Page last updated: 2024-08-24

triazoles and losartan potassium

triazoles has been researched along with losartan potassium in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's1 (3.33)18.2507
2000's7 (23.33)29.6817
2010's13 (43.33)24.3611
2020's8 (26.67)2.80

Authors

AuthorsStudies
Thorling, EB1
Cole, K; Kohn, EC; Sandeen, MA; Volpe, DA1
Brookins, J; Fisher, JW1
Blakey, D; Heflich, RH; Jacobs, A; Jacobsen, SD; Morita, T; Nohmi, T; O'Donovan, MR; Sasaki, YF; Sofuni, T; Tice, R; Tweats, DJ1
Steensma, DP; Tefferi, A1
Chaigneau, L; Demarchi, M; Lorgis, V; Maurina, T; Meaux-Ruault, N; N'guyen, T; Pivot, X; Stein, U; Thiery-Vuillemin, A; Villanueva, C1
Ohyashiki, K1
Brewster, UC; McPhedran, P; Yusuf, B1
Fernández de Henestrosa, AR; García, C; Guzmán, A; Marcos, R; Marín, AP; Ruiz, MT; Tortajada, A1
Rempe, DA; Zhao, Y1
Chrétien, S; Fucharoen, S; Goupille, O; Granger, M; Kadri, Z; Leboulch, P; Lefèvre, C; Maouche-Chrétien, L; Penglong, T1
Guinea de Castro, JM; Moreno de Gusmão, B; Oiartzabal, I; Perez-Persona, E1
Tohyama, K1
Nie, J; Wang, F; Wang, H; Zhang, C1
Ellinghaus, P; Flamme, I; Jeske, M; Keldenich, J; Oehme, F; Thuss, U1
Church, TJ; Frigon, NL; Lariosa-Willingham, K; Leonoudakis, D; Miller, JL; Punnonen, J; Spencer, JR; Tettenborn, CS1
Gupta, N; Wish, JB1
Frigon, NL; Miller, JL; Pandolfo, M; Punnonen, J; Rai, M; Spencer, JR1
Arens, ER; Böttcher, M; Kaiser, A; Kubitza, D; Lentini, S; Thuss, U; van der Mey, D; Wensing, G1
Gu, J; Jiang, Z; Li, Z; Wu, Y; You, Q; Zhang, X1
Akizawa, T; Arai, M; Hirakata, H; Koretomo, R; Matsui, A; Nangaku, M; Yamaguchi, T1
Deai, K; Fukui, K; Kobayashi, H; Matsui, T; Matsuo, A; Matsushita, M; Nangaku, M; Shinozaki, Y; Tanaka, T; Yoshiuchi, H1
Kaiser, A; Kapsa, S; Lentini, S; Matsuno, K; van der Mey, D1
Kittikulsuth, W; Li, L; Morisawa, N; Nakano, D; Nishiyama, A; Ohsaki, H; Suzuki, N; Yamamoto, M; Zhang, A1
Gerisch, M; Jungmann, NA; Kaiser, A; Lentini, S; Radtke, M; Schulz, S; van der Mey, D; Yoshikawa, K1
Fukui, K; Kobayashi, H; Matsuo, A; Matsushita, M; Shinozaki, Y; Yoshiuchi, H1
Akizawa, T; Hayasaki, T; Hayashi, Y; Matsuda, Y; Nobori, K; Taki, K; Yamamoto, H1
Fukui, K; Nangaku, M; Tanaka, T1
Akizawa, T; Fujikawa, R; Fujioka, M; Nagao, Y1
Hartner, A; Schley, G1

Reviews

6 review(s) available for triazoles and losartan potassium

ArticleYear
Risk-based management of myelodysplastic syndrome.
    Oncology (Williston Park, N.Y.), 2007, Volume: 21, Issue:1

    Topics: Anemia, Sideroblastic; Antilymphocyte Serum; Azacitidine; Benzoates; Decitabine; Deferasirox; DNA Modification Methylases; Enzyme Inhibitors; Erythropoietin; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Histone Deacetylase Inhibitors; Humans; Immunosuppressive Agents; Interleukin-11; Iron Chelating Agents; Lenalidomide; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Prognosis; Risk; Stem Cell Transplantation; Thalidomide; Triazoles

2007
[Development trend in new therapeutic approaches for anemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:3

