Page last updated: 2024-08-24

triazoles and oligonucleotides

triazoles has been researched along with oligonucleotides in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199011 (19.64)18.7374
1990's0 (0.00)18.2507
2000's13 (23.21)29.6817
2010's30 (53.57)24.3611
2020's2 (3.57)2.80

Authors

AuthorsStudies
Itakura, K; Katagiri, N; Narang, SA1
de Vroom, E; Dreef, CE; Marugg, JE; Tromp, M; van Boom, JH; van der Marel, GA1
Kanda, N; Maikuma, S; Shimidzu, T; Yamana, K1
Marugg, JE; Tromp, M; van Boom, JH; van den Bergh, C; van der Marel, GA; van Zoest, WJ1
Altona, C; Berendsen, RG; de Bruin, SH; Haasnoot, CA; Hilbers, CW; Mellema, JR; van Boeckel, CA; van Boom, JH; van der Marel, GA; Westerink, H1
Knorre, DG; Zarytova, VF1
van Boeckel, CA; van Boom, JH; van der Marel, GA; Wille, G1
Itakura, K; Miyoshi, K1
Reese, CB; Ubasawa, A1
Sung, WL1
Arentzen, R; Broka, C; Hozumi, T; Itakura, K1
Fruk, L; Graham, D; Grondin, A; Smith, WE1
Johnson, AA; Marchand, C; Pommier, Y1
Chidsey, CE; Collman, JP; Devaraj, NK; Ebina, W; Kakaradov, B; Kool, ET; Miller, GP1
Filichev, VV; Géci, I; Pedersen, EB1
Böhme, D; Düpre, N; Megger, DA; Müller, J1
Fujino, T; Marine, G; Nakamura, E1
Ichikawa, S; Matsuda, A; Nakane, M1
Iyer, RP1
Fujino, T; Guillot-Nieckowski, M; Isobe, H; Nakamura, E; Yamazaki, N1
Enderlin, G; Nielsen, P1
Chittepu, P; Seela, F; Sirivolu, VR1
Brown, T; El-Sagheer, AH1
Hari, Y; Imanishi, T; Izawa, A; Kuboyama, T; Nakahara, M; Obika, S1
Elchinger, PH; Faugeras, PA; Lucas, R; Zerrouki, R1
Baral, B; Deobald, L; Guenther, DC; Hrdlicka, PJ; Kumar, P; Paszczynski, AJ; Sharma, PK; Østergaard, ME1
Akabane, M; Hari, Y; Kuboyama, T; Nakahara, M; Obika, S; Pang, J1
Chizhov, A; Florentiev, V; Varizhuk, A1
Andersen, NK; Døssing, H; Jensen, F; Nielsen, P; Vester, B1
Hrdlicka, PJ; Sau, SP1
Brown, T; Dallmann, A; Dehmel, L; El-Sagheer, AH; Ernsting, NP; Griesinger, C; Mügge, C1
Hrdlicka, PJ; Kaura, M; Kumar, P1
Bag, SS; Kundu, R; Matsumoto, K; Talukdar, S1
Chizhov, AO; Chuvilin, AN; Fisunov, GY; Florentiev, VL; Kaluzhny, DN; Novikov, RA; Pozmogova, GE; Smirnov, IP; Tatarinova, ON; Varizhuk, AM1
Hari, Y; Nakahara, M; Obika, S1
Andersen, NK; Enderlin, G; Hervé, G; Hornum, M; Kumar, P; Len, C; Nielsen, LJ; Nielsen, P; Sartori, G1
Granqvist, L; Virta, P1
Fujino, T; Isobe, H1
Desaulniers, JP; Efthymiou, TC; Peel, BJ1
Duan, Q; Lu, K; Ma, L; Zhao, D1
Fujino, T; Isobe, H; Kogashi, K; Mattarella, M; Okada, K; Sogawa, K; Suzuki, T; Yasumoto, K1
Hornum, M; Kumar, P; Nielsen, P; Podsiadly, P1
Fujino, T; Isobe, H; Kogashi, K; Okada, K; Sogawa, K; Suzuki, T; Yasumoto, KI1
Brown, T; El-Sagheer, AH; Shivalingam, A; Tyburn, AE1
Gładysz, M; Milecki, J; Nowak-Karnowska, J; Pasternak, A1
Alterman, JF; Haraszti, RA; Khvorova, A; Krishnamurthy, PM; Prasad, AK; Sharma, VK; Singh, SK; Watts, JK1
Brunschweiger, A; Hall, J; Lightfoot, HL; Malinowska, AL; Menzi, M; Pradère, U; Wild, B1
Brown, T; El-Sagheer, AH; Kumar, P; Truong, L1
Boland, BS; Vermeire, S1
Corey, DR; Damha, MJ; Li, L; Liu, Z; Norrbom, M; O'Reilly, D; Prakash, TP; Rigo, F; Sharma, VK; Shen, X; Watts, JK1
Armstrong, J; Butora, G; Copeland, G; Davies, IW; Gouker, J; Jadhav, V; Li, Z; Sherer, EC; Sidler, DR; Tellers, DM; Zewge, D1
Burley, GA; Hatit, MZC; Reichenbach, LF; Tobin, JM; Vilela, F; Watson, AJB1
Brown, T; El-Sagheer, AH; Shivalingam, A; Taemaitree, L1
Fujino, T; Ikemoto, K; Isobe, H; Ooi, T; Suzuki, T1
Abd El-Aty, AM; Chen, G; Cui, X; Du, P; Hacimüftüoğlu, A; Jiang, Z; Jin, M; Qin, G; Wang, J; Yan, F; Zhang, C; Zhang, Y1
Beal, PA; Lu, SS; Pham, KM; Suter, SR1

