triazoles has been researched along with ovalbumin in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (9.62) | 18.7374 |
| 1990's | 33 (63.46) | 18.2507 |
| 2000's | 6 (11.54) | 29.6817 |
| 2010's | 6 (11.54) | 24.3611 |
| 2020's | 2 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, JN | 1 |
| Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB | 1 |
| Fisher, RA; Hines, KL | 1 |
| Iwahisa, Y; Okamoto, H; Terasawa, M | 1 |
| Bozza, PT; COrdeiro, RS; Faria Neto, HC; Martins, MA; Pasquale, CP; Silva, PM | 1 |
| Aibara, S; Fujiwara, H; Iwamoto, T; Matsumoto, H; Miwa, T; Mori, M; Moroi, R; Nakayama, K; Tsukada, W; Yokohama, S | 1 |
| Lewis, SA; Raeburn, D; Underwood, SL | 1 |
| Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB | 1 |
| Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M | 1 |
| Harada, K; Katayama, K; Katayama, S; Muramoto, K; Sakuma, Y; Tsunoda, H | 1 |
| Herbert, JM; Lespy, L; Maffrand, JP | 1 |
| Heuer, HO | 2 |
| Braquet, P; Friedrich, G; Giessler, J; Hirschelmann, R; Madi, S | 1 |
| Arima, M; Makino, S; Sagara, H; Terashi, Y; Yukawa, T | 1 |
| Egan, RW; Fernandez, X; Gulbenkian, AR; Kreutner, W; Kung, T; Minnicozzi, M; Watnick, AS | 1 |
| Pretolani, M; Randon, J; Vargaftig, BB | 1 |
| Conklyn, M; Showell, HJ; Watson, JW | 1 |
| Cappelletti, S; Chersi, A; Chillemi, F; Francescato, P | 1 |
| Desquand, S; Dumarey, C; Lefort, J; Vargaftig, BB | 1 |
| Casals-Stenzel, J; Heuer, H | 1 |
| Aursudkij, B; Barnes, PJ; Chung, KF; Dent, G; Evans, TW; Rogers, DF | 1 |
| Casals-Stenzel, J | 1 |
| Davies, GE; Evans, DP | 1 |
| Brown, R; Coutts, S; Dally-Meade, V; Huang, F; Jariwala, N; Khandwala, A; Loev, B; Musser, J; Van Inwegen, R; Weinryb, I | 1 |
| Choi, IH; Ha, TY; Lee, DG; Lee, HK; Lee, JH; Park, JS; Park, YM | 1 |
| Hakusui, H; Murayama, N; Nakaoka, M; Nomura, H | 1 |
| Asakura, K; Narita, S | 1 |
| Dahlén, SE; Jonsson, EW | 1 |
| Bozza, PT; Castro Faria Neto, HC; Cordeiro, RS; e Silva, PM; Lima, MC; Martins, MA; Vargaftig, BB | 1 |
| Boichot, E; Braquet, P; Lagente, V; Mencia-Huerta, JM | 1 |
| Amorim, CZ; Cordeiro, RS; Vargaftig, BB | 1 |
| Heuer, HO; Jennewein, HM; Urich, K; Wenz, B | 1 |
| Iwahisa, Y; Kagoshima, M; Kawakami, Y; Matsuura, M; Terasawa, M; Tomomatsu, N; Yamaguchi, S | 1 |
| Fuchigami, J; Hata, H; Ikegami, K; Kohjimoto, Y; Tanaka, K; Tasaka, K; Uchida, S | 1 |
| Makino, H; Ohta, Y; Sohda, T; Yamane, M | 1 |
| Ibbotson, G; Kubes, P; Scott, RB; Withers, GD | 1 |
| Boichot, E; Braquet, P; Carre, C; Guinot, P; Lagente, V; Mencia-Huerta, JM | 1 |
| Komatsu, H; Tomomatsu, N; Yamaguchi, S | 1 |
| Broadley, KJ; Spruntulis, LM | 1 |
| Ellis, KM; Fozard, JR; Mazzoni, L; Tigani, B; Villela Dantas, MF | 1 |
| Assreuy, AM; Feitosa, RF; Lima, AA; Melcíades, GB; Ribeiro, RA; Rocha, MF | 1 |
| Chi, EY; Henderson, WR; Kahn, M; Nguyen, C; Teo, JL | 1 |
| Imoto, K; Kato, M; Miyaji, S; Miyake, H; Nakamura, M; Oda, T | 1 |
| Nader, MA | 1 |
| El-Agamy, DS; El-Awady, MS; Nader, MA; Shalaby, AA | 1 |
