Compounds > triazoles
Page last updated: 2024-08-24

triazoles and plx4032

triazoles has been researched along with plx4032 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Baer, C; Breyssens, H; Brown, NR; Caballero, OL; Cebon, J; Endicott, J; Goding, CR; Hu, Y; John, T; Jones, EY; Kessler, BM; Knapp, S; Lu, M; Lu, X; Middleton, MR; Ratnayaka, I; Salter, V; Siebold, C; Sullivan, A; Sviderskaya, EV; Zhong, S1
Acquaviva, J; Bates, RC; He, S; Jimenez, JP; Proia, DA; Sang, J; Sequeira, M; Smith, DL; Zhang, C1
Buijsman, RC; de Man, J; de Roos, JA; de Vetter, JR; Prinsen, MB; Spijkers-Hagelstein, JA; Uitdehaag, JC; van Doornmalen, AM; Zaman, GJ1
Bradner, JE; Darvishian, F; Hanniford, D; Hernando, E; Osman, I; Paoluzzi, L; Sokolova, E; Wang, J1
Beltran, P; Caenepeel, S; Cajulis, E; Cooke, K; Coxon, A; Huang, G; Hughes, PE; Kendall, R; Moreno, BH; Parisi, G; Ribas, A; Robert, L; Wadsworth, S1
Hattori, N; Iida, N; Kimura, K; Mori, A; Nakamura, Y; Ushijima, T; Yamashita, S; Yoshino, T1
Cheng, X; Zhao, B; Zhou, X1
Bantscheff, M; Becher, I; Bergamini, G; Childs, DD; Eberl, HC; Faelth-Savitski, M; Franken, H; Heller, B; Huber, W; Kalxdorf, M; Krause, J; Kurzawa, N; Perrin, J; Poeckel, D; Rau, CE; Rutkowska, A; Savitski, MM; Sevin, DC; Stonehouse, E; Strohmer, K; Thomson, DW; Vappiani, J; Werner, T1
Adderley, T; Christopher, G; Irwin, MS; Kano, Y; Kee, L; Ladumor, Y; Ohh, M; Robinson, CM; Valencia-Sama, I1

Other Studies

9 other study(ies) available for triazoles and plx4032

ArticleYear
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
    Cancer cell, 2013, May-13, Volume: 23, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin B1; Dimerization; Humans; Imidazoles; Indoles; Intracellular Signaling Peptides and Proteins; M Phase Cell Cycle Checkpoints; Melanoma; Mice; Neoplasm Metastasis; Nocodazole; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-mdm2; Repressor Proteins; Sulfonamides; Triazoles; Tumor Suppressor Protein p53; Vemurafenib; Xenograft Model Antitumor Assays

2013
Overcoming acquired BRAF inhibitor resistance in melanoma via targeted inhibition of Hsp90 with ganetespib.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Blotting, Western; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; HSP90 Heat-Shock Proteins; Humans; Indoles; Melanoma; Mice, Nude; Mice, SCID; Mitogen-Activated Protein Kinase Kinases; Mutation; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Sulfonamides; Triazoles; Vemurafenib; Xenograft Model Antitumor Assays

2014
Selective Targeting of CTNBB1-, KRAS- or MYC-Driven Cell Growth by Combinations of Existing Drugs.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aza Compounds; Benzimidazoles; beta Catenin; Cell Line, Tumor; Cell Proliferation; Humans; Imidazoles; Indazoles; Indoles; Melanoma; Molecular Targeted Therapy; Mutation; Oxazoles; Oximes; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); Pyridones; Pyrimidinones; Quinolines; Sulfonamides; Triazoles; Vemurafenib

2015
BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.
    Cancer medicine, 2016, Volume: 5, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Melanoma; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Sulfonamides; Transcription, Genetic; Triazoles; Vemurafenib; Xenograft Model Antitumor Assays

2016
MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor.
    Oncotarget, 2017, Mar-14, Volume: 8, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Dipeptides; Diphenylamine; Drug Resistance, Neoplasm; Female; Hepatocyte Growth Factor; Humans; Indoles; MAP Kinase Signaling System; Melanoma; Mice; Mice, Nude; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-met; Pyridones; Sulfonamides; Triazoles; Vemurafenib; Xenograft Model Antitumor Assays

2017
Targeting of super-enhancers and mutant BRAF can suppress growth of BRAF-mutant colon cancer cells via repression of MAPK signaling pathway.
    Cancer letters, 2017, 08-28, Volume: 402

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Caco-2 Cells; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HCT116 Cells; HT29 Cells; Humans; Indoles; Inhibitory Concentration 50; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Mutation; Phenotype; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Signal Transduction; Sulfonamides; Time Factors; Triazoles; Tumor Burden; Vemurafenib; Xenograft Model Antitumor Assays

2017
The BET-bromodomain inhibitor JQ1 mitigates vemurafenib drug resistance in melanoma.
    Melanoma research, 2018, Volume: 28, Issue:6

    Topics: Animals; Antineoplastic Agents; Azepines; Drug Resistance, Neoplasm; Humans; Melanoma; Mice; Proto-Oncogene Proteins B-raf; Triazoles; Vemurafenib

2018
Identifying drug targets in tissues and whole blood with thermal-shift profiling.
    Nature biotechnology, 2020, Volume: 38, Issue:3

    Topics: Animals; Azepines; Blood; Hep G2 Cells; Humans; Kidney; Liver; Lung; Male; Mass Spectrometry; Mice; Organ Specificity; Panobinostat; Protein Stability; Proteome; Rats; Small Molecule Libraries; Spleen; Testis; Thermodynamics; Triazoles; Vemurafenib

2020
    Cancer research, 2020, 08-15, Volume: 80, Issue:16

    Topics: Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Genes, ras; Heterografts; Humans; Indoles; Male; MAP Kinase Signaling System; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase Kinases; Mutation; Neoplasm Recurrence, Local; Neuroblastoma; Piperidines; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pyridones; Pyrimidines; Pyrimidinones; Pyrroles; Triazoles; Vemurafenib

2020