triazoles has been researched along with tacrine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Baraldi, PG; Fenu, S; Morelli, M; Simola, N; Tabrizi, MA | 2 |
| Kolb, HC; Krasiński, A; Manetsch, R; Radić, Z; Raushel, J; Sharpless, KB; Taylor, P | 1 |
| Cheng, Y; McCammon, JA; Senapati, S | 1 |
| Borsini, F; Carminati, P; Frau, L; Morelli, M; Schintu, N; Simola, N; Tronci, E | 1 |
| Jalali, A; Kawa, K; Larsen, C; Trevitt, J | 1 |
| Hao, GF; Yang, GF; Yang, WC; Yu, NX; Zhu, XL | 1 |
| Akbarzadeh, T; Asatouri, R; Karimpour-Razkenari, E; Khanavi, M; Mahdavi, M; Moghadam, FH; Najafi, Z; Saeedi, M; Sharifzadeh, M; Vafadarnejad, F | 1 |
| Akbarzadeh, T; Edraki, N; Karimpour-Razkenari, E; Khanavi, M; Mahdavi, M; Najafi, Z; Saeedi, M; Sharifzadeh, M | 1 |
| Bhatti, R; Gumede, N; Kaur, J; Kisten, P; Kumar, V; Rani, A; Singh, A; Singh, G; Singh, P | 1 |
| Ahmed, A; Bhagat, K; Choudhary, S; Kaur Gulati, H; Kumar, A; Kumar, N; Mukherjee, D; Singh Bedi, PM; Singh, A; Singh, H; Vir Singh, J | 1 |
11 other study(ies) available for triazoles and tacrine
| Article | Year |
|---|---|
Blockade of adenosine A2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on specific striatal regions.
Topics: Adenosine A2 Receptor Antagonists; Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Jaw; Male; Movement; Parkinsonian Disorders; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Tacrine; Time Factors; Trema; Triazoles | 2004 |
In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors.
Topics: Animals; Binding Sites; Cholinesterase Inhibitors; Combinatorial Chemistry Techniques; Mice; Phenanthridines; Stereoisomerism; Tacrine; Triazoles | 2005 |
Dopamine and adenosine receptor interaction as basis for the treatment of Parkinson's disease.
Topics: Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Jaw; Male; Movement; Parkinson Disease; Pilocarpine; Piperazines; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Tacrine; Tremor; Triazoles | 2006 |
In-situ synthesis of a tacrine-triazole-based inhibitor of acetylcholinesterase: configurational selection imposed by steric interactions.
Topics: Acetylcholinesterase; Acetylene; Azides; Binding Sites; Cholinesterase Inhibitors; Models, Molecular; Molecular Conformation; Quantum Theory; Tacrine; Triazoles | 2006 |
Characterization of the antiparkinsonian effects of the new adenosine A2A receptor antagonist ST1535: acute and subchronic studies in rats.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Dynorphins; Enkephalins; Glutamate Decarboxylase; Isoenzymes; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tacrine; Tremor; Triazoles | 2007 |
Differential effects of adenosine antagonists in two models of parkinsonian tremor.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Synergism; Jaw; Male; Parkinsonian Disorders; Pimozide; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Tacrine; Theophylline; Tremor; Triazoles | 2009 |
Structural basis of femtomolar inhibitors for acetylcholinesterase subtype selectivity: insights from computational simulations.
Topics: Acetylcholinesterase; Acridines; Animals; Binding Sites; Cholinesterase Inhibitors; Drosophila melanogaster; Isoenzymes; Mice; Molecular Dynamics Simulation; Phenanthridines; Protein Binding; Structure-Activity Relationship; Tacrine; Thermodynamics; Torpedo; Triazoles | 2013 |
Novel tacrine-1,2,3-triazole hybrids: In vitro, in vivo biological evaluation and docking study of cholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cell Death; Cell Line; Cell Line, Tumor; Cholinesterase Inhibitors; Humans; Kinetics; Male; Memory Disorders; Molecular Docking Simulation; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Structure-Activity Relationship; Tacrine; Triazoles | 2017 |
Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer's compounds: In vitro and in vivo biological evaluation and docking study.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Cholinesterase Inhibitors; Coumarins; Humans; Male; Maze Learning; Molecular Docking Simulation; Molecular Structure; Neuroprotective Agents; Nootropic Agents; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Tacrine; Torpedo; Triazoles | 2019 |
1H-1,2,3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice brain cells.
Topics: Acetylcholinesterase; Animals; Anxiety; Brain; Butyrylcholinesterase; Chalcones; Cholinesterase Inhibitors; Depression; Dose-Response Relationship, Drug; Mice; Molecular Docking Simulation; Molecular Structure; Oxidative Stress; Rats; Structure-Activity Relationship; Tacrine; Triazoles | 2021 |
Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity.
Topics: Acetylcholinesterase; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Glycoconjugates; Hep G2 Cells; Humans; Molecular Structure; Structure-Activity Relationship; Tacrine; Triazoles | 2022 |