triazoles has been researched along with methotrexate in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (17.07) | 29.6817 |
| 2010's | 17 (41.46) | 24.3611 |
| 2020's | 15 (36.59) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, RH; Hahn, MA | 1 |
| Brody, S; Kumlien, A; Paul, KG | 1 |
| Burstein, HJ; Winer, EP | 1 |
| Barfield, RC; Behm, FG; Burnette, K; Eldridge, P; Hale, GA; Handgretinger, R; Knapp, K | 1 |
| Burhenne, J; Foell, JL; Reiss, T; Rengelshausen, J; Staege, MS; Stiefel, M; Wawer, A | 1 |
| Chan, ES; Chen, JF; Cronstein, BN; Delano, DL; Desai, A; Fernandez, P; Friedman, SL; Montesinos, MC; Pillinger, MH; Reiss, AB; Schwarzschild, MA; Yee, H | 1 |
| Gottfredsson, M; Steingrímsdóttir, H | 1 |
| Ambudkar, SV; Manoharlal, R; Prasad, R; Prasad, T; Puri, N; Sharma, M; Shukla, S | 1 |
| Li, R; Liu, W; Wan, Z; Wang, X; Yang, J | 1 |
| Batteux, F; Chapron, C; Chéreau, C; Leconte, M; Ngô, C; Nicco, C; Weill, B | 1 |
| Bouboukas, G; Kalofonos, H; Koutras, A; Makatsoris, T; Onyenadum, A; Peroukides, S; Starakis, I | 1 |
| Fleishaker, DL; Garcia Meijide, JA; Goodrich, JM; Kohen, MD; Mayer, HB; Mebus, CA; Menon, S; Petrov, A; Stock, TC; Wang, X; Zeiher, BG | 1 |
| Kameda, H; Takeuchi, T | 1 |
| Huitema, AD; Schellens, JH; Schouten-van Meeteren, AY; van Eijkelenburg, NK; van Hasselt, JG | 1 |
| McNeil, C | 1 |
| Abulfadl, YS; Al-Omary, FA; Al-Rashood, ST; El-Hallouty, SM; El-Menshawi, BS; El-Messery, SM; El-Subbagh, HI; Fayad, W; Habib, el-SE; Hassan, GS; Mohamed, KM; Shabayek, MI | 1 |
| Barba, M; Del Medico, P; Di Lauro, L; Giannarelli, D; Laudadio, L; Maugeri-Saccà, M; Pizzuti, L; Sergi, D; Tomao, S; Vici, P | 1 |
| Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T | 1 |
| Desrivot, J; Harrison, P; Namour, F; Tasset, C; Van der Aa, A; van't Klooster, G | 1 |
| Almajed, MM; Esfahani, K; Panasci, L; Pelmus, M | 1 |
| Akhtar, S; Desai, A; Goldwater, R; Han, D; Howieson, C; Kowalski, D; Lademacher, C; Lasseter, KC; Rammelsberg, D; Townsend, R; Yamazaki, T | 1 |
| Cseuz, R; Greenwald, M; Harrison, P; Kavanaugh, A; Kremer, J; Ponce, L; Reshetko, OV; Stanislavchuk, M; Tasset, C; Van der Aa, A; Vanhoutte, F | 1 |
| Alten, R; Enríquez-Sosa, F; Greenwald, M; Harrison, P; Mazur, M; Pavlova, D; Tasset, C; Taylor, PC; Van der Aa, A; Vanhoutte, F; Westhovens, R | 1 |
| Galien, R; Mazur, M; Meuleners, L; Namour, F; Stanislavchuk, M; van 't Klooster, G; Van der Aa, A; Vanhoutte, F; Voloshyn, O | 1 |
| Abdo, M; Fekry, E; Makary, S | 1 |
| Genovese, M; Harrison, P; Kavanaugh, A; Meuleners, L; Tasset, C; Van der Aa, A; Westhovens, R | 1 |
| Benesch, M; Egger, M; Flaschberger, S; Gorkiewicz, G; Karastaneva, A; Kohlmaier, B; Lackner, H; Marterer, R; Seidel, M; Sperl, D; Strenger, V; Trobisch, A; Urban, C | 1 |
| Lee, YH; Song, GG | 4 |
| Lee, YH; Sung, YK | 1 |
| Amano, K; Atsumi, T; Bartok, B; de Vlam, K; Gao, J; Genovese, MC; Gottenberg, JE; Guo, Y; Ishiguro, N; Kalunian, K; Kondo, A; Matsubara, T; Pechonkina, A; Sugiyama, E; Sundy, JS; Takeuchi, T; Tanaka, Y; Tasset, C; Walker, D; Yamaoka, K | 1 |
| Atsumi, T; Bartok, B; Burmester, GR; Ching, DWT; Chopra, A; Guo, Y; Jahreis, A; Kay, J; Landewé, RB; Matzkies, F; Messina, OD; Mozaffarian, N; Rigby, WFC; Stohl, W; Sundy, JS; Tasset, C; van der Heijde, D; Westhovens, R; Yin, Z | 1 |
| Bae, SC; Baraf, HSB; Bartok, B; Combe, B; Genovese, MC; Guo, Y; Jahreis, A; Keystone, EC; Kivitz, A; Kumar, U; Landewé, RBM; Matzkies, F; Mozaffarian, N; Nash, P; Simon, JA; Sundy, JS; Tanaka, Y; Tasset, C; van der Heijde, D; Ye, L | 1 |
| Alten, R; An, D; Besuyen, R; Genovese, MC; Greenwald, M; Kavanaugh, A; Lee, SJ; Meuleners, L; Spindler, AJ; Stanislavchuk, M; Sundy, JS; Tan, Y; Westhovens, RR; Winthrop, KL; Ye, L | 1 |
