triazoles has been researched along with jnj-7706621 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 11 (78.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Connolly, PJ; Emanuel, S; Fuentes-Pesquera, A; Gruninger, RH; Hollister, B; Jolliffe, L; Kruger, WW; Lin, R; Middleton, SA; Napier, C; Rugg, CA; Wetter, SK | 1 |
| Connolly, PJ; Emanuel, S; Huang, S; Lin, R; Middleton, SA | 1 |
| Ambudkar, SV; Borowski, V; Butler, J; Calcagno, AM; Emanuel, S; Greenberger, LM; Middleton, SA; Rugg, CA; Seamon, JA | 1 |
| Brewster, ME; Danhier, F; Magotteaux, N; Préat, V; Ucakar, B | 1 |
| Bossemeyer, D; de Oliveira, TM; Engh, RA; Pflug, A | 1 |
| Hara, A; Kawai, G; Kimura, M; Matsuhashi, A; Nagano, A; Ohno, T; Okano, Y; Saio, M; Saitou, M; Shimizu, K; Takigami, I; Yamada, K | 1 |
| Baer, C; Breyssens, H; Brown, NR; Caballero, OL; Cebon, J; Endicott, J; Goding, CR; Hu, Y; John, T; Jones, EY; Kessler, BM; Knapp, S; Lu, M; Lu, X; Middleton, MR; Ratnayaka, I; Salter, V; Siebold, C; Sullivan, A; Sviderskaya, EV; Zhong, S | 1 |
| Bak, M; Duun-Henriksen, AK; Kirkegaard, T; Lykkesfeldt, AE; Lænkholm, AV; Pedersen, AM; Rasmussen, BB; Thomsen, MB; Thrane, S; Yde, CW | 1 |
| Hole, S; Lykkesfeldt, AE; Pedersen, AM; Yde, CW | 1 |
| Chen, H; Ding, HF; Dong, Z; Fang, D; Huang, S; Jing, Q; Lu, Y; Su, SB; Yang, L | 1 |
| Haga, Y; Kanda, T; Nakamoto, S; Nakamura, M; Okamoto, H; Sasaki, R; Shirasawa, H; Yokosuka, O | 1 |
| Bai, Y; Chen, Y; Dong, X; Han, Y; Jiang, S; Luo, SX; Wu, B; Zhang, H; Zhang, Y; Zhao, G; Zhong, S | 1 |
| Guo, Q; Jin, L; Kang, JD; Luo, QR; Luo, ZB; Wang, JX; Xing, XX; Xuan, MF; Yin, XJ; Zhang, GL; Zhu, HY | 1 |
| Cupido, T; Jones, NH; Kapoor, TM; Pisa, R; Steinman, JB | 1 |
14 other study(ies) available for triazoles and jnj-7706621
| Article | Year |
|---|---|
The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases.
Topics: Animals; Aurora Kinases; Cell Line, Tumor; Cells, Cultured; Cyclin-Dependent Kinases; Endothelial Cells; Female; HeLa Cells; Humans; Melanoma; Mice; Mice, Nude; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Triazoles; Xenograft Model Antitumor Assays | 2005 |
Synthesis and evaluation of N-acyl sulfonamides as potential prodrugs of cyclin-dependent kinase inhibitor JNJ-7706621.
Topics: Acylation; Animals; Cells, Cultured; Cyclin-Dependent Kinases; Mice; Mice, Nude; Models, Chemical; Prodrugs; Protein Kinase Inhibitors; Solubility; Sulfonamides; Triazoles | 2006 |
Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor.
Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Aurora Kinases; Biological Availability; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Enzyme Inhibitors; HeLa Cells; Humans; Mice; Mice, Knockout; Neoplasm Proteins; Protein Serine-Threonine Kinases; Triazoles | 2006 |
Active and passive tumor targeting of a novel poorly soluble cyclin dependent kinase inhibitor, JNJ-7706621.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Synergism; HeLa Cells; Humans; Lactones; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; Micelles; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyglactin 910; Protein Kinase Inhibitors; Solubility; Surface Properties; Triazoles; Xenograft Model Antitumor Assays | 2010 |
Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Aurora Kinases; Binding Sites; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Kinetics; Molecular Sequence Data; Piperazines; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Sequence Alignment; Triazoles | 2011 |
Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.
