Page last updated: 2024-08-24

triazoles and organophosphonates

triazoles has been researched along with organophosphonates in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.35)18.7374
1990's1 (2.17)18.2507
2000's7 (15.22)29.6817
2010's33 (71.74)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Eichmann, T; Krempien, B; Manegold, C; Wingen, F1
Fuertes, M; Robins, RK; Streeter, DG; Witkowski, JT1
Guyer, D; Hatano, M; Nakayama, Y; Ohta, D; Tada, S; Volrath, S; Ward, E1
McClellan, MB1
Bernal, J; Bernal, JL; del Nozal, MJ; Jiménez, JJ; Toribio, L1
Akhtar, S; Benter, IF; Canatan, H; Yousif, MH1
Holý, A; Kmonícková, E; Potmesil, P; Zídek, Z1
Holý, A; Kmonícková, E; Krecmerová, M; Potmesil, P; Zídek, Z1
Abel, S; Muirhead, GJ; Ridgway, CE; Russell, D; Whitlock, LA1
Akbey, U; Bozkurt, A; Celik, SU; Graf, R; Spiess, HW1
Ganesan, M; Muraleedharan, KM1
Curto, J; Niubo, J; Podzamczer, D; Tiraboschi, JM1
Elayadi, H; Lazrek, HB; Leyssen, P; Neyts, J; Pannecouque, C; Smietana, M; Vasseur, JJ1
Kaptur, PE; Mertenskoetter, T1
Férir, G; Palmer, KE; Schols, D1
Chaiken, I; Fletcher, P; Gopi, H; Krebs, FC; Martin-Garcia, J; McFadden, K; Pirrone, V; Rajagopal, S; Rossi, F; Shattock, RJ; Umashankara, M1
Attwood, PV; Besant, PG; Byrne, LT; Flematti, GR; Mukai, S; Piggott, MJ1
Back, DJ; Else, LJ; Khoo, SH; Taylor, S1
Fang, J; Jadhav, PR1
Acosta, EP; Barreca, ML; Chirullo, B; Collins, M; Della Corte, A; Greenhouse, J; Iraci, N; Lewis, MG; Norelli, S; Savarino, A; Shytaj, IL; Yalley-Ogunro, J1
Dai, CC; Ren, CG1
Strohmeier, M; Vogt, FG1
Craig, C; Fätkenheuer, G; Heera, J; Leal, M; McFadyen, L; Mildvan, D; Mills, A; Podzamczer, D; Portsmouth, S; Rinehart, AR; Than, S; Valdez, H; Valluri, SR; Vourvahis, M1
Bennett, LJ; Grooms-Williams, TW; Hamorsky, KT; Husk, AS; Matoba, N; Palmer, KE1
Feucht, N; Hadeler, J; Lanzl, I; Loos, D; Schmid, RM; Schwerdtfeger, C; Spinner, CD1
Binet, L; Djerada, Z; Feliu, C; Gozalo, C; Lamiable, D; Marty, H; Millart, H; Robinet, A; Tournois, C; Vautier, D1
Fan, X; Hao, G; Li, L; Zhang, G; Zhang, L; Zhu, A1
McGowan, I1
Balzarini, J; Głowacka, IE; Wróblewski, AE1
Balzarini, J; Głowacka, IE; Piotrowska, DG1
Andrei, G; Balzarini, J; Głowacka, IE; Piotrowska, DG; Schols, D; Snoeck, R1
Achhra, AC; Boyd, MA; Cooper, DA; Kelleher, AD; Law, MG; Matthews, GV1
Akkina, R; Kashuba, ADM; LeCureux, J; Remling-Mulder, L; Sykes, C; Veselinovic, M; Yang, KH1
Abdou, WM; Ganoub, NA; Sabry, E1
Cohen, MS; Emerson, CW; Fedoriw, Y; Geller, EJ; Kashuba, AD; Nelson, JA; Nicol, MR; Patterson, KB; Prince, HM; Sykes, C1
De La Mata, FJ; Gómez, R; Jiménez, JL; Muñoz-Fernández, MÁ; Sánchez-Rodríguez, J; Sepúlveda-Crespo, D; Serramía, MJ1
Andrei, G; Głowacka, IE; Piotrowska, DG; Schols, D; Snoeck, R1
Andrei, G; Engels, JW; Lazrek, HB; Ouahrouch, A; Schols, D; Snoeck, R; Taourirte, M1
Abdul Salam, AA; Das, S; Kamath, PR; Rao, BS; Sunil, D1
Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY1
Aparicio, VC; Costa, JL; De Gerónimo, E; Menone, ML; Okada, E; Pérez, DJ1
Chen, Y; Jiang, C; Li, Z; Lin, T; Liu, Y; Sun, H; Yang, D1
Baptista, MS; Bastos, MM; Boechat, N; Cafffarena, ER; Costa, CCP; da Silva, FC; Hoelz, LVB; Marttorelli, A; Souza, TML1
Bálint, E; Hackler, L; Kari, B; Puskás, LG; Szabó, PT; Tóth, E; Tripolszky, A1
Bouzat, C; Nielsen, BE; Stabile, S; Vitale, C1
Gao, Z; Gou, J; Wahab, A; Yu, B1