    Topics: Anemia; Benzoates; Clinical Trials as Topic; Darbepoetin alfa; Deferasirox; Erythropoietin; Hematinics; Humans; Iron Chelating Agents; Iron Overload; Lenalidomide; Myelodysplastic Syndromes; Neoplasms; Thalidomide; Triazoles

2008
[Myelodysplastic syndromes: treatment strategy up-to-date].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:1

    Topics: Antilymphocyte Serum; Azacitidine; Benzoates; Cyclosporine; Cytarabine; Deferasirox; Disease Progression; Drug Discovery; Drug Therapy, Combination; Erythropoietin; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Iron Chelating Agents; Lenalidomide; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Quality of Life; Risk Assessment; Thalidomide; Triazoles

2014
Protective factors in diabetic retinopathy: focus on blood-retinal barrier.
    Discovery medicine, 2014, Volume: 18, Issue:98

    Topics: Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Erythropoietin; Fenofibrate; Humans; Insulin-Like Growth Factor Binding Protein 3; Macular Edema; Protective Factors; Pyrazines; Sitagliptin Phosphate; Triazoles; Vascular Endothelial Growth Factor A

2014
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors: A Potential New Treatment for Anemia in Patients With CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 69, Issue:6

    Topics: Anemia; Barbiturates; Clinical Trials as Topic; Enzyme Inhibitors; Erythropoietin; Glycine; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoquinolines; Pyrazoles; Renal Insufficiency, Chronic; Triazoles

2017
Treatment of anemia associated with chronic kidney disease with the HIF prolyl hydroxylase inhibitor enarodustat: A review of the evidence.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2022, Volume: 26, Issue:4

    Topics: Anemia; Erythropoietin; Hematinics; Humans; N-substituted Glycines; Prolyl-Hydroxylase Inhibitors; Pyridines; Renal Insufficiency, Chronic; Triazoles

2022

Trials

4 trial(s) available for triazoles and losartan potassium

ArticleYear
First-in-man-proof of concept study with molidustat: a novel selective oral HIF-prolyl hydroxylase inhibitor for the treatment of renal anaemia.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:7

    Topics: Administration, Oral; Adult; Anemia; Area Under Curve; Erythropoietin; Half-Life; Healthy Volunteers; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Male; Prolyl-Hydroxylase Inhibitors; Proof of Concept Study; Pyrazoles; Renal Insufficiency, Chronic; Single-Blind Method; Triazoles; Young Adult

2018
A Placebo-Controlled, Randomized Trial of Enarodustat in Patients with Chronic Kidney Disease Followed by Long-Term Trial.
    American journal of nephrology, 2019, Volume: 49, Issue:2

    Topics: Aged; Aged, 80 and over; Anemia; Dose-Response Relationship, Drug; Double-Blind Method; Erythropoietin; Female; Ferritins; Follow-Up Studies; Hematinics; Hemoglobins; Hepcidins; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Japan; Kidney; Male; Middle Aged; N-substituted Glycines; Placebos; Pyridines; Renal Insufficiency, Chronic; Time Factors; Treatment Outcome; Triazoles

2019
Effects of oral iron and calcium supplement on the pharmacokinetics and pharmacodynamics of molidustat: an oral HIF-PH inhibitor for the treatment of renal anaemia.
    European journal of clinical pharmacology, 2020, Volume: 76, Issue:2

    Topics: Administration, Oral; Adult; Anemia; Area Under Curve; Calcium; Cross-Over Studies; Dietary Supplements; Drug Administration Schedule; Drug Interactions; Erythropoietin; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Iron; Male; Middle Aged; Pyrazoles; Time Factors; Triazoles; Young Adult

2020
Molidustat for the treatment of anemia in Japanese patients undergoing peritoneal dialysis: a single-arm, open-label, phase 3 study.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2022, Volume: 26, Issue:2

    Topics: Anemia; Erythropoietin; Hematinics; Hemoglobins; Humans; Japan; Peritoneal Dialysis; Pyrazoles; Renal Dialysis; Renal Insufficiency, Chronic; Treatment Outcome; Triazoles

2022

Other Studies

20 other study(ies) available for triazoles and losartan potassium

ArticleYear
A comparison of the cobalt, methylene blue, zinc, arsenite and amino triazole effect on erythropoietin production.
    British journal of haematology, 1973, Volume: 25, Issue:1

