triazoles has been researched along with nadp in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (34.78) | 18.7374 |
| 1990's | 10 (21.74) | 18.2507 |
| 2000's | 12 (26.09) | 29.6817 |
| 2010's | 6 (13.04) | 24.3611 |
| 2020's | 2 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Chance, B; Oshino, N | 1 |
| Decker, CJ; Doerge, DR | 1 |
| Davenport, JD; Hirsch, KS; Holden, HE; Jones, CD; Krumkalns, EV; Stamm, N; Suhr, RG; Taylor, HM; Winter, MA | 1 |
| Heller, W; Koch, U; Kühnl, T; Wellmann, E | 1 |
| Bend, JR; Mathews, JM | 1 |
| Bend, JR; Dostal, LA; Mathews, JM | 1 |
| Ariga, K; Nakamura, Y; Nakaya, K; Obata, F | 1 |
| Ariga, K; Maruyama, I; Nakamura, Y; Nakaya, K; Obata, F | 1 |
| Baron, J; Tephly, TR | 2 |
| Creaven, PJ; Reese, WN; Roach, MK | 1 |
| Ichikawa, Y; Yamano, T | 1 |
| Basford, RE; Gee, JB; Thomas, C; Vassallo, CL; Vogt, MT | 1 |
| Carter, EA; Isselbacher, KJ | 2 |
| Kalant, H; Khanna, JM; Lin, G | 1 |
| Hokama, Y; Yanagihara, E | 1 |
| Reddy, J; Svoboda, D | 1 |
| Colby, HD; Kominami, S; Mico, BA; Takemori, S; Voigt, JM; Xu, D | 1 |
| Bend, JR; Knickle, LC | 1 |
| Amore, BM; Bennett, GD; Finnell, RH; Kalhorn, TF; Lillibridge, JH; Nelson, SD; Slattery, JT | 1 |
| Bend, JR; Sinal, CJ | 1 |
| Ring, SC; Shao, R; Tarloff, JB | 1 |
| Granger, DN; Horie, Y; Russell, J; Shanley, TP; Wolf, R | 1 |
| Lin, EH; Marks, GS; Wong, SG | 1 |
| Schepetkin, IA | 1 |
| Blanchard, AP; Broudy, MI; Cargill, CE; Crespi, CL; Dandeneau, AA; Dehal, SS; Erve, JC; Goodwin, JJ; Ho, T; Patten, CJ; Sharma, R; Stresser, DM; Turner, SD | 1 |
| Ballou, DP; Hollenberg, PF; Kent, UM; Pascual, L; Roof, RA | 1 |
| Ayhan-Kilcigil, G; Can Eke, B; Işcan, M; Kuş, C | 1 |
| Chiu, PY; Ko, KM; Mak, DH; Poon, MK | 1 |
| Bellward, GD; Chang, TK; Levine, M; Madeira, M; Mirfazaelian, A | 1 |
| Hutzler, JM; Locuson, CW; Tracy, TS | 1 |
| Bergeron, L; Blat, Y; Flynn, MJ; Gates, C; Golla, R; Gordon, DA; Hamann, LG; Li, JJ; Ma, Z; Nayeem, A; Pedicord, DL; Sahni-Arya, B; Salyan, ME; Seethala, R; Wang, H; Wu, SC | 1 |
| Clarke, SE; Hollis, FJ; Maggs, JL; Naisbitt, DJ; Park, BK; Sanderson, JP | 1 |
| Degraffenreid, M; He, X; Jaen, JC; Labelle, M; Liu, J; Meininger, D; Powers, JP; Shan, B; Sudom, A; Sun, D; Tu, H; Ursu, S; Walker, NP; Wang, Z; Xu, H; Yamamoto, H; Yan, X | 1 |
| Desta, Z; Flockhart, DA; Jeong, S; Woo, MM | 1 |
| Brown, C; Goldsmith, MR; Kenneke, JF; Mazur, CS | 1 |
| Akyüz, M; Ata, S | 1 |
| Bauman, JN; Chen, Y; Eng, H; Kalgutkar, AS; McDonald, TS; Niosi, M; Simila, ST; Warmus, J; Wolford, A | 1 |
| Kelly, DE; Kelly, SL; Parker, JE; Warrilow, AG | 1 |
| Du, F; Li, X; Liu, Z; Xing, J | 1 |
| Brunco, A; Massarotti, A; Sorba, G; Tron, GC | 1 |
| Allanki, AD; Balabadra, S; Kotni, M; Manga, V; Prasad, R; Sijwali, PS | 1 |
| Baj, F; Baravalle, R; Ciaramella, A; Di Nardo, G; Gilardi, G | 1 |
| Chen, C; Ge, M; Liao, H; Liu, D; Pan, L; Shen, N; Wu, S; Yao, W | 1 |
| Bottino, C; Caretti, G; Filippakopoulos, P; Fittipaldi, R; Mamchaoui, K; Nevi, L; Segatto, M; Szokoll, R | 1 |
46 other study(ies) available for triazoles and nadp
| Article | Year |
|---|---|
Properties of glutathione release observed during reduction of organic hydroperoxide, demethylation of aminopyrine and oxidation of some substances in perfused rat liver, and their implications for the physiological function of catalase.
