Page last updated: 2024-08-24

triazoles and sm 8668

triazoles has been researched along with sm 8668 in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (10.91)	18.7374
1990's	48 (87.27)	18.2507
2000's	1 (1.82)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrade, J; Armstrong, D; Edwards, F; Niki, Y; Schmitt, HJ	1
Bava, AJ; Negroni, R	1
Anaissie, E; Bodey, G; Gokaslan, A; Griffin, G; Hachem, R; Robinson, R; Rubin, R; Sobel, J	1
Allendoerfer, R; Graybill, JR; Sun, SH; Yates, RR	1
Graybill, JR; Hardin, TC; Lam, YF; Rinaldi, MG; Sharkey, PK; Wallace, JE	1
Das, PR; DiBenedetto, DJ; Gala, D; Kugelman, M; Puar, MS	1
Foleno, B; Fu, KP; Isaacson, D; LoCoco, J	1
Chambers, HF; Lee, BL; Padula, AM; Sande, MA; Täuber, MG	1
Allendoerfer, R; Graybill, JR; Loebenberg, D; Marquis, AJ; Rinaldi, MG; Yates, RR	1
Antonacci, B; Cacciapuoti, A; Hare, RS; Loebenberg, D; Menzel, F; Miller, GH; Moss, EL; Norris, C; Parmegiani, R; Yarosh-Tomaine, T	2
Carlström, K; Lunell, NO; Pschera, H; Zador, G	1
Andriole, VT; George, D; Ingersoll, R; Miniter, P; Patterson, TF	1
Agorio, I; Costa, MR; Finquelievich, JL; Iovannitti, C; Loebenberg, D; Negroni, R; Tiraboschi, IN	1
Sugar, AM	1
Albert, MM; Graybill, JR; Rinaldi, MG	1
Graybill, JR; Sharkey, PK	1
Brummer, E; Hanson, LH; Stevens, DA	2
Defaveri, J; Graybill, JR; Sun, SH	1
Defaveri, J; Graybill, JR	1
Defaveri, J; Graybill, JR; Rinaldi, MG; Salazar, MH	1
Ichise, K; Nakajima, T; Okuda, T; Tanio, T	1
Bacher, J; Kelly, P; Lecciones, J; Lee, JW; Peter, J; Pizzo, PA; Thomas, V; Walsh, TJ	1
Lambert, C; Meunier, F; Van der Auwera, P	1
Kobayashi, GS; Medoff, G; Rinaldi, MG; Travis, SJ	1
Noble, L; Picard, M; Sugar, AM	1
Clemons, KV; Hanson, LH; Perlman, AM; Stevens, DA	1
Affrime, MB; Kosoglou, T; Lin, CC; Mojaverian, P; Perentesis, GP; Radwanski, E; Vlasses, PH	1
Balis, FM; Lee, JW; Lester-McCully, C; Pizzo, PA; Poplack, DG; Rinaldi, MG; Wallace, JE; Walsh, TJ	1
Graybill, JR	1
Galgiani, JN; McIntyre, KA	1
Ahrens, J; Graybill, JR; Restrepo, BI	1
Durack, DT; Hobbs, MM; Perfect, JR; Wright, KA	1
Lee, JW; Lin, C; Loebenberg, D; Pizzo, PA; Rubin, M; Walsh, TJ	1
Dismukes, WE	1
Allendoerfer, R; Graybill, JR; Loebenberg, D; Rinaldi, MG	1
Staben, C	1
Affrime, MB; Cayen, MN; Lin, CC; Mojaverian, P; Radwanski, E	1
Bartlett, MS; Queener, SF; Richardson, JD; Shaw, MM; Smith, JW	1
Kim, H; Lapiguera, A; Lin, C	1
al-Haidary, AD; Catanzaro, A; Cloud, GA; Graybill, JR; Hostetler, JS; Larsen, RA; Rinaldi, MG; Sharkey, PK; Stevens, DA; Tucker, RM	1
Anaissie, EJ; Andersson, BS; Bodey, GP; Champlin, RE; Giralt, SA; Kantarjian, HM; Karl, C; Kontoyiannis, DP; O'Brien, S; Vartivarian, S	1
Goldani, LZ; Sugar, AM	1
Antonacci, B; Cacciapuoti, A; Hare, RS; Loebenberg, D; Menzel, F; Miller, GH; Moss, L; Norris, C; Parmegiani, RM; Yarosh-Tomaine, T	1
Klopman, G; Ptchelintsev, D	1
Brummer, E; Coffman, RL; Hostetler, JS; Stevens, DA	1
Antonacci, B; Assenza, S; Cacciapuoti, A; Chaudry, I; Eckhart, C; Levine, N; Loebenberg, D; Norris, C; Parmegiani, R; Wearley, L	1
Kim, H; Lin, CC	1
Affrime, M; Brannan, M; Cayen, MN; Kim, H; Lin, C; Radwanski, E	1
Kozuki, K; Miyauchi, H; Ohashi, N; Tanio, T	1
Baldwin, BC; Boscott, P; Gozzo, F; Kelly, DE; Kelly, SL; Lamb, DC; Richards, WG	1
Kelly, SL; Venkateswarlu, K	1
Baldwin, BC; Kelly, SL; Kwon-Chung, KJ; Lamb, DC	1
Kim, H; Lin, CC; Lovey, R; Nomeir, AA; Radwanski, E	1

