triazoles	2015
Efficient Hole-Transporting Materials with Triazole Core for High-Efficiency Perovskite Solar Cells. Chemistry, an Asian journal, 2016, Feb-18, Volume: 11, Issue:4 Topics: Calcium Compounds; Electric Power Supplies; Electrons; Equipment Design; Oxides; Solar Energy; Thiophenes; Titanium; Triazoles	2016
Crystal Structures of KPC-2 and SHV-1 β-Lactamases in Complex with the Boronic Acid Transition State Analog S02030. Antimicrobial agents and chemotherapy, 2016, Jan-04, Volume: 60, Issue:3 Topics: beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Carbapenems; Catalytic Domain; Cephalosporins; Crystallography, X-Ray; Klebsiella pneumoniae; Protein Structure, Tertiary; Thiophenes; Triazoles	2016
The Knoevenagel reaction of cyanoacetylhydrazine with pregnenolone: Synthesis of thiophene, thieno[2,3-d]pyrimidine, 1,2,4-triazole, pyran and pyridine derivatives with anti-inflammatory and anti-ulcer activities. Steroids, 2016, Volume: 107 Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Hydrazines; Pandalidae; Pregnenolone; Thiophenes; Triazoles	2016
BLOCKADE OF PGE2, PGD2 RECEPTORS CONFERS PROTECTION AGAINST PREPATENT SCHISTOSOMIASIS MANSONI IN MICE. Journal of the Egyptian Society of Parasitology, 2015, Volume: 45, Issue:3 Topics: Animals; Cytokines; Gene Expression Regulation; Indoles; Mice; Mice, Inbred C57BL; Prostaglandin Antagonists; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Schistosomiasis mansoni; T-Lymphocytes, Helper-Inducer; Thiophenes; Triazoles; Xanthones	2015
Hydrogen/Deuterium Exchange Kinetics Demonstrate Long Range Allosteric Effects of Thumb Site 2 Inhibitors of Hepatitis C Viral RNA-dependent RNA Polymerase. The Journal of biological chemistry, 2016, May-06, Volume: 291, Issue:19 Topics: Allosteric Regulation; Binding Sites; Deuterium Exchange Measurement; Furans; Hepacivirus; Kinetics; Pyrones; RNA-Dependent RNA Polymerase; RNA, Viral; Thiophenes; Triazoles; Viral Nonstructural Proteins	2016
PGE2 released by primary sensory neurons modulates Toll-like receptor 4 activities through an EP4 receptor-dependent process. Journal of neuroimmunology, 2016, Apr-15, Volume: 293 Topics: Animals; Cells, Cultured; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP4 Subtype; Sensory Receptor Cells; Sulfonamides; Thiophenes; Toll-Like Receptor 4; Triazoles; Tumor Necrosis Factor-alpha	2016
Click-based synthesis and antitubercular evaluation of novel dibenzo[b,d]thiophene-1,2,3-triazoles with piperidine, piperazine, morpholine and thiomorpholine appendages. Bioorganic & medicinal chemistry letters, 2016, 06-01, Volume: 26, Issue:11 Topics: Antitubercular Agents; Cell Survival; Click Chemistry; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Morpholines; Mycobacterium tuberculosis; Piperazine; Piperazines; Piperidines; Structure-Activity Relationship; Thiophenes; Triazoles	2016
New drugs 2016, part 2. Nursing, 2016, Volume: 46, Issue:7 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzimidazoles; Carbamates; Drug Approval; Drug Therapy; Humans; Imidazoles; Nitriles; Pyridines; Pyrrolidines; Quinolones; Thiophenes; Triazoles; United States; United States Food and Drug Administration; Valine	2016
Contribution of prostanoid signaling to the evolution of spreading depolarization and the associated cerebral blood flow response. Scientific reports, 2016, 08-10, Volume: 6 Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Laser-Doppler Flowmetry; Male; Nitrobenzenes; Prosencephalon; Prostaglandins; Pyrazoles; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Thiophenes; Triazoles	2016