Topics: Aminopyrine; Animals; Benzylamines; Catalase; Cell Separation; Glutathione; Glutathione Peroxidase; Glycolates; Liver; Male; Mitochondria, Liver; NADP; Nucleotides; Oxidation-Reduction; Perfusion; Peroxides; Phenobarbital; Rats; Triazoles; Uric Acid | 1977 |
Covalent binding of 14C- and 35S-labeled thiocarbamides in rat hepatic microsomes.
Topics: Animals; Antithyroid Agents; Benzimidazoles; Biotransformation; Carbon Radioisotopes; Dexamethasone; Glutathione; Male; Methimazole; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Sulfhydryl Compounds; Sulfur Radioisotopes; Triazoles | 1992 |
Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups.
Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Chemical Phenomena; Chemistry; Female; Gonadotropins, Equine; Imidazoles; Microsomes; Molecular Structure; NADP; Ovary; Pyrazoles; Pyridines; Pyrimidines; Rats; Structure-Activity Relationship; Thiazoles; Triazoles; X-Ray Diffraction | 1990 |
Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures.
Topics: Carbon Monoxide; Cells, Cultured; Chlorogenic Acid; Cytochrome c Group; Light; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Plants; Stereoisomerism; Substrate Specificity; Triazoles; Vegetables | 1987 |
N-alkylaminobenzotriazoles as isozyme-selective suicide inhibitors of rabbit pulmonary microsomal cytochrome P-450.
Topics: Alkylation; Animals; Benzphetamine; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lung; Male; Microsomes; NADP; Oxazines; Oxygenases; Rabbits; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Isoenzymes; Lung; Male; Microsomes; NADP; Oxidoreductases; Oxidoreductases, N-Demethylating; Oxygenases; Perfusion; Rabbits; Stereoisomerism; Triazoles | 1985 |
Reaction of chloroplasts with diazonium-1, 2, 4-triazole.
Topics: Amino Acids; Centrifugation; Chlorophyll; Chloroplasts; Densitometry; Diazonium Compounds; NADP; Plant Proteins; Polyethylene Glycols; Triazoles | 1974 |
Photochemical activities of chloroplasts treated with diazonium-1,2,4-triazole.
Topics: Chloroplasts; Chromatography, DEAE-Cellulose; Diazonium Compounds; Ferredoxins; Indophenol; Methylurea Compounds; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Phenazines; Phosphorus Radioisotopes; Photophosphorylation; Plants; Triazoles | 1974 |
The role of heme synthesis during the induction of hepatic microsomal cytochrome P-450 and drug metabolism produced by benzpyrene.
Topics: Acyltransferases; Amino Acids; Animals; Azo Compounds; Benzopyrenes; Carbon Isotopes; Cytochromes; Depression, Chemical; Enzyme Induction; Glycine; Heme; Levulinic Acids; Liver; Male; Microsomes; NADP; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical; Time Factors; Transferases; Triazoles | 1969 |
Ethanol oxidation in the microsomal fraction of rat liver.
Topics: Acetaldehyde; Animals; Azides; Biphenyl Compounds; Carbon Monoxide; Catalase; Cattle; Cyanides; Cytochromes; Depression, Chemical; Ethanol; Glucose; Glucose Oxidase; Liver; Male; Microsomes; NADP; Peroxides; Proadifen; Rats; Stimulation, Chemical; Triazoles | 1969 |
Preparation and physicochemical properties of functional hemoprotein P450 from mammalian tissue microsomes.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Chemical Phenomena; Chemistry; Cytochromes; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Imidazoles; Male; Methods; Microsomes; Microsomes, Liver; Models, Chemical; NADP; Nitroso Compounds; Osmolar Concentration; Oxidation-Reduction; Pigments, Biological; Protein Denaturation; Rabbits; Solubility; Spectrophotometry; Swine; Temperature; Triazoles; Trypsin; Ultraviolet Rays | 1970 |
Effect of 3-amino-1,2,4-triazole on the stimulation of hepatic microsomal heme synthesis and induction of hepatic microsomal oxidases produced by phenobarbital.