Reviews

3 review(s) available for triazoles and sm 8668

Article	Year
Fungal infections and their management. British journal of clinical practice. Supplement, 1990, Volume: 71 Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses; Naphthalenes; Terbinafine; Triazoles	1990
New antifungal agents. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Azoles; Echinocandins; Fluconazole; Fungi; Humans; Itraconazole; Ketoconazole; Mycoses; Peptides; Peptides, Cyclic; Triazoles	1989
Azole antifungal drugs: old and new. Annals of internal medicine, 1988, Aug-01, Volume: 109, Issue:3 Topics: Animals; Antifungal Agents; Azoles; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Triazoles	1988

Trials

5 trial(s) available for triazoles and sm 8668

Article	Year
The effect of antacid and cimetidine on the oral absorption of the antifungal agent SCH 39304. Journal of clinical pharmacology, 1990, Volume: 30, Issue:7 Topics: Absorption; Administration, Oral; Adult; Antacids; Antifungal Agents; Biological Availability; Cimetidine; Drug Administration Schedule; Drug Interactions; Humans; Male; Random Allocation; Time Factors; Triazoles	1990
Pharmacokinetics of the triazole antifungal agent genaconazole in healthy men after oral and intravenous administration. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:12 Topics: Administration, Oral; Adult; Antifungal Agents; Cross-Over Studies; Humans; Injections, Intravenous; Male; Triazoles	1994
Treatment of coccidioidomycosis with SCH 39304. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1994, Volume: 32, Issue:2 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antifungal Agents; Coccidioidomycosis; Dermatomycoses; Drug Administration Schedule; Female; HIV Infections; Humans; Joint Diseases; Lung Diseases, Fungal; Male; Middle Aged; Treatment Outcome; Triazoles	1994
Effectiveness of an oral triazole for opportunistic mold infections in patients with cancer: experience with SCH 39304. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 17, Issue:6 Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Female; Humans; Leukemia; Male; Middle Aged; Mycoses; Neoplasms; Opportunistic Infections; Prospective Studies; Triazoles	1993
Pharmacokinetics and metabolism of genaconazole, a potent antifungal drug, in men. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Cross-Over Studies; Double-Blind Method; Feces; Half-Life; Humans; Male; Stereoisomerism; Triazoles	1996