| Nash, P | 1 |
| Adami, G; Aletaha, D; Bartok, B; Bird, P; Buch, MH; Burmester, GR; Gaujoux-Viala, C; Guo, Y; Hendrikx, T; Matsumoto, A; Messina, OD; Westhovens, R; Yin, Z | 1 |
| Amano, K; Atsumi, T; Bae, SC; Bartok, B; Combe, BG; Guo, Y; Ishiguro, N; Keystone, EC; Kivitz, AJ; Kondo, A; Matsubara, T; Matzkies, F; Nash, P; Pechonkina, A; Sugiyama, E; Sundy, JS; Takeuchi, T; Tanaka, Y; Tasset, C; Yamaoka, K; Ye, L | 1 |
| Amano, K; Atsumi, T; Bartok, B; Burmester, GR; Ching, DWT; Guo, Y; Ishiguro, N; Kondo, A; Matsubara, T; Messina, OD; Pechonkina, A; Sugiyama, E; Sundy, JS; Takeuchi, T; Tanaka, Y; Tasset, C; Westhovens, R; Yamaoka, K; Yin, Z | 1 |
| Bingham, CO; Combe, B; Hu, H; Khalid, JM; Lee, SJ; Nash, P; Walker, D; Ye, L | 1 |
6 review(s) available for triazoles and methotrexate
| Article | Year |
|---|---|
New combinations with Herceptin in metastatic breast cancer.
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Deoxycytidine; Doxorubicin; Drug Interactions; Drug Synergism; Epirubicin; Female; Fluorouracil; Gemcitabine; Heart Diseases; Hematologic Diseases; Humans; Methotrexate; Neoplasm Metastasis; Nitriles; Organoplatinum Compounds; Paclitaxel; Tamoxifen; Thiotepa; Trastuzumab; Treatment Outcome; Triazoles; Vinblastine; Vinorelbine | 2001 |
Comparison of the efficacy and safety of tofacitinib and filgotinib in patients with active rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bayes Theorem; Drug Therapy, Combination; Humans; Methotrexate; Network Meta-Analysis; Piperidines; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2020 |
Comparative efficacy and safety of 100 mg and 200 mg filgotinib administered to patients with active rheumatoid arthritis: A Bayesian network meta-analysis of randomized controlled trials
.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bayes Theorem; Drug Therapy, Combination; Humans; Janus Kinase 1; Methotrexate; Network Meta-Analysis; Pyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2020 |
Comparative efficacy and safety of tofacitinib, baricitinib, upadacitinib, and filgotinib in active rheumatoid arthritis refractory to biologic disease-modifying antirheumatic drugs.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Biological Products; Heterocyclic Compounds, 3-Ring; Humans; Methotrexate; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sulfonamides; Treatment Outcome; Triazoles | 2021 |
Comparative study of the efficacy and safety of tofacitinib, baricitinib, upadacitinib, and filgotinib versus methotrexate for disease-modifying antirheumatic drug-naïve patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Bayes Theorem; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; Humans; Methotrexate; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Sulfonamides; Treatment Outcome; Triazoles | 2021 |
Clinical use of Jak 1 inhibitors for rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; Humans; Janus Kinase 1; Janus Kinase Inhibitors; Methotrexate; Practice Patterns, Physicians'; Pyridines; Triazoles | 2021 |
15 trial(s) available for triazoles and methotrexate
| Article | Year |
|---|---|
Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Area Under Curve; Arthritis, Rheumatoid; CCR5 Receptor Antagonists; Constipation; Cyclohexanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Maraviroc; Metabolic Clearance Rate; Methotrexate; Middle Aged; Nausea; Treatment Failure; Triazoles; Young Adult | 2012 |
Clinical Confirmation that the Selective JAK1 Inhibitor Filgotinib (GLPG0634) has a Low Liability for Drug-drug Interactions.