Topics: Animals; Antineoplastic Agents; Aurora Kinase A; Aurora Kinase B; Aurora Kinases; Bone Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cyclin-Dependent Kinases; Cytokinesis; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Mice, Nude; Mitosis; Neoplasms; Nocodazole; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Sarcoma, Ewing; Spindle Apparatus; Time Factors; Triazoles; Tubulin Modulators; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin B1; Dimerization; Humans; Imidazoles; Indoles; Intracellular Signaling Peptides and Proteins; M Phase Cell Cycle Checkpoints; Melanoma; Mice; Neoplasm Metastasis; Nocodazole; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-mdm2; Repressor Proteins; Sulfonamides; Triazoles; Tumor Suppressor Protein p53; Vemurafenib; Xenograft Model Antitumor Assays | 2013 |
A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells.
Topics: Apoptosis; Aurora Kinase A; Biomarkers, Tumor; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Cyanoacrylates; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Estradiol; Estrogen Antagonists; Fulvestrant; G2 Phase Cell Cycle Checkpoints; Humans; MCF-7 Cells; Myeloid Cell Leukemia Sequence 1 Protein; Protein Kinase Inhibitors; Pyridines; Receptors, Estrogen; RNA Interference; Survival Analysis; Tamoxifen; Triazoles | 2015 |
Aurora kinase A and B as new treatment targets in aromatase inhibitor-resistant breast cancer cells.
Topics: Aromatase Inhibitors; Aurora Kinase A; Aurora Kinase B; Breast Neoplasms; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; MCF-7 Cells; Organophosphates; Quinazolines; Small Molecule Libraries; Triazoles | 2015 |
Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression.
Topics: Animals; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Oncogene Proteins; Ovarian Neoplasms; Oxazoles; RNA, Small Interfering; Thiazoles; Triazoles | 2015 |
The sirtuin inhibitor sirtinol inhibits hepatitis A virus (HAV) replication by inhibiting HAV internal ribosomal entry site activity.
Topics: Amantadine; Animals; Antiviral Agents; Benzamides; Cell Line; Chlorocebus aethiops; COS Cells; Epigenesis, Genetic; Hepatitis A virus; Histone Deacetylase Inhibitors; Host-Pathogen Interactions; Humans; Internal Ribosome Entry Sites; Naphthols; Phosphoproteins; Protein Biosynthesis; RNA, Viral; Sirtuins; Triazoles; Virus Replication | 2015 |
Identification of Driver Genes and Key Pathways of Glioblastoma Shows JNJ-7706621 as a Novel Antiglioblastoma Drug.
Topics: Adult; Apoptosis; Aurora Kinase A; Brain Neoplasms; Cell Cycle; Cell Line; Cell Line, Tumor; Cytoskeletal Proteins; Disease-Free Survival; Female; Flow Cytometry; Glioblastoma; Humans; In Vitro Techniques; Kinesins; Male; Microtubule-Associated Proteins; Molecular Targeted Therapy; Nuclear Proteins; Prognosis; Protein Interaction Maps; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Survival Rate; Transcriptome; Triazoles; Tumor Stem Cell Assay | 2018 |
The cyclin-dependent kinase inhibitor, JNJ-7706621, improves in vitro developmental competence of porcine parthenogenetic activation and somatic cell nuclear transfer embryos.
Topics: Animals; Blastocyst; Embryo, Mammalian; Embryonic Development; Nuclear Transfer Techniques; Oocytes; Parthenogenesis; Protein Kinase Inhibitors; Swine; Triazoles | 2018 |
Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.
Topics: AAA Proteins; Adenosine Triphosphatases; Amitrole; Biochemical Phenomena; Catalytic Domain; Crystallography, X-Ray; Drug Design; Humans; Microtubules; Models, Molecular; Point Mutation; Protein Engineering; Spastin; Triazoles; Tubulin | 2019 |