Other Studies

47 other study(ies) available for triazoles and sm 8668

Article	Year
Comparison of azoles against aspergilli in vitro and in an experimental model of pulmonary aspergillosis. Chemotherapy, 1992, Volume: 38, Issue:2 Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Disease Models, Animal; Itraconazole; Ketoconazole; Male; Rats; Rats, Inbred Strains; Triazoles	1992
Comparative study of six antifungal treatments in an experimental model of murine cryptococcosis. European journal of epidemiology, 1992, Volume: 8, Issue:3 Topics: Amphotericin B; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Mice; Mice, Inbred BALB C; Triazoles	1992
Azole therapy for trichosporonosis: clinical evaluation of eight patients, experimental therapy for murine infection, and review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 15, Issue:5 Topics: Adult; Aged; Amphotericin B; Animals; Antifungal Agents; Child, Preschool; Disease Models, Animal; Female; Fluconazole; Humans; Immunocompromised Host; Male; Mice; Miconazole; Middle Aged; Mycoses; Triazoles; Trichosporon	1992
Comparison of amphotericin B lipid complex with amphotericin B and SCH 39304 in the treatment of murine coccidioidal meningitis. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1992, Volume: 30, Issue:5 Topics: Amphotericin B; Animals; Antifungal Agents; Coccidioidomycosis; Drug Carriers; Liposomes; Meningitis, Fungal; Mice; Triazoles	1992
Pharmacokinetics of SCH-39304 in human immunodeficiency virus-infected patients following chronic oral dosing. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:12 Topics: Administration, Oral; Adult; Antifungal Agents; Candidiasis, Oral; Drug Administration Schedule; HIV Infections; HIV-1; Humans; Male; Middle Aged; Triazoles	1992
Decomposition of alpha-hydroxyaryl ketones and characterization of some unusual products. Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:12 Topics: Antifungal Agents; Benzene; Chromatography, Thin Layer; Drug Stability; Fluorobenzenes; Ketones; Oxidation-Reduction; Triazoles	1992
Saperconazole: in vitro and in vivo anticandidal activity. Chemotherapy, 1992, Volume: 38, Issue:3 Topics: Amphotericin B; Antifungal Agents; Azoles; Candida; Drug Synergism; Fluconazole; Microbial Sensitivity Tests; Species Specificity; Triazoles	1992
Oral SCH 39304 as primary, salvage, and maintenance therapy for cryptococcal meningitis in AIDS. Journal of acquired immune deficiency syndromes, 1992, Volume: 5, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Antifungal Agents; Follow-Up Studies; Humans; Male; Meningitis, Cryptococcal; Middle Aged; Prospective Studies; Triazoles; Zidovudine	1992
Comparison of SCH 39304 and its isomers, RR 42427 and SS 42426, for treatment of murine cryptococcal and coccidioidal meningitis. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1 Topics: Administration, Oral; Animals; Antifungal Agents; Azoles; Coccidioides; Coccidioidomycosis; Cryptococcus neoformans; Culture Techniques; Isomerism; Meningitis, Cryptococcal; Mice; Triazoles	1992
Comparison of SCH 39304, fluconazole, and ketoconazole for treatment of systemic infections in mice. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1 Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Drug Evaluation, Preclinical; Fluconazole; Injections, Intravenous; Ketoconazole; Kidney; Male; Mice; Triazoles	1992
In vitro and in vivo activities of SCH 42427, the active enantiomer of the antifungal agent SCH 39304. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:2 Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus flavus; Candidiasis; Candidiasis, Vulvovaginal; Cricetinae; Dermatomycoses; Female; Fungi; Guinea Pigs; Male; Mesocricetus; Mice; Microbial Sensitivity Tests; Rats; Rats, Inbred Strains; Stereoisomerism; Triazoles; Trichophyton	1992
Evaluation of the possible interaction of the antifungal triazole SCH 39304 with oral contraceptives in normal healthy women. Gynecologic and obstetric investigation, 1991, Volume: 32, Issue:2 Topics: Adult; Antifungal Agents; Contraceptives, Oral, Combined; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Estradiol; Female; Humans; Hydrocortisone; Progesterone; Sex Hormone-Binding Globulin; Triazoles	1991
Efficacy of SCH 39304 in treatment of experimental invasive aspergillosis. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:10 Topics: Amphotericin B; Animals; Antifungal Agents; Antigens, Fungal; Aspergillosis; Enzyme-Linked Immunosorbent Assay; Immunosuppression Therapy; Leukopenia; Rabbits; Triazoles	1991
Treatment of experimental cryptococcosis with SCH 39304 and fluconazole. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:7 Topics: Animals; Antifungal Agents; Brain; Cryptococcosis; Female; Fluconazole; Lung; Male; Rats; Rats, Inbred Strains; Triazoles	1991
Interactions of amphotericin B and SCH 39304 in the treatment of experimental murine candidiasis: lack of antagonism of a polyene-azole combination. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:8 Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Female; Kidney; Mice; Mice, Inbred ICR; Triazoles	1991
Treatment of murine cryptococcal meningitis with an SCH 39304-amphotericin B combination. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:9 Topics: Amphotericin B; Animals; Body Burden; Brain; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Therapy, Combination; Meningitis, Cryptococcal; Mice; Mice, Inbred BALB C; Neisseria meningitidis; Triazoles	1991
