Page last updated: 2024-08-24

triazoles and phenylalanine

triazoles has been researched along with phenylalanine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's4 (14.29)18.2507
2000's5 (17.86)29.6817
2010's12 (42.86)24.3611
2020's5 (17.86)2.80

Authors

AuthorsStudies
Göttinger, E1
Gueguen, P; Hervé, G; Padron, M; Perbal, B1
Escher, E; Gouill, CL; Parent, JL; Rola-Pleszczynski, M; Staková, J1
Kuwano, M; Ono, M1
Corio-Costet, MF; Délye, C; Laigret, F1
Bu, W; Li, XM; Qin, LX; Tang, ZY; Xia, JL1
Bentin, T; Hamzavi, R; Ibba, M; Nielsen, PE; Roy, H; Salomonsson, J1
Beconi, M; Di Salvo, J; Edmondson, SD; Eiermann, GJ; Harper, B; He, H; He, J; Leiting, B; Leone, JF; Levorse, DA; Lyons, K; Mastracchio, A; Mathvink, RJ; Park, YJ; Patel, RA; Patel, SB; Petrov, A; Roy, RS; Scapin, G; Shang, J; Smith, A; Thornberry, NA; Weber, AE; Wu, JK; Xu, S; Zhu, B1
Baillie, TA; Bleasby, K; Chen, Q; Colletti, A; Dean, DC; Evers, R; Hafey, M; Hagmann, WK; Lanza, TJ; Lin, LS; Magriotis, PA; Stearns, RA; Tang, W; Teffera, Y1
Desbrieres, J; Moise, M; Peptu, C; Popa, M; Profire, L; Sunel, V1
Busscher, HJ; Lageveen, LT; Llamas-Saiz, AL; Mars-Groenendijk, R; Noort, D; Otero, JM; Overhand, M; Overkleeft, HS; van der Knaap, M; van der Marel, GA; van Raaij, MJ1
Fang, Q; Feng, C; Gu, G; Hou, J; Li, Z; Liu, P; Shen, J; Shi, Y; Wang, H; Wang, P; Xu, F; Yin, Z1
Chang, YC; Dolan, MA; Garraffo, HM; Ghannoum, MA; Kwon-Chung, KJ; Sionov, E1
Allister, EM; Bhattacharjee, A; Wheeler, MB1
Chen, M; Guo, Z; Hao, J; Houze, J; Lin, DC; Lopez, E; Luo, J; Ma, Z; Nguyen, K; Rulifson, IC; Tian, B; Tian, L; Tran, T; Wang, Y; Zhang, Y1
Hu, Y; Li, J; Liu, T; Liu, Y; Ma, X; Shangguan, S; Si, M; Tang, L; Wu, H; Wu, P1
Dong, CJ; Li, L; Liu, XY; Shang, QM; Zhang, ZG1
Coderch, C; de Pascual-Teresa, B; Filipiak, K; Puckowska, A; Ramos, A; Zapico, JM1
Huber, T; Naganathan, S; Park, M; Ray-Saha, S; Sakmar, TP; Tian, H1
Başaran, E; Karaküçük-Iyidoğan, A; Oruç-Emre, EE; Schols, D1
Finn, LA; Hussar, DA1
Hussar, DA1
Chen, CH; Cocklin, S; Dick, A; Ding, X; Gao, P; Huang, T; Lee, KH; Liu, X; Meuser, ME; Sun, L; Zalloum, WA; Zhan, P1
Earl, DC; Van Tyle, KM1
Alonso-Del-Real, J; Briz-Cid, N; Querol, A; Rial-Otero, R; Sieiro-Sampedro, T; Simal-Gandara, J1
Arjunan, P; Manturthi, S; Marepally, S; Patri, SV; Rapaka, H; Thangavel, S; Venkatesan, V1
Fan, J; Guo, D; He, R; Ji, C; Zhao, M1