Identification of novel Trypanosoma cruzi prolyl oligopeptidase inhibitors by structure-based virtual screening. Journal of computer-aided molecular design, 2016, Volume: 30, Issue:12 Topics: Animals; Benzene Derivatives; Binding Sites; Catalytic Domain; Databases, Chemical; Humans; Molecular Dynamics Simulation; Molecular Structure; Prolyl Oligopeptidases; Protein Binding; Pyrimidines; Sequence Homology, Amino Acid; Serine Endopeptidases; Serine Proteinase Inhibitors; Small Molecule Libraries; Structure-Activity Relationship; Sulfonamides; Swine; Thiophenes; Triazoles; Trypanocidal Agents; Trypanosoma cruzi	2016
Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach. Journal of medicinal chemistry, 2017, 01-26, Volume: 60, Issue:2 Topics: Animals; Cartilage; Cattle; Chelating Agents; Collagen; Drug Design; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Pyrimidines; Pyrimidinones; Quinazolines; Thiophenes; Triazoles; Zinc	2017
Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families. Proceedings of the National Academy of Sciences of the United States of America, 2017, 02-14, Volume: 114, Issue:7 Topics: Acetolactate Synthase; Arabidopsis Proteins; Benzoates; Catalytic Domain; Crystallography, X-Ray; Herbicides; Imidazoles; Kinetics; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Pyrimidines; Quinolines; Sulfonylurea Compounds; Thiamine Pyrophosphate; Thiophenes; Triazoles	2017
The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2017, Volume: 46, Issue:10 Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Proliferation; Dinoprostone; Humans; Mouth Neoplasms; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles; Tumor Cells, Cultured	2017
Overexpression of ATP-Binding Cassette Subfamily G Member 2 Confers Resistance to Phosphatidylinositol 3-Kinase Inhibitor PF-4989216 in Cancer Cells. Molecular pharmaceutics, 2017, 07-03, Volume: 14, Issue:7 Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Drug Resistance, Neoplasm; HEK293 Cells; Humans; MCF-7 Cells; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Thiophenes; Triazoles	2017
L161982 alleviates collagen-induced arthritis in mice by increasing Treg cells and down-regulating Interleukin-17 and monocyte-chemoattractant protein-1 levels. BMC musculoskeletal disorders, 2017, Nov-16, Volume: 18, Issue:1 Topics: Animals; Ankle Joint; Arthritis, Experimental; Arthritis, Rheumatoid; Celecoxib; Cell Differentiation; Cell Proliferation; Chemokine CCL2; Collagen Type II; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Female; Humans; Injections, Intraperitoneal; Interleukin-17; Mice; Mice, Inbred DBA; Receptors, Prostaglandin E, EP4 Subtype; Severity of Illness Index; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Thiophenes; Triazoles	2017
Plk1 Inhibition Enhances the Efficacy of BET Epigenetic Reader Blockade in Castration-Resistant Prostate Cancer. Molecular cancer therapeutics, 2018, Volume: 17, Issue:7 Topics: Animals; Azepines; beta Catenin; Cell Cycle Proteins; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Nuclear Proteins; Polo-Like Kinase 1; Prostatic Neoplasms, Castration-Resistant; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Receptors, Androgen; Signal Transduction; Thiophenes; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays	2018
Facile One-Pot Parallel Synthesis of 3-Amino-1,2,4-triazoles. ACS combinatorial science, 2018, 07-09, Volume: 20, Issue:7 Topics: Alkylation; Molecular Structure; Small Molecule Libraries; Temperature; Thiophenes; Thiourea; Time Factors; Triazoles	2018
Does sea-dyke construction affect the spatial distribution of pesticides in agricultural soils? - A case study from the Red River Delta, Vietnam. Environmental pollution (Barking, Essex : 1987), 2018, Volume: 243, Issue:Pt B Topics: Agriculture; Chlorpyrifos; Environmental Monitoring; Environmental Pollution; Floods; Oryza; Pesticides; Pyrimidines; Rivers; Soil; Soil Pollutants; Specimen Handling; Strobilurins; Thiophenes; Triazoles; Vietnam; Water Pollutants, Chemical	2018