Reviews

3 review(s) available for triazoles and oligonucleotides

ArticleYear
HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial.
    Current topics in medicinal chemistry, 2004, Volume: 4, Issue:10

    Topics: Acetoacetates; Anti-HIV Agents; Biological Factors; Caffeic Acids; Clinical Trials as Topic; Furans; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Indoles; Models, Molecular; Molecular Structure; Oligonucleotides; Pyrroles; Reverse Transcriptase Inhibitors; Succinates; Tetrazoles; Triazoles

2004
Synthesis of triazole-nucleoside phosphoramidites and their use in solid-phase oligonucleotide synthesis.
    Current protocols in nucleic acid chemistry, 2014, Dec-19, Volume: 55

    Topics: Nucleosides; Oligonucleotides; Triazoles

2014
Janus Kinase Antagonists and Other Novel Small Molecules for the Treatment of Crohn's Disease.
    Gastroenterology clinics of North America, 2017, Volume: 46, Issue:3

    Topics: B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Humans; Indans; Janus Kinase 1; Janus Kinase Inhibitors; Oligonucleotides; Oxadiazoles; Piperidines; Pyridines; Pyrimidines; Pyrroles; Receptors, Lysosphingolipid; Smad7 Protein; T-Lymphocytes; Triazoles

2017

Other Studies

53 other study(ies) available for triazoles and oligonucleotides

ArticleYear
The use of arylsulfonyltriazoles for the synthesis of oligonucleotides by the triester approach.
    Journal of the American Chemical Society, 1975, Dec-10, Volume: 97, Issue:25

    Topics: Arylsulfonates; Esters; Methods; Oligonucleotides; Triazoles

1975
Synthesis of nucleic acid methylphosphonates via the 1-hydroxybenzotriazole phosphotriester approach.
    Nucleic acids research, 1986, Mar-11, Volume: 14, Issue:5

    Topics: Chemical Phenomena; Chemistry; Dinucleoside Phosphates; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleotides, Cyclic; Oligonucleotides; Organophosphorus Compounds; Phosphorylation; Stereoisomerism; Triazoles

1986
A simple and convenient synthesis of 3'-5'- or 2'-5'-linked oligoribonucleotide by polymerization of unprotected ribonucleoside using phosphorus tris-azole.
    Nucleic acids research, 1984, Apr-11, Volume: 12, Issue:7

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Indicators and Reagents; Oligonucleotides; Oligoribonucleotides; Phosphoric Diester Hydrolases; Phosphorylation; Ribonucleosides; Spleen; Triazoles

1984
Synthesis of phosphorothioate-containing DNA fragments by a modified hydroxybenzotriazole phosphotriester approach.
    Nucleic acids research, 1984, Dec-11, Volume: 12, Issue:23

    Topics: Chromatography, High Pressure Liquid; DNA; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Oligonucleotides; Organothiophosphates; Stereoisomerism; Structure-Activity Relationship; Triazoles

1984
Synthesis and conformational analysis of synthetic DNA fragments.
    Cold Spring Harbor symposia on quantitative biology, 1983, Volume: 47 Pt 1