Topics: Animals; Azo Compounds; Carbon Isotopes; Cytochromes; Enzyme Induction; Heme; Hydro-Lyases; Iron Isotopes; Levulinic Acids; Male; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Phenobarbital; Rats; Time Factors; Triazoles | 1969 |
Peroxidative metabolism in alveolar macrophages.
Topics: Alcohols; Animals; Carbon Dioxide; Carbon Isotopes; Catalase; D-Amino-Acid Oxidase; Glucose; Glutathione; Hydrogen Peroxide; Macrophages; NADP; Oxygen Consumption; Phagocytosis; Pulmonary Alveoli; Rabbits; Triazoles | 1971 |
The role of microsomes in the hepatic metabolism of ethanol.
Topics: Acetates; Adenine Nucleotides; Aerobiosis; Amino Alcohols; Anaerobiosis; Animals; Azides; Bile Acids and Salts; Carbon Monoxide; Catalase; Cell Fractionation; Chlorides; Chloromercuribenzoates; Copper; Cyanides; Diet; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Female; Hot Temperature; Hydrogen Peroxide; Iron; Liver; Mercury; Microsomes, Liver; NAD; NADP; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Sulfides; Triazoles | 1971 |
Metabolism of ethanol by rat liver microsomal enzymes.
Topics: Amines; Animals; Azides; Barium; Bile Acids and Salts; Cyanides; Digitalis Glycosides; Ethanol; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Male; Metabolism; Microsomes, Liver; NADP; Oxides; Potassium; Proadifen; Pyrazoles; Rats; Saponins; Sodium; Spirostans; Triazoles; Ultracentrifugation | 1970 |
The reversible inhibition of catalase activity by nucleotides and its possible relationship to mouse liver catalase depression induced by biological substances.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Allyl Compounds; Animals; Blood Group Antigens; Bradykinin; C-Reactive Protein; Carcinoma, Ehrlich Tumor; Catalase; Depression, Chemical; Endotoxins; Escherichia coli; Glycoproteins; Humans; In Vitro Techniques; Kidney; Leukocytes; Lipopolysaccharides; Liver; Mice; NAD; NADP; Peroxidases; Salmonella typhimurium; Talc; Tissue Extracts; Triazoles | 1971 |
Microbodies (peroxisomes) in the interstitial cells of rodent testes.
Topics: Acid Phosphatase; Aldehydes; Amines; Androgens; Animals; Azides; Biphenyl Compounds; Cholesterol; Clofibrate; Cyanides; Guinea Pigs; Histocytochemistry; Hydrogen-Ion Concentration; Inclusion Bodies; Leydig Cells; Male; Mice; Microscopy, Electron; NADP; Osmium; Peroxidases; Pyruvates; Rats; Rats, Inbred Strains; Triazoles | 1972 |
Hepatic microsomal ethanol oxidation. Mechanism and physiologic significance.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Carbon Tetrachloride; Catalase; Culture Techniques; Cyanides; Diet; Ethanol; Female; Hydrogen Peroxide; Microsomes, Liver; NADP; Rats; Triazoles | 1972 |
Inhibition of adrenal cytochromes P450 by 1-aminobenzotriazole in vitro. Selectivity for xenobiotic metabolism.
Topics: Adrenal Glands; Animals; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guinea Pigs; Male; Microsomes; NADP; Steroid 11-beta-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases; Triazoles; Xenobiotics | 1994 |
Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Guinea Pigs; Lung; Male; Metyrapone; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Triazoles | 1994 |
Protein-reactive metabolites of carbamazepine in mouse liver microsomes.
