Compounds > triazoles
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triazoles and s 1360

triazoles has been researched along with s 1360 in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stephenson, J1
Billich, A1
De Clercq, E; De Maeyer, M; Debyser, Z; Engelborghs, Y; Fikkert, V; Gurnari, C; Hantson, A; Michiels, M; Pannecouque, C; Van Maele, B; Van Remoortel, B; Vercammen, J; Witvrouw, M1
Fujishita, T; Rosemond, MJ; St John-Williams, L; Walsh, JS; Yamaguchi, T1
Johnson, AA; Marchand, C; Pommier, Y1
Dayam, R; Neamati, N1
De Clercq, E; De Maeyer, M; Debyser, Z; Fikkert, V; Hombrouck, A; Pannecouque, C; Van Remoortel, B; Witvrouw, M1
Clement, O; Dayam, R; Neamati, N; Sanchez, T; Sei, S; Shoemaker, R1
Dayam, R; Neamati, N; Sanchez, T1
Wang, C; Zhao, GS1
Alves, CN; Andrés, J; Castillo, R; Martí, S; Moliner, V; Silla, E; Tuñón, I1
Al-Mawsawi, LQ; Dayam, R; Neamati, N1
Chen, JM; Chen, X; Hung, M; Jin, H; Jones, GS; Kim, CU; Qi, X; Swaminathan, S; Tsiang, M; Yu, F; Zeynalzadegan, A1
Foster, SA; Fujishita, T; Fujiwara, T; Garvey, EP; Johns, BA; Kanamori-Koyama, M; Kawauchi, S; Kobayashi, M; Miki, S; Nakahara, K; Noshi, T; Sato, A; Seki, T; Suyama, A; Underwood, MR; Wakasa-Morimoto, C; Yoshinaga, T1
Barreca, ML; Chimirri, A; De Luca, L; Iraci, N1

Reviews

3 review(s) available for triazoles and s 1360

ArticleYear
S-1360 Shionogi-GlaxoSmithKline.
    Current opinion in investigational drugs (London, England : 2000), 2003, Volume: 4, Issue:2

    Topics: Anti-HIV Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Furans; HIV Infections; HIV Integrase Inhibitors; Humans; Triazoles

2003
HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial.
    Current topics in medicinal chemistry, 2004, Volume: 4, Issue:10

    Topics: Acetoacetates; Anti-HIV Agents; Biological Factors; Caffeic Acids; Clinical Trials as Topic; Furans; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Indoles; Models, Molecular; Molecular Structure; Oligonucleotides; Pyrroles; Reverse Transcriptase Inhibitors; Succinates; Tetrazoles; Triazoles

2004
[Advances in the study of HIV-1 integrase inhibitor of aryl beta-diketoacids].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:9

    Topics: Animals; Anti-HIV Agents; Furans; HIV Integrase Inhibitors; HIV-1; Humans; Keto Acids; Molecular Structure; Naphthyridines; Triazoles

2006

Other Studies

12 other study(ies) available for triazoles and s 1360

ArticleYear
Researchers explore new anti-HIV agents.
    JAMA, 2002, Apr-03, Volume: 287, Issue:13

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclic N-Oxides; Drugs, Investigational; Enfuvirtide; Furans; HIV; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV Infections; HIV Integrase Inhibitors; Humans; Nitriles; Oximes; Peptide Fragments; Piperazines; Piperidines; Pyridazines; Pyridines; Pyrimidines; Reverse Transcriptase Inhibitors; Triazoles

2002
Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations.
    Journal of virology, 2003, Volume: 77, Issue:21

    Topics: Acetoacetates; Anti-HIV Agents; Cell Line; Drug Resistance, Viral; Furans; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Models, Molecular; Mutation; Recombination, Genetic; Triazoles; Virus Integration; Virus Replication

2003
Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor, S-1360: role of human liver cytosolic aldo-keto reductases.
    Chemico-biological interactions, 2004, Mar-15, Volume: 147, Issue:2

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Anti-HIV Agents; Carbon Radioisotopes; Cytosol; Enzyme Inhibitors; Furans; HIV Integrase Inhibitors; Humans; Liver; Microsomes, Liver; Mitochondria, Liver; Oxidation-Reduction; Triazoles

2004
Active site binding modes of the beta-diketoacids: a multi-active site approach in HIV-1 integrase inhibitor design.
    Bioorganic & medicinal chemistry, 2004, Dec-15, Volume: 12, Issue:24

    Topics: Anti-HIV Agents; Binding Sites; Carboxylic Acids; Computer Simulation; Drug Design; Drug Resistance; Furans; HIV Integrase; HIV Integrase Inhibitors; Molecular Conformation; Protein Binding; Protein Conformation; Structure-Activity Relationship; Triazoles

2004
Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.
    AIDS (London, England), 2004, Oct-21, Volume: 18, Issue:15

    Topics: Anti-HIV Agents; Cells, Cultured; Clone Cells; Drug Resistance, Viral; Furans; HIV Infections; HIV Integrase; HIV-1; Humans; Mutation; Phenotype; Polymerase Chain Reaction; Triazoles; Virus Replication

2004
Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
    Journal of medicinal chemistry, 2005, Jan-13, Volume: 48, Issue:1

    Topics: Anti-HIV Agents; Cells, Cultured; Drug Design; Drug Evaluation, Preclinical; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Models, Molecular; Molecular Structure; Rhodanine; Salicylic Acid; Structure-Activity Relationship; T-Lymphocytes; Triazoles

2005
Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
    Journal of medicinal chemistry, 2005, Dec-15, Volume: 48, Issue:25

    Topics: Cell Line; Databases, Factual; Drug Design; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Hydrogen Bonding; Keto Acids; Models, Molecular; Structure-Activity Relationship; Triazoles

2005
Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Amino Acid Sequence; Amino Acid Substitution; Crystallography, X-Ray; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Lysine; Magnesium; Models, Chemical; Propane; Protein Conformation; Pyrroles; Structure-Activity Relationship; Triazoles

2007
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase.
    Bioorganic & medicinal chemistry letters, 2007, Nov-15, Volume: 17, Issue:22

    Topics: Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Molecular Structure; Organic Chemicals; Pyrroles; Pyrrolidinones; Quinolones; Raltegravir Potassium; Triazoles

2007
Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors.
    Journal of molecular biology, 2008, Jul-11, Volume: 380, Issue:3

    Topics: Acetoacetates; Binding Sites; Crystallography, X-Ray; DNA, Viral; Furans; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Hydrophobic and Hydrophilic Interactions; Magnesium; Models, Chemical; Models, Molecular; Mutation; Naphthyridines; Nucleic Acid Conformation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrroles; Reproducibility of Results; Triazoles

2008
Secondary mutations in viruses resistant to HIV-1 integrase inhibitors that restore viral infectivity and replication kinetics.
    Antiviral research, 2009, Volume: 81, Issue:2

    Topics: Anti-HIV Agents; Furans; HIV Integrase; HIV-1; Humans; Jurkat Cells; Mutation, Missense; Triazoles; Virus Replication

2009
Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors.
    ChemMedChem, 2009, Volume: 4, Issue:9

    Topics: Acetoacetates; Anti-HIV Agents; Binding Sites; Computer Simulation; Drug Design; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Mutation; Naphthyridines; Pyrroles; Pyrrolidinones; Quinolones; Raltegravir Potassium; Triazoles

2009