SCH 39304 in the treatment of acute or established murine pulmonary blastomycosis. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4 Topics: Animals; Antifungal Agents; Blastomycosis; Fluconazole; Ketoconazole; Lung Diseases; Mice; Mice, Inbred BALB C; Triazoles	1991
Treatment of murine coccidioidal meningitis with SCH39304. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:4 Topics: Animals; Antifungal Agents; Coccidioidomycosis; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluconazole; Itraconazole; Ketoconazole; Meningitis; Mice; Mice, Inbred BALB C; Triazoles	1990
Treatment of chronic murine chromoblastomycosis with the triazole SCH39304. The American journal of tropical medicine and hygiene, 1990, Volume: 42, Issue:6 Topics: Animals; Antifungal Agents; Chromoblastomycosis; Chronic Disease; Disease Models, Animal; Female; Itraconazole; Ketoconazole; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron; Mitosporic Fungi; Skin; Triazoles	1990
Pulmonary aspergillosis in mice: treatment with a new triazole SCH39304. The American review of respiratory disease, 1990, Volume: 142, Issue:3 Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Female; Fluconazole; Lung Diseases, Fungal; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Triazoles	1990
In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6 Topics: Administration, Cutaneous; Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candidiasis, Vulvovaginal; Cryptococcosis; Female; Fluconazole; Guinea Pigs; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Tinea; Triazoles	1990
SCH-39304 in prevention and treatment of disseminated candidiasis in persistently granulocytopenic rabbits. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:8 Topics: Agranulocytosis; Amphotericin B; Animals; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Candidiasis; Disease Models, Animal; Female; Fluconazole; Immunosuppression Therapy; Rabbits; Triazoles	1990
In-vitro activity of SCH39304 in comparison with amphotericin B and fluconazole. The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:2 Topics: Amphotericin B; Culture Media; Fluconazole; Fungi; Humans; Microbial Sensitivity Tests; Triazoles	1990
In vitro and in vivo activities of Sch 39304, fluconazole, and amphotericin B against Histoplasma capsulatum. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:4 Topics: Amphotericin B; Animals; Antifungal Agents; Female; Fluconazole; Histoplasma; Histoplasmosis; Leukopenia; Mice; Microbial Sensitivity Tests; Triazoles	1990
Treatment of murine pulmonary blastomycosis with SCH 39304, a new triazole antifungal agent. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:5 Topics: Amphotericin B; Animals; Antifungal Agents; Blastomycosis; Fluconazole; Lung; Lung Diseases, Fungal; Male; Mice; Mice, Inbred BALB C; Triazoles	1990
Efficacy of SCH39304 and fluconazole in a murine model of disseminated coccidioidomycosis. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:5 Topics: Animals; Antifungal Agents; Coccidioidomycosis; Fluconazole; Male; Mice; Triazoles	1990
Penetration of SCH-39304, a new antifungal triazole, into cerebrospinal fluid of primates. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6 Topics: Animals; Antifungal Agents; Half-Life; Macaca mulatta; Male; Triazoles	1990
In vitro susceptibilities of yeasts to a new antifungal triazole, SCH 39304: effects of test conditions and relation to in vivo efficacy. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:7 Topics: Antifungal Agents; Buffers; Candida; Candida albicans; Culture Media; Fluconazole; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Temperature; Time Factors; Triazoles	1989
Efficacy of SCH39304 in murine cryptococcosis. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:8 Topics: Amphotericin B; Animals; Antifungal Agents; Brain; Cryptococcosis; Female; Fluconazole; Lung; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Spleen; Triazoles	1989
Treatment of experimental cryptococcal meningitis and disseminated candidiasis with SCH39304. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:10 Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Cryptococcosis; Cryptococcus neoformans; Fluconazole; Meningitis; Microbial Sensitivity Tests; Rabbits; Triazoles	1989
Pharmacokinetics and tissue penetration of Sch 39304 in granulocytopenic and nongranulocytopenic rabbits. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:11 Topics: Agranulocytosis; Animals; Antifungal Agents; Chromatography, Gas; Half-Life; Male; Rabbits; Tissue Distribution; Triazoles	1989
Evaluation of SCH51048 in an experimental model of pulmonary aspergillosis. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6 Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Evaluation; Female; Itraconazole; Lung Diseases, Fungal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Survival Rate; Triazoles	1995
Resistance to azole drugs in Neurospora crassa. Experimental mycology, 1995, Volume: 19, Issue:2 Topics: Antifungal Agents; Crosses, Genetic; Drug Resistance, Microbial; Fluconazole; Ketoconazole; Meiosis; Mutagenesis; Neurospora crassa; Selection, Genetic; Triazoles	1995
