triazoles has been researched along with olaparib in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 5 (41.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dang, CV; Fan, L; Fan, Y; Hu, X; Hu, Z; Huang, Q; Li, C; Montone, K; Pi, J; Shan, W; Tang, Z; Tanyi, JL; Wang, Y; Yang, L; Yuan, J; Zhang, L; Zhang, Y | 1 |
| Bitler, BG; Fatkhutdinov, N; Karakashev, S; Khabele, D; Kossenkov, AV; Simpkins, F; Speicher, D; Wilson, AJ; Yokoyama, Y; Zhang, R; Zhao, B; Zhu, H | 1 |
| Barbina, M; Bolis, M; Caponnetto, F; Damante, G; Di Loreto, C; Garattini, E; Gerratana, L; Mio, C; Puglisi, F; Zanello, A | 1 |
| Bagnolini, G; Balboni, A; Cavalli, A; De Franco, F; Di Stefano, G; Falchi, F; Farabegoli, F; Giacomini, E; Girotto, S; Manerba, M; Milano, D; Minucci, S; Pallavicini, I; Pellicciari, R; Roberti, M; Robertson, J; Schipani, F | 1 |
| Bradner, JE; Council, LN; Fehling, SC; Gamblin, TL; Garcia, PL; Miller, AL; van Waardenburg, RCAM; Yang, ES; Yoon, KJ | 1 |
| Fehling, SC; Garcia, PL; Miller, AL; Vance, RB; Yoon, KJ | 1 |
| Beattie, D; Cadogan, EB; Cairns, J; Davies, BR; Dean, E; Farrington, PM; Fawell, SE; Finlay, MRV; Fok, JHL; Follia, V; Goldberg, FW; Hollingsworth, SJ; James, N; Karmokar, A; Lamont, GM; Ling, S; Nikkilä, J; O'Connor, LO; O'Connor, MJ; Ramos-Montoya, A; Smith, A; Vazquez-Chantada, M; Wijnhoven, PWG; Willis, SE; Wilson, J | 1 |
| Fan, P; Fang, R; Jin, X; Liu, T; Lu, X; Zeng, L; Zhang, B | 1 |
| Abeykoon, JP; Boughey, JC; Boysen, J; Carr, RM; Couch, FJ; Dasari, S; Feldman, AL; Goetz, MP; Hou, X; Hu, C; Kapoor, P; King, RL; Kumar, S; Manske, MK; Mladek, AC; Molina, JR; Nowakowski, KE; Paludo, J; Parikh, SA; Patnaik, MM; Phillips, JL; Ravindran, A; Robinson, SI; Sarkaria, JN; Stenson, MJ; Wang, L; Weroha, SJ; Witzig, TE; Wu, X; Yu, J | 1 |
| Amero, P; Bayraktar, E; Coleman, RL; Dasari, SK; Glassman, D; Handley, KF; Ivan, C; Joseph, R; Kim, M; Landesman, Y; Ma, S; Nguyen, N; Powell, RT; Ram, PT; Rodriguez-Aguayo, C; Sobieski, M; Sood, AK; Stephan, C; Stur, E; Umamaheswaran, S; Wen, Y; Westin, SN | 1 |
| Chen, C; Chen, W; Chen, X; Dan, S; Hu, J; Kang, B; Wang, YJ; Zhang, X | 1 |
| Anastasia, A; Baakza, H; Bani, MR; Cadogan, EB; Chiorino, G; Dellavedova, G; Ghilardi, C; Giavazzi, R; James, N; Ramos-Montoya, A; Russo, M; Wilson, J | 1 |
12 other study(ies) available for triazoles and olaparib
| Article | Year |
|---|---|
Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition.
Topics: Acetanilides; Animals; Antineoplastic Agents; Azepines; Benzodiazepines; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Drug Synergism; Female; Heterocyclic Compounds, 3-Ring; Homologous Recombination; Humans; Ovarian Neoplasms; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Triazoles | 2017 |
BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer.