    Topics: Base Sequence; DNA; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Triazoles

1983
General scheme of the phosphotriester condensation in the oligodeoxyribonucleotide synthesis with arylsulfonyl chlorides and arylsulfonyl azolides.
    Nucleic acids research, 1984, Feb-24, Volume: 12, Issue:4

    Topics: Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Oligonucleotides; Organophosphates; Organophosphorus Compounds; Structure-Activity Relationship; Sulfonic Acids; Tetrazoles; Triazoles

1984
A general method for the synthesis of 5'-monophosphates of DNA fragments via phosphotriester intermediates.
    Nucleic acids research, 1982, Apr-10, Volume: 10, Issue:7

    Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Oligonucleotides; Phosphorylation; Triazoles

1982
Solid-phase synthesis of polynucleotides: V. Synthesis of oligodeoxyribonucleotides by the phosphomonotriazolide method.
    Nucleic acids symposium series, 1980, Issue:7

    Topics: Base Sequence; Indicators and Reagents; Methods; Oligodeoxyribonucleotides; Oligonucleotides; Organophosphorus Compounds; Thymidine Monophosphate; Triazoles

1980
Nature of side-reactions in oligonucleotide synthesis involving arenesulphonyl derivatives of 3-nitro-1,2,4-triazole and related condensing agents.
    Nucleic acids symposium series, 1980, Issue:7

    Topics: Adenosine; Cytidine; Deoxyguanosine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methods; Oligonucleotides; Structure-Activity Relationship; Sulfones; Thymidine; Triazoles

1980
Synthesis of 4-triazolopyrimidinone nucleotide and its application in synthesis of 5-methylcytosine-containing oligodeoxyribonucleotides.
    Nucleic acids research, 1981, Nov-25, Volume: 9, Issue:22

    Topics: 5-Methylcytosine; Cytosine; Indicators and Reagents; Methods; Oligodeoxyribonucleotides; Oligonucleotides; Phosphorylation; Pyrimidinones; Triazoles

1981
Simplications in the synthesis of short oligonucleotide blocks.
    Nucleic acids research, 1980, Nov-25, Volume: 8, Issue:22

    Topics: Indicators and Reagents; Methods; Oligonucleotides; Organophosphorus Compounds; Structure-Activity Relationship; Triazoles

1980
A new approach to oligonucleotide labelling using Diels-Alder cycloadditions and detection by SERRS.
    Chemical communications (Cambridge, England), 2002, Sep-21, Issue:18

    Topics: Azo Compounds; Coloring Agents; Cyclization; DNA; Furans; Maleimides; Oligonucleotide Probes; Oligonucleotides; Scattering, Radiation; Spectrum Analysis, Raman; Surface Properties; Triazoles

2002
Chemoselective covalent coupling of oligonucleotide probes to self-assembled monolayers.
    Journal of the American Chemical Society, 2005, Jun-22, Volume: 127, Issue:24

    Topics: Amines; Copper; Oligonucleotide Probes; Oligonucleotides; Organometallic Compounds; Triazoles

2005
Stabilization of parallel triplexes by twisted intercalating nucleic acids (TINAs) incorporating 1,2,3-triazole units and prepared by microwave-accelerated click chemistry.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2007, Volume: 13, Issue:22

    Topics: Acridines; DNA; Intercalating Agents; Microwaves; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Spectrometry, Fluorescence; Triazoles

2007
Conformational change induced by metal-ion-binding to DNA containing the artificial 1,2,4-triazole nucleoside.
    Inorganic chemistry, 2007, Nov-26, Volume: 46, Issue:24

    Topics: Adenine; DNA; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Silver; Temperature; Thymine; Triazoles

2007
Synthesis of an artificial oligonucleotide an efficient cycloaddition reaction.
    Nucleic acids symposium series (2004), 2007, Issue:51

    Topics: Acetylene; Azides; Biochemistry; Oligonucleotides; Triazoles

2007
Triazole-linked dumbbell oligodeoxynucleotides with NF-kappaB binding ability as potential decoy molecules.
    The Journal of organic chemistry, 2008, Mar-07, Volume: 73, Issue:5

    Topics: Base Sequence; Magnetic Resonance Spectroscopy; NF-kappa B; Oligonucleotides; Protein Binding; Spectrometry, Mass, Fast Atom Bombardment; Triazoles

