Compounds > triazoles
Page last updated: 2024-08-24

triazoles and ribavirin

triazoles has been researched along with ribavirin in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19908 (22.22)18.7374
1990's0 (0.00)18.2507
2000's12 (33.33)29.6817
2010's14 (38.89)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Miller, JP; Robins, RK; Simon, LN; Streeter, DG1
Bisagni, E; Civier, A; Huynh-Dinh, T; Igolen, J; Marquet, JP1
Borghi, C; Del Puppo, M; Galli Kienle, M; Paroni, R; Sirtori, CR1
Gurskaia, GV; Lindeman, SV; Struchkov, IuT; Tsapkina, EN; Zavgorodniĭ, SG1
Gottikh, BP; Gurskaia, GV; Tsapkina, EN; Tsilevich, TL; Zavgorodniĭ, SG1
Gurskaia, GV; Lindeman, SV; Struchkov, IuT; Tsapkina, EN; Tsilevich, TL1
Bieser, W; Fiebig, HH; Henss, H; Lohr, GW; Schmid, JR1
Borghi, C; Kienle, MG; Paroni, R; Sirtori, CR1
Busson, R; De Clercq, E; Herdewijn, P; Neyts, J; Rozenski, J; Schepers, G; Van Aerschot, A1
An, GI; Rhee, H1
Chun, MW; Jeong, LS; Kim, BR; Kim, JH; Kim, MJ1
Peng, L; Qu, F; Wan, J; Wu, Q; Xia, Y1
Arterburn, JB; Chung, K; Jeselnik, M; Jonsson, CB; Kumarapperuma, SC; Parker, WB; Sun, Y1
Herrmann, E; Hofmann, WP; Kronenberger, B; Lohmann, V; Mihm, U; Polta, A; Sarrazin, C; Schönberger, B; Sonntag, T; Zeuzem, S1
Berg, T; Bergk, A; Krüger, D; Plöckinger, U; Weich, V; Wiedenmann, B1
Caamaño, O; De Clercq, E; Fernández, F; García, MD; López, C; Pérez-Castro, I1
Arterburn, JB; Chu, YK; Chung, DH; Jonsson, CB; Kumarapperuma, SC; Li, Q; Parker, WB; Ramanathan, HN; Schmaljohn, CS; Smith, J; Spik, K; Sun, Y1
Baltaze, JP; Dos Santos, M; Lubin-Germain, N; Roussel, S; Uziel, J; Youcef, RA1
Abderrahim, E; Ben Abdallah, T; Ben Hamida, F; Ben Maïz, H; Bezzine, H; Hedri, H; Khaled, S; Kheder, A; Ounissi, M; Trabelsi, S1
Arterburn, JB; Gonzales, SR; Hanley, KA; Jeselnik, M; Kumarapperuma, SC; McDowell, M1
Singh, V; Somvanshi, P1
Hammond, JL; Jagannatha, S; Kantaridis, C; Neelakantan, S; Purohit, VS; Simpson, P; Thompson, R; Troke, PJ; Wagner, F1
Cai, J; Cen, P; Huang, L; Liu, Y; Luo, W; Xu, Z; Zhao, W; Zhu, X1
Danilenko, DM; Deeva, EG; Eropkin, MIu; Kiselev, OI; Smirnova, TD1
Appleby, TC; Bidgood, AM; Byun, D; Canales, E; Clarke, MO; Doerffler, E; Eng, S; Fenaux, M; Hashash, A; Krawczyk, SH; Lazerwith, SE; Leavitt, SA; Lee, YJ; Lew, W; Liu, Q; Mabery, EM; Matles, M; Mertzman, M; Morganelli, P; Murray, BP; Mwangi, J; Tian, Y; Watkins, WJ; Xu, L; Ye, H; Zhang, J1
Day, CW; Hurst, BL; Januszczyk, P; Krajczyk, A; Kulinska, K; Kulinski, T; Ostrowski, T; Smee, DF; Zeidler, J1
Balzarini, J; Głowacka, IE; Wróblewski, AE1
Borisevich, SV; Charushin, VN; Chupakhin, ON; Loginova, SIa; Rusinov, VL; Ulomskiĭ, UN1
Borisevich, SV; Charushin, VN; Chupakhin, ON; Loginova, SY; Rusinov, VL; Sorokin, PV; Ulomsky, EN1
Byun, JK; Choi, YK; Jang, SY; Jeon, JH; Jung, GS; Kang, YN; Kim, MK; Kim, SW; Lee, IK; Lee, S; Park, KG; Park, SY; Shin, EC1
Abu-Zaied, MA; Elgemeie, GH; Nawwar, GA1
Berezovskaya, YV; Chudinov, MV; Grebenkina, LE; Matveev, AV; Prutkov, AN1
Li, N; Niu, F; Zhang, C1
Brocato, RL; Hooper, JW1
Chudinov, MV; Grebenkina, LE; Matveev, AV; Prutkov, AN1
Chandra, S; Roh, J; Thomas, AA; Venteicher, B; Way, H1