Topics: Animals; Anticonvulsants; Ascorbic Acid; Caffeic Acids; Carbamazepine; Carbon Monoxide; Catechol O-Methyltransferase; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxolanes; Enzyme Inhibitors; Epoxide Hydrolases; Female; Glutathione Transferase; Mice; Mice, Inbred Strains; Microsomes, Liver; NAD(P)H Dehydrogenase (Quinone); NADP; Piperonyl Butoxide; Sulfhydryl Compounds; Triazoles | 1996 |
Kinetics and selectivity of mechanism-based inhibition of guinea pig hepatic and pulmonary cytochrome P450 by N-benzyl-1-aminobenzotriazole and N-alpha-methylbenzyl-1-aminobenzotriazole.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guinea Pigs; In Vitro Techniques; Isoenzymes; Kinetics; Liver; Lung; Male; NADP; Oxazines; Triazoles | 1996 |
Coincubation of rat renal proximal tubules with hepatic subcellular fractions potentiates the effects of para-aminophenol.
Topics: Adenine Nucleotides; Aminophenols; Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Female; Glutathione; In Vitro Techniques; Kidney Tubules, Proximal; Liver; Mitochondria, Liver; NADP; Oxidation-Reduction; Oxygen Consumption; Pancreatitis-Associated Proteins; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Triazoles | 1997 |
Role of Kupffer cells in gut ischemia/reperfusion-induced hepatic microvascular dysfunction in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Endothelium, Vascular; Fibrinolytic Agents; Gadolinium; Intestinal Mucosa; Intestines; Kupffer Cells; Leukocytes; Liver Circulation; Mice; Mice, Inbred C57BL; NADP; Oxidative Stress; P-Selectin; Platelet Aggregation Inhibitors; Reperfusion Injury; Triazoles; Tumor Necrosis Factor-alpha | 1997 |
Cytochrome CYP sources of N-alkylprotoporphyrin IX after administration of porphyrinogenic xenobiotics to rats.
Topics: Allylisopropylacetamide; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Glucocorticoids; Male; Microsomes, Liver; NADP; Porphyrins; Protoporphyrins; Rats; Rats, Sprague-Dawley; Sydnones; Triazoles; Xenobiotics | 1999 |
Lucigenin luminescence elicited by microsomes and its modulation by nitroazole compounds.
Topics: Acridines; Animals; Cattle; Horses; Luminescent Measurements; Male; Metronidazole; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Superoxide Dismutase; Triazoles; Xanthine Oxidase | 1999 |
Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible.
Topics: Anti-Infective Agents; Bridged-Ring Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluorometry; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; NADP; Pleurotus; Solubility; Steroid Hydroxylases; Substrate Specificity; Triazoles; Xenobiotics | 2004 |
Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine.
Topics: Anaerobiosis; Animals; Benzphetamine; Coumarins; Cytochrome P-450 CYP2B1; Enzyme Inhibitors; Escherichia coli; Hydrogen Peroxide; Hydroxylation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Protein Binding; Rats; Rats, Long-Evans; Testosterone; Triazoles | 2004 |
Synthesis and antioxidant properties of some novel benzimidazole derivatives on lipid peroxidation in the rat liver.
Topics: Animals; Antioxidants; Benzimidazoles; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; Indicators and Reagents; Lipid Peroxidation; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; NADP; Rats; Semicarbazides; Spectrophotometry, Infrared; Thiadiazoles; Triazoles | 2004 |
Role of cytochrome P-450 in schisandrin B-induced antioxidant and heat shock responses in mouse liver.
Topics: Administration, Oral; Animals; Antioxidants; Cyclooctanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heat-Shock Response; Lignans; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mitochondria, Liver; NADP; Oxidative Stress; Polycyclic Compounds; Schisandraceae; Triazoles | 2005 |
The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.
Topics: Catalase; Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Humans; Kinetics; Microsomes, Liver; NADP; Oxidoreductases, O-Demethylating; Quinidine; Recombinant Proteins; Superoxide Dismutase; Triazoles | 2004 |
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.
Topics: Aniline Compounds; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Heme; Humans; Imidazoles; Itraconazole; Kinetics; Ligands; Light; Models, Chemical; Molecular Structure; NADP; Nonlinear Dynamics; Protein Binding; Pyrimidines; Recombinant Proteins; Reference Standards; Regression Analysis; Spectrum Analysis; Sulfaphenazole; Triazoles | 2007 |
Cofactor-specific modulation of 11beta-hydroxysteroid dehydrogenase 1 inhibitor potency.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Humans; Kinetics; NADP; Pyridines; Sulfonamides; Triazoles | 2007 |
Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.