| Bhunia, D; Bonam, SR; Halmuthur, MS; Pallavi, PM; Reddy, SA; Verma, Y | 1 |
| Bizzarro, B; Jancar, S; Koga, MM; Rios, FJ; Sá-Nunes, A | 1 |
| Hu, GZ; Hu, QH; Li, QG; Liu, ZQ; Wang, J; Wu, G; Zhu, XH | 1 |
| Akhtar, W; Akhter, M; Alam, MM; Anwer, T; Bakht, A; Khan, MF; Rizvi, MA; Shaquiquzzaman, M; Verma, G | 1 |
| Funakoshi, Y; Hongu, T; Ishitsuka, A; Kanaho, Y; Kawaguchi, A; Kuroki, T; Lee, S; Lin, YH; Nagata, K; Shibuya, A | 1 |
| Bušljeta, M; Car, Ž; Ivanković, S; Mihelec, D; Paurević, M; Petrović Peroković, V; Ribić, R; Stojković, R | 1 |
1 trial(s) available for triazoles and ovalbumin
| Article | Year |
|---|---|
Radioimmunoassay for DS-4574, an antiallergic agent: development, evaluation, and application to human plasma samples.
Topics: Adult; Animals; Antibody Specificity; Cross Reactions; Haptens; Humans; Leukotriene Antagonists; Magnetic Resonance Spectroscopy; Male; Ovalbumin; Pyrimidines; Quality Control; Rabbits; Radioimmunoassay; Triazoles | 1994 |
51 other study(ies) available for triazoles and ovalbumin
| Article | Year |
|---|---|
[Interference of platelet-activating factor antagonist, BN50739 with the releasing of inflammatory mediators from anaphylactic lung of guinea pig].
Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Female; Guinea Pigs; Histamine; Lung; Male; Ovalbumin; Platelet Activating Factor; Prostaglandins F; SRS-A; Thromboxane B2; Triazoles | 1992 |
Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats.
Topics: Anaphylaxis; Animals; Azepines; Dihydropyridines; Dose-Response Relationship, Drug; Hematocrit; Histamine H1 Antagonists; Leukocyte Count; Male; Meclizine; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Terfenadine; Triazoles | 1992 |
Regulation of hepatic glycogenolysis and vasoconstriction during antigen-induced anaphylaxis.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Eicosanoids; Epitopes; Female; Glycogen; Liver; Nitric Oxide; Ovalbumin; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles; Vasoconstriction | 1992 |
Suppression of the Arthus reaction by Y-24180, a potent and specific antagonist of platelet-activating factor.
Topics: Animals; Arthus Reaction; Azepines; Capillary Permeability; Disease Models, Animal; Female; Guinea Pigs; Male; Molecular Structure; Ovalbumin; Pancreatitis; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Skin; Skin Diseases; Triazoles | 1992 |
Homologous tachyphylaxis to bradykinin and its interference with allergic pleurisy in actively sensitized rats.
Topics: Amino Acid Sequence; Animals; Azepines; Bradykinin; Diterpenes; Dose-Response Relationship, Drug; Edema; Female; Fibrinolytic Agents; Ginkgolides; Lactones; Leukocyte Count; Male; Molecular Sequence Data; Ovalbumin; Plant Extracts; Pleurisy; Rats; Rats, Wistar; Tachyphylaxis; Triazoles | 1992 |
Synthesis and antiallergy activity of [1,3,4]thiadiazolo[3,2-a]-1,2,3-triazolo[4,5-d]pyrimidin-9(3H)-one derivatives. II. 6-Alkyl- and 6-cycloalkylalkyl derivatives.