Reviews

3 review(s) available for triazoles and organophosphonates

ArticleYear
Update on microbicide research and development - seeking new HIV prevention tools for women.
    European journal of medical research, 2011, Jan-27, Volume: 16, Issue:1

    Topics: Adenine; Administration, Intravaginal; Adult; Africa South of the Sahara; Anti-HIV Agents; Anti-Infective Agents; Clinical Trials as Topic; Cyclohexanes; Drug Discovery; Female; HIV Infections; Humans; Male; Maraviroc; Organophosphonates; Pyridines; Pyrimidines; Tenofovir; Triazoles; Urea

2011
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Adenine; Adult; Amniotic Fluid; Anti-HIV Agents; Cyclohexanes; Enfuvirtide; Female; Fetal Blood; Fetus; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Maraviroc; Nevirapine; Organophosphonates; Peptide Fragments; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Viral Load; Zidovudine

2011
An overview of antiretroviral pre-exposure prophylaxis of HIV infection.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2014, Volume: 71, Issue:6

    Topics: Adenine; Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; Female; HIV Infections; Humans; Male; Maraviroc; Medication Adherence; Nitriles; Organophosphonates; Pre-Exposure Prophylaxis; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Triazoles

2014

Trials

3 trial(s) available for triazoles and organophosphonates

ArticleYear
The effects of cotrimoxazole or tenofovir co-administration on the pharmacokinetics of maraviroc in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Anti-Infective Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Organophosphonates; Receptors, CCR5; Statistics as Topic; Tenofovir; Triazoles; Trimethoprim, Sulfamethoxazole Drug Combination

2008
From in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part I: a framework.
    Journal of pharmacokinetics and pharmacodynamics, 2012, Volume: 39, Issue:4

    Topics: Adenine; Anti-HIV Agents; Cyclohexanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Male; Maraviroc; Models, Biological; Nitriles; Organophosphonates; Oxazines; Piperazines; Pyridazines; Pyridones; Pyrimidines; RNA, Viral; Tenofovir; Triazoles

2012
Maraviroc once-daily nucleoside analog-sparing regimen in treatment-naive patients: randomized, open-label pilot study.
    Journal of acquired immune deficiency syndromes (1999), 2013, Feb-01, Volume: 62, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Atazanavir Sulfate; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Oligopeptides; Organophosphonates; Pilot Projects; Pyridines; Ritonavir; RNA, Viral; Tenofovir; Triazoles; Viral Load; Young Adult

2013

Other Studies

40 other study(ies) available for triazoles and organophosphonates

ArticleYear
Effects of new bisphosphonic acids on tumor-induced bone destruction in the rat.
    Journal of cancer research and clinical oncology, 1986, Volume: 111, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma 256, Walker; Diphosphonates; Male; Organophosphonates; Organophosphorus Compounds; Pamidronate; Rats; Time Factors; Triazoles

1986
Synthesis and enzymatic activity of 1,2,4-triazole-3-carboxamide 6'-deoxyhomoribonucleoside-6'-phosphonic acid and related compounds.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:6

