Page last updated: 2024-08-24

triazoles and ketorolac

triazoles has been researched along with ketorolac in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Maruta, H; Nguyen, BCQ; Shahinozzaman, MD; Takahashi, H; Tawata, S; Uto, Y1
Adrian, TE; Albawardi, A; Almarzooqi, S; Haneefa, S; Hennig, R; Imbaraj, E; Maruta, H; Nemmar, A; Subramanya, S; Zaaba, NE1
Ahmed, S; Emran, R; Shahinozzaman, M; Tawata, S1

Other Studies

4 other study(ies) available for triazoles and ketorolac

ArticleYear
News drugs and dosage forms.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, Jul-15, Volume: 71, Issue:14

    Topics: Anti-HIV Agents; Antifungal Agents; Atazanavir Sulfate; Drug Combinations; Humans; Ketorolac; Oligopeptides; Phenylephrine; Pyridines; Testosterone; Triazoles

2014
1,2,3-Triazolyl ester of Ketorolac: A "Click Chemistry"-based highly potent PAK1-blocking cancer-killer.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Click Chemistry; Cyclooxygenase 2 Inhibitors; Esters; Humans; Ketorolac; p21-Activated Kinases; Protein Kinase Inhibitors; Signal Transduction; Triazoles

2017
1,2,3-Triazolyl ester of ketorolac (15K), a potent PAK1 blocker, inhibits both growth and metastasis of orthotopic human pancreatic cancer xenografts in mice.
    Drug discoveries & therapeutics, 2019, Nov-14, Volume: 13, Issue:5

    Topics: Animals; Body Weight; Cell Line, Tumor; Cell Proliferation; Esters; Hemodynamics; Humans; Inhibitory Concentration 50; Ketorolac; Mice; Mice, Nude; Neoplasm Invasiveness; Triazoles; Xenograft Model Antitumor Assays

2019
Molecular modelling approaches predicted 1,2,3-triazolyl ester of ketorolac (15K) to be a novel allosteric modulator of the oncogenic kinase PAK1.
    Scientific reports, 2021, 09-01, Volume: 11, Issue:1

    Topics: 3T3 Cells; Allosteric Regulation; Animals; Esters; Ketorolac; Mice; Models, Molecular; Molecular Dynamics Simulation; Oncogenes; p21-Activated Kinases; Protein Conformation; Triazoles

2021