triazoles has been researched along with midazolam in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 10 (43.48) | 24.3611 |
| 2020's | 4 (17.39) | 2.80 |
| Authors | Studies |
|---|---|
| Holtzman, SG; Mumford, GK | 1 |
| al-Dubai, Z; Beraus, W; Conca, A; König, P | 1 |
| Alfaro, CL; Ereshefsky, L; Lam, YW; Miller, M | 1 |
| France, CP; McMahon, LR | 1 |
| Laine, K; Leino, K; Neuvonen, PJ; Olkkola, KT; Saari, TI; Valtonen, M | 1 |
| Mathiasen, LS; Mirza, NR; Rodgers, RJ | 1 |
| Abel, S; Muirhead, GJ; Ridgway, CE; Russell, D; Whitlock, LA | 1 |
| Krishna, G; Ma, L; Martinho, M; McLeod, J; Moton, A; Savant, I; Seiberling, M | 1 |
| Clifton, PG; Dixon, CI; Morris, HV; Nilsson, S; Stephens, DN | 1 |
| Maren, K; Rojkjaer, L; Skerjanec, A; Wang, J | 1 |
| Burhenne, J; Haefeli, WE; Katzenmaier, S; Markert, C; Mikus, G; Riedel, KD | 1 |
| Bi, YA; El-Kattan, AF; Fenner, KS; Iseki, K; Kimoto, E; Lai, Y; Linder, C; Walsky, R; Whalen, KM; Xiao, Y; Yang, YS; Zhang, H | 1 |
| Isoherranen, N; Kunze, KL; Liu, JO; Lutz, JD; Nelson, WL; Peng, CC; Shi, W | 1 |
| Krishna, G; Ma, L; Martinho, M; Moton, A; O'Mara, E; Prasad, P | 1 |
| Frechen, S; Fuhr, U; Junge, L; Neuvonen, PJ; Olkkola, KT; Rokitta, D; Saari, TI; Suleiman, AA | 1 |
| Ancona, JK; Anderson, MS; Butterton, JR; Cilissen, C; De Lepeleire, I; Dockendorf, MF; Gilmartin, J; Guo, Y; Liu, R; Tetteh, E; Van Bortel, L; Wagner, JA | 1 |
| Chen, J; Ho, Q; Jaochico, A; Ly, J; Mao, J; Mukadam, S; Parrish, KE; Wright, M | 1 |
| Desrivot, J; Harrison, P; Namour, F; Tasset, C; Van der Aa, A; van't Klooster, G | 1 |
| Bogman, K; Bordogna, W; Cleary, Y; Dall, G; De Petris, L; Guerini, E; Martin-Facklam, M; Morcos, PN; Phipps, A; Viteri, S; Yu, L | 1 |
| Iba, Y; Kimura, T; Murai, H; Suzuki, H; Tanji, H | 1 |
| Chan, LN; Chen, KF; Lin, YS | 1 |
| Carreño, FO; Cohen-Wolkowiez, M; Edginton, AN; Gonzalez, D; Salerno, SN | 1 |
| Fukuhara, T; Kubota, R; Kuwata, A; Matsuo, Y; Matsuzaki, T; Shimizu, R; Sonoyama, T | 1 |
12 trial(s) available for triazoles and midazolam
| Article | Year |
|---|---|
Pharmacokinetic and pharmacodynamic interactions of oral midazolam with ketoconazole, fluoxetine, fluvoxamine, and nefazodone.
Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluoxetine; Fluvoxamine; Humans; Ketoconazole; Male; Midazolam; Piperazines; Triazoles | 2003 |
Effect of voriconazole on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.
