Page last updated: 2024-08-24

triazoles and tanespimycin

triazoles has been researched along with tanespimycin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's13 (81.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Adler, M; Arnaiz, DO; Biroc, SL; Bryant, J; Buckman, B; Chang, Z; Chen, D; Dinter, H; Emayan, K; Feldman, RI; Ferrer, M; Ge, XS; Gu, JM; Li, WW; Mintzer, B; Polokoff, MA; Sato, T; Shen, J; Tseng, JL; Whitlow, M; Wu, JM; Yuan, S; Zhu, D1
Arnould, L; Coudert, B; Favier, L; Fumoleau, P; Guiu, S1
Baer, MR; Bansal, H; Bansal, S; Barsoum, J; Battiwalla, M; Blackman, RK; Foley, KP; Giles, FJ; Kelly, K; Lee, KP; Padmanabhan, S; Proia, DA; Rao, M; Sang, J; Swords, R; Tomlinson, GE; Ying, W1
Acquaviva, J; Barsoum, J; Blackman, RK; Du, Z; Foley, KP; Inoue, T; Koya, K; Ogawa, LS; Proia, DA; Sang, J; Sun, L; Tatsuta, N; Wada, Y; Ye, S; Ying, W; Zhou, D1
Barsoum, J; Borgman, CL; Carey, CD; Carretero, J; Chen, L; Foley, KP; Inoue, T; Jimenez, JP; Li, D; Li, YC; Meyerson, M; Perera, SA; Rodig, SJ; Sang, J; Shapiro, GI; Shimamura, T; Sinha, P; Wong, KK; Ying, W1
Acquaviva, J; Friedland, JC; He, S; Proia, DA; Sang, J; Sequeira, M; Shafi, AA; Smith, DL; Wada, Y; Weigel, NL; Zhang, C1
Zhang, HJ; Zhang, L; Zhang, XT1
Bullova, P; Giubellino, A; Landau, M; Lee, MJ; Neckers, L; Pacak, K; Scroggins, B; Sourbier, C; Trepel, JB; Ying, W1
Chrysikos, D; Dimopoulos, MA; Papadimitriou, CA; Psaltopoulou, T; Sergentanis, TN; Zagouri, F1
Pillai, RN; Ramalingam, SS1
Jang, SW; Kim, J; Ko, J; Oh, M; Park, E; Park, S1
Bullinger, L; Döhner, H; Fröhling, S; Grasedieck, S; Kuchenbauer, F; Miller, C; Reinhart, S; Rouhi, A; Scholl, C; Stolze, B1
Fang, T; Lv, C; Nagle, DG; Wang, JX; Wu, T; Yang, PM; Yuan, X; Zeng, HW; Zhang, C; Zhang, WD; Zhou, YD1
Huang, LJ; Peng, Y; Peng, YC; Wang, S; Wang, XL; Zhang, Y1
Addi, L; Alfano, L; Baldassarre, G; Bruzzese, F; Budillon, A; Capone, F; Costa, A; Di Gennaro, E; Iannelli, F; Lombardi, R; Milone, MR; Moccia, T; Pucci, B; Roca, MS; Sonego, M1
Eshleman, JR; Gulla, A; Kazlauskas, E; Liang, H; Matulis, D; Petrauskas, V; Strupas, K1

Reviews

4 review(s) available for triazoles and tanespimycin

ArticleYear
[Management of metastatic HER2-positive breast cancer: present and future].
    Bulletin du cancer, 2010, Volume: 97, Issue:3

    Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Bevacizumab; Brain Neoplasms; Breast Neoplasms; Disease Progression; Female; Heart; Humans; Lactams, Macrocyclic; Lapatinib; Letrozole; Neoplasm Proteins; Nitriles; Quinazolines; Quinolines; Receptor, ErbB-2; Trastuzumab; Triazoles

2010
[Mechanisms of resistance to crizotinib in patients with transforming EML4-ALK fusion gene].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2012, Volume: 41, Issue:12

    Topics: Apoptosis; Benzoquinones; Carcinoma, Non-Small-Cell Lung; Crizotinib; Drug Resistance, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lung Neoplasms; Mutation; Oncogene Proteins, Fusion; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Triazoles

2012
Hsp90 inhibitors in breast cancer: a systematic review.
    Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:5

    Topics: Adenine; Antineoplastic Agents; Benzamides; Benzoquinones; Biomarkers, Tumor; Female; Glycine; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Indazoles; Isoxazoles; Lactams, Macrocyclic; Pyridines; Resorcinols; Triazoles; Triple Negative Breast Neoplasms