2008
Nucleobase protection of deoxyribo- and ribonucleosides.
    Current protocols in nucleic acid chemistry, 2001, Volume: Chapter 2

    Topics: Biochemistry; Deoxyribonucleosides; Hydrogen-Ion Concentration; Imides; Isomerism; Lactams; Oligonucleotides; Purines; Ribonucleosides; Triazoles

2001
Triazole-linked analogue of deoxyribonucleic acid ((TL)DNA): design, synthesis, and double-strand formation with natural DNA.
    Organic letters, 2008, Sep-04, Volume: 10, Issue:17

    Topics: Copper; Cyclization; DNA; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Thymine; Triazoles

2008
Synthesis of 6'-branched locked nucleic acid by a radical TEMPO-scavanged stereoselective mercury cyclization.
    The Journal of organic chemistry, 2008, Sep-05, Volume: 73, Issue:17

    Topics: Azides; Cyclic N-Oxides; Cyclization; Free Radical Scavengers; Mercury; Models, Chemical; Oligonucleotides; Stereoisomerism; Thymidine; Triazoles

2008
Nucleosides and oligonucleotides containing 1,2,3-triazole residues with nucleobase tethers: synthesis via the azide-alkyne 'click' reaction.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Alkynes; Azides; Combinatorial Chemistry Techniques; DNA; Fluorescent Dyes; Models, Chemical; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Organophosphorus Compounds; Triazoles

2008
Synthesis and polymerase chain reaction amplification of DNA strands containing an unnatural triazole linkage.
    Journal of the American Chemical Society, 2009, Mar-25, Volume: 131, Issue:11

    Topics: DNA; DNA-Directed DNA Polymerase; Oligonucleotides; Polymerase Chain Reaction; Thymidine; Triazoles

2009
Synthesis and base-pairing properties of C-nucleotides having 1-substituted 1H-1,2,3-triazoles.
    Bioorganic & medicinal chemistry letters, 2009, Jun-15, Volume: 19, Issue:12

    Topics: Base Pairing; Methods; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Nucleotides; Oligonucleotides; Transition Temperature; Triazoles

2009
Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:3

    Topics: Catalysis; Copper; Cyclization; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrimidines; Triazoles

2010
Pyrene-functionalized triazole-linked 2'-deoxyuridines-probes for discrimination of single nucleotide polymorphisms (SNPs).
    Chemical communications (Cambridge, England), 2010, Jul-21, Volume: 46, Issue:27

    Topics: Deoxyuridine; DNA Probes; Nucleic Acid Hybridization; Oligonucleotides; Polymorphism, Single Nucleotide; Pyrenes; Spectrometry, Fluorescence; Triazoles

2010
Synthesis and triplex-forming ability of oligonucleotides bearing 1-substituted 1H-1,2,3-triazole nucleobases.
    Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3

    Topics: Azides; Base Pairing; DNA; Drug Design; Heterocyclic Compounds; Oligonucleotides; Phenylurea Compounds; Triazoles

2011
Synthesis and hybridization data of oligonucleotide analogs with triazole internucleotide linkages, potential antiviral and antitumor agents.
    Bioorganic chemistry, 2011, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Antiviral Agents; DNA; Molecular Structure; Nucleic Acid Hybridization; Oligonucleotides; Organophosphorus Compounds; RNA; Triazoles

2011
Duplex and triplex formation of mixed pyrimidine oligonucleotides with stacking of phenyl-triazole moieties in the major groove.
    The Journal of organic chemistry, 2011, Aug-05, Volume: 76, Issue:15

    Topics: Base Sequence; Circular Dichroism; Deoxycytidine; Deoxyuridine; DNA, Complementary; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Nucleosides; Nucleotides; Oligonucleotides; Pyrimidines; RNA, Complementary; Triazoles

2011
C2'-pyrene-functionalized triazole-linked DNA: universal DNA/RNA hybridization probes.
    The Journal of organic chemistry, 2012, Jan-06, Volume: 77, Issue:1

    Topics: Base Pairing; DNA; DNA Probes; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Oligonucleotides; Pyrenes; RNA; RNA Probes; Spectrometry, Fluorescence; Triazoles

2012
Structure and dynamics of triazole-linked DNA: biocompatibility explained.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Dec-23, Volume: 17, Issue:52

    Topics: Base Pairing; Biocompatible Materials; Click Chemistry; DNA; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Triazoles