Topics: Animals; Female; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Lung; Muscle Contraction; Ovalbumin; Passive Cutaneous Anaphylaxis; Pyrimidines; Rats; Rats, Sprague-Dawley; SRS-A; Thiadiazoles; Triazoles; X-Ray Diffraction | 1992 |
RP 59227, a novel PAF receptor antagonist: effects in guinea pig models of airway hyperreactivity.
Topics: Animals; Antigens; Azepines; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Pyridines; Thiazoles; Triazoles | 1992 |
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Azepines; Cimetidine; Dexamethasone; Edema; Male; Meclizine; Methysergide; Mice; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Triazoles | 1991 |
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Male; Myocardial Contraction; Ovalbumin; Platelet Activating Factor; Pyrilamine; Triazoles | 1990 |
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; Triazoles | 1991 |
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles | 1991 |
Effect of the hetrazepinoic platelet-activating factor antagonist Bepafant (WEB 2170) in models of active and passive anaphylaxis in mice and guinea pigs.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Lung; Male; Mice; Mice, Inbred Strains; Ovalbumin; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Propranolol; Pyrilamine; Respiration; Triazoles | 1991 |
Inhibition of active anaphylaxis in mice and guinea pigs by the new hetrazepinoic PAF antagonist bepafant (WEB 2170).
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Bronchoconstriction; Guinea Pigs; Immunization; Male; Mice; Ovalbumin; Platelet Activating Factor; Propranolol; Pulmonary Ventilation; Pyrilamine; Triazoles | 1991 |
Allergen-induced bronchospasm in passively sensitized guinea pigs: influence of new substances in comparison to reference compounds.
Topics: Acrylates; Allergens; Animals; Azepines; Benzoates; Bronchial Spasm; Disease Models, Animal; Guinea Pigs; Immunization, Passive; Male; Ovalbumin; Phospholipases A; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles | 1991 |
[Involvement of platelet activating factor (PAF) in ovalbumin antigen-induced late asthmatic response and increase of airway hyperresponsiveness in a guinea pig experimental model of asthma].
Topics: Airway Resistance; Animals; Asthma; Azepines; Disease Models, Animal; Guinea Pigs; Hypersensitivity, Delayed; Male; Ovalbumin; Platelet Activating Factor; Triazoles | 1991 |
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Histamine; Immunization; Indomethacin; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Naphthyridines; Ovalbumin; Platelet Activating Factor; Pyrazoles; Thromboxanes; Triazoles | 1990 |
Antigen induces leucopenia in non-immunised guinea-pigs injected with platelets from actively sensitized animals.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Azepines; Blood Platelets; Female; Guinea Pigs; Immunization; In Vitro Techniques; Indicators and Reagents; Indium Radioisotopes; Leukocyte Count; Leukopenia; Male; Nedocromil; Ovalbumin; Quinolones; Triazoles | 1990 |
IgG1-mediated acute pulmonary hypersensitivity response in the guinea pig. Involvement of specific lipid mediators.
Topics: Acute Disease; Animals; Azepines; Bronchoconstriction; Dicarboxylic Acids; Dose-Response Relationship, Drug; Furans; Guinea Pigs; Immunization; Immunoglobulin G; Indoles; Lipids; Lung; Male; Ovalbumin; Phenylcarbamates; Piroxicam; Platelet Activating Factor; Propranolol; Pyrilamine; Respiratory Hypersensitivity; SRS-A; Sulfonamides; Tosyl Compounds; Triazoles | 1990 |
Synthesis of peptide-immunogens corresponding to amino acid sequences from human histocompatibility class II membrane glycoproteins.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Antigens; Chemical Phenomena; Chemistry, Physical; Dicyclohexylcarbodiimide; Glycoproteins; Histocompatibility Antigens Class II; Immune Sera; Immunization; Molecular Sequence Data; Ovalbumin; Peptides; Rabbits; Triazoles | 1990 |
The booster injection of antigen during active sensitization of guinea-pig modifies the anti-anaphylactic activity of the PAF antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Azepines; Blood Cell Count; Bronchi; Enzyme-Linked Immunosorbent Assay; Guinea Pigs; Histamine; Immunization, Secondary; Immunoglobulin G; Lung; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; Spectrometry, Fluorescence; Thromboxane B2; Triazoles | 1990 |
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles | 1989 |
Effect of a Paf antagonist, WEB 2086, on airway microvascular leakage in the guinea-pig and platelet aggregation in man.