    Topics: Animals; Arsenic; Biological Assay; Cobalt; Erythropoietin; Female; Hypoxia; Iron; Iron Isotopes; Male; Methylene Blue; Mice; Polycythemia; Rabbits; Stimulation, Chemical; Triazoles; Zinc

1973
In vitro and in vivo myelotoxicity of CAI to human and murine hematopoietic progenitor cells.
    American journal of hematology, 1995, Volume: 50, Issue:4

    Topics: Animals; Bone Marrow Cells; Cell Division; Erythroid Precursor Cells; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Leukocyte Count; Macrophages; Mice; Platelet Count; Recombinant Proteins; Spleen; Triazoles

1995
Adenosine A(2A) and A(2B) receptor activation of erythropoietin production.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:5

    Topics: Adenosine; Alkaloids; Benzophenanthridines; Carcinoma, Hepatocellular; Enzyme Activation; Erythropoietin; Humans; Liver Neoplasms; Phenanthridines; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Xanthines

2001
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards.
    Mutation research, 2007, Feb-03, Volume: 627, Issue:1

    Topics: Aniline Compounds; Animals; Body Temperature; Bone Marrow Cells; Erythropoietin; Guidelines as Topic; Hyperthermia, Induced; Micronucleus Tests; Mutagenicity Tests; Mutagens; Naphthoquinones; Phenol; Phenylhydrazines; Pyridines; Reserpine; Rodentia; Sensitivity and Specificity; Triazoles

2007
Anticancer therapy in patients with porphyrias: evidence today.
    Expert opinion on drug safety, 2008, Volume: 7, Issue:2

    Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Docetaxel; Epoetin Alfa; Erythropoietin; Female; Granulocyte Colony-Stimulating Factor; Hematinics; Humans; Letrozole; Middle Aged; Nitriles; Porphyria, Acute Intermittent; Porphyria, Variegate; Recombinant Proteins; Risk Assessment; Taxoids; Triazoles; Uterine Neoplasms

2008
Hypocalcemia in a dialysis patient treated with deferasirox for iron overload.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:3

    Topics: Adult; Anemia, Sickle Cell; Benzoates; Deferasirox; Erythropoietin; Female; Humans; Hypertension; Hypocalcemia; Iron Chelating Agents; Iron Overload; Kidney Failure, Chronic; Peritoneal Dialysis; Transfusion Reaction; Triazoles

2008
Formation of micronucleated erythrocytes in mouse bone-marrow under conditions of hypothermia is not associated with stimulation of erythropoiesis.
    Mutation research, 2008, Oct-30, Volume: 656, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Body Temperature; Bone Marrow Cells; Chlorpromazine; Erythrocytes; Erythropoiesis; Erythropoietin; Hypothermia; Hypothermia, Induced; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Pyridines; Time Factors; Triazoles

2008
Prophylactic neuroprotection against stroke: low-dose, prolonged treatment with deferoxamine or deferasirox establishes prolonged neuroprotection independent of HIF-1 function.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:6

    Topics: Animals; Astrocytes; Benzoates; Brain; Cyclic AMP Response Element-Binding Protein; Deferasirox; Deferoxamine; Erythropoietin; Extracellular Signal-Regulated MAP Kinases; Gene Deletion; Hypoxia-Inducible Factor 1; Iron Chelating Agents; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-akt; Stroke; Triazoles

2011
BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7.
    Biochemical and biophysical research communications, 2012, Dec-07, Volume: 429, Issue:1-2

    Topics: Azepines; Cell Line, Tumor; Cell Proliferation; Erythroid Cells; Erythropoiesis; Erythropoietin; Humans; Leukemia, Erythroblastic, Acute; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; Triazoles

2012
[Transfusional independence in a patient with refractory anemia with excess blasts-2 refractory to 5-azacitidine treated with deferasirox and colony stimulating factors].
    Medicina clinica, 2014, Jan-21, Volume: 142, Issue:2

    Topics: Aged; Anemia, Refractory, with Excess of Blasts; Azacitidine; Benzoates; Blood Transfusion; Chelation Therapy; Combined Modality Therapy; Deferasirox; Disease Progression; Drug Resistance; Epoetin Alfa; Erythropoietin; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Iron; Iron Chelating Agents; Leukemia, Myeloid, Acute; Male; Recombinant Proteins; Triazoles

2014
Mimicking hypoxia to treat anemia: HIF-stabilizer BAY 85-3934 (Molidustat) stimulates erythropoietin production without hypertensive effects.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Anemia; Animals; Erythropoietin; Female; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Macaca fascicularis; Male; Pyrazoles; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Triazoles; Up-Regulation