Topics: Administration, Oral; Adult; Anesthetics, Intravenous; Antifungal Agents; Area Under Curve; Cross-Over Studies; Humans; Infusions, Intravenous; Male; Midazolam; Pyrimidines; Triazoles; Voriconazole | 2006 |
Effect of maraviroc on the pharmacokinetics of midazolam, lamivudine/zidovudine, and ethinyloestradiol/levonorgestrel in healthy volunteers.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anti-HIV Agents; CCR5 Receptor Antagonists; Contraceptives, Oral; Cyclohexanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; HIV Infections; Humans; Lamivudine; Levonorgestrel; Male; Maraviroc; Midazolam; Middle Aged; Statistics as Topic; Triazoles; Zidovudine | 2008 |
Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers.
Topics: Adult; Anti-Anxiety Agents; Antifungal Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Half-Life; Humans; Injections, Intravenous; Ketoconazole; Male; Midazolam; Middle Aged; Triazoles | 2009 |
Investigation of the pharmacokinetic interactions of deferasirox, a once-daily oral iron chelator, with midazolam, rifampin, and repaglinide in healthy volunteers.
Topics: Adult; Anesthetics, Intravenous; Aryl Hydrocarbon Hydroxylases; Benzoates; Carbamates; Cross-Over Studies; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Deferasirox; Drug Interactions; Enzyme Inhibitors; Female; Humans; Hypoglycemic Agents; Iron Chelating Agents; Male; Midazolam; Piperidines; Rifampin; Triazoles | 2010 |
Determining the time course of CYP3A inhibition by potent reversible and irreversible CYP3A inhibitors using A limited sampling strategy.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Half-Life; Humans; Male; Midazolam; Middle Aged; Pyrimidines; Ritonavir; Time Factors; Triazoles; Voriconazole; Young Adult | 2011 |
Effect of posaconazole on the pharmacokinetics of simvastatin and midazolam in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Male; Midazolam; Middle Aged; Simvastatin; Triazoles; Young Adult | 2012 |
A semiphysiological population pharmacokinetic model for dynamic inhibition of liver and gut wall cytochrome P450 3A by voriconazole.
Topics: Antifungal Agents; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Liver; Male; Midazolam; Models, Biological; Pyrimidines; Triazoles; Voriconazole | 2013 |
Safety, tolerability and pharmacokinetics of doravirine, a novel HIV non-nucleoside reverse transcriptase inhibitor, after single and multiple doses in healthy subjects.
Topics: Adult; Area Under Curve; Chromatography, Liquid; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Administration Schedule; Half-Life; Healthy Volunteers; Humans; Male; Midazolam; Middle Aged; Pyridones; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Triazoles | 2015 |
Clinical Confirmation that the Selective JAK1 Inhibitor Filgotinib (GLPG0634) has a Low Liability for Drug-drug Interactions.
Topics: Adult; Animals; Antirheumatic Agents; Biotransformation; CHO Cells; Cricetulus; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Glucuronosyltransferase; Humans; Janus Kinase 1; Male; Membrane Transport Proteins; Methotrexate; Microsomes, Liver; Midazolam; Middle Aged; Protein Kinase Inhibitors; Pyridines; Recombinant Proteins; Risk Assessment; Substrate Specificity; Transfection; Triazoles | 2016 |
Clinical Drug-Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib.
Topics: Adult; Anaplastic Lymphoma Kinase; Carbazoles; Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Midazolam; Middle Aged; Piperidines; Receptor Protein-Tyrosine Kinases; Rifampin; Treatment Outcome; Triazoles; Young Adult | 2017 |
Evaluation of the Drug-Drug Interaction Potential of Ensitrelvir Fumaric Acid with Cytochrome P450 3A Substrates in Healthy Japanese Adults.
Topics: Adult; Area Under Curve; COVID-19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Drug Interactions; East Asian People; Humans; Indazoles; Midazolam; Prednisolone; SARS-CoV-2; Triazines; Triazoles | 2023 |
11 other study(ies) available for triazoles and midazolam
| Article | Year |
|---|---|
Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for electrical brain stimulation in the rat?