Topics: Adenosine Diphosphate; Animals; Azepines; Capillary Permeability; Guinea Pigs; Humans; In Vitro Techniques; Male; Ovalbumin; Platelet Activating Factor; Platelet Aggregation; Triazines; Triazoles | 1988 |
Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis.
Topics: Administration, Oral; Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Immunization; Immunization, Passive; Injections, Intravenous; Male; Mice; Ovalbumin; Platelet Activating Factor; Pyrilamine; Respiration; Triazines; Triazoles | 1987 |
Studies with two new phosphodiesterase inhibitors (ICI 58, 301 and ICI 63, 197) on anaphylaxis in guinea pigs, mice and rats.
Topics: Acetamides; Anaphylaxis; Animals; Cyclic AMP; Freund's Adjuvant; Germ-Free Life; Guinea Pigs; Immune Sera; Immunoglobulin E; Lung; Mice; Ovalbumin; Passive Cutaneous Anaphylaxis; Pertussis Vaccine; Phosphodiesterase Inhibitors; Precipitins; Pyrazines; Pyrimidines; Rats; Triazoles | 1973 |
Antiallergic activity profiles in vitro of RHC 3164 and related compounds. I. A lack of correlation between inhibition of cyclic nucleotide phosphodiesterases and antigen-induced release of histamine from rat mast cells.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antibodies, Anti-Idiotypic; Antigens; Basophils; Cromolyn Sodium; Depression, Chemical; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E; Kinetics; Lung; Male; Mast Cells; Ovalbumin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains; Triazoles | 1984 |
Occurrence of disseminated intravascular coagulation (DIC) in active systemic anaphylaxis: role of platelet-activating factor.
Topics: Anaphylaxis; Animals; Azepines; Disseminated Intravascular Coagulation; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Triazoles | 1995 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles | 1994 |
Role of PAF in the allergic pleurisy caused by ovalbumin in actively sensitized rats.
Topics: Analysis of Variance; Animals; Azepines; Chemotactic Factors, Eosinophil; Diterpenes; Drug Hypersensitivity; Eosinophils; Female; Freund's Adjuvant; Ginkgolides; Inflammation; Lactones; Leukocyte Count; Male; Oligopeptides; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
Bronchopulmonary responses to endothelin-1 in sensitized and challenged guinea-pigs: role of cyclooxygenase metabolites and platelet-activating factor.
Topics: Aerosols; Animals; Azepines; Bronchi; Disease Models, Animal; Endothelins; Glycopeptides; Guinea Pigs; Immunization; Indomethacin; Lung; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1993 |
Involvement of platelet-activating factor in death following anaphylactic shock in boosted and in unboosted mice.
Topics: Anaphylaxis; Animals; Azepines; Immunization, Secondary; Immunoglobulin E; Immunoglobulin G; Male; Mice; Ovalbumin; Platelet Activating Factor; Triazoles; Vaccination | 1993 |
Pharmacological characterisation of a new model of antigen-induced pulmonary late-phase reaction in the conscious guinea pig which uses additional polymyxin B inhalation.
Topics: Administration, Inhalation; Animals; Anti-Bacterial Agents; Antigens; Asthma; Azepines; Disease Models, Animal; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity, Delayed; Male; Ovalbumin; Polymyxin B; Pyrilamine; Triazoles | 1996 |
Suppressive effects of Y-24180, a receptor antagonist to platelet activating factor (PAF), on antigen-induced asthmatic responses in guinea pigs.