2014
Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor.
    Molecular pharmacology, 2015, Volume: 88, Issue:2

    Topics: Animals; Biological Availability; Blood-Brain Barrier; Brain; Caco-2 Cells; Cells, Cultured; Cytokine Receptor Common beta Subunit; Erythropoietin; HEK293 Cells; Humans; Neurons; Pyrimidines; Rats; Receptors, Erythropoietin; Signal Transduction; Triazoles

2015
Erythropoietin and small molecule agonists of the tissue-protective erythropoietin receptor increase FXN expression in neuronal cells in vitro and in Fxn-deficient KIKO mice in vivo.
    Neuropharmacology, 2017, Sep-01, Volume: 123

    Topics: Adult; Animals; Cells, Cultured; Cerebral Cortex; Erythropoietin; Female; Frataxin; Friedreich Ataxia; Histone Deacetylase Inhibitors; Humans; Iron-Binding Proteins; Leukocytes, Mononuclear; Male; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Neurons; Neuroprotective Agents; Pyrimidines; Receptors, Erythropoietin; Recombinant Proteins; Triazoles; Young Adult

2017
Click Chemistry-Based Discovery of [3-Hydroxy-5-(1 H-1,2,3-triazol-4-yl)picolinoyl]glycines as Orally Active Hypoxia-Inducing Factor Prolyl Hydroxylase Inhibitors with Favorable Safety Profiles for the Treatment of Anemia.
    Journal of medicinal chemistry, 2018, 06-28, Volume: 61, Issue:12

    Topics: Administration, Oral; Anemia; Animals; Cisplatin; Click Chemistry; Erythropoietin; Female; Fluorescence Polarization; Glycine; Hemoglobins; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Prolyl-Hydroxylase Inhibitors; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles

2018
JTZ-951 (enarodustat), a hypoxia-inducibe factor prolyl hydroxylase inhibitor, stabilizes HIF-α protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor.
    European journal of pharmacology, 2019, Sep-15, Volume: 859

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Dose-Response Relationship, Drug; Erythropoiesis; Erythropoietin; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; N-substituted Glycines; Prolyl-Hydroxylase Inhibitors; Protein Stability; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Triazoles; Vascular Endothelial Growth Factor A

2019
Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice.
    Journal of pharmacological sciences, 2020, Volume: 144, Issue:4

    Topics: Acute Kidney Injury; Adenine; Anemia; Animals; Disease Models, Animal; Erythropoietin; Hypoxia-Inducible Factor 1; Male; Mice, Inbred C57BL; Prolyl-Hydroxylase Inhibitors; Pyrazoles; Triazoles

2020
Drug-drug interaction of atazanavir on UGT1A1-mediated glucuronidation of molidustat in human.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:3

    Topics: Adult; Atazanavir Sulfate; Drug Interactions; Erythropoietin; Glucuronides; Glucuronosyltransferase; Humans; Male; Middle Aged; Pyrazoles; Triazoles; Young Adult

2021
JTZ-951 (enarodustat), a hypoxia-inducible factor prolyl hydroxylase inhibitor, improves iron utilization and anemia of inflammation: Comparative study against recombinant erythropoietin in rat.
    European journal of pharmacology, 2021, May-05, Volume: 898

    Topics: Anemia, Iron-Deficiency; Animals; Arthritis, Experimental; Biomarkers; Enzyme Inhibitors; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Hematinics; Hepcidins; Hypoxia-Inducible Factor-Proline Dioxygenases; Iron; N-substituted Glycines; Pyridines; Rats, Inbred Lew; Recombinant Proteins; Triazoles

2021
Enarodustat to treat anemia in chronic kidney disease.
    Drugs of today (Barcelona, Spain : 1998), 2021, Volume: 57, Issue:8

    Topics: Anemia; Erythropoietin; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; N-substituted Glycines; Pyridines; Renal Insufficiency, Chronic; Triazoles

2021
The prolyl hydroxylase inhibitor molidustat fails to restore erythropoietin production in the fibrotic kidney.
    Acta physiologica (Oxford, England), 2022, Volume: 235, Issue:4

    Topics: Erythropoietin; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Kidney; Prolyl-Hydroxylase Inhibitors; Pyrazoles; Renal Insufficiency, Chronic; Triazoles

2022