2013
Heat shock protein 90 inhibitors in non-small-cell lung cancer.
    Current opinion in oncology, 2014, Volume: 26, Issue:2

    Topics: Benzamides; Benzoquinones; Carcinoma, Non-Small-Cell Lung; HSP90 Heat-Shock Proteins; Humans; Isoindoles; Isoxazoles; Lactams, Macrocyclic; Lung Neoplasms; Molecular Targeted Therapy; Resorcinols; Treatment Outcome; Triazoles

2014

Other Studies

12 other study(ies) available for triazoles and tanespimycin

ArticleYear
Potent triazolothione inhibitor of heat-shock protein-90.
    Chemical biology & drug design, 2009, Volume: 74, Issue:1

    Topics: Animals; Benzoquinones; Cell Line, Tumor; Computer Simulation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; HSP90 Heat-Shock Proteins; HT29 Cells; Humans; Lactams, Macrocyclic; Mice; Mice, Nude; Transplantation, Heterologous; Triazoles; Xenograft Model Antitumor Assays

2009
Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias.
    Blood, 2010, Nov-25, Volume: 116, Issue:22

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Cell Line, Tumor; Etoposide; Female; Gene Expression Regulation, Leukemic; Gene Silencing; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia, Myeloid; Mice; Mice, SCID; Proteasome Endopeptidase Complex; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Triazoles; WT1 Proteins

2010
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Blotting, Western; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Crystallography, X-Ray; Female; Heart; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Lactams, Macrocyclic; Male; Mice; Mice, Nude; Mice, SCID; Neoplasms; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles; Xenograft Model Antitumor Assays

2012
Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Sep-15, Volume: 18, Issue:18

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; HSP90 Heat-Shock Proteins; Humans; Intramolecular Oxidoreductases; Lactams, Macrocyclic; Lung Neoplasms; Mice; Mice, SCID; Prostaglandin-E Synthases; Protein Binding; Protein Stability; Triazoles; Xenograft Model Antitumor Assays

2012
Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression.
    International journal of oncology, 2013, Volume: 42, Issue:1

    Topics: Animals; Apoptosis; Benzoquinones; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Flow Cytometry; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Male; Mice; Mice, SCID; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2013
Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Animals; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Female; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasm Metastasis; Pheochromocytoma; Rats; Triazoles

2013
The role of heat shock protein 90 in migration and proliferation of vascular smooth muscle cells in the development of atherosclerosis.
    Journal of molecular and cellular cardiology, 2014, Volume: 72

    Topics: Animals; Aorta; Atherosclerosis; Benzoquinones; Cell Cycle Checkpoints; Cell Line; Cell Movement; Cell Proliferation; Cholesterol; Diet, High-Fat; Gene Expression Regulation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Plaque, Atherosclerotic; Primary Cell Culture; Receptors, LDL; Signal Transduction; Triazoles

2014
Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Benzodioxoles; Benzoquinones; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Amplification; Genetic Predisposition to Disease; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mutation; Mutation, Missense; Neoplasms; Phenotype; Proto-Oncogene Proteins p21(ras); Purines; RNA Interference; Transfection; Triazoles

2017
The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG.
    Cell death & disease, 2018, 02-07, Volume: 9, Issue:2

    Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Benzoquinones; Biological Products; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; MAP Kinase Signaling System; MCF-7 Cells; Mice, Nude; Phosphatidylinositol 3-Kinases; Protein Kinase C; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Triazoles; Xenograft Model Antitumor Assays

2018
Hsp90β inhibitors prevent GLT-1 degradation but have no beneficial efficacy on absence epilepsy.
    Journal of Asian natural products research, 2019, Volume: 21, Issue:9

    Topics: Animals; Anticonvulsants; Benzoquinones; Epilepsy, Absence; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Mice; Pentylenetetrazole; Triazoles

2019
HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer.
    Molecular oncology, 2021, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Female; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Ovarian Neoplasms; Platinum; Proteomics; Triazoles; Xenograft Model Antitumor Assays

2021
Heat Shock Protein 90 Inhibitor Effects on Pancreatic Cancer Cell Cultures.
    Pancreas, 2021, 04-01, Volume: 50, Issue:4

    Topics: Adenosine Triphosphatases; Antineoplastic Agents; Benzamides; Benzoquinones; Carcinoma, Pancreatic Ductal; Cell Culture Techniques, Three Dimensional; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; HSP90 Heat-Shock Proteins; Humans; Isoindoles; Isoxazoles; Lactams, Macrocyclic; Molecular Structure; Pancreatic Neoplasms; Resorcinols; Rifabutin; Triazoles

2021