IL-4, IgE, and interferon-gamma production in pulmonary blastomycosis: comparison in mice untreated, immunized, or treated with an antifungal (SCH 39304). Cellular immunology, 1993, Volume: 149, Issue:2 Topics: Animals; Antifungal Agents; Antigens, Surface; Blastomycosis; Cells, Cultured; Disease Models, Animal; Immunization; Immunoglobulin E; Interferons; Interleukin-4; Lung; Lymph Nodes; Lymphocytes; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Spleen; Thy-1 Antigens; Triazoles	1993
Pneumocystis carinii is resistant to imidazole antifungal agents. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8 Topics: Animals; Antifungal Agents; Ergosterol; Female; Fluconazole; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Miconazole; Pneumocystis; Rats; Rats, Sprague-Dawley; Triazoles	1994
Gas chromatographic and high-performance liquid chromatographic methods for the determination of genaconazole in biological fluids. Journal of chromatography. B, Biomedical applications, 1994, Apr-22, Volume: 655, Issue:1 Topics: Antifungal Agents; Chromatography, Gas; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Triazoles	1994
Treatment of murine pulmonary mucormycosis with SCH 42427, a broad-spectrum triazole antifungal drug. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:2 Topics: Amphotericin B; Animals; Antifungal Agents; Lung Diseases, Fungal; Mice; Mice, Inbred ICR; Mucormycosis; Triazoles	1994
Sch 39304, a new antifungal agent: oral and topical treatment of vaginal and superficial infections. Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1993, Volume: 31, Issue:3 Topics: Administration, Oral; Administration, Topical; Animals; Antifungal Agents; Candidiasis, Vulvovaginal; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluconazole; Guinea Pigs; Miconazole; Tinea; Triazoles	1993
Antifungal triazole alcohols: a comparative analysis of structure-activity, structure-teratogenicity and structure-therapeutic index relationships using the Multiple Computer-Automated Structure Evaluation (Multi-CASE) methodology. Journal of computer-aided molecular design, 1993, Volume: 7, Issue:3 Topics: Animals; Antifungal Agents; Candida; Databases, Factual; Drug Design; Humans; Software; Structure-Activity Relationship; Teratogens; Triazoles	1993
Effect of anti-IL-4, interferon-gamma and an antifungal triazole (SCH 42427) in paracoccidioidomycosis: correlation of IgE levels with outcome. Clinical and experimental immunology, 1993, Volume: 94, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antifungal Agents; Chronic Disease; Immunoglobulin E; Interferon-gamma; Interleukin-4; Mice; Mice, Inbred BALB C; Paracoccidioidomycosis; T-Lymphocytes, Helper-Inducer; Triazoles	1993
Relationship among physicochemical properties, skin permeability, and topical activity of the racemic compound and pure enantiomers of a new antifungal. Pharmaceutical research, 1993, Volume: 10, Issue:1 Topics: Adult; Animals; Antifungal Agents; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Guinea Pigs; Humans; In Vitro Techniques; Male; Microbial Sensitivity Tests; Skin; Skin Absorption; Solubility; Stereoisomerism; Tinea; Triazoles; Trichophyton	1993
A chiral liquid chromatographic method for the determination of the enantiomers of the racemic triazole antifungal drug (SCH 39304) in human plasma. Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:11 Topics: Antifungal Agents; Chromatography, Liquid; Humans; Stereoisomerism; Triazoles	1995
Synthesis and antifungal activity of alkylthio and alkylsulfonyl derivatives of SM-8668. Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:2 Topics: Alkylation; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Mice; Structure-Activity Relationship; Sulfur; Triazoles	1996
Differential inhibition of Candida albicans CYP51 with azole antifungal stereoisomers. FEMS microbiology letters, 1997, Apr-01, Volume: 149, Issue:1 Topics: Antifungal Agents; Binding Sites; Candida albicans; Chlorobenzenes; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Fungal Proteins; Oxidoreductases; Stereoisomerism; Sterol 14-Demethylase; Triazoles	1997
Stereoselective interaction of SCH 39304, a triazole, with sterol 14alpha-demethylase of Aspergillus fumigatus. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:5 Topics: Antifungal Agents; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Ergosterol; Microbial Sensitivity Tests; Oxidoreductases; Stereoisomerism; Sterol 14-Demethylase; Triazoles	1997
Stereoselective interaction of the azole antifungal agent SCH39304 with the cytochrome P-450 monooxygenase system isolated from Cryptococcus neoformans. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:7 Topics: Antifungal Agents; Cryptococcus neoformans; Cytochrome P-450 Enzyme System; Ergosterol; Humans; Microbial Sensitivity Tests; Microsomes; Stereoisomerism; Triazoles	1997
Pharmacokinetics of the active antifungal enantiomer, SCH 42427 (RR), and evaluation of its chiral inversion in animals following its oral administration and the oral administration of its racemate genaconazole (RR/SS). Chirality, 2002, May-15, Volume: 14, Issue:5 Topics: Administration, Oral; Animals; Antifungal Agents; Biological Availability; Chromatography, High Pressure Liquid; Macaca fascicularis; Male; Rats; Stereoisomerism; Triazoles	2002