Page last updated: 2024-08-24

triazoles and panobinostat

triazoles has been researched along with panobinostat in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Chen, S; Evans, D; Kijima, I; Ye, J1
Chen, S; Chu, P; Kanaya, N; Kubo, M; Liu, Z; Nishimura, R; Okido, M; Osako, T; Petrossian, K; Shimada, K; Takahashi, M; Warden, C; Ye, J; Yuan, YC1
Bullen, CK; Durand, CM; Laird, GM; Siliciano, JD; Siliciano, RF1
Cheng, WJ; Churchill, MJ; Ellett, AM; Gorry, PR; Gray, LR; Jacobson, JC; Lewin, SR; Lu, HK; Moso, MA; On, H; Papaioannou, C; Purcell, DF; Raison, JA; Roberts, E; Wesselingh, SL1
Atmadibrata, B; Bradner, JE; Liu, PY; Liu, T; Lock, RB; Marshall, GM; Shahbazi, J1
Allred, JB; Goetz, MP; Ingle, JN; Moreno-Aspitia, A; Northfelt, DW; Perez, EA; Tan, WW1
Hulleman, E; Li, M; Liu, F; Ma, J; Meng, W; Monje, M; Nagaraja, S; Ponnuswami, A; Sun, W; Swigut, T; Tang, Y; Taylor, KR; Vitanza, NA; Woo, PJ; Wysocka, J; Zhang, L1
Boeva, V; De Preter, K; De Vloed, F; De Wyn, J; Decaesteker, B; Deforce, D; Denecker, G; Depuydt, P; Dolman, EM; Dreidax, D; Durinck, K; Essing, AHW; Gartlgruber, M; Henssen, A; Herrmann, C; Kholosy, WM; Koopmans, B; Loontiens, S; Mestdagh, P; Molenaar, JJ; Nunes, C; Rombaut, D; Schleiermacher, G; Schulte, JH; Speleman, F; Van Loocke, W; van Nes, J; Van Neste, C; Van Nieuwerburgh, F; Vanhauwaert, S; Verboom, K; Versteeg, R; Westermann, F1
Bantscheff, M; Becher, I; Bergamini, G; Childs, DD; Eberl, HC; Faelth-Savitski, M; Franken, H; Heller, B; Huber, W; Kalxdorf, M; Krause, J; Kurzawa, N; Perrin, J; Poeckel, D; Rau, CE; Rutkowska, A; Savitski, MM; Sevin, DC; Stonehouse, E; Strohmer, K; Thomson, DW; Vappiani, J; Werner, T1
Alexander, G; Challagundla, KB; Chaturvedi, NK; Coulter, DW; Joshi, SS; Kesherwani, V; Kling, MJ; McIntyre, EM; Mishra, NK; Ray, S1

Trials

1 trial(s) available for triazoles and panobinostat

ArticleYear
Phase I Study of Panobinostat (LBH589) and Letrozole in Postmenopausal Metastatic Breast Cancer Patients.
    Clinical breast cancer, 2016, Volume: 16, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Indoles; Letrozole; Lymphatic Metastasis; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Panobinostat; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Triazoles

2016

Other Studies

9 other study(ies) available for triazoles and panobinostat

ArticleYear
The HDAC inhibitor LBH589 (panobinostat) is an inhibitory modulator of aromatase gene expression.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jun-15, Volume: 107, Issue:24

    Topics: Aromatase; Aromatase Inhibitors; Base Sequence; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-delta; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; DNA Primers; Down-Regulation; Drug Synergism; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Panobinostat; Promoter Regions, Genetic; Triazoles

2010
Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat).
    Breast cancer research and treatment, 2013, Volume: 137, Issue:1

    Topics: Aged; Androstadienes; Animals; Antineoplastic Agents; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Letrozole; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; NF-kappa B p50 Subunit; Nitriles; Panobinostat; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays

2013
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.
    Nature medicine, 2014, Volume: 20, Issue:4

    Topics: Anti-HIV Agents; Azepines; Bryostatins; CD4-Positive T-Lymphocytes; Cell Cycle Proteins; Depsipeptides; Disulfiram; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Hydroxamic Acids; Indoles; Ionomycin; Lymphocyte Activation; Nuclear Proteins; Panobinostat; Tetradecanoylphorbol Acetate; Transcription Factors; Triazoles; Virus Latency; Vorinostat

2014
Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells.
    Journal of neurovirology, 2016, Volume: 22, Issue:4

    Topics: Acetamides; Astrocytes; Azepines; Cell Line; Cell Survival; Depsipeptides; Disulfiram; Fetus; Histone Deacetylase Inhibitors; HIV-1; Humans; Hydroxamic Acids; Indoles; Macrophages; Neurons; Panobinostat; Piperazines; Primary Cell Culture; Transcription, Genetic; Triazoles; Virus Activation; Virus Latency; Virus Replication; Vorinostat

2016
The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, 05-15, Volume: 22, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Line, Tumor; Cell Proliferation; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Mice; Mice, Inbred BALB C; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Panobinostat; Promoter Regions, Genetic; Proteins; Proto-Oncogene Proteins c-myc; Transcription, Genetic; Triazoles; Xenograft Model Antitumor Assays

2016
Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.
    Cancer cell, 2017, 05-08, Volume: 31, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Brain Stem Neoplasms; Cell Cycle Proteins; Cell Proliferation; Chromatin Assembly and Disassembly; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glioma; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Indoles; Male; Mice, Inbred NOD; Mice, SCID; Mutation; Nuclear Proteins; Panobinostat; Phenylenediamines; Primary Cell Culture; Protein Kinase Inhibitors; Pyrimidines; Receptors, Eph Family; RNA Interference; Signal Transduction; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2017
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
    Nature communications, 2018, 11-19, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Azepines; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; DNA Copy Number Variations; Epigenesis, Genetic; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Kv Channel-Interacting Proteins; N-Myc Proto-Oncogene Protein; Neuroblastoma; Organoids; Panobinostat; Phenylenediamines; Pyrimidines; Repressor Proteins; Signal Transduction; T-Box Domain Proteins; Triazoles; Tumor Suppressor Protein p53

2018
Identifying drug targets in tissues and whole blood with thermal-shift profiling.
    Nature biotechnology, 2020, Volume: 38, Issue:3

    Topics: Animals; Azepines; Blood; Hep G2 Cells; Humans; Kidney; Liver; Lung; Male; Mass Spectrometry; Mice; Organ Specificity; Panobinostat; Protein Stability; Proteome; Rats; Small Molecule Libraries; Spleen; Testis; Thermodynamics; Triazoles; Vemurafenib

2020
A novel dual epigenetic approach targeting BET proteins and HDACs in Group 3 (MYC-driven) Medulloblastoma.
    Journal of experimental & clinical cancer research : CR, 2022, Nov-11, Volume: 41, Issue:1

    Topics: Animals; Apoptosis; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Epigenesis, Genetic; Histone Deacetylases; Humans; Medulloblastoma; Mice; Nuclear Proteins; Panobinostat; Proto-Oncogene Proteins c-myc; Transcription Factors; Triazoles

2022