Topics: Administration, Oral; Aerosols; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Chromones; Enzyme Inhibitors; Guinea Pigs; Heptanoic Acids; Histamine Antagonists; Leukotriene Antagonists; Male; Methacrylates; Ovalbumin; Platelet Membrane Glycoproteins; Pyrilamine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine Proteinase Inhibitors; Signal Transduction; Theophylline; Thromboxane-A Synthase; Triazoles | 1997 |
Apafant (a PAF receptor antagonist) suppresses the early and late airway responses in guinea pigs: a comparison with antiasthmatic drugs.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Airway Resistance; Albuterol; Animals; Anti-Asthmatic Agents; Azepines; Bronchodilator Agents; Cromolyn Sodium; Dexamethasone; Drug Interactions; Glucocorticoids; Guinea Pigs; Histamine Antagonists; Histamine H1 Antagonists; Methacrylates; Metyrapone; Ovalbumin; Platelet Aggregation Inhibitors; Plethysmography; Pyrilamine; Theophylline; Thromboxane-A Synthase; Triazoles; Vaccination | 1997 |
TAK-603 selectively suppresses Th1-type cytokine production and inhibits the progression of adjuvant arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Cell Culture Techniques; Cytokines; Dose-Response Relationship, Drug; Gene Expression; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Ovalbumin; Quinolines; Rats; Rats, Inbred Lew; RNA, Messenger; Th1 Cells; Triazoles | 1997 |
Anaphylaxis-induced mesenteric vascular permeability, granulocyte adhesion, and platelet aggregates in rat.
Topics: Albuterol; Anaphylaxis; Animals; Azepines; Capillary Permeability; Cell Adhesion; Diphenhydramine; Granulocytes; Immunoglobulin E; Indomethacin; Mast Cells; Methysergide; Microscopy, Video; Ovalbumin; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Serum Albumin, Bovine; Splanchnic Circulation; Time Factors; Triazoles; Venules | 1998 |
Effects of the platelet activating factor antagonists BN 52021 and BN 50730 on antigen-induced bronchial hyperresponsiveness and eosinophil infiltration in lung from sensitized guinea-pigs.
Topics: Acetylcholine; Aerosols; Animals; Azepines; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Diterpenes; Eosinophilia; Ginkgo biloba; Ginkgolides; Guinea Pigs; Lactones; Leukotriene B4; Lung Diseases; Male; Molecular Structure; Ovalbumin; Plants, Medicinal; Platelet Activating Factor; Specific Pathogen-Free Organisms; Thienopyridines; Triazoles | 1993 |
Effect of Y-24180, a receptor antagonist to platelet-activating factor (PAF), on allergic cutaneous reactions in actively sensitized mice.
Topics: Administration, Oral; Administration, Topical; Allergens; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Arylsulfonates; Azepines; Dermatitis, Allergic Contact; Ear; Eosinophils; Histamine H1 Antagonists; Hydrocortisone; Immunoglobulin E; Immunoglobulin G; Ketotifen; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Ovalbumin; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sulfonium Compounds; Time Factors; Triazoles | 2000 |
A3 receptors mediate rapid inflammatory cell influx into the lungs of sensitized guinea-pigs.
Topics: Adenosine Monophosphate; Animals; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Leukocyte Count; Leukocytes; Lung; Male; Ovalbumin; Pneumonia; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles | 2001 |
Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat.
Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Blood Pressure; Budesonide; Dose-Response Relationship, Drug; Inflammation; Lung; Male; Ovalbumin; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred BN; Receptor, Adenosine A2A; Triazines; Triazoles; Vascular Resistance | 2002 |
The pharmacological profile of ovalbumin-induced paw oedema in rats.