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Carbolines; Chlordiazepoxide; Electric Stimulation; Hypothalamic Area, Lateral; Male; Midazolam; Phenylisopropyladenosine; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reinforcement, Psychology; Self Stimulation; Sensory Thresholds; Theophylline; Triazoles | 1991 |
Combining nefazodone and midazolam during ECT.
Topics: Antidepressive Agents, Second-Generation; Combined Modality Therapy; Drug Interactions; Dysthymic Disorder; Electroconvulsive Therapy; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Neuromuscular Depolarizing Agents; Piperazines; Succinylcholine; Thiopental; Treatment Outcome; Triazoles | 1999 |
Differential behavioral effects of low efficacy positive GABAA modulators in combination with benzodiazepines and a neuroactive steroid in rhesus monkeys.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Fluorobenzenes; GABA Modulators; Macaca mulatta; Midazolam; Pregnanediones; Receptors, GABA-A; Triazoles | 2006 |
Comparative effects of nonselective and subtype-selective gamma-aminobutyric acidA receptor positive modulators in the rat-conditioned emotional response test.
Topics: Amygdala; Animals; Conditioning, Operant; Emotions; Fluorobenzenes; Functional Laterality; GABA Agents; GABA Modulators; Ligands; Male; Microinjections; Midazolam; Rats; Receptors, GABA-A; Structure-Activity Relationship; Triazoles | 2007 |
Alpha1- and alpha2-containing GABAA receptor modulation is not necessary for benzodiazepine-induced hyperphagia.
Topics: Analysis of Variance; Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Energy Intake; Female; Fluorobenzenes; GABA Modulators; GABA-A Receptor Agonists; Hyperphagia; Male; Mice; Mice, Knockout; Midazolam; Random Allocation; Receptors, GABA-A; Triazoles | 2009 |
Differential modulation of cytochrome P450 activity and the effect of 1-aminobenzotriazole on hepatic transport in sandwich-cultured human hepatocytes.
Topics: Anti-Anxiety Agents; Anticholesteremic Agents; Atorvastatin; Bile; Biological Transport; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluorobenzenes; Hepatocytes; Heptanoic Acids; Humans; Isoenzymes; Midazolam; Models, Biological; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Time Factors; Triazoles | 2012 |
Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals.
Topics: Antifungal Agents; Azoles; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dioxolanes; Female; Heme; Humans; Hydroxylation; Iron; Itraconazole; Male; Metabolic Networks and Pathways; Midazolam; Stereoisomerism; Triazoles | 2012 |
In vitro and in vivo characterization of CYP inhibition by 1-aminobenzotriazole in rats.
Topics: Administration, Intravenous; Administration, Oral; Animals; Cytochrome P-450 Enzyme Inhibitors; Hepatocytes; Male; Microsomes, Liver; Midazolam; Rats; Triazoles | 2016 |
A simple method using anesthetics to test effects of sleep-inducing substances in mice.
Topics: Anesthesia; Anesthetics; Animals; Azepines; Butorphanol; Chlorpromazine; Drug Combinations; Imidazoles; Indenes; Isoflurane; Male; Medetomidine; Mice; Mice, Inbred ICR; Midazolam; Orexin Receptor Antagonists; Sleep Aids, Pharmaceutical; Triazoles | 2020 |
PBPK modeling of CYP3A and P-gp substrates to predict drug-drug interactions in patients undergoing Roux-en-Y gastric bypass surgery.
Topics: Acetaminophen; Administration, Oral; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Gastric Bypass; Gastrointestinal Absorption; Hepatobiliary Elimination; Humans; Intestinal Elimination; Metabolic Clearance Rate; Midazolam; Models, Biological; Obesity, Morbid; Postoperative Period; Triazoles; Verapamil | 2020 |
Leveraging Physiologically Based Pharmacokinetic Modeling and Experimental Data to Guide Dosing Modification of CYP3A-Mediated Drug-Drug Interactions in the Pediatric Population.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antifungal Agents; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Infant; Ketoconazole; Macrolides; Midazolam; Tandem Mass Spectrometry; Triazoles | 2021 |