Topics: Animals; Azepines; BRCA1 Protein; BRCA2 Protein; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; Drug Synergism; Epithelial Cells; Female; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Nuclear Proteins; Ovarian Neoplasms; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein-Tyrosine Kinases; Proteins; Triazoles | 2017 |
BET proteins regulate homologous recombination-mediated DNA repair: BRCAness and implications for cancer therapy.
Topics: Antineoplastic Agents; Azepines; Benzodiazepines; BRCA1 Protein; Cell Cycle Proteins; Cell Line, Tumor; Cisplatin; DNA Damage; Female; Gene Expression Regulation, Neoplastic; Humans; Nuclear Proteins; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Rad51 Recombinase; Recombinational DNA Repair; RNA Interference; Transcription Factors; Triazoles; Triple Negative Breast Neoplasms | 2019 |
Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells.
Topics: Antineoplastic Agents; BRCA2 Protein; Cell Line, Tumor; Drug Synergism; Homologous Recombination; Humans; Molecular Mimicry; Mutation; Pancreatic Neoplasms; Phthalazines; Piperazines; Protein Binding; Rad51 Recombinase; Triazoles | 2019 |
The BET inhibitor JQ1 attenuates double-strand break repair and sensitizes models of pancreatic ductal adenocarcinoma to PARP inhibitors.
Topics: Acid Anhydride Hydrolases; Animals; Azepines; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Models, Animal; DNA Breaks, Double-Stranded; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Histones; Humans; Ku Autoantigen; Mice; Pancreatic Neoplasms; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Triazoles; Xenograft Model Antitumor Assays | 2019 |
The combination of BET and PARP inhibitors is synergistic in models of cholangiocarcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Bile Duct Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cholangiocarcinoma; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; RNA, Small Interfering; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays | 2020 |
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.
Topics: A549 Cells; Animals; Antibiotics, Antineoplastic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; DNA-Activated Protein Kinase; Doxorubicin; Drug Synergism; Genomic Instability; Humans; Lung Neoplasms; Mice; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Glycols; Protein Kinase Inhibitors; Purines; Pyrans; Radiation Tolerance; Radiotherapy; Triazoles; Xenograft Model Antitumor Assays | 2019 |
PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Azepines; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cytoprotection; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Phthalazines; Piperazines; Prognosis; Proteins; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins; Transfection; Triazoles | 2019 |
Salicylates enhance CRM1 inhibitor antitumor activity by induction of S-phase arrest and impairment of DNA-damage repair.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle Checkpoints; Choline; DNA Repair; DNA Replication; DNA, Neoplasm; Drug Combinations; Drug Synergism; Exportin 1 Protein; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Karyopherins; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Proteins; Phthalazines; Piperazines; Random Allocation; Receptors, Cytoplasmic and Nuclear; S Phase Cell Cycle Checkpoints; Salicylates; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disease Models, Animal; Female; High-Throughput Screening Assays; Humans; Hydrazines; Mice; Mice, Nude; Ovarian Neoplasms; Phthalazines; Piperazines; Triazoles | 2021 |
DNA repair proteins cooperate with SOX2 in regulating the transition of human embryonic stem cells to neural progenitor cells.
Topics: Animals; Cell Differentiation; Cell Line; Computational Biology; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Human Embryonic Stem Cells; Humans; Neural Stem Cells; Phthalazines; Piperazines; Purines; Pyrans; Signal Transduction; SOXB1 Transcription Factors; Triazoles | 2022 |
The DNA-PK Inhibitor AZD7648 Sensitizes Patient-Derived Ovarian Cancer Xenografts to Pegylated Liposomal Doxorubicin and Olaparib Preventing Abdominal Metastases.
Topics: Animals; Cell Line, Tumor; DNA; Doxorubicin; Female; Heterografts; Humans; Mice; Ovarian Neoplasms; Phthalazines; Piperazines; Polyethylene Glycols; Protein Kinase Inhibitors; Purines; Pyrans; Triazoles | 2022 |