Topics: Adult; Animals; Antirheumatic Agents; Biotransformation; CHO Cells; Cricetulus; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Glucuronosyltransferase; Humans; Janus Kinase 1; Male; Membrane Transport Proteins; Methotrexate; Microsomes, Liver; Midazolam; Middle Aged; Protein Kinase Inhibitors; Pyridines; Recombinant Proteins; Risk Assessment; Substrate Specificity; Transfection; Triazoles | 2016 |
Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects.
Topics: Adult; Area Under Curve; Atorvastatin; Digoxin; Female; Healthy Volunteers; Humans; Male; Membrane Transport Proteins; Metformin; Methotrexate; Middle Aged; Nitriles; Pyridines; Triazoles; Young Adult | 2017 |
Filgotinib (GLPG0634/GS-6034), an oral selective JAK1 inhibitor, is effective as monotherapy in patients with active rheumatoid arthritis: results from a randomised, dose-finding study (DARWIN 2).
Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemoglobins; Humans; Infections; Janus Kinase 1; Male; Methotrexate; Middle Aged; Protein Kinase Inhibitors; Pyridines; Retreatment; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome; Triazoles | 2017 |
Filgotinib (GLPG0634/GS-6034), an oral JAK1 selective inhibitor, is effective in combination with methotrexate (MTX) in patients with active rheumatoid arthritis and insufficient response to MTX: results from a randomised, dose-finding study (DARWIN 1).
Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Hemoglobins; Humans; Infections; Janus Kinase 1; Male; Methotrexate; Middle Aged; Protein Kinase Inhibitors; Pyridines; Severity of Illness Index; Surveys and Questionnaires; Triazoles | 2017 |
Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK-1 Inhibitor, After Short-Term Treatment of Rheumatoid Arthritis: Results of Two Randomized Phase IIa Trials.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Janus Kinase 1; Male; Methotrexate; Middle Aged; Pyridines; Treatment Outcome; Triazoles; Young Adult | 2017 |
Effect of filgotinib, a selective JAK 1 inhibitor, with and without methotrexate in patients with rheumatoid arthritis: patient-reported outcomes.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Janus Kinase 1; Male; Methotrexate; Middle Aged; Patient Reported Outcome Measures; Protein Kinase Inhibitors; Pyridines; Treatment Outcome; Triazoles | 2018 |
Efficacy and safety of filgotinib in Japanese patients with refractory rheumatoid arthritis: Subgroup analyses of a global phase 3 study (FINCH 2).
Topics: Adult; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Finches; Humans; Japan; Methotrexate; Pyridines; Treatment Outcome; Triazoles | 2022 |
Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Finches; Humans; Methotrexate; Pyridines; Treatment Outcome; Triazoles | 2021 |
Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial.
Topics: Adalimumab; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Pyridines; Triazoles | 2021 |
Safety and Efficacy of Filgotinib: Up to 4-year Results From an Open-label Extension Study of Phase II Rheumatoid Arthritis Programs.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Humans; Male; Methotrexate; Pyridines; Treatment Outcome; Triazoles | 2021 |
Efficacy and safety of filgotinib in methotrexate-naive patients with rheumatoid arthritis with poor prognostic factors: post hoc analysis of FINCH 3.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Methotrexate; Prognosis; Pyridines; Treatment Outcome; Triazoles | 2021 |
Efficacy and safety of filgotinib in combination with methotrexate in Japanese patients with active rheumatoid arthritis who have an inadequate response to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 1).