Reviews

4 review(s) available for triazoles and phenylalanine

ArticleYear
[Development of anti tumor agents targeting angiogenesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclohexanes; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Interferon-alpha; Interleukin-12; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Platelet Factor 4; Polysaccharides, Bacterial; Sesquiterpenes; Thalidomide; Thiophenes; Triazines; Triazoles; Tumor Cells, Cultured

1997
Drugs for type 2 diabetes.
    Treatment guidelines from the Medical Letter, 2008, Volume: 6, Issue:71

    Topics: alpha-Galactosidase; Biguanides; Carbamates; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Combinations; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin; Nateglinide; Phenylalanine; Piperidines; Pyrazines; Sitagliptin Phosphate; Sulfonylurea Compounds; Thiazolidinediones; Triazoles

2008
NewDrugs 2017, part 2.
    Nursing, 2017, Volume: 47, Issue:7

    Topics: Amides; Antibodies, Monoclonal, Humanized; Benzofurans; Carbamates; Cyclopropanes; Drug Approval; Drug Therapy; gamma-Cyclodextrins; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Peptides; Phenylalanine; Quinoxalines; Sofosbuvir; Sugammadex; Sulfonamides; Sulfones; Thioglycolates; Triazoles; United States; United States Food and Drug Administration

2017
New pharmacologic agents for insomnia and hypersomnia.
    Current opinion in pulmonary medicine, 2020, Volume: 26, Issue:6

    Topics: Azepines; Carbamates; Dementia; Disorders of Excessive Somnolence; GABA-A Receptor Agonists; Humans; Orexin Receptor Antagonists; Phenylalanine; Piperidines; Pyridines; Pyrimidines; Sleep Aids, Pharmaceutical; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Trazodone; Triazoles; Zolpidem

2020

Other Studies

24 other study(ies) available for triazoles and phenylalanine

ArticleYear
[Toxicology of chemical sweetening agents].
    Wiener medizinische Wochenschrift (1946), 1971, Jun-19, Volume: 121, Issue:25

    Topics: Abnormalities, Drug-Induced; Animals; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Cyclamates; Cyclohexylamines; Depression, Chemical; Esters; Guinea Pigs; Humans; Kidney Diseases; Mice; Pancreatic Diseases; Peptides; Phenylalanine; Photosensitivity Disorders; Rats; Saccharin; Sweetening Agents; Tolbutamide; Triazoles; Urinary Bladder Neoplasms

1971
Incorporation of amino acid analogs during the biosynthesis of Escherichia coli aspartate transcarbamylase.
    Biochimica et biophysica acta, 1980, Sep-09, Volume: 615, Issue:1

    Topics: Alanine; Amino Acids; Aspartate Carbamoyltransferase; Escherichia coli; Ethionine; Macromolecular Substances; Methylhistidines; p-Fluorophenylalanine; Phenylalanine; Triazoles; Tryptophan

1980
Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis.
    The Journal of biological chemistry, 1996, Sep-20, Volume: 271, Issue:38

    Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Azepines; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Conformation; Proto-Oncogene Proteins c-myc; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Transfection; Triazoles

1996
A mutation in the 14 alpha-demethylase gene of Uncinula necator that correlates with resistance to a sterol biosynthesis inhibitor.
    Applied and environmental microbiology, 1997, Volume: 63, Issue:8

    Topics: Alleles; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Fungi; Fungicides, Industrial; Molecular Sequence Data; Oxidoreductases; Phenylalanine; Point Mutation; Polymerase Chain Reaction; Sterol 14-Demethylase; Sterols; Triazoles; Tyrosine

1997
Effect of antiangiogenic agents on experimental animal models of hepatocellular carcinoma.
    Annals of the Academy of Medicine, Singapore, 1999, Volume: 28, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Cyclohexanes; Liver Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Sesquiterpenes; Suramin; Thiophenes; Triazoles