    Topics: Escherichia coli; Inosine Nucleotides; Magnetic Resonance Spectroscopy; Organophosphonates; Oxidoreductases; Ribonucleotides; Structure-Activity Relationship; Triazoles

1974
Insect cell expression of recombinant imidazoleglycerolphosphate dehydratase of Arabidopsis and wheat and inhibition by triazole herbicides.
    Plant physiology, 1995, Volume: 109, Issue:1

    Topics: Amino Acid Sequence; Amitrole; Animals; Arabidopsis; Baculoviridae; Base Sequence; Cell Line; DNA, Plant; Enzyme Inhibitors; Gene Expression; Herbicides; Hydro-Lyases; Kinetics; Molecular Sequence Data; Organophosphonates; Recombinant Proteins; Spodoptera; Triazines; Triazoles; Triticum

1995
From the Food and Drug Administration.
    JAMA, 2002, Nov-06, Volume: 288, Issue:17

    Topics: Adenine; Anastrozole; Antineoplastic Agents, Hormonal; Antiviral Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Hepatitis B, Chronic; Humans; Nitriles; Organophosphonates; Triazoles; United States; United States Food and Drug Administration

2002
Determination of impurities in pesticides and their degradation products formed during the wine-making process by solid-phase extraction and gas chromatography with detection by electron ionization mass spectrometry. II. Bromopropylate, trichlorphon, para
    Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:22

    Topics: Benzilates; Food Contamination; Gas Chromatography-Mass Spectrometry; Methyl Parathion; Organophosphonates; Pesticide Residues; Spectrometry, Mass, Electrospray Ionization; Triazoles; Wine

2004
Inhibition of Ca2+/calmodulin-dependent protein kinase II, RAS-GTPase and 20-hydroxyeicosatetraenoic acid attenuates the development of diabetes-induced vascular dysfunction in the rat carotid artery.
    Pharmacological research, 2005, Volume: 52, Issue:3

    Topics: Amidines; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carotid Arteries; Carotid Artery Diseases; Diabetes Mellitus, Experimental; Hydroxyeicosatetraenoic Acids; Monomeric GTP-Binding Proteins; Organophosphonates; Protein Kinase Inhibitors; Rats; Rats, Wistar; Streptozocin; Sulfonamides; Triazoles; Vascular Diseases; Vasoconstriction; Vasodilation

2005
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: 2-Aminopurine; Adenine; Adjuvants, Immunologic; Animals; Anti-HIV Agents; Caffeine; Cell Survival; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Dihydropyridines; Dose-Response Relationship, Drug; Female; Flavins; Humans; Interleukin-10; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Organophosphonates; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Triazoles; Tumor Necrosis Factor-alpha

2006
Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives.
    European journal of pharmacology, 2006, Jul-01, Volume: 540, Issue:1-3

    Topics: Adenine; Animals; Caffeine; Cell Survival; Cytokines; Dihydropyridines; Dose-Response Relationship, Drug; Female; Gene Expression; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Nucleotides; Organophosphonates; Organophosphorus Compounds; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles

2006
Anhydrous proton-conducting properties of triazole-phosphonic acid copolymers: a combined study with MAS NMR.
    Physical chemistry chemical physics : PCCP, 2008, Oct-21, Volume: 10, Issue:39

    Topics: Carbon Isotopes; Electric Conductivity; Electrolytes; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Molecular Weight; Organophosphonates; Phosphorus Isotopes; Polymers; Protons; Reference Standards; Temperature; Triazoles; Vinyl Compounds

2008
Synthesis of beta-hydroxyphosphonate and 1,2-dihydroxy acyclic nucleoside analogs via 1,3-dipolar cycloaddition strategy.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:2

    Topics: Chemistry, Organic; Crystallography, X-Ray; Cyclization; Nucleic Acid Conformation; Nucleosides; Organophosphonates; Propylene Glycols; Purines; Pyrimidines; Triazoles

2010
Maraviroc concentrations in cerebrospinal fluid in HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Chromatography, Liquid; Cyclohexanes; Didanosine; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Tandem Mass Spectrometry; Tenofovir; Triazoles; Viral Load