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Finches; Humans; Japan; Methotrexate; Pyridines; Treatment Outcome; Triazoles | 2022 |
Efficacy and safety of filgotinib alone and in combination with methotrexate in Japanese patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 3)
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Finches; Humans; Japan; Methotrexate; Pyridines; Treatment Outcome; Triazoles | 2022 |
The impact of filgotinib on patient-reported outcomes and health-related quality of life for patients with active rheumatoid arthritis: a post hoc analysis of Phase 3 studies.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Humans; Methotrexate; Patient Reported Outcome Measures; Pyridines; Quality of Life; Treatment Outcome; Triazoles | 2022 |
20 other study(ies) available for triazoles and methotrexate
| Article | Year |
|---|---|
Pharmacology of 3,5-diamino-1,24-triazole (guanazole). 1. Antitumor activity of guanazole.
Topics: Amines; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Depression, Chemical; Female; Hydroxyurea; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Male; Mast-Cell Sarcoma; Methotrexate; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Plasmacytoma; Structure-Activity Relationship; Triazoles | 1972 |
Studies on eosinophil granulocytes. II. The effect of cytostatics on the uterine response to oestrogen.
Topics: Animals; Castration; Catalase; Chloramphenicol; Eosinophils; Estrogens; Female; Fluorouracil; Liver; Mercaptopurine; Methotrexate; Mice; Organ Size; Peroxidases; Pyridoxine; Streptomycin; Triazoles; Uterus | 1966 |
Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia.
Topics: AC133 Antigen; Amphotericin B; Antifungal Agents; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Caspofungin; Child; Combined Modality Therapy; Contraindications; Dexamethasone; Drug Therapy, Combination; Echinocandins; Glycoproteins; Humans; Immunomagnetic Separation; Lipopeptides; Male; Mercaptopurine; Methotrexate; Peptides; Peptides, Cyclic; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Recurrence; Remission Induction; Salvage Therapy; Transplantation, Autologous; Transplantation, Homologous; Triazoles; Vincristine; Voriconazole; Zygomycosis | 2007 |
Successful treatment with voriconazole of Aspergillus brain abscess in a boy with medulloblastoma.
Topics: Administration, Oral; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillus fumigatus; Brain Abscess; Carboplatin; Cerebral Ventricle Neoplasms; Child; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Cyclophosphamide; Diagnostic Errors; Etoposide; Humans; Immunocompromised Host; Infusions, Intravenous; Lomustine; Male; Medulloblastoma; Methotrexate; Neoplasm Recurrence, Local; Neuroaspergillosis; Pyrimidines; Surgical Wound Infection; Triazoles; Vincristine; Voriconazole | 2007 |
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Cell Line; Chromatography, High Pressure Liquid; Ethanol; Hepatocytes; Humans; Liver Cirrhosis; Matrix Metalloproteinases, Membrane-Associated; Methotrexate; Mice; Mice, Inbred C57BL; Rats; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Triazines; Triazoles | 2006 |
Disseminated invasive aspergillosis in a patient with acute leukaemia.
Topics: Acute Kidney Injury; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Bacteremia; Caspofungin; Chlamydophila Infections; Chlamydophila pneumoniae; Doxorubicin; Drug Resistance, Multiple, Fungal; Drug Therapy, Combination; Echinocandins; Fatal Outcome; Female; Humans; Immunocompromised Host; Lipopeptides; Liposomes; Lung Diseases, Fungal; Medical Futility; Methotrexate; Middle Aged; Neuroaspergillosis; Peptides, Cyclic; Pneumonia, Bacterial; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Streptococcal Infections; Triazoles; Vincristine; Voriconazole | 2006 |
Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals.
Topics: Anisomycin; Antifungal Agents; Biological Transport; Candida albicans; Curcumin; Cycloheximide; Drug Synergism; Enzyme Inhibitors; Fluconazole; Itraconazole; Ketoconazole; Methotrexate; Miconazole; Multidrug Resistance-Associated Proteins; Pyrimidines; Rhodamines; Saccharomyces cerevisiae; Triazoles; Voriconazole | 2009 |
In vitro interactions between antifungals and methotrexate against Aspergillus spp.