1999
Photoreactive bicyclic amino acids as substrates for mutant Escherichia coli phenylalanyl-tRNA synthetases.
    The Journal of biological chemistry, 2004, May-07, Volume: 279, Issue:19

    Topics: Alanine; Amino Acids; Benzofurans; Escherichia coli; Kinetics; Mass Spectrometry; Models, Chemical; Mutagenesis; Phenylalanine; Phenylalanine-tRNA Ligase; Protein Binding; Protein Engineering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Time Factors; Triazoles; Ultraviolet Rays

2004
(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
    Journal of medicinal chemistry, 2006, Jun-15, Volume: 49, Issue:12

    Topics: Administration, Oral; Animals; Biological Availability; Calcium Channels, L-Type; Cell Line; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Glucose Tolerance Test; Humans; Hypoglycemic Agents; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Microsomes, Liver; Models, Molecular; Muscle Proteins; Muscle, Skeletal; NAV1.5 Voltage-Gated Sodium Channel; Phenylalanine; Protease Inhibitors; Rabbits; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Triazoles

2006
Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:2

    Topics: Animals; Cells, Cultured; Cyclosporine; Dogs; Inactivation, Metabolic; Integrin alpha4beta1; Microsomes, Liver; Organic Anion Transporters, Sodium-Independent; Phenylalanine; Rats; Rats, Sprague-Dawley; Solute Carrier Organic Anion Transporter Family Member 1B3; Time Factors; Triazoles

2008
Synthesis and biological activity of some new 1,3,4-thiadiazole and 1,2,4-triazole compounds containing a phenylalanine moiety.
    Molecules (Basel, Switzerland), 2009, Jul-16, Volume: 14, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Male; Mice; Phenylalanine; Rats; Thiadiazoles; Triazoles

2009
Evaluation of readily accessible azoles as mimics of the aromatic ring of D-phenylalanine in the turn region of gramicidin S.
    ChemMedChem, 2011, May-02, Volume: 6, Issue:5

    Topics: Anti-Bacterial Agents; Crystallography, X-Ray; Erythrocytes; Gram-Negative Bacteria; Gram-Positive Bacteria; Gramicidin; Humans; Microbial Sensitivity Tests; Molecular Conformation; Phenylalanine; Triazoles

2011
Structure-based optimization of click-based histone deacetylase inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxamic Acids; Models, Molecular; Neoplasms; Phenylalanine; Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Triazoles; Vorinostat

2011
Identification of a Cryptococcus neoformans cytochrome P450 lanosterol 14α-demethylase (Erg11) residue critical for differential susceptibility between fluconazole/voriconazole and itraconazole/posaconazole.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3

    Topics: 14-alpha Demethylase Inhibitors; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Fungal; Female; Fluconazole; Fungal Proteins; Genotype; Humans; Itraconazole; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mutation, Missense; Phenylalanine; Pyrimidines; Sterol 14-Demethylase; Survival Rate; Triazoles; Tyrosine; Voriconazole

2012
MK-626, a dipeptidyl peptidase-4 inhibitor, does not improve the hyperglycemia or hyperinsulinemia of nonobese diabetic MKR mice.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Glucagon; Glucose; Glucose Intolerance; Homeostasis; Hyperglycemia; Hyperinsulinism; Incretins; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Obese; Phenylalanine; Triazoles

2012
Evaluating insulin secretagogues in a humanized mouse model with functional human islets.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:1

    Topics: Animals; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Exenatide; Glucagon-Like Peptide 1; Glucose Tolerance Test; Glyburide; Humans; Incretins; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Nude; Nateglinide; Peptides; Phenylalanine; Pyrazines; Sitagliptin Phosphate; Specific Pathogen-Free Organisms; Triazoles; Venoms

2013
Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors.
    Bioorganic & medicinal chemistry, 2013, Sep-15, Volume: 21, Issue:18