2010
Straightforward synthesis of triazoloacyclonucleotide phosphonates as potential HCV inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Alkynes; Antiviral Agents; Azides; Catalysis; Cell Line, Tumor; Copper; Hepacivirus; Humans; Nucleotides; Organophosphonates; Structure-Activity Relationship; Triazoles; Virus Replication

2010
Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C.
    Virology, 2011, Sep-01, Volume: 417, Issue:2

    Topics: Adenine; Algal Proteins; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclohexanes; Drug Synergism; Enfuvirtide; Genotype; HIV Envelope Protein gp41; HIV-1; Humans; Lectins; Leukocytes, Mononuclear; Maraviroc; Microbial Sensitivity Tests; Organophosphonates; Peptide Fragments; Plant Lectins; Tenofovir; Triazoles

2011
Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Adenine; Anti-HIV Agents; Cell Line; Drug Therapy, Combination; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV-1; Humans; Organophosphonates; Peptides; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Virus Replication

2012
Stable triazolylphosphonate analogues of phosphohistidine.
    Amino acids, 2012, Volume: 43, Issue:2

    Topics: Alanine; Amino Acids; Catalysis; Chromatography, High Pressure Liquid; Click Chemistry; Copper; Fluorenes; Haptens; Histidine; Organophosphonates; Stereoisomerism; Triazoles

2012
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model.
    PLoS pathogens, 2012, Volume: 8, Issue:6

    Topics: Adenine; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Darunavir; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Flow Cytometry; Fluorescent Antibody Technique; Macaca mulatta; Maraviroc; Organophosphonates; Pyrrolidinones; Raltegravir Potassium; Ritonavir; Simian Acquired Immunodeficiency Syndrome; Sulfonamides; T-Lymphocyte Subsets; Tenofovir; Triazoles; Viral Load; Viremia

2012
Jasmonic acid is involved in the signaling pathway for fungal endophyte-induced volatile oil accumulation of Atractylodes lancea plantlets.
    BMC plant biology, 2012, Aug-02, Volume: 12

    Topics: Antioxidants; Atractylodes; Benzoates; Catalase; Cyclopentanes; Endophytes; Enzyme Inhibitors; Free Radical Scavengers; Fungi; Hydrogen Peroxide; Imidazoles; Indans; Masoprocol; Nitric Oxide; Oils, Volatile; Onium Compounds; Organophosphonates; Oxylipins; Plant Diseases; Plants, Medicinal; Salicylic Acid; Signal Transduction; Time Factors; Triazoles

2012
2D solid-state NMR analysis of inclusion in drug-cyclodextrin complexes.
    Molecular pharmaceutics, 2012, Nov-05, Volume: 9, Issue:11

    Topics: Adenine; Carbon Radioisotopes; Cyclodextrins; Diflunisal; Fluorine Radioisotopes; Hydrogen; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organophosphonates; Phosphorus; Pyrimidines; Triazoles; Voriconazole

2012
Efficient single tobamoviral vector-based bioproduction of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 in Nicotiana benthamiana plants and utility of VRC01 in combination microbicides.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:5

    Topics: Adenine; Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antiviral Agents; Chromatography, Affinity; Cyclohexanes; Drug Combinations; Drug Synergism; Genetic Vectors; HIV Antibodies; HIV Envelope Protein gp120; HIV-1; Humans; Immunoglobulin G; Maraviroc; Neutralization Tests; Nicotiana; Organophosphonates; Plant Lectins; Recombinant Proteins; Tenofovir; Tobamovirus; Triazoles

2013
[Ophthalmological alterations at the initial diagnosis of HIV infection].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2014, Volume: 111, Issue:7

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Cyclohexanes; Deoxycytidine; Drug Therapy, Combination; Early Diagnosis; Emtricitabine; Eye Infections, Viral; HIV Infections; Humans; Lopinavir; Male; Maraviroc; Organophosphonates; Retinal Diseases; Syndrome; Tenofovir; Treatment Outcome; Triazoles; Zidovudine