Topics: Amphotericin B; Antifungal Agents; Aspergillus; Drug Interactions; Itraconazole; Methotrexate; Microbial Sensitivity Tests; Naphthalenes; Pyrimidines; Terbinafine; Triazoles; Voriconazole | 2009 |
Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo.
Topics: Adult; Anastrozole; Animals; Antineoplastic Agents; Biopsy; Case-Control Studies; Cell Proliferation; Cell Survival; Cells, Cultured; Endometriosis; Endometrium; Female; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Nitriles; Progesterone; Transplantation, Heterologous; Triazoles; Uterine Diseases | 2010 |
Prolonged survival of neoplastic meningitis from breast cancer with letrozole and intrathecal methotrexate: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Injections, Spinal; Letrozole; Meningitis; Methotrexate; Middle Aged; Nitriles; Prognosis; Survival Rate; Triazoles | 2011 |
What is the future of CCR5 antagonists in rheumatoid arthritis?
Topics: Arthritis, Rheumatoid; Cyclohexanes; Female; Humans; Male; Methotrexate; Triazoles | 2012 |
Severe skin toxicity in pediatric oncology patients treated with voriconazole and concomitant methotrexate.
Topics: Adolescent; Antibiotic Prophylaxis; Antifungal Agents; Antimetabolites, Antineoplastic; Aspergillosis; Cheilitis; Child; Child, Preschool; Dermatitis, Photoallergic; Drug Therapy, Combination; Female; Hematologic Neoplasms; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Male; Methotrexate; Pyrimidines; Skin; Treatment Outcome; Triazoles; Voriconazole | 2013 |
Preventing graft-versus-host disease: transplanters glimpse hope beyond immunosuppressants.
Topics: Acute Disease; Bone Marrow Transplantation; Boronic Acids; Bortezomib; Chronic Disease; Clinical Trials as Topic; Cyclohexanes; Cyclophosphamide; Cyclosporine; Evidence-Based Medicine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Hydroxamic Acids; Immunosuppressive Agents; Maraviroc; Methotrexate; Pentostatin; Peripheral Blood Stem Cell Transplantation; Pyrazines; Quality of Life; Tacrolimus; Triazoles; Vorinostat | 2013 |
Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study.
Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Screening Assays, Antitumor; Female; Folic Acid Antagonists; Male; Methotrexate; Models, Molecular; Protein Conformation; Schistosoma mansoni; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazoles | 2013 |
Letrozole combined with gonadotropin-releasing hormone analog for metastatic male breast cancer.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Docetaxel; Epirubicin; Estrogen Receptor Modulators; Estrogens; Fluorouracil; Gonadotropin-Releasing Hormone; Goserelin; Humans; Kaplan-Meier Estimate; Letrozole; Male; Mastectomy, Modified Radical; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Progesterone; Radiotherapy, Adjuvant; Tamoxifen; Taxoids; Triazoles | 2013 |
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine | 2014 |
Complete response and long-term survival of leptomeningeal carcinomatosis from breast cancer with maintenance endocrine therapy.
Topics: Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Letrozole; Meningeal Carcinomatosis; Methotrexate; Nitriles; Spinal Neoplasms; Triazoles | 2016 |
Oxidative stress burden inhibits spermatogenesis in adult male rats: testosterone protective effect.
Topics: Aging; Animals; Biomarkers; Body Weight; Estradiol; Follicle Stimulating Hormone; Grape Seed Extract; Inflammation; Letrozole; Male; Methotrexate; Nitriles; Organ Size; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Seminiferous Tubules; Sperm Count; Sperm Motility; Spermatogenesis; Testosterone; Triazoles | 2018 |
Invasive mucormycosis during treatment for acute lymphoblastic leukaemia-successful management of two life-threatening diseases.
Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Invasive Fungal Infections; Lung Diseases, Fungal; Male; Mercaptopurine; Methotrexate; Mucorales; Mucormycosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Triazoles; Vincristine | 2020 |
Relative efficacy and safety of tofacitinib, baricitinib, upadacitinib, and filgotinib in comparison to adalimumab in patients with active rheumatoid arthritis.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Bayes Theorem; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; Humans; Methotrexate; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sulfonamides; Treatment Outcome; Triazoles | 2020 |