Reviews

1 review(s) available for triazoles and ribavirin

ArticleYear
Progress on the Prevention and Treatment of Hantavirus Disease.
    Viruses, 2019, 07-04, Volume: 11, Issue:7

    Topics: Adrenal Cortex Hormones; Amides; Animals; Antiviral Agents; Clinical Trials as Topic; Hantavirus Infections; Hantavirus Pulmonary Syndrome; Hemorrhagic Fever with Renal Syndrome; Humans; Immunotherapy; Lactoferrin; Models, Animal; Nucleosides; Orthohantavirus; Piperidines; Pyrazines; Quinazolines; Recombinant Proteins; Ribavirin; Triazoles; Vaccines, Synthetic; Viral Vaccines

2019

Trials

2 trial(s) available for triazoles and ribavirin

ArticleYear
Antiviral activity of the hepatitis C virus polymerase inhibitor filibuvir in genotype 1-infected patients.
    Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:1

    Topics: Adult; Antiviral Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Pyrones; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome; Triazoles; Viral Nonstructural Proteins

2011
Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Animals; Antiviral Agents; Cell Line, Tumor; Dogs; Drug Resistance, Viral; Furans; Hepacivirus; Humans; Interferon-alpha; Male; Mutation; Polymorphism, Single Nucleotide; Pyrones; Rats; Rats, Sprague-Dawley; Ribavirin; RNA-Dependent RNA Polymerase; Thiophenes; Triazoles; Viral Nonstructural Proteins

2013

Other Studies

33 other study(ies) available for triazoles and ribavirin

ArticleYear
The enzymic conversion of 1,2,4-triazole-3-carboxamide to ribavirin-5'-phosphate and its relationship to the proposed mechanism of action.
    Annals of the New York Academy of Sciences, 1977, Mar-04, Volume: 284

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cattle; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Mice; Nucleosides; Nucleotides; Organophosphorus Compounds; Phosphotransferases; Purine-Nucleoside Phosphorylase; Rats; Ribavirin; Ribonucleosides; Triazoles

1977
Synthesis of C-nucleosides. Part 14. 5(3)-Glycosyl-1,2,4-triazole-3(5)-carboxamides as analogues of ribavirin.
    Journal of the Chemical Society. Perkin transactions 1, 1977, Issue:7

    Topics: Magnetic Resonance Spectroscopy; Mass Spectrometry; Nucleosides; Ribavirin; Triazoles

1977
Pharmacokinetics of ribavirin and urinary excretion of the major metabolite 1,2,4-triazole-3-carboxamide in normal volunteers.
    International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:6

    Topics: Adult; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Ribavirin; Ribonucleosides; Triazoles

1989
[The structure and antiviral activity of ribavirin analogs. II. Molecular and crystal structure of 1-(1,5-dihydroxy-3-oxapent-2-yl)-1,2,4-triazole-5-carboxamide].
    Bioorganicheskaia khimiia, 1988, Volume: 14, Issue:8

    Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Crystallization; Models, Molecular; Molecular Conformation; Ribavirin; Simplexvirus; Triazoles

1988
[The structure and antiviral activity of ribavirin analogs. I. Molecular and crystal structure of 1-(2-hydroxyethoxymethyl)-1,2,4-triazole-5-carboxamide].
    Bioorganicheskaia khimiia, 1988, Volume: 14, Issue:8

    Topics: Acyclovir; Antiviral Agents; Chemical Phenomena; Chemistry; Crystallization; Models, Molecular; Molecular Conformation; Ribavirin; Triazoles

1988
[The structure and antiviral activity of ribavirin analogs. III. Molecular and crystal structure of 1-(2-hydroxyethoxymethyl)-1,2,4-triazole-carboxamide].
    Bioorganicheskaia khimiia, 1988, Volume: 14, Issue:8

    Topics: Antiviral Agents; Crystallization; Models, Molecular; Molecular Conformation; Ribavirin; Triazoles

1988
Colony assay with human tumor xenografts, murine tumors and human bone marrow. Potential for anticancer drug development.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:7

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Division; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Nude; Neoplasms, Experimental; Ribavirin; Transplantation, Heterologous; Triazoles

1987
High-performance liquid chromatographic determination of ribavirin in serum and urine and of its urinary metabolite 1,2,4-triazole-3-carboxamide.
    Journal of chromatography, 1987, Sep-04, Volume: 420, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Hydrolysis; Ribavirin; Ribonucleosides; Triazoles

1987
Ribavirin derivatives with a hexitol moiety: synthesis and antiviral evaluation.
    Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:1

    Topics: Antiviral Agents; Cell Line; Diarrhea Viruses, Bovine Viral; Herpesviridae; Microbial Sensitivity Tests; Models, Chemical; Ribavirin; Sugar Alcohols; Triazoles; Yellow fever virus

2003
Synthesis of carbocyclic 1-[4-(hydroxymethyl)cyclopent-2-enyl]-1,2,4-triazole-3-carboxamide and its derivatives.
    Nucleosides, nucleotides & nucleic acids, 2003, Volume: 22, Issue:4

    Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Nucleosides; Palladium; Ribavirin; Triazoles

2003
Synthesis of homo-N-nucleoside with 1,2,4-triazole-3-carboxamide.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; Cyanides; DNA Replication; Drug Design; Models, Chemical; Nucleic Acid Conformation; Nucleosides; Nucleotides; Ribavirin; Triazoles; Trimethylsilyl Compounds

2005
Photolabeling probes of ribavirin and EICAR.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Hepacivirus; Hepatitis C; Humans; Imidazoles; Light; Models, Chemical; Models, Molecular; Molecular Biology; Nucleosides; Photoaffinity Labels; Photolysis; Ribavirin; Ribonucleosides; Severe Acute Respiratory Syndrome; Time Factors; Triazoles

2005
Structural effects on the phosphorylation of 3-substituted 1-beta-D-ribofuranosyl-1,2,4-triazoles by human adenosine kinase.
    Bioorganic & medicinal chemistry letters, 2007, Jun-01, Volume: 17, Issue:11

    Topics: Adenosine Kinase; Antiviral Agents; Computers; Humans; Models, Molecular; Molecular Structure; Phosphorylation; Ribavirin; Stereoisomerism; Triazoles

2007
Mutagenic effect of ribavirin on hepatitis C nonstructural 5B quasispecies in vitro and during antiviral therapy.
    Gastroenterology, 2007, Volume: 132, Issue:3

    Topics: Adult; Antiviral Agents; Cell Line, Tumor; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Monosaccharides; Mutagens; Mutation; Replicon; Retrospective Studies; Ribavirin; RNA, Viral; Time Factors; Triazoles; Viral Nonstructural Proteins

2007
Hepatitis-C patients have reduced growth hormone (GH) secretion which improves during long-term therapy with pegylated interferon-alpha.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:12

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Growth Hormone; Hepatitis C, Chronic; Humans; Insulin-Like Growth Factor Binding Protein 1; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Monosaccharides; Pituitary Function Tests; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; Statistics, Nonparametric; Treatment Outcome; Triazoles