2014
Validation of a fast method for quantitative analysis of elvitegravir, raltegravir, maraviroc, etravirine, tenofovir, boceprevir and 10 other antiretroviral agents in human plasma samples with a new UPLC-MS/MS technology.
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 86

    Topics: Adenine; Anti-Retroviral Agents; Chromatography, High Pressure Liquid; Cyclohexanes; Humans; Maraviroc; Mass Spectrometry; Nitriles; Organophosphonates; Proline; Pyridazines; Pyrimidines; Pyrrolidinones; Quinolones; Raltegravir Potassium; Tandem Mass Spectrometry; Tenofovir; Time Factors; Triazoles

2013
A copper(I)-catalyzed three-component domino process: assembly of complex 1,2,3-triazolyl-5-phosphonates from azides, alkynes, and H-phosphates.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Oct-18, Volume: 19, Issue:43

    Topics: Alkynes; Azides; Catalysis; Copper; Hydrogen; Organophosphonates; Oxidation-Reduction; Phosphates; Triazoles

2013
Novel acyclic phosphonylated 1,2,3-triazolonucleosides with an acetamidomethyl linker: synthesis and biological activity.
    Archiv der Pharmazie, 2014, Volume: 347, Issue:7

    Topics: Acetamides; Animals; Antineoplastic Agents; Antiviral Agents; Cats; Cell Line; Cell Survival; Cycloaddition Reaction; Cytopathogenic Effect, Viral; DNA Viruses; HeLa Cells; Humans; Molecular Structure; Nucleotides; Organophosphonates; RNA Viruses; Triazoles

2014
1-Amino-3-(1H-1,2,3-triazol-1-yl)propylphosphonates as acyclic analogs of nucleotides.
    Archiv der Pharmazie, 2014, Volume: 347, Issue:7

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cats; Cell Line; Cell Proliferation; Cell Survival; Cycloaddition Reaction; Cytopathogenic Effect, Viral; DNA Viruses; HeLa Cells; Humans; Mice; Molecular Structure; Nucleotides; Organophosphonates; RNA Viruses; Structure-Activity Relationship; T-Lymphocytes; Triazoles

2014
Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues.
    Bioorganic & medicinal chemistry, 2014, Jul-15, Volume: 22, Issue:14

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Proliferation; Cell Survival; Cytostatic Agents; DNA Viruses; Dogs; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Organophosphonates; RNA Viruses; Structure-Activity Relationship; T-Lymphocytes; Triazoles

2014
Moving away from Ritonavir, Abacavir, Tenofovir, and Efavirenz (RATE)--agents that concern prescribers and patients: a feasibility study and call for a trial.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclohexanes; Cyclopropanes; Dideoxynucleosides; Feasibility Studies; Female; Humans; Male; Maraviroc; Middle Aged; Organophosphonates; Ritonavir; Tenofovir; Triazoles

2014
HIV pre-exposure prophylaxis: mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model.
    Virology, 2014, Volume: 464-465

    Topics: Adenine; Animals; Anti-HIV Agents; Cyclohexanes; Disease Models, Animal; Female; HIV Infections; HIV-1; Humans; Maraviroc; Mice; Mucous Membrane; Organophosphonates; Pre-Exposure Prophylaxis; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Virus Internalization

2014
Design, synthesis and pharmacological screening of β-amino-, thiadiazole/thiadiazine-phosphonate based triazole motifs as antimicrobial/cytotoxic agents.
    Acta pharmaceutica (Zagreb, Croatia), 2014, Volume: 64, Issue:3

    Topics: Anti-Infective Agents; Antineoplastic Agents; Cell Survival; Computer-Aided Design; Dose-Response Relationship, Drug; Drug Design; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Inhibitory Concentration 50; Male; MCF-7 Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Neoplasms; Organophosphonates; Structure-Activity Relationship; Thiadiazines; Thiadiazoles; Triazoles

2014
Models for predicting effective HIV chemoprevention in women.
    Journal of acquired immune deficiency syndromes (1999), 2015, Apr-01, Volume: 68, Issue:4