Topics: Ascorbic Acid; Chromatography, High Pressure Liquid; Deferoxamine; Edetic Acid; Enzyme Inhibitors; Ferrous Compounds; Humans; Hydrogen Peroxide; Hydroxylation; Kinetics; Microsomes, Liver; Molecular Structure; NADP; Sulfamethoxazole; Tandem Mass Spectrometry; Triazoles | 2008 |
Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amino Acid Sequence; Binding Sites; Biological Assay; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Kinetics; Metabolic Diseases; Molecular Sequence Data; NADP; Structure-Activity Relationship; Sulfonamides; Triazoles | 2008 |
Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitro.
Topics: Antineoplastic Agents; Area Under Curve; Aromatase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Humans; Kinetics; Letrozole; Microsomes, Liver; NADP; Nitriles; Triazoles | 2009 |
Contrasting influence of NADPH and a NADPH-regenerating system on the metabolism of carbonyl-containing compounds in hepatic microsomes.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Chromatography, High Pressure Liquid; Cortisone; In Vitro Techniques; Indicators and Reagents; Kinetics; Male; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley; Triazoles; Xenobiotics | 2009 |
Determination of low level nitrite and nitrate in biological, food and environmental samples by gas chromatography-mass spectrometry and liquid chromatography with fluorescence detection.
Topics: 2-Naphthylamine; Chromatography, Gas; Chromatography, Liquid; Environment; Food Analysis; Gastric Juice; Humans; Hydrogen-Ion Concentration; Mass Spectrometry; NADP; Nitrate Reductase; Nitrates; Nitrites; Reproducibility of Results; Sodium Hydroxide; Sonication; Spectrometry, Fluorescence; Triazoles; Water; Water Pollutants, Chemical | 2009 |
Utility of the carboxylesterase inhibitor bis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor.
Topics: Animals; Carboxylesterase; Dogs; Drug Stability; Female; Humans; Hydrolysis; Isoquinolines; Male; Mice; Microsomes, Liver; NADP; Nitrophenols; Organophosphorus Compounds; Oxidation-Reduction; Quinolines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Triazoles | 2010 |
Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens.
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Escherichia coli; Fluconazole; Fungal Proteins; Humans; Itraconazole; Ketoconazole; Kinetics; Lanosterol; NADP; Protein Binding; Pyrimidines; Recombinant Proteins; Species Specificity; Sterol 14-Demethylase; Triazoles; Voriconazole | 2013 |
Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Cysteine; Cytochrome P-450 Enzyme System; Dipeptides; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Glutathione; Humans; Inactivation, Metabolic; Male; Metabolic Networks and Pathways; Mice; Microsomes, Liver; NADP; Phenanthrenes; Plants, Medicinal; Triazoles; Tripterygium | 2014 |
ZINClick: a database of 16 million novel, patentable, and readily synthesizable 1,4-disubstituted triazoles.
Topics: Alkynes; Azides; Click Chemistry; Databases, Pharmaceutical; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Models, Molecular; Molecular Conformation; NADP; Patents as Topic; Protein Kinase Inhibitors; Small Molecule Libraries; Triazoles | 2014 |
Synthesis and evaluation of naphthyl bearing 1,2,3-triazole analogs as antiplasmodial agents, cytotoxicity and docking studies.
Topics: Antiprotozoal Agents; Crystallography, X-Ray; Enzyme Assays; Folic Acid Antagonists; HEK293 Cells; Humans; Molecular Docking Simulation; NADP; Naphthalenes; Plasmodium falciparum; Pyrimethamine; Triazoles | 2017 |
Identification of endocrine disrupting chemicals acting on human aromatase.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Biological Assay; Endocrine Disruptors; Enzyme-Linked Immunosorbent Assay; Estrone; Gene Expression; Humans; Ketoconazole; Ligands; NADP; Nicotine; Nitriles; Phenols; Protein Binding; Recombinant Proteins; Resveratrol; Sildenafil Citrate; Small Molecule Libraries; Stilbenes; Triazoles | 2018 |
High-fat diet increased NADPH-oxidase-related oxidative stress and aggravated LPS-induced intestine injury.
Topics: Adsorption; Animals; Benzoxazoles; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Acid-Binding Proteins; Humans; Intestines; Lipopolysaccharides; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidases; Obesity; Oxidation-Reduction; Oxidative Stress; Permeability; Reactive Oxygen Species; Tight Junction Proteins; Tight Junctions; Triazoles | 2020 |
BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy.
Topics: Animals; Azepines; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NADP; NADPH Oxidases; Neuromuscular Diseases; Nuclear Proteins; Oxidative Stress; Reactive Oxygen Species; Transcription Factors; Triazoles | 2020 |