Impact of foliar fungicides on target and non-target soil microbial communities in cucumber crops. Ecotoxicology and environmental safety, 2018, Dec-30, Volume: 166 Topics: Benzamides; Crops, Agricultural; Cucumis sativus; Fungicides, Industrial; Microbiota; Plant Diseases; Pyrazoles; Pyridines; Soil; Soil Microbiology; Thiophenes; Triazoles	2018
Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic thiophene derivative containing 1,2,3-triazole and pyridine moieties as a potential human topois Computational biology and chemistry, 2019, Volume: 79 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Density Functional Theory; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Molecular Docking Simulation; Molecular Structure; Poly-ADP-Ribose Binding Proteins; Pyridines; Structure-Activity Relationship; Sulfur; Thiophenes; Topoisomerase II Inhibitors; Triazoles	2019
Enhancement by Hydrogen Peroxide of Calcium Signals in Endothelial Cells Induced by 5-HT1B and 5-HT2B Receptor Agonists. Oxidative medicine and cellular longevity, 2019, Volume: 2019 Topics: Acetylcysteine; Benzoxazoles; Calcium; Calcium Signaling; Fluorescence; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Indoles; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Triazoles; Vanadates	2019
Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs Using High-performance Liquid Chromatography. Combinatorial chemistry & high throughput screening, 2020, Volume: 23, Issue:10 Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Clotrimazole; Humans; Hydrocarbons, Brominated; Imidazoles; Ketoconazole; Liquid-Liquid Extraction; Molecular Structure; Thiophenes; Triazoles; Voriconazole	2020
Inhibition of Urea Transporter (UT)-B Modulates LPS-Induced Inflammatory Responses in BV2 Microglia and N2a Neuroblastoma Cells. Neurochemical research, 2021, Volume: 46, Issue:6 Topics: Animals; Cell Line, Tumor; Inflammation; Interleukin-6; Lipopolysaccharides; Membrane Transport Proteins; Mice; Microglia; Neuroblastoma; Nitric Oxide; Pyrimidines; Thiophenes; Triazoles; Tumor Necrosis Factor-alpha; Urea Transporters	2021
Metabolic drug survey highlights cancer cell dependencies and vulnerabilities. Nature communications, 2021, 12-14, Volume: 12, Issue:1 Topics: Biomarkers, Tumor; Cell Survival; Cluster Analysis; Fatty Acids; Genotype; Humans; Leukemia, Myeloid; Monocarboxylic Acid Transporters; Phenotype; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Pyrimidinones; Pyrrolidines; Signal Transduction; Small Molecule Libraries; Symporters; Systems Analysis; Thiophenes; Triazoles; Tumor Cells, Cultured	2021
Factors Affecting the Stability of Platinum(II) Complexes with 1,2,4-Triazolo[1,5- International journal of molecular sciences, 2022, Mar-26, Volume: 23, Issue:7 Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Oxides; Platinum; Pyrimidines; Sulfoxides; Thiophenes; Triazoles	2022
Evaluation of Anthelmintic and Anti-Inflammatory Activity of 1,2,4-Triazole Derivatives. Molecules (Basel, Switzerland), 2022, Jul-13, Volume: 27, Issue:14 Topics: Anthelmintics; Anti-Infective Agents; Anti-Inflammatory Agents; Humans; Imidazoles; Leukocytes, Mononuclear; Sulfonamides; Thiophenes; Triazoles; Tumor Necrosis Factor-alpha	2022
Synthesis, Biological Activity and Molecular Docking Studies of Heterocyclic Chalcones. Chemistry & biodiversity, 2022, Volume: 19, Issue:9 Topics: Aldehydes; Anti-Infective Agents; Antineoplastic Agents; Candida albicans; Chalcone; Chalcones; Imidazoles; Indoles; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship; Thiophenes; Triazoles	2022