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Cell Culture Techniques; Cell Survival; Chemoprevention; Chromatography, Liquid; Cyclohexanes; Disease Transmission, Infectious; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Maraviroc; Middle Aged; Organ Culture Techniques; Organophosphonates; Tandem Mass Spectrometry; Tenofovir; Triazoles; Vagina; Viral Load; Young Adult

2015
Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission.
    Nanomedicine (London, England), 2015, Volume: 10, Issue:6

    Topics: Adenine; Animals; Anti-HIV Agents; Anti-Infective Agents; Antiviral Agents; Cell Survival; Cyclohexanes; Dendrimers; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Maraviroc; Mice; Mice, Inbred BALB C; Mucous Membrane; Organophosphonates; Silanes; Software; Tenofovir; Triazoles; Vagina

2015
Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker.
    Molecules (Basel, Switzerland), 2015, Oct-16, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Chlorocebus aethiops; DNA Viruses; Dogs; Drug Screening Assays, Antitumor; Guanosine; HeLa Cells; Humans; Inhibitory Concentration 50; Madin Darby Canine Kidney Cells; Organophosphonates; RNA Viruses; Triazoles; Vero Cells

2015
Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3-Triazolylbenzyl-aminophosphonates.
    Archiv der Pharmazie, 2016, Volume: 349, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Crystallography, X-Ray; DNA Viruses; Humans; Organophosphonates; Ribonucleosides; RNA Viruses; Structure-Activity Relationship; Triazoles

2016
Efficient T3P
    Chemico-biological interactions, 2017, Apr-25, Volume: 268

    Topics: Adenocarcinoma; Anhydrides; Antineoplastic Agents; Apoptosis; bcl-X Protein; Breast Neoplasms; DNA Fragmentation; Female; G1 Phase Cell Cycle Checkpoints; Green Chemistry Technology; Humans; Indoles; Ligands; MCF-7 Cells; Molecular Docking Simulation; Organophosphonates; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Thiadiazoles; Triazoles

2017
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:5

    Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles

2017
Spatial and temporal trends and flow dynamics of glyphosate and other pesticides within an agricultural watershed in Argentina.
    Environmental toxicology and chemistry, 2017, Volume: 36, Issue:12

    Topics: Argentina; Atrazine; Crops, Agricultural; Environmental Monitoring; Geologic Sediments; Glycine; Glyphosate; Herbicides; Isoxazoles; Neonicotinoids; Nitro Compounds; Organophosphonates; Pesticides; Rain; Rivers; Tetrazoles; Triazoles; Water Movements; Water Pollutants, Chemical

2017
Identification of novel and selective non-peptide inhibitors targeting the polo-box domain of polo-like kinase 1.
    Bioorganic chemistry, 2018, Volume: 81

    Topics: Binding Sites; Cell Cycle Proteins; Humans; Molecular Docking Simulation; Organophosphonates; Polo-Like Kinase 1; Protein Domains; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Triazoles

2018
New Efavirenz Derivatives and 1,2,3-Triazolyl-phosphonates as Inhibitors of Reverse Transcriptase of HIV-1.
    Current topics in medicinal chemistry, 2018, Volume: 18, Issue:17

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dose-Response Relationship, Drug; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles

2018
Synthesis and In Vitro Cytotoxicity and Antibacterial Activity of Novel 1,2,3-Triazol-5-yl-phosphonates.
    Molecules (Basel, Switzerland), 2020, Jun-06, Volume: 25, Issue:11

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Humans; Neoplasms; Organophosphonates; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2020
Design, Synthesis, and Functional Evaluation of a Novel Series of Phosphonate-Functionalized 1,2,3-Triazoles as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors.
    ACS chemical neuroscience, 2020, 09-02, Volume: 11, Issue:17

    Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Organophosphonates; Patch-Clamp Techniques; Receptors, Nicotinic; Triazoles

2020
The construction of phosphonate triazolyl by copper(II)-catalyzed furan dearomatized [3 + 2] cycloaddition.
    Organic & biomolecular chemistry, 2022, 08-17, Volume: 20, Issue:32

    Topics: Alkynes; Catalysis; Copper; Cycloaddition Reaction; Furans; Organophosphonates; Triazoles

2022