    Topics: Animals; Binding Sites; Blood Glucose; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Glucose Tolerance Test; Molecular Docking Simulation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Pyrazines; Rats; Rats, Sprague-Dawley; Sitagliptin Phosphate; Structure-Activity Relationship; Triazoles

2013
Endogenous salicylic acid accumulation is required for chilling tolerance in cucumber (Cucumis sativus L.) seedlings.
    Planta, 2014, Volume: 240, Issue:4

    Topics: Antioxidants; Chlorophyll; Cold Temperature; Cucumis sativus; Hydrogen Peroxide; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Growth Regulators; Plant Proteins; Salicylic Acid; Seedlings; Stress, Physiological; Triazoles

2014
Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family.
    Organic & biomolecular chemistry, 2015, Jan-07, Volume: 13, Issue:1

    Topics: Chemistry Techniques, Synthetic; Drug Design; Gelatinases; Hydroxamic Acids; Matrix Metalloproteinase Inhibitors; Molecular Docking Simulation; Molecular Dynamics Simulation; Phenylalanine; Substrate Specificity; Triazoles

2015
Multiplex detection of functional G protein-coupled receptors harboring site-specifically modified unnatural amino acids.
    Biochemistry, 2015, Jan-27, Volume: 54, Issue:3

    Topics: Amino Acids; Azides; Cyclohexanes; Epitopes; Fluorescent Dyes; HEK293 Cells; Humans; Immunoassay; Maraviroc; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Receptors, CCR5; Triazoles

2015
Synthesis of Novel Chiral Sulfonamide-Bearing 1,2,4-Triazole-3-thione Analogs Derived from D- and L-Phenylalanine Esters as Potential Anti-Influenza Agents.
    Chirality, 2016, Volume: 28, Issue:6

    Topics: Animals; Antiviral Agents; Chemistry Techniques, Synthetic; Dogs; Drug Evaluation, Preclinical; HeLa Cells; Humans; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Triazoles

2016
2017 New Drug Update.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2017, May-01, Volume: 32, Issue:5

    Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Drugs, Investigational; Dry Eye Syndromes; Gout Suppressants; Humans; Hypoglycemic Agents; Insulin, Long-Acting; Peptides; Phenylalanine; Piperidines; Sulfones; Thioglycolates; Triazoles; Urea

2017
Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities.
    European journal of medicinal chemistry, 2020, Mar-15, Volume: 190

    Topics: Anti-HIV Agents; Capsid Proteins; Cell Line, Tumor; Drug Design; HIV-1; Humans; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Dynamics Simulation; Molecular Structure; Phenylalanine; Protein Binding; Structure-Activity Relationship; Triazoles; Virus Replication

2020
The effect of two antifungal commercial formulations on the metabolism of a commercial Saccharomyces cerevisiae strain and their repercussion on fermentation evolution and phenylalanine catabolism.
    Food microbiology, 2020, Volume: 92

    Topics: Antifungal Agents; Biomass; Chlorobenzenes; Ethanol; Fermentation; Metabolic Networks and Pathways; Phenylalanine; Pyrimidines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triazoles

2020
Influence of Hydrophobicity in the Hydrophilic Region of Cationic Lipids on Enhancing Nucleic Acid Delivery and Gene Editing.
    ACS applied bio materials, 2022, 04-18, Volume: 5, Issue:4

    Topics: alpha-Tocopherol; Amino Acids; Cations; Gene Editing; Gene Transfer Techniques; Hydrophobic and Hydrophilic Interactions; Lipids; Nucleic Acids; Phenylalanine; Triazoles; Tryptophan

2022
Triticonazole enantiomers induced enantioselective metabolic phenotypes in Fusarium graminearum and HepG2 cells.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:50

    Topics: Alanine; Aspartic Acid; Cyclopentanes; Fungicides, Industrial; Fusarium; Glutamates; Hep G2 Cells; Humans; Phenotype; Phenylalanine; Plant Diseases; Pyruvates; Stereoisomerism; Taurine; Triazoles

2022