2007
Synthesis of 4-substituted-1,2,3-triazole carbanucleoside analogues of ribavirin via click chemistry.
    Organic & biomolecular chemistry, 2007, Dec-07, Volume: 5, Issue:23

    Topics: Antiviral Agents; Kinetics; Nucleosides; Ribavirin; Triazoles

2007
Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.
    Antiviral research, 2008, Volume: 79, Issue:1

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Female; Genome, Viral; Guanosine; Guanosine Triphosphate; Hemorrhagic Fever with Renal Syndrome; Humans; Mice; Mice, Inbred Strains; Mutation; Nucleosides; Orthohantavirus; Ribavirin; Triazoles; Vero Cells

2008
Huisgen cycloaddition reaction of C-alkynyl ribosides under micellar catalysis: synthesis of ribavirin analogues.
    The Journal of organic chemistry, 2009, Jun-05, Volume: 74, Issue:11

    Topics: Antiviral Agents; Catalysis; Magnetic Resonance Spectroscopy; Micelles; Molecular Structure; Ribavirin; Ribose; Triazoles

2009
Hyalohyphomycosis caused by Paecilomyces lilacinus after kidney transplantation.
    Transplantation proceedings, 2009, Volume: 41, Issue:7

    Topics: Antifungal Agents; Diabetes Mellitus; Female; Graft Rejection; Hepatitis C; Humans; Immunosuppressive Agents; Interferons; Kidney Transplantation; Middle Aged; Mycoses; Paecilomyces; Polycystic Kidney Diseases; Postoperative Complications; Pyrimidines; Renal Replacement Therapy; Ribavirin; Treatment Outcome; Triazoles; Voriconazole

2009
A novel nucleoside analog, 1-beta-d-ribofuranosyl-3-ethynyl-[1,2,4]triazole (ETAR), exhibits efficacy against a broad range of flaviviruses in vitro.
    Antiviral research, 2010, Volume: 87, Issue:1

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Flavivirus; Guanosine Triphosphate; Imidazoles; Microbial Sensitivity Tests; Nucleosides; Ribavirin; Triazoles; Vero Cells

2010
Structural modeling of the NS 3 helicase of Tick-borne encephalitis virus and their virtual screening of potent drugs using molecular docking.
    Interdisciplinary sciences, computational life sciences, 2009, Volume: 1, Issue:3

    Topics: Amino Acid Sequence; Antiviral Agents; Chemistry, Pharmaceutical; Computer Simulation; DNA Helicases; Drug Evaluation, Preclinical; Encephalitis Viruses, Tick-Borne; Genome, Viral; Molecular Conformation; Molecular Sequence Data; Monosaccharides; Ribavirin; RNA Helicases; RNA, Viral; Serine Endopeptidases; Software; Triazoles; Viral Nonstructural Proteins

2009
Cloning and characterization of purine nucleoside phosphorylase in Escherichia coli and subsequent ribavirin biosynthesis using immobilized recombinant cells.
    Enzyme and microbial technology, 2011, May-06, Volume: 48, Issue:6-7

    Topics: Agar; Biocatalysis; Cells, Immobilized; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Gels; Genes, Bacterial; Guanosine; Hydrogen-Ion Concentration; Kinetics; Purine-Nucleoside Phosphorylase; Recombinant Fusion Proteins; Ribavirin; Substrate Specificity; Temperature; Triazoles

2011
[Influence of rimantadine, ribavirine and triazavirine on influenza A virus replication in human monolayer and lymphoblastoid cell lines].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:11-12

    Topics: Antiviral Agents; Apoptosis; Azoles; Cell Culture Techniques; Cell Line; Cell Proliferation; Fibroblasts; Humans; Influenza A virus; Lymphocytes; Ribavirin; Rimantadine; Suspensions; Triazines; Triazoles; Virus Replication