2011
Synthesis and hybridization properties of oligonucleotides modified with 5-(1-aryl-1,2,3-triazol-4-yl)-2'-deoxyuridines.
    Organic & biomolecular chemistry, 2012, Nov-21, Volume: 10, Issue:43

    Topics: Deoxyuridine; Molecular Structure; Oligonucleotides; Triazoles

2012
Triazolyl donor/acceptor chromophore decorated unnatural nucleosides and oligonucleotides with duplex stability comparable to that of a natural adenine/thymine pair.
    The Journal of organic chemistry, 2013, Jan-18, Volume: 78, Issue:2

    Topics: Adenine; Base Pairing; Click Chemistry; DNA; Fluorescence; Magnetic Resonance Spectroscopy; Nucleosides; Oligonucleotides; Thymine; Triazoles

2013
Synthesis of triazole-linked oligonucleotides with high affinity to DNA complements and an analysis of their compatibility with biosystems.
    The Journal of organic chemistry, 2013, Jun-21, Volume: 78, Issue:12

    Topics: Deoxyribonucleases; DNA; Hydrolysis; Molecular Mimicry; Molecular Probes; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Oligonucleotides; Polymerase Chain Reaction; Triazoles

2013
Triplex-forming ability of oligonucleotides containing 1-aryl-1,2,3-triazole nucleobases linked via a two atom-length spacer.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Base Pairing; Catalysis; Copper; Cycloaddition Reaction; DNA; Nucleosides; Oligonucleotides; Phase Transition; Transition Temperature; Triazoles; Ultraviolet Rays

2013
High-affinity RNA targeting by oligonucleotides displaying aromatic stacking and amino groups in the major groove. Comparison of triazoles and phenyl substituents.
    The Journal of organic chemistry, 2014, Apr-04, Volume: 79, Issue:7

    Topics: Amines; Deoxyuridine; DNA; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; RNA; Triazoles

2014
4'-C-[(4-trifluoromethyl-1H-1,2,3-triazol-1-yl)methyl]thymidine as a sensitive (19)F NMR sensor for the detection of oligonucleotide secondary structures.
    The Journal of organic chemistry, 2014, Apr-18, Volume: 79, Issue:8

    Topics: Base Sequence; DNA; HIV Long Terminal Repeat; HIV-1; Magnetic Resonance Spectroscopy; Oligonucleotides; Protein Structure, Secondary; RNA; Thymidine; Triazoles

2014
Triazole-linked analogues of DNA and RNA ((TL)DNA and (TL)RNA): synthesis and functions.
    Chemical record (New York, N.Y.), 2014, Volume: 14, Issue:1

    Topics: Click Chemistry; DNA; Nucleic Acid Conformation; Oligonucleotides; RNA; Solid-Phase Synthesis Techniques; Triazoles

2014
Concise Synthesis of Triazole-Linked 5'-Peptide-Oligonucleotide Conjugates by Click Chemistry.
    Nucleosides, nucleotides & nucleic acids, 2015, Volume: 34, Issue:8

    Topics: Chromatography, High Pressure Liquid; Click Chemistry; Hydrolysis; Oligonucleotides; Peptides; Triazoles

2015
Chimeric RNA Oligonucleotides with Triazole and Phosphate Linkages: Synthesis and RNA Interference.
    Chemistry, an Asian journal, 2015, Volume: 10, Issue:12

    Topics: Bacterial Proteins; Base Sequence; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Fluorescence; Oligonucleotides; Phosphates; RNA Interference; RNA, Small Interfering; Triazoles

2015
Increasing the Stability of DNA:RNA Duplexes by Introducing Stacking Phenyl-Substituted Pyrazole, Furan, and Triazole Moieties in the Major Groove.
    The Journal of organic chemistry, 2015, Oct-02, Volume: 80, Issue:19

    Topics: Circular Dichroism; Deoxyuridine; DNA; Furans; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Pyrazoles; RNA; Triazoles

2015
Chimeric RNA Oligonucleotides Incorporating Triazole-Linked Trinucleotides: Synthesis and Function as mRNA in Cell-Free Translation Reactions.
    The Journal of organic chemistry, 2016, 10-07, Volume: 81, Issue:19

    Topics: Carbon-13 Magnetic Resonance Spectroscopy; Cell-Free System; Chromatography, High Pressure Liquid; Oligonucleotides; Protein Biosynthesis; Proton Magnetic Resonance Spectroscopy; RNA, Messenger; Spectrometry, Mass, Electrospray Ionization; Triazoles

