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triazoles and n-benzyl-1-aminobenzotriazole

triazoles has been researched along with n-benzyl-1-aminobenzotriazole in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (75.00)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bend, JR; Woodcroft, KJ1
Bend, JR; Grimm, SW; Halpert, JR1
Bend, JR; Knickle, LC; Philpot, RM1
Bend, JR; House, AA; Knickle, LC; Webb, CD1
Bend, JR; Falkner, KC; Horton, JE; McCallum, GP1
Bend, JR; Sinal, CJ1
Bend, JR; Webb, CD; Weedon, AC; Woodcroft, KJ; Yao, M1
Bend, JR; Chamberlin, BA; Gage, DA; Hollenberg, PF; Kent, UM1
Bend, JR; Halpert, JR; Hanna, IH; Hollenberg, PF; Kent, UM; Szklarz, GD; Vaz, AD1
Bend, JR; Moorthy, B; Parker, KM; Smith, CV; Welty, SE1
Ballou, DP; Hollenberg, PF; Kent, UM; Pascual, L; Roof, RA1
Jian, FF; Jiao, K; Sun, W; Wang, QX1

Other Studies

12 other study(ies) available for triazoles and n-benzyl-1-aminobenzotriazole

ArticleYear
N-aralkylated derivatives of 1-aminobenzotriazole as isozyme-selective, mechanism-based inhibitors of guinea pig hepatic cytochrome P-450 dependent monooxygenase activity.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:9

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Isoenzymes; Kinetics; Liver; Male; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Triazoles

1990
Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Activation; Humans; Isoenzymes; Kidney; Kinetics; Liver; Mice; Microsomes, Liver; Phenobarbital; Rabbits; Recombinant Proteins; Steroid Hydroxylases; Triazoles

1995
N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Guinea Pigs; Isoenzymes; Liver; Lung; Male; Phenobarbital; Sensitivity and Specificity; Triazoles

1994
Mechanism-based inactivation of cytochrome P450 1A1 by N-aralkyl-1-aminobenzotriazoles in guinea pig kidney in vivo and in vitro: minimal effects on metabolism of arachidonic acid by renal P450-dependent monooxygenases.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Guinea Pigs; Kidney; Male; Microsomes; Microsomes, Liver; Oxidoreductases; Oxygenases; Triazoles

1993
Microsomal cytochrome P450 1A1 dependent monooxygenase activity in guinea pig heart: induction, inhibition, and increased activity by addition of exogenous NADPH-cytochrome P450 reductase.
    Canadian journal of physiology and pharmacology, 1993, Volume: 71, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Male; Microsomes; Myocardium; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Oxygenases; Triazoles

1993
Kinetics and selectivity of mechanism-based inhibition of guinea pig hepatic and pulmonary cytochrome P450 by N-benzyl-1-aminobenzotriazole and N-alpha-methylbenzyl-1-aminobenzotriazole.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:9

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guinea Pigs; In Vitro Techniques; Isoenzymes; Kinetics; Liver; Lung; Male; NADP; Oxazines; Triazoles

1996
Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Chemical research in toxicology, 1997, Volume: 10, Issue:5

    Topics: Animals; Biotransformation; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Lung; Male; Microsomes; Microsomes, Liver; Protein Binding; Triazoles

1997
Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.
    Chemical research in toxicology, 1997, Volume: 10, Issue:5

    Topics: Animals; Apoproteins; Coumarins; Cytochrome P-450 CYP2B1; Iodobenzenes; Kinetics; Liver; Male; Protein Binding; Rats; Rats, Inbred Strains; Substrate Specificity; Triazoles

1997
Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.
    Biochemistry, 1997, Sep-30, Volume: 36, Issue:39

    Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B1; Glycine; Heme; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Rats; Rats, Inbred F344; Rats, Wistar; Triazoles

1997
Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: Animals; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Enzyme Inhibitors; Hyperoxia; Liver; Male; Microsomes; Oxazines; Oxygen; Pleural Effusion; Protein Isoforms; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Time Factors; Triazoles

2000
Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine.
    Archives of biochemistry and biophysics, 2004, Mar-15, Volume: 423, Issue:2

    Topics: Anaerobiosis; Animals; Benzphetamine; Coumarins; Cytochrome P-450 CYP2B1; Enzyme Inhibitors; Escherichia coli; Hydrogen Peroxide; Hydroxylation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Protein Binding; Rats; Rats, Long-Evans; Testosterone; Triazoles

2004
Synthesis, characterization and DNA-binding properties of a new cobalt(II) complex: Co(bbt)2Cl2.
    Journal of inorganic biochemistry, 2005, Volume: 99, Issue:6

    Topics: Animals; Cobalt; Crystallography, X-Ray; DNA; Electrochemistry; In Vitro Techniques; Male; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Triazoles

2005