2011
Antivirally active ribavirin analogues--4,5-disubstituted 1,2,3-triazole nucleosides: biological evaluation against certain respiratory viruses and computational modelling.
    Antiviral chemistry & chemotherapy, 2014, Jan-29, Volume: 23, Issue:4

    Topics: Animals; Antiviral Agents; Cell Line; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza, Human; Measles; Measles virus; Models, Molecular; Nucleosides; Orthomyxoviridae Infections; Parainfluenza Virus 3, Human; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Respirovirus Infections; Ribavirin; Triazoles

2014
Synthesis of a new series of phosphonylated 1,2,3-triazoles as acyclic analogs of ribavirin.
    Archiv der Pharmazie, 2013, Volume: 346, Issue:9

    Topics: Animals; Antiviral Agents; Cell Proliferation; Chlorocebus aethiops; DNA Viruses; HeLa Cells; Humans; Inhibitory Concentration 50; Phosphorylation; Ribavirin; RNA Viruses; Triazoles; Vero Cells

2013
[Investigation of Triazavirin antiviral activity against tick-borne encephalitis pathogen in cell culture].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2014, Volume: 59, Issue:1-2

    Topics: Animals; Antiviral Agents; Azoles; Cell Line; Encephalitis Viruses, Tick-Borne; Epithelial Cells; Kidney; Ribavirin; Swine; Triazines; Triazoles; Virus Replication

2014
[Investigation of Therapeutic Efficacy of Triazavirin Against Experimental Forest-Spring Encephalitis on Albino Mice].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2015, Volume: 60, Issue:7-8

    Topics: Animals; Antiviral Agents; Azoles; Brain; Encephalitis Viruses, Tick-Borne; Encephalitis, Tick-Borne; Mice; Ribavirin; Survival Analysis; Treatment Outcome; Triazines; Triazoles; Viral Load; Virus Replication

2015
Pyruvate dehydrogenase kinase regulates hepatitis C virus replication.
    Scientific reports, 2016, 07-29, Volume: 6

    Topics: Adult; Aged; Antiviral Agents; Azepines; Cell Line; Dichloroacetic Acid; Glucokinase; Glycolysis; Hepacivirus; Hepatocytes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interferon-alpha; Liver; Middle Aged; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Ribavirin; RNA Interference; Triazoles; Virus Replication

2016
First novel synthesis of triazole thioglycosides as ribavirin analogues.
    Nucleosides, nucleotides & nucleic acids, 2018, Feb-01, Volume: 37, Issue:2

    Topics: Molecular Structure; Ribavirin; Thioglycosides; Triazoles

2018
Chemical ribosylation of 5-substituted 1,2,4-triazole-3-carboxylates.
    Nucleosides, nucleotides & nucleic acids, 2019, Volume: 38, Issue:8

    Topics: Carboxylic Acids; Catalysis; Isomerism; Molecular Structure; Ribavirin; Structure-Activity Relationship; Triazoles

2019
Baicalein triazole prevents respiratory tract infection by RSV through suppression of oxidative damage.
    Microbial pathogenesis, 2019, Volume: 131

    Topics: Animals; Cytokines; Female; Flavanones; Interferon-beta; Interleukin-6; Interleukin-8; Lymphocytes; Mice; Mice, Inbred BALB C; Neutrophils; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pneumonia; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Respiratory Tract Infections; Ribavirin; STAT3 Transcription Factor; Triazoles; Tumor Necrosis Factor-alpha; Virus Replication

2019
5-Substituted 1,2,4-Triazole-3-Carboxylates and 5-Substituted Ribavirin Analogs Synthesis.
    Current protocols, 2021, Volume: 1, Issue:11

    Topics: Carboxylic Acids; Nucleosides; Ribavirin; Triazoles

2021
Synthesis of ribavirin 1,2,3- and 1,2,4-triazolyl analogs with changes at the amide and cytotoxicity in breast cancer cell lines.
    Nucleosides, nucleotides & nucleic acids, 2023, Volume: 42, Issue:1

    Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Female; Humans; MCF-7 Cells; Ribavirin; Structure-Activity Relationship; Triazoles

2023