Topics: Animals; Anti-Allergic Agents; Azepines; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Immunologic; Edema; Enzyme Inhibitors; Foot; Histamine H1 Antagonists; Hypersensitivity; Immunization; Immunosuppressive Agents; Ketotifen; Ovalbumin; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles | 2002 |
A small molecule inhibitor of redox-regulated NF-kappa B and activator protein-1 transcription blocks allergic airway inflammation in a mouse asthma model.
Topics: Administration, Intranasal; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Movement; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Eosinophils; Female; Humans; Inflammation; Interleukin-13; Lung; Mice; Mice, Inbred BALB C; Mucus; NF-kappa B; Ovalbumin; Oxidation-Reduction; Pyridazines; Thioredoxins; Transcription Factor AP-1; Triazoles; Tumor Cells, Cultured | 2002 |
Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs.
Topics: Administration, Topical; Animals; Azepines; Chronic Disease; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Drug; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Male; Ophthalmic Solutions; Ovalbumin; Platelet Activating Factor; Tears; Triazoles | 2004 |
Inhibition of anaphylaxis like reaction and mast cell activation by Sitagliptin.
Topics: Anaphylaxis; Animals; Cytokines; Dose-Response Relationship, Drug; Histamine Release; Hypersensitivity; Immunoglobulin E; Male; Mast Cells; Mice; Ovalbumin; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Pyrazines; Rats; Rats, Wistar; Sitagliptin Phosphate; Triazoles; Tumor Necrosis Factor-alpha | 2011 |
Sitagliptin exerts anti-inflammatory and anti-allergic effects in ovalbumin-induced murine model of allergic airway disease.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Inflammation; Lung; Male; Mice; Nitric Oxide Synthase Type II; Ovalbumin; Pyrazines; RNA, Messenger; Sitagliptin Phosphate; Triazoles | 2012 |
Design, Synthesis, and Evaluation of Novel 1,2,3-Triazole-Tethered Glycolipids as Vaccine Adjuvants.
Topics: Adjuvants, Immunologic; Alum Compounds; Animals; B-Lymphocytes; Cell Proliferation; Cells, Cultured; Drug Design; Glycolipids; Hemolysis; Immunization; Immunoglobulin G; Interferon-gamma; Interleukin-12; Lymphocyte Activation; Male; Mice, Inbred BALB C; Molecular Structure; Ovalbumin; Rats, Wistar; Structure-Activity Relationship; Th1 Cells; Triazoles; Tumor Necrosis Factor-alpha | 2015 |
Boosting Adaptive Immunity: A New Role for PAFR Antagonists.
Topics: Adaptive Immunity; Animals; Azepines; CD4-Positive T-Lymphocytes; Cells, Cultured; Dendritic Cells; Freund's Adjuvant; Immunization; Immunoglobulin G; Mice; Ovalbumin; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Spleen; Triazoles | 2016 |
[Mechanism of action of BET bromodomain inhibitor JQ1 in treating airway remodeling in asthmatic mice].
Topics: Airway Remodeling; Animals; Asthma; Azepines; Cadherins; Epithelial-Mesenchymal Transition; Female; Mice; Nuclear Proteins; Ovalbumin; RNA, Messenger; Transcription Factors; Triazoles; Vimentin | 2017 |
Unveiling novel diphenyl-1H-pyrazole based acrylates tethered to 1,2,3-triazole as promising apoptosis inducing cytotoxic and anti-inflammatory agents.
Topics: Acrylates; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Cell Membrane; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Erythrocytes; Humans; Molecular Docking Simulation; Molecular Structure; Ovalbumin; Protein Denaturation; Serum Albumin, Bovine; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2019 |
Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes.
Topics: ADP-Ribosylation Factor 6; Animals; Asthma; CARD Signaling Adaptor Proteins; Cell Communication; Disease Models, Animal; Humans; Inflammasomes; Interleukin-1beta; Lung; Macrophages, Alveolar; Mice; Mice, Knockout; Ovalbumin; Phagocytosis; Symptom Flare Up; Th2 Cells; THP-1 Cells; Triazoles | 2021 |
Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Dipeptides; Mice; Ovalbumin; Triazoles | 2022 |