2016
Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation.
    Journal of the American Chemical Society, 2017, 02-01, Volume: 139, Issue:4

    Topics: DNA; DNA Replication; Electrons; Esters; Kinetics; Oligonucleotides; Polymerase Chain Reaction; Triazoles

2017
Synthesis and hybridization properties of oligonucleotide analogues with novel acyclic triazole internucleotide linkages.
    Bioorganic chemistry, 2017, Volume: 72

    Topics: DNA; Dose-Response Relationship, Drug; Molecular Structure; Oligonucleotides; Structure-Activity Relationship; Thermodynamics; Triazoles

2017
Synthesis and biological properties of triazole-linked locked nucleic acid.
    Chemical communications (Cambridge, England), 2017, Aug-03, Volume: 53, Issue:63

    Topics: Binding Sites; Molecular Conformation; Oligonucleotides; RNA, Small Interfering; Triazoles

2017
Towards Improved Oligonucleotide Therapeutics Through Faster Target Binding Kinetics.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Oct-12, Volume: 23, Issue:57

    Topics: Base Sequence; Cell Line; Circular Dichroism; Genetic Therapy; Humans; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; Polyamines; RNA; Spermine; Static Electricity; Surface Plasmon Resonance; Triazoles; Uracil

2017
Locked nucleic acid (LNA) enhances binding affinity of triazole-linked DNA towards RNA.
    Chemical communications (Cambridge, England), 2017, Aug-03, Volume: 53, Issue:63

    Topics: Binding Sites; DNA; Molecular Conformation; Oligonucleotides; RNA; Triazoles

2017
Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat.
    Nucleic acid therapeutics, 2018, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Cell Line; Child; Female; Fibroblasts; Frataxin; Friedreich Ataxia; Gene Expression Regulation; Genetic Therapy; Humans; Introns; Iron-Binding Proteins; Male; Oligonucleotides; Oligonucleotides, Antisense; Primary Cell Culture; RNA, Double-Stranded; RNA, Messenger; Triazoles; Trinucleotide Repeat Expansion

2018
Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions.
    Bioconjugate chemistry, 2018, 06-20, Volume: 29, Issue:6

    Topics: Acetylgalactosamine; Amides; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Esterification; HeLa Cells; Humans; Models, Molecular; Oligonucleotides; RNA, Small Interfering; Triazoles

2018
A flow platform for degradation-free CuAAC bioconjugation.
    Nature communications, 2018, 10-01, Volume: 9, Issue:1

    Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Molecular Structure; Oligonucleotides; Oxidation-Reduction; Peptides; Temperature; Triazoles; Water

2018
An artificial triazole backbone linkage provides a split-and-click strategy to bioactive chemically modified CRISPR sgRNA.
    Nature communications, 2019, 04-08, Volume: 10, Issue:1

    Topics: Catalysis; Cell Line, Tumor; Click Chemistry; Copper; CRISPR-Cas Systems; Cycloaddition Reaction; DNA; DNA Cleavage; Gene Editing; Humans; Oligonucleotides; RNA, Guide, Kinetoplastida; Triazoles

2019
Duplex-forming Oligonucleotide of Triazole-linked RNA.
    Chemistry, an Asian journal, 2019, Oct-01, Volume: 14, Issue:19

    Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Molecular Dynamics Simulation; Nucleic Acid Conformation; Oligonucleotides; RNA; Solid-Phase Synthesis Techniques; Triazoles

2019
Fluorescence immunoassay for multiplex detection of organophosphate pesticides in agro-products based on signal amplification of gold nanoparticles and oligonucleotides.
    Food chemistry, 2020, Oct-01, Volume: 326

    Topics: Chlorpyrifos; Fluorescence; Food Analysis; Gold; Immunoassay; Insecticides; Limit of Detection; Metal Nanoparticles; Oligonucleotides; Organothiophosphates; Parathion; Pesticides; Triazoles

2020
Ester modification at the 3' end of anti-microRNA oligonucleotides increases potency of microRNA inhibition.
    Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29

    Topics: Argonaute Proteins; Cell Line; Click Chemistry; Drug Evaluation, Preclinical; Esters; Exonucleases; Humans; MicroRNAs; Molecular Docking Simulation; Oligonucleotides; Oligonucleotides, Antisense; Phosphoric Diester Hydrolases; Protein Conformation; Small Molecule Libraries; Structure-Activity Relationship; Triazoles

2021